17 References/Resources Bassett, A. S., Scherer, S. W., & Brzustowicz, L. M. (2010). Copy number variations in schizophrenia: Critical review and new perspectives on concepts of genetics and disease. American Journal of Psychiatry, 167, 899-914. doi: 10 Bray, N., Leweke, F. M., Kapur, S., & Meyer-Lindeberg, A. (2010). The neurobiology of schizophrenia: New leads and avenues for treatment. Current Opinion in Neurobiology, 20, 810-815. doi: 10.1016/j.conb.2010.09.008 Corvin, A., Craddock, N., & Sullivan, P. F. (2010). Genome-wide association studies: A primer. Psychological Medicine, 40, 1063-1077. doi: 10.1017/s0033291709991723 Duan, J., Sanders, A. R., & Gejman, P. V. (2010). Genome-wide approaches to schizophrenia. Brain Research Bulletin, 83(3-4), 93-102. doi: 10.1016./jbrainresbull.2010.004.009 Feuk, L., Carson, A. R., & Scherer, S. W. (2006). Structural variation in the human genome. Nature Reviews Genetics, 7, 85-97. doi: 10.1038/nrg1767 Gejman, P. V., Sanders, A. R., & Duan, J. (2010). The role of genetics in the etiology of schizophrenia. Psychiatric Clinics North America, 33, 35-66. doi: 10.1016/j.psc.2009.12.003 Girard, S. L., Xiong, L., Dion, P. A., & Rouleau, G. A. (2011, January 27). Where are the missing pieces of the schizophrenia genetics puzzle? Current Opinion in Genetics & Development, 21, 310-316. doi: 10.1016/j.gde.2011.01.001 Greenwood, T. A., Lazzeroni, L. C., Murray, S. M., Calkins, K. S., Dobie, D. J., Green, M. F.,... Braff, D. L. (2011, April 15). Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the consortium of the genetics of schizophrenia. AJP in Advance. doi: 10.1176/appi/appl.ajp.2011.10050723
18 Insel, T. R. (2010). Rethinking schizophrenia. Nature, 468, 187-193. doi: 100.1038/nature09552 Korbel, J. (n.d). 1000 Genomes data tutorial at ASHG. Retrieved from http://www.genome.gov/pages/research/der/1000genomesprojecttutorials/structuralv ariants-jankorbel.pdf Lencz, T., Szeszko, P. R., DeRosse, P., Burdick, K. E., Bromet, E. J., Bilder, R. M., & Malhotra, A. K. (2010). A schizophrenia risk gene, ZNF804A, influences neuroanatomical and neurocognitive phenotypes. Neuropsychopharmacology, 35, 2284-2291. doi: 10.1038/npp2010.102 Levinson, D. F., Duan, J., Oh, S., Sanders, A. R., Shi, J., Zang, N.,... Gejman, P. V. (2011). Copy number variants in schizophrenia: Confirmation of previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications. American Journal of Psychiatry, 302-316. doi: 10.1176/appi.ajp.2010.1006876 McClay, J. L., Adkins, D. E., Alberg, K., Bukszar, J., Kachane, A. N., Keefe, R. S.,... van den Oord, E. J. (2011). Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia. Neuropsychopharmacology, 616-626. doi: 10.1038/nnp2010.193 Meyer, U., Schwarz, M., & Muller, N. (2011). Inflammatory processes in schizophrenia: A promising neuroimmunological target for treatment of negative/cognitive symptoms and beyond. Pharmacology & Therapeutics, 132, 96-110. doi: 10.1016/jpharmthera.2011.06.003 Mitchell, K. J., & Porteous, D. J. (2011). Rethinking the genetic architecture of schizophrenia. Psychological Medicine, 41, 19-32. doi: 10.1017/S003329171000070X
19 National Institutes of Health (n.d). National Human Genome Research Institute. Retrieved from http://www.genome.gov/gwastudies/ National Institutes of Health. (n.d). National Library of Medicine. Retrieved from http://www.nlm.nih.gov/ O Connell, G., Lawrie, S., Mcintosch, A. M., & Hall, J. (2011). Schizophrenia risk genes: Implications for future drug development and discovery. Biochemical Pharmacology, 81, 1367-1373. doi: 10.1016/jbcp.2010.11.009 O Donovan, M., Craddock, N., Norton, N., Williams, H., Peirce, T., Moskvina, V., Nikolov, I.,... Owen, M. (2008). Identification of loci associated with schizophrenia by genomewide association and follow-up. Nature Genetics, 40, 1053-1055. doi: 10.1038/ng201 Pogue-Geille, M. F., & Yokley, J. (2010). Current research on the genetic contributors to schizophrenia. Current Directions in Psychological Science, 19(4), 214-219. doi: 10.1177/096372140378490 SGENE. (n.d).. Retrieved from http://www.sgene.eu/index.php Schizophrenia genetics. Retrieved from http://www.schizophreniaforum.org/new/detail.asp?id=1582 Schizophreniagene database. Retrieved from http://www.szgene.org/ Sebat, J., Levy, D., & McCarthy, S. (2009). Rare structural variants in schizophrenia: One disorder, multiple mutations; One mutation multiple disorders. Trends in Genetics, 25, 528-535. doi: 10.1016/j.tig.2009.10.004 Shi, J., Levinson, D. F., Duan, J., Sanders, A. R., Zheng, Y., Pe er, I.,... Gejman, P. V. (2009). Common variants on chromosomes 6p22.1 are associated with schizophrenia. Nature, 460, 753-757. doi: 10.1038/nature08192
20 Stefansson, H., Ophoff, R. A., Steinberg, S., Andreassen, O. A., Cichon, S., Rujescu, D.,... Collier, D. A. (2009). Common variants conferring risk of schizophrenia. Nature, 460, 744-748. doi: 10.1038/nature08186 The Schizophrenia Psychiatric Genome-Wide Study (GWAS) Consortium (in press). Genomewide association study of schizophrenia identifies five novel loci. Nature Genetics. The University of Utah. (n.d). Learn.Genetics. Retrieved from http://learn.genetics.utah.edu/content/epigenetics/ Vassos, E., Collier, D. A., Holden, S., Patch, C., Rujescu, D., St. Clair, D., & Lewis, C. (2010). Penetrance for copy number variants associated with schizophrenia. Human Molecular Genetics, 19, 3477-3481. doi: 10.1093/hmg/ddq259 Williams, H. J., Norton, N., Dwyer, S., Moskvina, V., Nikolov, I., Carroll, L.,... O Donovan, M. C. (2011). Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder. Molecular Psychiatry, 16, 429-441. doi: 10.1038/mp.2010.36 Wu, E. Q., Birnbaum, H. G., Shi, L. S., Ball, D. E., Kessler, R. C., Moulis, M., & Aggarwal, J. (2005). The economic burden of schizophrenia in the United States in 2002. The Journal of Clinical Psychiatry, 66, 1122-1129.