International Symposium on Malignant Pleural Mesothelioma

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International Symposium on Malignant Pleural Mesothelioma LONDON 2015 Friday 6th & Saturday 7th November 2015 Jumeirah Carlton Tower Hotel Cadogan Place Knightsbridge London SW1X 9PY United Kingdom

Dear colleagues, It is my pleasure to welcome you to London, for our first international symposium on malignant pleural mesothelioma. The program is curated to include lectures from guest speakers across a range of specialties, including: thoracic surgery, medical and radiation oncology, immunology, radiology, respiratory medicine, pathology and specialist nurses of whom are the foremost experts in their respective fields. Our goal is to provide a global view on malignant pleural mesothelioma from diagnosis to established and future therapies. There will be plenty of time for interactive discussions, and with your active participation, we aim to make this symposium a memorable event and develop new sources of collaboration and friendship. I look forward to welcoming you to London. With kindest regards, Loic Lang-Lazdunski

PROGRAMME FRIDAY 6TH NOVEMBER 8.30 AM REGISTRATION & COFFEE 9.25 AM WELCOME & PRESENTATION OF THE SYMPOSIUM 9.30 AM DIAGNOSTIC PATHWAY & INTERVENTIONAL MEDICINE 11.00 AM BREAK 11.30 AM SURGERY IN MESOTHELIOMA: CURRENT TRENDS 1.00 PM LUNCH 2.00 PM RADIOTHERAPY IN MESOTHELIOMA 3.00 PM IMMUNOTHERAPY, GENE THERAPY & CELL THERAPY 4.30 PM BREAK 5.00 PM SECOND-LINE OPTIONS, SUPPORTIVE CARE & ALTERNATIVE MEDICINES SATURDAY 7TH NOVEMBER 9.00 AM TARGETED THERAPIES 11.00 AM QUESTIONS & ANSWERS 11.30 AM CONCLUSIONS & END OF CONFERENCE

TOPICS DIAGNOSTIC PATHWAY & INTERVENTIONAL MEDICINE CHAIR: BRIAN O CONNOR 9.30 AM - 11.00 AM Update on imaging of malignant pleural mesothelioma, Sujal Desai, King s College Hospital, London Medical thoracoscopy versus VATS: what is the gold standard? Alex West, Guy s and St Thomas Hospital, London Talc pleurodesis versus indwelling pleural catheter, Nick Maskell, University of Bristol SURGERY IN MESOTHELIOMA: CURRENT TRENDS CHAIR: LOIC LANG-LAZDUNSKI 11.30 AM - 1.00 PM What have we learnt from the past 20 years? Raja Flores, Mount Sinai Hospital, New York Accelerated radiotherapy and EPP, Marc De Perrot, University of Toronto Radical pleurectomy/decortication, Loic Lang-Lazdunski, The Lister Hospital, London RADIOTHERAPY IN MESOTHELIOMA CHAIR: DAVID LANDAU 2.00 PM - 3.00 PM Prophylactic radiotherapy: What is the current evidence? Neil Bayman, The Christie Clinic, Manchester Adjuvant radiotherapy. Pleural IMRT, David Landau, Guy s and St Thomas Hospital, London

IMMUNOTHERAPY, GENE THERAPY & CELL THERAPY CHAIR: DAN STERMAN 3.00 PM - 4.30 PM Intrapleural gene therapy, Dan Sterman, New York University Immunotherapy with T cells, CARs, John Maher, King s College London Immune checkpoint blockers, anti-mesothelin therapies, Arnaud Scherpereel, CHRU Lille Targeting mesothelioma with stem cells, Sam Janes, UCL, London SECOND-LINE OPTIONS, SUPPORTIVE CARE & ALTERNATIVE MEDICINES CHAIR: JEREMY STEELE 5.00 PM - 6.00 PM Systemic therapies: second-line options, Jeremy Steele, Barts and the London Optimising supportive care, Jane Lynch, Harley Street Clinic, London Chinese medicines and acupuncture in mesothelioma, Orrin Ezralow TBC TARGETED THERAPIES CHAIR: SANJAY POPAT 9.00 AM - 11.00 AM How can pathologists help choose the best therapy? Andrew Nicholson, Royal Brompton Hospital, London Molecular pathways and drug development, Tobias Arkenau, Sarah Cannon Research Institute, London Personalised therapy in mesothelioma, Paul Baas, The Netherlands Cancer Institute, Amsterdam Xenografts and omics, Justin Stebbing, Imperial College London

