CARDIOLOGY HIGHLIGHTS IN. Rome, February 1 st - 3 rd, Aula Magna, Sapienza Università degli Studi di Roma

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SCIENTIFIC PROGRAM HIGHLIGHTS IN CARDIOLOGY President of the Congress Prof. Francesco Fedele Rome, February 1 st - 3 rd, 2017 Aula Magna, Sapienza Università degli Studi di Roma

SCIENTIFIC INFORMATION Prof. Francesco Fedele SCIENTIFIC COMMITTEE Simone Calcagno Viviana Maestrini Massimo Mancone

Dear Friend and Colleague, On behalf of the Organizing Committee, it is my great pleasure to welcome you to Rome and to the 1st Congress on Heart Disease Highlights in Cardiology. The Congress has been designed to provide an innovative and comprehensive overview of the latest research developments in cardiovascular medicine, primarily in the areas of cardiology basic sciences, coronary artery disease, heart failure and an overview about heart and sport. Many distinguished cardiologists and scientists have joined the faculty and will take part in this International Congress. The speakers coming from Europe, North and South America and Asia, will present in the plenary sessions, superb scientific material that was carefully selected by the Scientific committee. We explore the treatment of cardiovascular disease, have a special track on the most debated topics about heart failure and ischemic heart diseases, and have some fascinating lectures by the leading professional in our field. These presentations assure that the meeting will be a major scientific event. Our aims to explore, fuel spark and be part of the innovations that will shape the future of our cardiovascular systems and beyond. We hope that you will enjoy the Congress and that your interaction with your colleagues from many different countries will stimulate a creative exchange of ideas and will be personally rewarding. We also hope and trust that you will enjoy your visit to the very beautiful and exciting city of Rome, in February 2017. Yours sincerely, Francesco Fedele

PROGRAM WEDNESDAY, FEBRUARY 1 15.00 Registration 15.15 Introduction Cardiovascular prevention 15.30-17.20 SESSION I Heart & Sport: primary prevention Chairmen: P. Brady; M. Penco 15.30 Perinatal cardiovascular programming G. Mercuro 15.45 Sudden cardiac death in the athlete D. Corrado 16.00 Role of exercise test, provocative tests and cardiovascular imaging V. Maestrini 16.15 Is the ECG screening in all, athletes and no athletes, the answer? - Yes F. Fedele - No P. Brady 16.45 Not only heart E. Alleva 17.00 Discussion 17.20-19.35 SESSION II Cardiovascular disease between gender differences and new clinical scenarios Chairmen: L. Badimon; M. Di Biase 17.20 Women and cardiovascular disease R. Bugiardini

17.35 Cardioprotection and cardio-oncology C. Cadeddu Dessalvi 17.50 HIV and cardiovascular disease M. Mancone 18.05 Insulin resistance, metabolic syndrome and adrenergic activation: diabetic cardiomyopathy P. Perrone Filardi 18.20 Infective disease and cardiovascular pathology C. Chimenti 18.35 Discussion 18.55 OPEN CEREMONY Eugenio Gaudio, Rector of Sapienza University of Rome Domenico Alessio, General Manager of Azienda Ospedaliera Universitaria Policlinico Umberto I Sebastiano Filetti, Dean of Medicine and Odontology, Sapienza University of Rome 19.05 LECTURE Chairman: F. Fedele The essential role of educational development: ACC prespective P. O Gara 19.35 Welcome cocktail

THURSDAY, FEBRUARY 2 08.45 Introduction New knowledge in ischemic heart disease: basic science and clinical scenario 09.15-11.30 SESSION III Basic Science Which is the protagonist in the ischemic heart/atherosclerotic disease development? Chairmen: W. Chilian; F. Fedele 09.15 Role of the oxldl and the inflammatory process F. Romeo 09.30 Microcirculation dysfunction in different clinical settings P. G. Camici 09.45 Role of the cardiac adrenergic innervation and microvascular constriction F. Crea 10.00 Role of mitochondrial oxidative stress in the coronary vessel W. Chilian 10.15 Role of cardiac metabolism: crosstalk between myocardial energy state and coronary blood flow P. Severino 10.30 Discussion 11.00 LECTURE Chairman: F. Fedele Cardiovascular disease in China L. Jiang 11.30 Coffee break 11.45-13.30 SESSION IV Clinical scenario Acute coronary syndromes: from latest trials to clinical practice Chairmen: P. Casale; G. Sardella 11.45 Pretreatment with P2Y12 receptor inhibitors: pro and con C. Collet Bortone

12.00 Cardiovascular disease and diabetes: a critical evaluation of recent outcome trials F. Cosentino 12.15 Bioresorbable vascular scaffold: the present and the future R. Diletti 12.30 Thrombectomy during primary PCI G. Sardella 12.45 Cardiogenic shock: pharmacological and non-pharmacological therapies M. Mancone 13.00 Discussion 13.30 Lunch 14.30-17.15 SESSION V Chronic ischemic heart disease: new pharmacological approach Chairmen: G. Ambrosio; F. Cosentino 14.30 Dual antiplatelet therapies issue in: - Atrial fibrillation patient G. Patti - Elective non-cardiac surgery P. Casale 15.00 The new drugs for the residual/persistent angina S. Calcagno 15.15 Acid uric a new therapeutic target G. Ambrosio 15.30 Treating hypercholesterolemia: more than statins F. Adamo 15.45 Discussion 16.15 Best abstract award Chairmen: M. Di Biase; F. Romeo 17.15 End of sessions

