Pandemic (H1N1) (August 14, h GMT; 12 h EST) Update on the Qualitative Indicators

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Regional Update Pandemic (H1N1) 2009 (August 14, 2009-17 h GMT; 12 h EST) Update on the Qualitative Indicators For epidemiological week 31 (EW 31, August 2 to August 8) 17 countries have reported updated information to the Pan American Health Organization (PAHO) regarding the qualitative indicators 1 to monitor the pandemic (H1N1) 2009 (Table 1). Data from the most recent week of notification is considered for the purposes of the analysis below (EW 28 31). Of the 24 countries with information available, 8 countries (Bolivia, Brazil, Cuba, Ecuador, El Salvador, Guatemala, Mexico and Paraguay) reported experiencing moderate impact on health care services. For EW 31, no country reported a severe impact on health care services (Map 4). Presently, 22 countries in the Region report having widespread geographical distribution of the pandemic (H1N1) 2009 virus. Brazil reported that the geographical distribution is more limited during EW 31, thus its status changed from widespread to regional spread. Barbados reported information on geographical spread of pandemic influenza activity for the first time, reporting widespread distribution for EW 31. While Saint Kitts and Nevis informed having localized activity of pandemic influenza last week, on EW 31 their status has changed to no activity (Map 1). Four countries reported an increasing trend of respiratory disease, namely Belize, Haiti, Peru, and Saint Lucia. Three countries (Bolivia, Guatemala and Paraguay) that have reported increased trend in previous week, reported unchanged trend in the EW 31 (Map 2). Regarding the intensity of acute respiratory disease when comparing to the same period in previous years, Mexico reported having a very high intensity for EW 31, an increase from previous week. Argentina, Canada, Cuba, El Salvador, Guatemala, and Paraguay maintained their status of high intensity (Map 3). For the last four epidemiological weeks, Mexico reported having a decreasing trend of respiratory diseases. Nevertheless, the intensity of acute respiratory disease increased from high in the previous three epidemiological weeks to very high in EW 31 Paraguay had changed the report on trend of respiratory disease activity from increasing to decreasing during EW 31. However, they continue to report having high intensity of acute respiratory disease. Argentina, Chile, and Venezuela report a decreasing trend since EW 29, upon an increasing trend until EW 28. The World Health Organization (WHO) does not recommend any restrictions to travel or closing borders due to pandemic (H1N1) 2009. 1 See Table 4

Table 1. Weekly monitoring of qualitative indicators for the Pandemic (H1N1) 2009. Last Epidemiological Week available. Americas Region Country Geographic spread Trend Intensity Impact on Health Care Services EW Antigua and Barbuda Regional Unchanged Low or moderate Low Not specified Argentina Widespread Decreasing High Low 31 Bahamas Regional NIA NIA NIA 28 Barbados Widespread NIA Low or moderate NIA 31 Belize Localized Increasing NIA NIA 28 Bolivia Widespread Unchanged Low or moderate Moderate 31 Brazil Regional Unchanged Low or moderate Moderate 31 Canada Widespread Decreasing High NIA 29 Chile Widespread Decreasing Low or moderate Low 31 Colombia Widespread Unchanged Low or moderate Low 31 Costa Rica Widespread NIA NIA NIA 28 Cuba Regional Unchanged High Moderate 29 Dominica No activity Unchanged Low or moderate Low 31 Dominican Republic Widespread Decreasing Low or moderate Low 30 Ecuador Widespread Unchanged Low or moderate Moderate 31 El Salvador Widespread Decreasing High Moderate 31 Grenada Localized Unchanged Low or moderate Low 31 Guatemala Widespread Unchanged High Moderate 31 Guyana Localized NIA NIA NIA 28 Haiti Localized Increasing NIA Low Not specified Honduras Widespread NIA NIA NIA 28 Jamaica Widespread Decreasing Low or moderate Low Not specified Mexico Widespread Decreasing Very High Moderate 31 Nicaragua Widespread NIA NIA NIA 28 Panama Widespread Decreasing Low or moderate Low 31 Paraguay Widespread Decreasing High Moderate 30 Peru Widespread Increasing Low or moderate Low Not specified Saint Kitts and Nevis No activity Unchanged Low or moderate Low 31 Saint Lucia Widespread Increasing Low or moderate Low 31 Saint Vincent and the Grenadines Localized Unchanged NIA NIA 28 Suriname NIA NIA NIA NIA Trinidad and Tobago NIA NIA NIA NIA United States of America Widespread Decreasing Low or moderate Low 29 Puerto Rico (U.S.) Regional NIA NIA NIA 28 Virgin Islands (U.S.) NIA NIA NIA NIA 28 Uruguay Widespread Decreasing Low or moderate Low 30 Venezuela Widespread Decreasing Low or moderate Low 31 NIA: No Information Available Source: Ministries of Health of the countries in the Region 3

Update on the number of cases and deaths As of August 14, 2009, a total of 105,882 confirmed cases have been notified in all 35 countries in the Americas Region. A total of 1,579 deaths have been detected among the confirmed cases in 22 countries of the Region. Nicaragua and Venezuela reported their first deaths during EW 31. In addition to the figures displayed in Table 2, the following overseas territories have confirmed cases of pandemic (H1N1) 2009: American Samoa, U.S. Territory (8); Guam, U.S. Territory (1); Puerto Rico, U.S. Territory (20); Virgin Islands, U.S. Territory (49); Bermuda, UK Overseas Territory (1); Cayman Islands, UK Overseas Territory (14); British Virgin Islands, UK Overseas Territory (2); Turks and Caicos Islands (3); Martinique, French Overseas Community (15); Guadeloupe, French Overseas Community (11); Saint-Martin, French Overseas Community (4); Netherlands Antilles, Aruba (13); Netherlands Antilles, Bonaire (28); Netherlands Antilles, Curaçao (43)*; Netherlands Antilles, St. Eustatius (1); and Netherlands Antilles, St. Maarten (16). * Three cases were reported on a cruise-ship. The distribution of cases and deaths at the first subnational level can be found in the interactive map available through the following link: http://new.paho.org/hq/images/atlas/en/atlas.html 4

