DEPARTMENT OF DEFENSE (AFHSB)

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In NORTHCOM during week 02 DEPARTMENT OF DEFENSE (AFHSB) Seasonal Influenza Surveillance Summary Northern Command -- Week 02 (06 January 2019 12 January 2019) Influenza activity decreased in several states, but continued to remain moderate to high in many states. The percentage of outpatient visits due to ILI decreased during week 02, but remained well above baseline and similar to previous seasons. The percentage of positive lab tests remained stable at 11.5% for service members and increased to 15.8% for other beneficiaries for week 02. Overall, among typed influenza A specimens, influenza A/ H1N1 continued to predominate. However, over the past few weeks, A/H3N2 has predominated in the Midwest. Five influenza hospitalizations (RMEs) were reported for week 02 in Arizona, Florida, Texas, and Virginia (1 service members and 4 other beneficiaries). (Season totals: 6 Service members and 46 other beneficiaries). 2018 2019 NORTHCOM Season Totals A/H1N1 A/H3N2 A/Untyped Flu B AB Overall % Service Members 64 24 360 70 3 5.40 Dependents 367 89 1919 254 54 8.65 Disclaimer: Medical data from Military Treatment Facilities that are using MHS GENESIS are not available in DMSS. This includes Naval Hospital Oak Harbor, Naval Hospital Bremerton, Air Force Medical Services Fairchild, and Madigan Army Medical Center. Therefore, individuals who are expected to seek care at one of these facilities are currently being removed from the study population as we will not capture their medical encounters. 1

In EUCOM during week 02 DoD (AFHSB) Seasonal Influenza Surveillance Summary Influenza activity fluctuated across EUCOM; activity decreased in Germany, Italy, and Greece, while activity increase to high in Turkey. The percentage of outpatient visits continued to decrease, but remained above baseline and similar to previous seasons. The percentage of positive lab tests remained high, but decreased to 17.4% for service members and 27.0% for other beneficiaries for week 02. No influenza hospitalizations (RMEs) was reported for week 02. (Season totals: 1 Service members and 0 other beneficiaries) European Command -- Week 02 2018-2019 EUCOM Season Totals A/H1N1 A/H3N2 A/Untyped Influenza B AB Overall % Service Members 8 6 21 1 1 8.41 Dependents 13 7 52 4 3 10.69 2

DoD (AFHSB) Seasonal Influenza Surveillance Summary In PACOM during week 02 Indo-Pacific Command -- Week 02 Influenza activity remained low in the Republic of Korea and Japan, but was minimal in Hawaii and Guam. The percentage of outpatient visits due to ILI decreased, but remained above baseline and similar to previous seasons. The percentage of positive lab tests remained high, but decreased to 19.4% for service members and 22.4% for other beneficiaries during week 02. Five influenza hospitalizations (RMEs) were reported among other beneficiaries for week 02 (3 in Guam, 1 in Japan, and 1 in the Republic of Korea). (Season totals: 2 Service member and 9 other beneficiaries) PACOM: Guam and Hawaii Influenza Activity and HL7 Test (MAP: SM+BN, 2 wks) Area Name Influenza Activity HL7 Type A(H1) A(H3) A Untyped B AB Guam Minimal 0 3 38 1 3 Hawaii* Minimal 5 0 15 0 0 *Hawaii HL7 Type counts may include samples received from Guam, but tested in Hawaii 2018-2019 PACOM Season Totals A/H1N1 A/H3N2 A/Untyped Flu B Flu AB Overall % Service Members 5 6 142 3 0 14.93 Dependents 14 8 246 14 9 13.82 3

DoD (AFHSB) Seasonal Influenza Surveillance Summary Central and Africa Command -- Week 02 In CENTCOM and AFRICOM during week 02 Influenza activity was minimal in CENTCOM locations with available data, with the exception of Afghanistan, which had high activity. The overall percentage of outpatient visits due to ILI increased and was above baseline and previous seasons. In Afghanistan, influenza activity remained high and the percentage of outpatient visits due to ILI remained stable at 8.6%. In Kuwait, influenza activity remained minimal and the percentage of outpatient visits due to ILI increased slightly to 4.9%. In Djibouti, influenza activity remained minimal and the percentage of outpatient visits due to ILI increased to 9.8%. No influenza hospitalizations (RMEs) were reported for week 02. (Season totals: 0 Service members) In SOUTHCOM during week 02 Southern Command -- Week 02 Influenza activity was minimal in Honduras for week 02. The percentage of outpatient visits due to ILI increased to 7.2% for week 02. Influenza activity remained minimal in Cuba for week 02. The percentage of outpatient visits due to ILI decreased to 1.5% for service members, but increased to 2.1% for other beneficiaries. 2018-2019 Cuba Season Totals A/H1N1 A/H3N2 A/Untyped Flu B Flu AB Total Tested Service Members 0 0 0 0 0 6 Dependents 0 0 1 1 0 11 4

