Friday, May 18 09.00 Opening remarks L. Bolondi - Bologna (Italy) SESSION 1 THE ROLE OF CIRCULATING AND TISSUE BIOMARKERS Chair: J.C. Nault - Paris (France) 09.10 Predicting the development of HCC in liver cirrhosis E. Villa - Modena (Italy) 09.30 Circulating MiRNA for the diagnosis and staging of HCC L. Gramantieri - Bologna (Italy) 09.50 Discussion SESSION 2 NAFLD AND HCC Chair: S. Bellentani - Locarno (Switzerland) 10.00 Risk of cirrhosis and HCC in NAFLD: can be predicted and/or quantified? J.F. Dufour - Bern (Switzerland) 10.20 Genetic factors associated with HCC in NASH L. Valenti - Milan (Italy) 10.40 Recommendations for screening or surveillance for NAFLD E. Bugianesi - Turin (Italy) 11.15 Coffee-break 2
SESSION 3 DIAGNOSTIC DILEMMAS Chairs: R. Golfieri - Bologna (Italy), F. Trevisani - Bologna (Italy) 11.30 Time for new parameters in MRI for the diagnosis of HCC? R. Golfieri - Bologna (Italy) 11.50 LI RADS classification system, the issue of cholangiocarcinoma F. Piscaglia - Bologna (Italy) 12.10 Discussion 12.20 Round table debate starting from clinical cases Management of undefined small nodular liver lesion in cirrhosis Chair: L. Bolondi - Bologna (Italy) Discussants: M. Cescon - Bologna (Italy), J.F. Dufour - Bern (Switzerland) F. Piscaglia - Bologna (Italy), M. Renzulli - Bologna (Italy) 13.00 Lunch Friday, May 18 SESSION 4 ANTIVIRAL TREATMENT AND HCC Chairs: P. Andreone - Bologna (Italy), J. Bruix - Barcelona (Spain) 14.00 Treatment of HBV with antivirals and influence on the risk of HCC P. Lampertico - Milan (Italy) 14.20 Risk of development and natural history of HCC arisen in HCV patient with SVR after interferon based treatment S. Bhoori - Milan (Italy) 14.40 Treatment of chronic hepatitis C with IFN-free DAA regimens and risk of HCC M. Colombo - Milan (Italy) 15.00 Strategies for treatment of HCV with DAA after curative HCC treatment I do always treat C. Cammà - Palermo (Italy) I do not treat M. Reig - Barcelona (Spain) Sometimes I treat P.R. Galle - Mainz (Germany) 15.45 Discussion 16.00 Coffee-break 3
Friday, May 18 SESSION 5 CHALLENGES IN CURRENT SYSTEMIC THERAPY FOR HCC Chairs: P.J. Johnson - Liverpool (United Kingdom), L. Rimassa - Milan (Italy) 16.20 Is it possible to compare the multiple treatments tested for HCC? The Network Metanalysis model A. Cucchetti - Bologna (Italy) 16.40 Is efficacy of Sorafenib and Regorafenib predictable? M. Reig - Barcelona (Spain) 17.00 Stopping rules for Sorafenib in the era of Regorafenib P.J. Johnson - Liverpool (United Kingdom) 17.20 Treatment of HCC in Child-Pugh B class F. Trevisani - Bologna (Italy) 17.40 Discussion 18.00 Round table debate Management of advanced HCC in patients with comorbidities Case presentations F. Tovoli - Bologna (Italy) Expert discussants B. Daniele - Benevento (Italy), M. Reig - Barcelona (Spain), F. Trevisani - Bologna (Italy) 18.30 Closure of the day 4
Saturday, May 19 SESSION 6 A LOOK INTO THE FUTURE OF HCC Chairs: L. Bolondi - Bologna (Italy), J.F. Dufour - Bern (Switzerland) 08.30 The role of Radioembolization M. Seidensticker - München (Germany) 08.50 New molecular targets for systemic therapy J.C. Nault - Paris (France) 09.10 Background and clinical perspectives of immune check-point inhibitors P.R. Galle - Mainz (Germany) 09.30 Postprogression survival and design of second or third line trials in 2018 J. Bruix - Barcelona (Spain) 09.50 Recently concluded and ongoing trials for systemic therapy checkpoint of HCC in 2018: current standpoint L. Bolondi - Bologna (Italy) 10.10 Discussion 10.30 Coffee-break SESSION 7 THE EMERGING ISSUE OF CHOLANGIOCARCINOMA Chairs: P.J. Johnson - Liverpool (United Kingdom), F. Piscaglia - Bologna (Italy) 10.50 Development of HCC and ICC. Molecular pathways with a perspective of clinical relevance J.C. Nault - Paris (France) 11.10 Indications for surgery M. Cescon - Bologna (Italy) 11.50 Treatment of mass-forming non surgical intrahepatic cholangiocarcinoma L. Rimassa - Milan (Italy) 12.10 Locoregional treatment of non surgical obstructive cholangiocarcinoma of the main bile ducts R. Golfieri - Bologna (Italy) 12.30 Discussion 12.50 Closure of the meeting 5
