The 2 nd Royal Brompton & Harefield Christmas Postgraduate Course

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The 2 nd Royal Brompton & Harefield Christmas Postgraduate Course The Royal Society of Medicine, 1 Wimpole St, Marylebone, London December 17 th 18 th, 2018 Course Directors Prof. Thomas F. Lüscher, FRCP, FESC Dr. Richard Grocott Mason, FRCP Prof. Kim Fox, FRCP, FESC Scientific Coordination, Organisation Dr. Ruth Amstein, FESC THE YEAR IN CARDIOLOGY REVIEW

Welcome Address Dear Colleagues It is a real pleasure to announce the 2 nd Christmas Postgraduate Course of the Royal Brompton and Harefield NHS Foundation Trust & Imperial College, the Cardiology Update London. Cardiology and cardiovascular medicine in general, is a rapidly expanding field with impressive developments and innovations over the last years. For physicians, be it general practitioners, cardiologists or cardiac surgeons, it is therefore important to keep pace with a challenging environment. To that end, we have designed a postgraduate course, the Cardiology Update London, to summarize, at the end of the year, the most important new developments, innovations, but also failures that will all affect cardiovascular diagnosis and management in our everyday practice. We have selected an international Faculty of renowned experts both from the Trust and worldwide, covering the entire spectrum of cardiovascular medicine from prevention to intervention, from valvular heart disease to heart failure, and from conservative management to intervention and surgical operations. Thus, the course will give an up-to-date overview about current diagnosis and management of the most important cardiovascular conditions. We would be most happy to welcome you at the Royal Society of Medicine in central London to enjoy two days of interactive education for the benefit of your practice and your patients. Yours sincerely, Prof. Thomas F. Lüscher MD, FRPC, FESC Dr. Richard Grocott-Mason MD, FRCP Prof. Kim Fox MD, FRCP, FESC Dr. Ruth Amstein FESC 2

Programme Overview 17 18 Monday, December 17 th Tuesday, December 18 th 08:30 Welcome Address Opening Lectures 08:30 SESSION 4 Valvular Heart Disease TAVI: state of the art Role of imaging Patient selection Percutaneous mitral valve repair 10:00 COFFEE 10:30 COFFEE 10:30 SESSION 1 Risk Factors and Prevention Hypertension Diabetes Lipid management Risk calculation Life-time risk Exercise training Diet Environmental risk 11:00 SESSION 5 Cardiomyopathies and Cardio- Oncology Congenital heart disease 13:00 LUNCH BREAK 12:30 LUNCH BREAK 14:00 SESSION 2 Angina and ACS AMI-STEMI guidelines Medical vs. interventional therapy Myocardial revascularisation DAPT therapy 13:30 SESSION 6 Heart Failure 1 Classification Comorbidities, Treatement of HF (drugs and devices) 16:00 COFFEE 14:45 COFFEE 16:30 SESSION 3 Arrhythmias Atrial fibrillation: medical treatment Ablation Stroke prevention Syncope and SCD 15:15 SESSION 7 Heart Failure 2 Acute and advanced HF VADs Heart transplantation 16:30 The Paul Hamilton Wood Lecture 18:30 NETWORKING RECEPTION 17:00 ADJOURN 3

Scientific Programme Monday, December 17 th, 2018 08:30 09:00 Welcome Address 08:30 The Royal Brompton & Harefield Hospital Trust K. Fox, London T. F. Lüscher, London 08:45 10:15 Opening Lectures: From the Past to the Future Chairs: K. Fox and R. Grocott-Mason, London 08:45 Opening Lecture 1: Clonal Hematopoiesis: A potent newly recognized cardiovascular risk factor 09:15 Opening Lecture 2: Tailor-made decision making on surgical or percutaneous revascularisation based on non-invasive imaging and comorbidities 09:45 Opening Lecture 3: Title tbd P. Libby, Boston P. Serruys, Rotterdam M. Packer, Dallas 10:15 10:45 COFFEE BREAK 10:45 13:00 Session 1: Risk Factors and Prevention Chairs: J. J. Bax and P. Libby 10:45 Hypertension: the new ESC Guidelines M. D. Lobo, London 11:05 Device-based therapies for hypertension F. Mahfoud, Homburg, Saar 11:25 The ESC Guidelines on lipid management: What is valid and what needs to be changed? U. Landmesser, Berlin 11:45 PCSK9 inhibition: From genetics to therapeutics P. G. Steg, Paris 12:05 Diabetes and cardiovascular disease N. Poulter, London 12:25 Discussion 13:00 14:00 LUNCH BUFFET 4

Scientific Programme 14:00 16:00 Session 2: Angina and ACS Chairs: U. Landmesser and P. Serruys 14:00 The best imaging modalities to diagnose CAD J. J. Bax, Leiden 14:20 PCI versus CABG in Stable CAD: Patient selection based on evidence 14:40 Management of ACS today, including ESC Guidelines on myocardial revascularisation 15:00 DAPT or anticoagulation: ESC Guidelines and the new field of thrombocardiology B. Gersh, Rochester S. Windecker, Berne P. G. Steg, Paris 15:20 Non-obstructive CAD, MINOCA A. Lerman, Rochester 15:40 Discussion 16:00 16:30 COFFEE BREAK 16:30 18:00 Session 3: Arrhythmias Chairs: B. Gersh and S. Haldar 16:30 What is new in AF management? Antiarrhythmic drugs and NOACs A. J. Camm, London 16:50 Atrial fibrillation ablation: expanding indications S. Ernst, London 17:10 Towards precision medicine in the prevention of genetically-mediated sudden death 17:30 Diagnosis and management of syncopes: The new ESC Guidelines J. Brugada, Barcelona M. Brignole, Lavagna 17:50 Discussion 18:30 COCKTAIL RECEPTION 5