FACULTY Dr Tobias Arkenau, Consultant Medical Oncologist, Medical Director, Sarah Cannon Research Institute, London Dr Paul Baas, Professor of Thoracic Oncology, University of Amsterdam, Chief of Thoracic Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital Dr Neil Bayman, Consultant Clinical Oncologist, The Christie NHS Foundation Trust, Manchester Dr Marc de Perrot, Staff surgeon, Division of Thoracic Surgery, Toronto General Hospital and Associate Professor Division of Thoracic Surgery, University of Toronto Dr Sujal Desai, Consultant Thoracic Radiologist, King s College Hospital, London Dr Orrin Ezralow, Specialist in Chinese Medicine and Acupuncture TBC Dr Raja Flores, Chief Division of Thoracic Surgery, Mount Sinai Hospital, New York and Professor of Thoracic Surgery, Icahn School of Medicine at Mount Sinai, New York Dr Samuel Janes, Consultant in Respiratory Medicine, University College Hospital NHS Foundation Trust, Professor Department of Medicine, University College London Dr David Landau, Consultant Clinical Oncologist, Guy s and St Thomas Hospital, London Dr Loic Lang-Lazdunski, Professor of Thoracic Surgery, The Lister Hospital, London Mrs Jane Lynch, Lung Cancer and Mesothelioma Nurse Specialist, Harley Street Clinic, London Dr John Maher, Clinical Senior Lecturer and Consultant Immunologist, Division of Cancer Studies, King s College, London

Dr Nick Maskell, Consultant in Respiratory Medicine, Professor of Respiratory Medicine, University of Bristol Dr Andrew Nicholson, Consultant Histopathologist, Royal Brompton and Harefield NHS Foundation Trust, Professor of Respiratory Pathology, National Heart and Lung Institute, Imperial College London Dr Brian O Connor, Consultant Physician in Respiratory Medicine, The Lister Hospital, London Dr Sanjay Popat, Consultant Medical Oncologist and Senior Lecturer, The Royal Marsden Hospital, London Dr Arnaud Scherpereel, Chief of Pulmonology and Thoracic Oncology, Centre Hospitalier Universitaire de Lille, Professor of Pulmonology, University of Lille Dr Justin Stebbing, Consultant Medical Oncologist, Imperial College NHS Trust and Professor of Cancer Medicine and Oncology, Imperial College London Dr Jeremy Steele, Consultant Medical Oncologist, Barts and the London NHS Foundation Trust, London Dr Daniel Sterman, Professor of Pulmonary Medicine and Critical Care, Department of Medicine, New York University School of Medicine, Chief of the Division of Pulmonary Medicine, Critical Care and Sleep Medicine NYU Langone Medical Center Dr Alex West, Consultant in Respiratory Medicine, Guy s and St Thomas NHS Foundation Trust, London

COSTS FOR ATTENDING Consultants 125 Trainees & Nurses 95 General Public 95 Jumeirah Carlton Tower Hotel The essence of Knightsbridge, Jumeirah Carlton Tower is ideally located on Sloane Street, one of the world s most exclusive shopping havens. From the prestigious department stores to the myriad of designer boutiques, you will experience world class shopping, dining and relaxation at its best. Bedroom Rates Friday 6th November 2015 Jumeriah Carlton Tower @ 239.00 Friday 6th November 2015 Jumeriah Lowndes Hotel @ 179.00 Please note that our bedroom rates are exclusive of VAT and breakfast Rates are quoted per room, per night and are quoted for single or double occupancy Rates are subject to VAT, currently at 20%, and are quoted on a room only basis Rates exclude a discretionary service charge of 5% All rates are in English pounds ( ). Breakfast is available at 39.00 for English breakfast or 32.00 for Continental breakfast. Please note: if you require details of additional hotels, contact mesothelioma@hcahealthcare.co.uk