OIE Collaborating Centres Reports Activities Activities in 2017 This report has been submitted : 2017-12-13 11:14:09 Title of collaborating centre: Food-Borne Parasites from the Asia-Pacific Region Address of Collaborating Centre: Ministry of Education Institute of Zoonosis Jilin University 5333 Xian Road 130062 Changchun CHINA (PEOPLES REP. OF) Tel.: +86-431 87.83.67.02 Fax: E-mail address: liumy@jlu.edu.cn Website: Name of Director of Institute (Responsible Official): Liu Mingyuan Name (including Title and Position) of Head of the Collaborating Centre (formally OIE Contact Point): Liu Mingyuan, Ph.D. Director of Institute of Zoonosis,Jilin University; Name of writer: Wang Xuelin OIE Collaborating Centres Reports Activities, 2017 1
ToR: To provide services to the OIE, in particular within the region, in the designated specialty, in support of the implementation of OIE policies and, where required, seek for collaboration with OIE Reference Laboratories ToR: To identify and maintain existing expertise, in particular within its region 1. Activities as a centre of research, expertise, standardisation and dissemination of techniques within the remit of the mandate given by the OIE Disease control Serological diagnosis for Clonorchis sinensis, Toxoplasma,Cryptosporidium, Trichinella Farm pigs,dogs,pet cats in China Prokaryotic expression and site directed mutagenesis of T668 antigen gene of Trichinella spiralis Farm pigs and dogs in northeast of China Clone and expression characterization with DNase Ⅱ- T3223-7 gene of Trichinella spiralis adults Farm pigs and dogs in northeast of China Strategy and policy stipulation for prevention of trichinella spiralis, Clonorchis sinensis, Toxoplasma and Cryptosporidium Farm pigs, dogs and cats in China Toxoplasmosis development and application of novel methods for source attribution Farm pigs in China Epidemiology, surveillance, risk assessment, modelling Prevalence survey on trichinellosis Prevalence survey on Toxoplasmosis swine and dogs in eastern Inner Mongolia pigs in US Training, capacity building 200 permanent staffs of training Working in animal CDC of Jilin province,china Zoonoses Development and harmonization of diagnostic methods in animals and humans Current Research of Trichinellosis Key parasitic zoonosis prevention and controlling Trichinella spiralis, Clonorchis sinensis, Toxoplasma and Cryptosporidium in host animal and human of China in China Farm pigs in China(supporting by Ministry of Science and Technology,China ) Aquatic animal diseases 2 OIE Collaborating Centres Reports Activities, 2017
Anisakid survey 400 fish samples from Coastline of Southeast Asia Animal welfare Animal health product consulation Prof Liu Mingyuan,Wang Xuelin and Liu Zengshan worked in OIE Collaborating Center for Food-borne Parasites from Asian-Pacific Region serve for farm animal and pets Diagnosis, biotechnology and laboratory A serological commercial kit based on E/S antigen of Trichinella was set up in China For epidemiological survey in human and pigs A serological commercial kit based on E/S antigen of Toxoplasmosis was set up in China For epidemiological survey in human and pigs Veterinary medicinal products Study on interference effect of the TLR8 receptor agonist on the Trichinella spiralis - infected mouse For farm pigs Vaccines Recombinant Trichinella pseudospiralis Serine Protease Inhibitors Alter Macrophage Polarization In Vitro For farm pigs Influence of adjuvant formulation on inducing immune response in mice immunized with a recombinant serpin from Trichinella spiralis For farm pigs Immune Cell Responses and Cytokine Profile in Intestines of Mice Infected with Trichinella spiralis For farm pigs and Human Immunoproteomic analysis of the excretory-secretory products of Trichinella pseudospiralis adult worms and newborn larvae For farm pigs and Human Recombinant Trichinella pseudospiralis Serine Protease Inhibitors Alter Macrophage Polarization In Vitro For farm pigs and Human Food safety Improvement Sero-Surveillance of Trichinella, the only EC regulated mandatory controlled foodborne zoonotic parasite. In China ToR : To propose or develop methods and procedures that facilitate harmonisation of international standards and guidelines applicable to the designated specialty 2. Proposal or development of any procedure that will facilitate harmonisation of international OIE Collaborating Centres Reports Activities, 2017 3