Scientific Programme Tuesday, December 18 th, 2018 08:30 10:30 Session 4: Valvular Heart Disease Chairs: T. F. Lüscher and S. Windecker 08:30 The role of imaging J. J. Bax, Leiden 08:50 TAVI: current indications and future developments B. Prendergast, London 09:15 An interesting patient with aortic stenosis O. Samara, London 09:30 Mitral valve repair: Surgery or intervention? G. Nickenig, Bonn 09:55 Discussion 10:30 11:00 COFFEE BREAK 11:00 12:30 Session 5: Heart Failure: Classification, Assessment and Treatment Chairs: M. Packer and M. Pfeffer 11:00 Classification of heart failure according to the ESC Guidelines J. Cleland, Glasgow 11:20 A clinical case of heart failure H. O. Savage, Basildon 11:35 The role of biomarkers A. Maisel, San Diego/Basel 11:55 Treatment of heart failure: Drugs and devices M. Cowie, London 12:05 Discussion 12:30 13:30 LUNCH BUFFET 13:30 14:45 Session 6: Heart Failure and Comorbidities Chairs: M. Cowie and A. Maisel 13:30 Diabetes and HF M. Packer, Dallas 13:50 Atrial fibrillation and HF: An evil conspiracy J. Cleland, Glasgow 14:10 Pharmacological management of HFrEF M. Pfeffer, Boston 14:30 Discussion 6

Scientific Programme 14:45 15:15 COFFEE BREAK 15:15 16:30 Session 7: Cancer and Cardiomyopathies Chairs: J. Cleland and P. Kalra 15:15 Cancer patients and HF A. Lyon, London 15:35 Diabetic cardiomyopathy: Are the expectations higher than proof? P. Seferovic, Belgrade 15:55 Hereditary cardiomyopathies and HF S. Prasad, London 16:15 Discussion 16:30 17:00 The Paul Hamilton Wood Lecture Chairs: K. Fox and T. F. Lüscher 16:30 Ventricular remodeling: A personal journey M. Pfeffer, Boston 17:00 Wrap-up and Close T. F. Lüscher, London 7

Teaching Faculty Jeroen J. Bax Leiden, NL Michele Brignole Lavagna, IT Josep Brugada Barcelona, ES A. John Camm John Cleland Glasgow, GB Martin Cowie Sabine Ernst Kim Fox Bernhard Gersh Rochester MN, US Richard Grocott-Mason Shouvik Haldar Paul Kalra Portsmouth, GB Ulf Landmesser Berlin, DE Amir Lerman Rochester MN, US Peter Libby Boston, US Melvin D. Lobo Thomas F. Lüscher / Zurich, CH Alexander Lyon Felix Mahfoud Homburg Saar, DE Alan Maisel San Diego, US / Basel, CH Georg Nickenig Bonn, DE Milton Packer Dallas, US Marc Pfeffer Boston, US Neil Poulter Sanjay Prasad Bernard Prendergast Osama Samara Henry Oluwasefunmi Savage Basildon, GB Petar Seferovic Belgrade, RS Patrick Serruys Rotterdam, NL P. Gabriel Steg Paris, FR Stephan Windecker Berne, CH 8

(tentative and not yet fully confirmed) Sponsors The sponsoring grants are used exclusively for the organisation of the scientific programme. 9

General Information Venue The Royal Society of Medicine, 1 Wimpole St, Marylebone, London W1G 0AE, United Kingdom Registration Registrations can be made exclusively online on our website: www.cardiologyupdate.uk Regular registration fee GBP 300 Early registration fee (until November 23, 2018) GBP 250 Residents, students (age <35) regular fee * GBP 150 Residents, students (age <35) early fee * GBP 100 Day ticket GBP 150 * ID proof required Registration will be confirmed upon receipt of payment. Group Registration For group registrations a minimum of 10 participants is required. Regular registration fee GBP 260 Early registration fee (until November 23, 2018) GBP 210 Please contact Mrs. Nadine-Estelle Kaltheuner (nadine-estelle.kaltheuner@zhh.ch) at the Zurich Heart House to obtain further information. Organisation Zurich Heart House, Foundation for Cardiovascular Research Dr. Ruth Amstein (ruth.amstein@zhh.ch) Nadine-Estelle Kaltheuner (nadine-estelle.kaltheuner@zhh.ch) Hottingerstrasse 14, CH-8091 Zurich, Switzerland Phone +41 (0) 44 250 40 95, Fax +41 (0) 44 250 40 90 www.cardiologyupdate.uk Modification & Cancellation All modifications or cancellations must be notified in writing (by mail, fax or e-mail) to the Zurich Heart House. For each modification requested by the participant, GBP 50 will be charged for administrative costs. In case of cancellation up to 1 st of November 2018, deposits will be refunded less 35 % for administrative costs. After this date, no refund will be possible. 10

General Information Accreditation The Cardiology Update London has been approved by: Federation of the Royal Colleges of Physicians of the United Kingdom for CPD credits 14 category 1 (external) CPD credits EACCME-UEMS European Accreditation Council for Continuing Medical Education (EACCME ) with 13 European CME credits (ECMEC s) Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity. British Cardiovascular Society In collaboration with Under the Auspices of 11