FRIDAY, FEBRUARY 3 08.45 Introduction Heart failure: translating evidences in clinical practice 09.15-11.00 SESSION VI Heart failure as multi-organ syndrome Chairmen: L. Dei Cas; S. Novo 09.15 Lung involvement C. D.Vizza 09.30 Renal involvement S. Mazzaferro 09.45 Liver involvement G. Sinagra 10.00 Brain involvement D. Toni 10.15 HLM: the new TNM-like classification for heart failure F. Fedele 10.30 Discussion 11.00 Coffee break 11.15-13.30 SESSION VII Clinical scenario Advanced heart failure: from drugs to device to stem cells Chairmen: G. Mazzesi; L. Padeletti 11.15 The use of new ICDs in the primary prevention C. Lavalle 11.30 Mechanical therapy F. Miraldi 11.45 Pharmacological therapy: new inotropes M. Metra 12.00 Hemodynamic support and VAD P. Mather

12.15 Stem cells and cardiac regeneration D. Torella 12.30 Discussion 13.00 LECTURE Chairman: F. Fedele Surgical treatment of heart failure: the past, present and future O. Alfieri 13.30 Lunch 14.30-17.00 SESSION VIII Heart failure and imaging evaluation Chairmen: F. Gentile; R. E. Dulgheru 14.30 Left ventricular function evaluation R. E. Dulgheru 14.45 Right ventricular function P. Marino 15.00 Strategies to assess valve involvement G. La Canna 15.15 Fibrosis in non-ischemic cardiac diseases V. Maestrini 15.30 Viable versus non viable myocardium L. Agati 15.45 Endomyocardial biopsy A. Frustaci 16.00 Discussion 16.30 LECTURE Chairman: F. Fedele Heart failure between clinical evaluation and multimodality imaging S. Murali 17.00 CME evaluation and conclusions

GENERAL INFORMATION CONGRESS VENUE Aula Magna del Rettorato - Sapienza Università degli Studi di Roma Piazzale Aldo Moro, 5 00185 Rome, Italy REGISTRATION Registration is free. The registration form is available on the website: www.mcrconference.it The organizing secretariat will confirm in writing the approval of the registration. CME CREDITS (only for Italian physicians) Provider C.M.E. MCR Conference Srl ID 489 Event Number 176745 - N. 7 Assigned credits The congress is accredited for the Italian physicians, in accordance with the existing national laws on CME. Profession: Physicians Reserved to the following categories: Anesthesiology and Intensive Care, Cardiology, General Medicine, Cardiac Surgery, Internal Medicine. CONFERENCE LANGUAGE English is the official language.

SPEAKERS AND CHAIRMEN Francesco Adamo, Rome I Luciano Agati, Rome I Ottavio Alfieri, Milan I Enrico Alleva, Rome I Giuseppe Ambrosio, Perugia I Lina Badimon, Barcellona ES Peter Brady, Rochester USA Raffaele Bugiardini, Bologna I Christian Cadeddu Dessalvi, Cagliari I Simone Calcagno, Rome I Paolo G. Camici, Milan I Paul Casale, New York USA William Chilian, Rootstown USA Cristina Chimenti, Rome I Carlos Collet Bortone, Amsterdam NL Domenico Corrado, Padova I Francesco Cosentino, Stockholm S Filippo Crea, Rome I Livio Dei Cas, Brescia I Matteo Di Biase, Foggia I Roberto Diletti, Rotterdam NL Raluca Elena Dulgheru, Liegi BE Francesco Fedele, Rome I Andrea Frustaci, Rome I Federico Gentile, Naples I Lixin Jiang, Beijing CN Giovanni La Canna, Milan I Carlo Lavalle, Rome I Viviana Maestrini, Rome I Massimo Mancone, Rome I Paolo Marino, Novara I Paul Mather, Philadelphia USA Sandro Mazzaferro, Rome I Giuseppe Mazzesi, Rome I Giuseppe Mercuro, Cagliari I Marco Metra, Brescia I Fabio Miraldi, Rome I Srinivas Murali, Pittsburgh USA Salvatore Novo, Palermo I Patrick O Gara, Boston USA Luigi Padeletti, Florence I Giuseppe Patti, Rome I Maria Penco, L Aquila I Pasquale Perrone Filardi, Naples I Francesco Romeo, Rome I Gennaro Sardella, Rome I Paolo Severino, Rome I Gianfranco Sinagra, Trieste I Danilo Toni, Rome I Daniele Torella, Catanzaro I Carmine Dario Vizza, Rome I

ORGANIZING SECRETARIAT MCR Conference Srl Via Finlandia, 26-50126 Florence, Italy Ph. 0039 055 4364475 info@mcrconference.it www.mcrconference.it