Cath Lab Essentials: Basic Hemodynamics for the Cath Lab and ICU

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Cath Lab Essentials: Basic Hemodynamics for the Cath Lab and ICU Ailin Barseghian El-Farra, MD, FACC Assistant Professor, Interventional Cardiology University of California, Irvine Department of Cardiology

Right Heart Catheterization

By Don Ramey Logan - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=38538349

INDICATIONS Cause of shock Pulmonary hypertension Fluid management and hemodynamic monitoring Guidance for pericardial tamponade Constrictive versus restrictive cardiomyopathy Diagnosis of left to right shunt

CONTRAINDICATIONS ABSOLUTE contraindications: None CAUTION: Pulmonary hypertension Elderly Left bundle branch block

EQUIPMENT

PULMONARY ARTERY CATHETER EXTRA PORT DISTAL PORT PROXIMAL PORT THERMISTOR BALLOON

TECHNIQUE

A Systematic Approach to Hemodynamic Interpretation 1. Establish the zero level and balance transducer. 2. Confirm the scale of the recording. -40 mmhg for RHC, 200 mmhg for LHC 3. Collect hemodynamics in a systematic method using established protocols. 4. Critically assess the pressure waveforms for proper fidelity. 5. Carefully time pressure events with the ECG. 6. Review the tracings for common artifacts

Components of a Right Heart 1.Right atrium Mean (1-5 mmhg) 2.Right ventricle Phasic (25/5 mmhg) Catheterization 3.Pulmonary capillary wedge Mean (7-12 mmhg) 4.Pulmonary artery Pulm HTN: mean PA pressure > 25mmHg PCWP < 15mmhg Phasic and mean (25/10 mmhg; mean 10-20 mmhg)

Precautions Always record pressures at end-expiration During inspiration, pressures will be lower due to decrease in intrathoracic pressure Always zero and reference the system

SAT RUN SVC to RA STEP UP If highest values are used, at least 11% If average of multiple samples, then 7% SVC IVC RA to PA STEP UP highest or average values 5% RIGHT ATRIUM LUNGS RA to RV STEP UP highest values are used, at least 10% If average of multiple samples, then 5% (for L-> R shunt)

1

SIMULTANEOUS RIGHT- and LEFT- HEART CATHETERIZATION 1. Pulmonary artery (PA) catheter to pulmonary artery 2. Measure cardiac output by measuring oxygen saturation in PA and AO blood samples to determine Fick output or by thermodilution (x3); screen for shunt. 3. Record aortic pressures with AO catheter. Cross the AV into the ventricle -> Wedge the PA catheter -> Measure simultaneous LV- PCWP (mitral valve assessment). 4. Pull back from PCWP to PA. 5. Pull back from PA to right ventricle (RV) (to screen for pulmonic stenosis) and record RV. 6. Record simultaneous LV-RV (constriction vs restriction). 7. Pull back from RV to right atrium (RA) (to screen for tricuspid stenosis) and record RA 8. Pull back from LV to AO (to screen for aortic stenosis).

CARDIAC CYCLE

PHASES 1: Atrial Contraction 2: Isovolumic Contraction (TV/MV closure to PV/AV opening) 3: Rapid Ejection 4: Reduced Ejection (PV/AV opening to PV/AV closure) 5: Isovolumic Relaxation (PV/AV closure to TV/MV opening) 6: Rapid Ventricular Filling 7: Reduced Ventricular Filling (TV/MV opening to TV/MV closure)

PRESSURE WAVE INTERPRETATION

LEFT HEART CATHETERIZATION

PITFALLS

ARTIFACTS

CARDIAC OUTPUT

Cardiac Output Thermodilution Fick Method

Thermodilution Bolus injection of saline into the proximal port Change in temperature is measured by thermistor in the distal portion of the catheter

Fick Principle Described in 1870 Assumes rate of O2 consumption is a function of rate of blood flow times the rate of O2 pick up by the RBC Oxygen consumption 1. Direct Fick: -Directly measured 2. Indirect Fick: --3 ml O2/kg X 10

Limitations Thermodilution Not accurate in tricuspid regurgitation Overestimated cardiac output at low output states Fick Oxygen consumption is often estimated by body weight (indirect method) rather than measured directly Large errors possible with small differences in saturations and hemoglobin. Measurements on room air

THANK YOU

Site Right Atrium (or CVP) Normal Pressures Normal Value (mmhg) Mean Pressure (mmhg) 0-5 75% Right Ventricle 25/5 75% Saturation Pulmonary Artery 25/10 10-20 75% PCWP 7-12 95-100% LV 120/10 95-100% Aorta 120/80 95-100%

Normal Values Site Value Sv02 0.60-0.75 Stroke Volume 60-100 ml/beat Stroke Index 33-47 ml/beat/m2 Cardiac Output 4-8 L/min Cardiac Index 2.5-4.0 L/min/m2 SVR PVR 800-1200 dynes sec/-cm5 <250 dynes sec/-cm5 MAP 70-110 mmhg

References Bangalore and Bhatt. Right heart catheterization, coronary angiography and percutaneous coronary intervention. Circulation, 2011; 124: e428-e433. Kern, Morton J. The Cardiac Catheterization Handbook. Philadelphia, PA: Saunders Elsevier, 2011. Print. Ragosta, Michael. Textbook of Clinical Hemodynamics. Philadelphia, PA: Saunders/Elsevier, 2008. Print.