regulations applicable to the surveillance and control of animal diseases, food safety or animal welfare Proposal title /Content Applicable area 1. International multilateral cooperation OIE Reference Centres Surveillance and control of animal diseases Food safety Animal welfare ToR: To establish and maintain a network with other OIE Collaborating Centres designated for the same specialty, and should the need arise, with Collaborating Centres in other disciplines ToR: To carry out and/or coordinate scientific and technical studies in collaboration with other centres, laboratories or organisations 3. Did your Collaborating Centre maintain a network with other OIE Collaborating Centres (CC), Reference Laboratories (RL), or organisations designated for the same specialty, to coordinate scientific and technical studies? Yes Name of OIE CC/RL/other organisation(s) Location Region of networking Centre Purpose OIE CC for Food-borne Parasites in European France Africa Americas Asia and Pacific Europe Middle East Cooperation in controlling foodborne zoonotic parasite OIE CC for Food-borne Parasites in North America Canada Africa Americas Asia and Pacific Europe Middle East Cooperation in parasite epidemiology 4. Did your Collaborating Centre maintain a network with other OIE Collaborating Centres, Reference laboratories, or organisations in other disciplines, to coordinate scientific and technical studies? No ToR: To place expert consultants at the disposal of the OIE. 5. Did your Collaborating Centre place expert consultants at the disposal of the OIE? 4 OIE Collaborating Centres Reports Activities, 2017
Yes Name of expert Kind of consultancy Subject Liu Mingyuan diagnosis, molecular typing diagnosis. Surveillance of epidemiology. Wang Xuelin diagnosis, molecular typing diagnosis. Trichinella sp,anisakidae,clonorchis,cysticercus,toxoplasma,cryptosporidium,giardia Zhu Guan diagnosis, molecular typing diagnosis Pascal diagnosis, molecular typing diagnosis Zhang Xichen diagnosis, molecular typing diagnosis ToR: To provide, within the designated specialty, scientific and technical training to personnel from OIE Member Countries 6. Did your Collaborating Centre provide scientific and technical training, within the remit of the mandate given by the OIE, to personnel from OIE Member Countries? No ToR: To organise and participate in scientific meetings and other activities on behalf of the OIE 7. Did your Collaborating Centre organise or participate in the organisation of scientific meetings on behalf of the OIE? Yes National/International Title of event Co-organiser Date (mm/yy) Location No. Participants International Regional Meeting of OIE Reference Centers in Asia and the Pacific no 6-7 February 2017 Tokyo, Japan 1 OIE Collaborating Centres Reports Activities, 2017 5
ToR: To collect, process, analyse, publish and disseminate data and information relevant to the designated specialty 8. Publication and dissemination of any information within the remit of the mandate given by the OIE that may be useful to Member Countries of the OIE a) Articles published in peer-reviewed journals: 6 [1] Ding J, Bai X, Wang X, Shi H, Cai X, Luo X, Liu M, Liu X. Immune Cell Responses and Cytokine Profile in Intestines of Mice Infected with Trichinella spiralis. Front Microbiol. 2017 Oct 31;8:2069. [2] Wang Y, Bai X, Zhu H, Wang X, Shi H, Tang B, Boireau P, Cai X, Luo X, Liu M, Liu X. Immunoproteomic analysis of the excretory-secretory products of Trichinella pseudospiralis adult worms and newborn larvae. Parasit Vectors. 2017 Nov 21;10(1):579. [3] Xu N, Liu X, Tang B, Wang L, Shi HN, Boireau P, Liu M1, Bai X. Recombinant Trichinella pseudospiralis Serine Protease Inhibitors Alter Macrophage Polarization In Vitro. Front Microbiol. 2017 Sep 21;8:1834. [4] Bai X, Hu X, Liu X, Tang B, Liu M. Current Research of Trichinellosis in China. Front Microbiol. 2017 Aug 2;8:1472. [5] Xu J, Bai X, Wang LB, Shi HN, VAN DER Giessen JWB, Boireau P, Liu MY, Liu XL. Immune responses in mice vaccinated with a DNA vaccine expressing serine protease-like protein from the new-born larval stage of Trichinella spiralis. Parasitology. 2017 May;144(6):712-719. [6] Xu J, Bai X, Wang LB, Shi HN, van der Giessen JWB, Boireau P, Liu MY, Liu XL. Influence of adjuvant formulation on inducing immune response in mice immunized with a recombinant serpin from Trichinella spiralis. Parasite Immunol. 2017 Jul;39(7). b) International conferences: 0 c) National conferences: 0 d) Other (Provide website address or link to appropriate information): 0 6 OIE Collaborating Centres Reports Activities, 2017