Table 2. Number of cases and deaths confirmed for the Pandemic (H1N1) 2009 virus Region of the Americas. Updated as of August 14, 2009 (17 h GMT; 12 h EST). Country Number of confirmed cases Number of deaths New cases (since August 7) New deaths (since August 7) Antigua & Barbuda 3 0 0 0 Argentina 6768 404 1058 66 Bahamas 23 0 0 0 Barbados 47 0 13 0 Belize 23 0 0 0 Bolivia 1069 13 116 4 Brazil* 2959 192 0 96 Canada* 10156 66 0 4 Chile** 12104 112 74 8 Colombia 298 18 23 1 Costa Rica 865 28 110 3 Cuba 264 0 0 0 Dominica 1 0 0 0 Dominican Republic 182 5 0 0 Ecuador 1039 23 158 5 El Salvador 626 12 58 3 Grenada 3 0 1 0 Guatemala 624 10 76 0 Guyana 7 0 0 0 Haiti 3 0 0 0 Honduras 278 7 24 1 Jamaica 64 4 0 1 Mexico 18390 162 974 16 Nicaragua 543 1 33 1 Panama 622 3 22 1 Paraguay 261 27 17 0 Peru 3559 23 0 0 Saint Kitts & Nevis 4 1 1 0 Saint Lucia 8 0 2 0 Saint Vincent & Grenadines 1 0 0 0 Suriname 11 0 0 0 Trinidad & Tobago 97 0 0 0 United States* 43771 436 0 83 Uruguay* 550 20 0 0 Venezuela 659 12 217 12 TOTAL 105882 1579 2977 305 Source: Ministries of Health of the countries in the Region *These countries no longer update on the total number of confirmed cases. However they do update the number of deaths. ** There are 352.742 cases compatible with the case definition; of those, 12,104 have been confirmed for the pandemic (H1N1) 2009 virus. 5

Update on the Virological Situation Virological data obtained from Ministry of Health websites, Ministry of Health reports to PAHO and notifications from National Influenza Centers (NICs) is included below. For the purposes of this analysis, only countries (or laboratories) that reported data on influenza sub type were considered. We excluded from the calculations of the percentages, results from samples of influenza that were not subtyped or were unsubtypeable. Virological information for countries (or laboratories) that provided that level of detail is display in Table 3. Among viruses that were subtyped as influenza A (seasonal H1, H3 or pandemic (H1N1) 2009), the predominant virus is the pandemic one (H1N1) 2009 in most countries for which information was available. Table 3. Relative circulation of pandemic (H1N1) for selected countries Country Epidemiological Pandemic (H1N1) 2009 % Week All subtyped influenza A Argentina 30 100% Brazil* 29 94.3% Canada 30 98.7% Chile 31 100.% Colombia 27 44.7% Costa Rica 17 25 99.8% Cuba 29 77.1% Panama 30 100% USA 30 99.0% MEDIAN 99.0% Source: Ministries of Health and National Influenza Centers of the countries in the Region * Data from Evandro Chagas Institute 6

Table 4. Qualitative indicators for the monitoring of pandemic (H1N1) 2009 Geographical spread: refers to the number and distribution of sites reporting influenza activity. No activity: Localized: Regional: Widespread: No information available: No laboratory confirmed case(s) of influenza, or evidence of increased or unusual respiratory disease activity. Limited to one administrative unit of the country (or reporting site) only. Appearing in multiple but <50% of the administrative units of the country (or reporting sites). Appearing in 50% of the administrative units of the country (or reporting sites). No information available for the previous 1 week period. Trend of respiratory disease activity compared to the previous week: refers to changes in the level of respiratory disease activity compared with the previous week. Increasing: Unchanged: Decreasing: No information available. Evidence that the level of respiratory disease activity is increasing compared with the previous week. Evidence that the level of respiratory disease activity is unchanged compared with the previous week. Evidence that the level of respiratory disease activity is decreasing compared with the previous week. Intensity of Acute Respiratory Disease in the Population: is an estimate of the proportion of the population with acute respiratory disease, covering the spectrum of disease from influenza like illness to pneumonia. Low or moderate: High: Very high: No information available. A normal or slightly increased proportion of the population is currently affected by respiratory illness. A large proportion of the population is currently affected by respiratory illness. A very large proportion of the population is currently affected by respiratory illness. Impact on Health Care Services: refers to the degree of disruption of health care services as a result of acute respiratory disease. Low: Moderate: Severe: No information available. Demands on health care services are not above usual levels. Demands on health care services are above the usual demand levels but still below the maximum capacity of those services. Demands on health care services exceed the capacity of those services. Source: Updated interim WHO guidance on global surveillance of human infection with pandemic (H1N1) 2009 virus. 10 July 2009. The data and information in this report will be updated on a weekly basis and available at: http://new.paho.org/hq/index.php?option=com_content&task=blogcategory&id=814&itemid=1206 This report was prepared based on the indicators in the document Human infection with pandemic (H1N1) 2009 virus: updated interim WHO guidance on global surveillance available at: (http://www.who.int/csr/disease/swineflu/notes/h1n1_surveillance_20090710/en/index.html). The information presented herein has been obtained through the official sites of the Ministries of Health of the countries in the Region as well as official reports submitted by the International Health Regulation (2005) National Focal Points. 7