Description: Maps, figures and tables are stratified by Combatant Commands (CCMD). The map provides a measure of influenza activity by state or country within each CCMD for the past two weeks for service members. Influenza activity is defined by the percentage of outpatient visits associated with an Influenza-like Illness (ILI) for each week compared to baseline levels of influenza activity. Additionally, a pie graph by US region or country is generated to display the distribution of influenza types and subtype identified from positive laboratory tests for the past two weeks combined. Influenza activity: Percentage of Outpatient Visits Associated with ILI: The percentage of all outpatient visits for ILI is calculated each week for all service members, regardless of component. These data are presented as a map of the past two weeks activity and a figure to display the entire season s data compared to the two prior seasons and baseline. For the map, the activity level compares the mean reported percent of visits due to ILI for the past two weeks to the mean reported percent of visits due to ILI during baseline weeks. Baseline weeks are defined as non-influenza weeks (weeks 22-39) over the past 3 years. There are four activity levels reported on each map. The activity level corresponds to the number of standard deviations (SD) below, at or above the mean for the current week compared to the mean of the baseline weeks. Activity levels are classified as minimal, low, moderate, and high. Minimal activity corresponds to an influenza percentage that is less than 2 SD above the mean. Low activity corresponds to an influenza percentage that is equal to or greater than 2 SD above the mean, but less than 4 SD above the mean. Moderate activity corresponds to an influenza percentage that is equal to or greater than 4 SD above the mean, but less than 6 SD above the mean. High activity corresponds to an influenza percentage that is equal to or greater than 6 SD above the mean. Influenza Specimens: Lab results from PCR, viral culture, and rapid influenza assays are reported. Although the inclusion of rapid tests may underestimate the weekly and cumulative percent positive estimates due to false negatives, visibility of the positive rapid results provides valuable information for this surveillance report. Influenza types/subtypes are categorized as influenza A not subtyped (A subtype na), influenza A/H1 (A H1), influenza A/H3 (A H3), influenza A and B co-infection (A B), and influenza B (B). Map: Each US region or country with available data contains a pie chart that displays the distribution of influenza types and subtypes for that area for the past two weeks combined. Two weeks of data are combined instead of using just the current week s data due to delays in reporting of laboratory results. Figure and Table: Each week, using the total number of influenza laboratory tests performed and the positive test results, the proportions positive for each serotype of influenza are calculated for service members and dependents separately. Data Sources and Case Definitions: Medical encounter and demographic data from the Armed Forces Health Surveillance Branch s (AFHSB) Defense Medical Surveillance System (DMSS) are used to generate this report. In addition, health-level 7 (HL-7) format laboratory data is provided by the Navy and Marine Corps Public Health Center (NMCPHC) EpiData Center Division. For the past seasons and baseline calculations, ICD-9 codes from outpatient encounters are used to identify influenza activity. The outcome of influenza activity based on ICD-9 codes is defined using the combined codes for ILI (79.99, 382.9, 460, 461.9, 465.8, 465.9, 466.0, 486, 487.0, 487.1, 487.8, 488, 490, 780.6, or 786.2). For the current season, ICD-10 codes from outpatient encounters are used to identify influenza activity. The outcome of influenza activity based on ICD- 10 codes is defined using the combined codes for ILI (B97.89, H66.9, H66.90, H66.91, H66.92, H66.93, J00, J01.9, J01.90, J06.9, J09, J09.X, J09.X1, J09.X2, J09.X3, J09.X9, J10, J10.0, J10.00, J10.01, J10.08, J10.1, J10.2, J10.8, J10.81, J10.82, J10.83, J10.89, J11, J11.0, J11.00, J11.08, J11.1, J11.2, J11.8, J11.81, J11.82, J11.83, J11.89, J12.89, J12.9, J18, J18.1, J18.8, J18.9, J20.9, J40, R05, R50.9). An individual can only be counted as a case once per week. NORTHCOM Regions: The regions on the NORTHCOM map (bold, black outlines) are defined using the four US Census regions, with the exception of Hawaii and Guam which are a part of PACOM. Northeast: Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, Vermont, New Jersey, New York, Pennsylvania, Puerto Rico, and the U.S. Virgin Islands. South: Delaware, the District of Columbia, Maryland, Virginia, West Virginia, Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, Tennessee, Arkansas, Louisiana, Texas., and Oklahoma. Midwest: Illinois, Indiana, Michigan, Minnesota, Ohio, Wisconsin, Iowa, Kansas, Missouri, Nebraska, North Dakota, and South Dakota. West: New Mexico, Colorado, Montana, Utah, Wyoming, Arizona, California, Nevada, Alaska, Idaho, Oregon, and Washington. (All data are preliminary and subject to change as updated data is received) 5