Advances in Colorectal Cancer From Screening to Innovative Care

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virginia mason continuing medical education Advances in Colorectal Cancer From Screening to Innovative Care Presented by The Cancer Institute and Digestive Disease Institute at Virginia Mason Friday, March 8, 2019 Virginia Mason Seattle, Washington

Faculty course directors Hagen F. Kennecke, MD, MHA, FRCPC Medical Director, Cancer Institute Virginia Mason, Seattle, Wash. Michael C. Larsen, MD Digestive Disease Institute at Virginia Mason, Seattle, Wash. Ravi Moonka, MD, FACS Colorectal Surgeon Digestive Disease Institute at Virginia Mason, Seattle, Wash. keynote speaker Nancy E. Kemeny, MD Oncologist Memorial Sloan Kettering Cancer Center, New York City, NY guest faculty Joseph Carmichael, MD, FASCRS Surgeon University of California, Irvine Sharlene Gill, MD, MPH, MBA, FRCPC Professor of Medicine BC Cancer Agency, University of British Columbia, Vancouver, BC, Canada Skye Mayo, MD, MPH Surgical Oncologist Oregon Health and Science University, Portland, OR Deborah Italiano, BSN, RN, OCN Memorial Sloan Kettering Cancer Center, New York City, NY virginia mason faculty Shayan Irani, MD Associate Director, Pancreatic Center of Excellence Vicky Jones, MD Oncologist, North Star Lodge Cancer Center Bruce Lin, MD Hematologist-Oncologist Otto Lin, MD Director, Quality Improvement Patrick C. Marcin, MD Radiologist Fran J. O Donnell, BSN, RN, CWCN Acute Care, Ambulatory Surgery Wound Care Center Huong Pham, MD Radiation Oncologist Flavio G. Rocha, MD, FACS HPB Surgical Oncologist Director of Research, Digestive Disease Institute Associate Medical Director, Cancer Institute Vlad V. Simianu, MD, MPH Colorectal Surgeon Neil Wiegand, PA-C, MCHS Physician Assistant, General and Colorectal Surgery

Advances in Colorectal Cancer From Screening to Innovative Care Presented by The Cancer Institute and Digestive Disease Institute at Virginia Mason Colorectal cancer is the #2 cause of cancer death in North America. While we successfully screen for colorectal cancer, many gaps in evidence-based treatment remain. Current practitioners have questions about the role of circulating tumor DNA in the diagnosis and management of early to advanced colorectal cancer; the role of endoscopic microsurgery in the management of colon cancer; and when full oncologic surgery is required to deliver the most appropriate care for colon cancer. For patients with advanced, unresectable disease, how can hepatic intra-arterial (HIA) chemotherapy allow surgical resection of previously unresectable liver metastasis? What are the latest evidence and guidelines for diagnosis and treatment of colorectal cancer? Join our renowned, multidisciplinary faculty for this stimulating day of learning. Teaching methods include lecture, question and answer with faculty, panel discussion and case presentation. target audience: This symposium is designed for all healthcare professionals interested in the screening, evaluation, and management of patients with or at risk for colorectal cancer, including MDs, advanced practitioners, and nurses in oncology, surgery, gastroenterology, and primary care, and administrators of those service lines. objectives: At the conclusion of this activity, participants should be able to: Discuss how hepatic arterial infusional (HIA) therapy works Review current systemic therapy options for the treatment of advanced colorectal cancer Summarize consensus recommendations for liver-limited metastatic colorectal cancer Describe the HIA Program Development experience at an academic medical center Review novel approaches to hepatic arterial therapy List requirements for intrahepatic chemotherapy Discuss management of unresectable metastatic colorectal cancer with liver metastases only and of unresectable metastatic colorectal cancer with liver and lung metastases Review ACS guidelines for colorectal cancer screening and the data behind them Outline how to screen for intra-epithelial lesions and how HRA is performed Specify the preferred diagnostic and staging for anal cancer Select candidates for a watch and wait approach to rectal cancer treatment per NCCN guidelines and current medical literature Summarize the current applications and limitations of transanal approaches to cancer Describe technical considerations and modalities concerning local excision for rectal cancer Differentiate endoscopic from TAMIS/TEMS in the treatment of rectal cancer Discuss loco-regional and systemic management of early stage NETS Assess the patient perspective of colostomy management Compare treatment of Stage I, Stage II, and Stage III Rectal Cancer Virginia Mason Medical Center is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Credit Designation: Virginia Mason Medical Center designates this live activity for a maximum of 6.25 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 6.25 MOC points in the American Board of Internal Medicine s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of