GENERAL INFORMATION MEETING VENUE Aula Magna Nuove Patologie - Pad. 5 S. Orsola Malpighi Hospital - Via Massarenti, 9-40125 Bologna (Italy) The venue is located 10 minutes from Bologna s city centre. It can easily be reached by means of public transportation system. AIRPORT The airport is located 10 km from the city centre. The transfer from the airport to the venue and most of the hotels takes around 30 min by taxi and costs around 20,00; you can also use the airport bus to get to the centre of the town. C.M.E. CREDITS Through the C.M.E. division of the Ministry of Health, this meeting has been registered as part of the Italian credit system for medical studies. Credit certificates shall be issued only if the participant has successfully attended the whole meeting and his/her professional qualifications meet the requirements for entitlement to the study credits in question. The C.M.E. credit certificate will be issued only after the candidate has completed and returned the assessment questionnaire at the end of the meeting. LANGUAGE The official language of the meeting is English. Simultaneous translation will not be provided. LIABILITY AND INSURANCE The organiser is not able to take any responsibility whatsoever for injury or damage involving persons and property during the meeting. Participants are advised to take out their own personal travel and health insurance for their trip. MEETING DOCUMENTS AND BADGES The meeting documents should be collected on-site at the registration desk at the venue. Name badges must be worn at all time during the meeting. CERTIFICATE OF ATTENDANCE The certificate of attendance will be collected from the registration desk during the last day of the meeting. COFFEE BREAKS AND LUNCHES Coffee breaks and lunches are included in the registration fee. REGISTRATION FEE (Registration fees exclude 22% value added tax) ILCA Member: 250,00 ILCA Non-Member: 275,00 Residents and Doctoral Students: 90,00 Please note that ILCA delegates who have not paid their membership dues for 2018 will not be granted the reduced registration fee. To apply for or renew your membership, please visit the membership section on ILCA Website. A copy of student ID card or a Certificate of Resident/PHD Student Status must be provided upon registration. 6
GENERAL INFORMATION ONLINE REGISTRATION You can register to the ILCA School of Liver Cancer 2018 by following the steps on the website: https://www.ilca-online.org/2018-2/ PAYMENT Payment can be made by credit card (Visa, MasterCard or Amex) or by bank transfer. Your registration will be confirmed upon receipt of the full payment only. Cancellation and Refund Policy For more information, please contact: ILCA School of Liver Cancer c/o MCI Benelux S.A. Boulevard du Souverain 280, 1160 Brussels - Belgium Tel: +32 2 7892345 - Fax: +32 2 7431550 info@ilca-online.org HOTEL RESERVATION Please find below a list of suggested hotels all within walking distance from the venue. Please note that ILCA has not blocked any rooms at a preferred rate for these hotels. Therefore, we recommend booking early to ensure availability. Please contact the hotel directly to make your reservation. AEMILIA HOTEL **** Distance from the Congress Venue: 350 m Address: Via Zaccherini Alvisi, 16 - Bologna Website: www.aemiliahotel.it Tel.: +39 051 3940311 E-mail: info@aemiliahotel.it HOTEL BLUMEN *** Distance from the Congress Venue: 750 m Address: Via Mazzini, 45 - Bologna Website: www.hotelblumen.it Tel.:+39 051 344672 E-mail: info@hotelblumen.it HOTEL PEDRINI *** Distance from the Congress Venue: 850 m Address: Str. Maggiore, 79 - Bologna Website: www.hotelpedrini.it Tel.: +39 051 300081 E-mail: www.hotelpedrini.it/contatti/ HOTEL BEST WESTERN SAN DONATO **** Distance from the Congress Venue: 1,3 km Address: Via Zamboni, 16 Bologna Website: www.hotelsandonato.it Tel.: +39 051 235395 E-mail: sandonato.bo@bestwestern.it ART HOTEL COMMERCIANTI **** Distance from the Congress Venue: 1,8 km Address: Via Dè Pignattari, 11 - Bologna Website: www.art-hotel-commercianti.com Tel.: +39 051 7457511 E-mail: commercianti@arthotels.it HOTEL ROMA *** Distance from the Congress Venue: 1,8 km Address: Via Massimo D Azeglio, 9 - Bologna Website: www.hotelroma.biz Tel.: +39 051 231330 E-mail: info@hotelroma.biz Acknowledgement The ILCA School of Liver Cancer 2018 is an initiative organised thanks to an unrestricted educational grant from Bayer HealthCare. 7
Scientific Directors Prof. Luigi Bolondi, Prof. Fabio Piscaglia Unit of Internal Medicine Department of Medical and Surgical Sciences University of Bologna - Alma Mater Studiorum S. Orsola Malpighi Hospital Via Albertoni, 15-40125 Bologna (Italy) luigi.bolondi@unibo.it - fabio.piscaglia@unibo.it Organising Secretariat International Liver Cancer Association (ILCA) Boulevard du souverain, 280 - B-1160 Brussels (Belgium) Tel: +32 2 7892345 - Fax: +32 2 7431550 info@ilca-online.org - www.ilca-online.org Local Secretariat FC EVENTI S.R.L. Vicolo Posterla, 20/2a - 40125 Bologna (Italy) Tel: +39 051 236895 - Fax: +39 051 2916933 info@fc-eventi.com - www.fc-eventi.com