Agenda 7:00 a.m. Registration opens, breakfast selection available 7:30 a.m. Grand Rounds Presentation: Can We Cure Metastatic Colon Cancer? The Use of Hepatic Arterial Therapy Nancy Kemeny, MD 8:30 a.m. Break 8:45 a.m. Opening Remarks Hagen Kennecke, MD advanced colorectal cancer 8:50 a.m. Advances in Management of Advanced Colorectal Cancer Sharlene Gill, MD 9:10 a.m. Surgical Management of Liver-Limited Metastatic Colorectal Cancer Flavio Rocha, MD 9:30 a.m. Building an HIA Program: the OHSU Experience Skye Mayo, MD 9:50 a.m. Locoregional Therapies for Colorectal Liver Metastases Patrick Marcin, MD 10:10 a.m. Treatment Administration Intrahepatic Chemotherapy Deborah Italiano, RN 10:30 a.m. Panel Discussion: Case Presentations Moderator: Bruce Lin, MD 10:50 a.m. Break 11:10 a.m. New ACS Guidelines for Colorectal Cancer Screening Otto Lin, MD 11:30 a.m. Anal Dysplasia and Cancer Screening, Treatment and Prevention Neil Wiegand, PAC 11:50 a.m. Updates in Management and Surveillance of SCC Anal Cancer Huong Pham, MD 12:10 p.m. Lunch (provided) screening and non-surgical treatment of disease 1:00 p.m. Management of Rectal Cancer: Trends and Trials Joseph Carmichael, MD 1:20 p.m. Debate: Transanal Minimally Invasive Surgery (TAMIS) and Transanal Endoscopic Microsurgery (TEMS) as Optimal Therapy for Early Rectal Cancer Vlad Simianu, MD 1:40 p.m. Debate: Total Mesorectal Excision (TME) Remains the Standard First Line Therapy for Early Rectal Cancer Ravi Moonka, MD 2:00 p.m. Endoscopic Treatments for Early Colorectal Cancer and Advanced Colon Polyps Shayan Irani, MD 2:20 p.m. Break 2:40 p.m. Colorectal Neuroendocrine Tumors Hagen Kennecke, MD 3:00 p.m. Colostomy Management and Patient Perspectives Fran O Donnell, RN 3:20 p.m. Rectal Cancer Cases Vicky Jones, MD 3:40 p.m. Closing Remarks, Adjourn CME credits claimed for the activity. It is the CME activity provider s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Application for CME credit has been filed with the American Academy of Family Physicians (AAFP). Determination of credit is pending. Virginia Mason is a provider of nursing continuing education contact hours. Provider is approved by the California Board of Registered Nursing, Provider #CEP15905 for 6.25 Contact Hours (6.25 clock hours), March 8, 2019. Location: The course will be held in Volney Richmond Auditorium on Level One of the Virginia Mason Lindeman Pavilion, 1201 Terry Avenue, Seattle (between Seneca & University Streets.) Please note the Terry Street entrance into Lindeman Pavilion is Level Two. For information, contact the CME Department at 206-341-0142 or email cme@virginiamason.org.

To register, complete the form below and send via: Mail: Virginia Mason CME Dept. 1100 9th Ave, D3-CME Seattle, WA 98101 Phone: (206) 341-0142 fax: (206) 341-1480 e-mail: cme@virginiamason.org web: VirginiaMasonCME.org Cancellation and Refund Policy: Refunds will be made for a fee of $25 if written notice of cancellation is received at least 14 calendar days prior to the activity. registration: Advances in Colorectal Cancer Friday, March 8, 2019 Please print clearly name degree/credentials specialty organization address city/state/zip phone e-mail Please provide one question for the faculty: I will attend at the Videoconferencing Site in: For information, call (206) 341-0142. Please add me to your e-mail list for news of upcoming CME courses at Virginia Mason. payment: Tuition: $195.00 Check enclosed. Make check payable to VMMC CME Please charge my: VISA MasterCard American Express Discover card number expiration date cardholder name signature