DAILY NEWS BULLETIN LEADING HEALTH, POPULATION AND FAMILY WELFARE STORIES OF THE Day Friday 20180518 MR vaccine When rumour threatens vaccine drive (Hindustan Times:20180518) http://paper.hindustantimes.com/epaper/viewer.aspx Fake alerts spread the rumour that MR vaccine is Modi govt RSS conspiracy to stop the population growth of Muslims A television expose on baseless rumours has been doctored and turned into a fake news clip that has been threatening the health and lives of thousands of children.
ABP News rumour-busting show, Viral Sach: Is there an injection to turn Muslims impotent? has been edited from its original 15.52 minutes to a 2.48- to 3.01-minute clip that propagates the very falsehood it had set out to prove wrong that the globally-banned MR- VAC vaccine against measles and rubella (German measles) was a Modi governmentrss conspiracy to stop the population growth of Muslims. The idea of the show is to expose fake news and if it is being misused to spread rumours, it is wrong. I haven t heard about it but if misuse is happening, we will report the truth again, said Milind Khandekar, managing editor, ABP News. Fake alerts, which included texts, audio and video clips, claiming that the vaccine is unsafe, first surfaced when India launched one of the world s largest vaccination campaigns against measles and rubella on February 5, 2017, in Tamil Nadu, Karnataka, Puducherry, Lakshwadeep and Goa. Within a week, these generic rumours claiming a banned vaccine that affected a child s memory and learning capacity was being pushed in India at the behest of foreign pharma companies, were replaced by rumours targeting the Muslim population. Since then, the clip has been spreading like wildfire ahead of MR vaccination campaigns across India, in states as geographically and culturally diverse as Lakshwadeep, Kerala, Punjab and Manipur. Driven by the fake news, vaccine coverage has been low in states with a high Muslim population: 77.2% in Laskhwadeep (96.58% Muslim poplulation), 84.6% in Kerala (26.56% Muslims), and 87.92% in Manipur (8.32% Muslims), as on May 14. The fake news clip reached Manipur before the vaccines and syringes did. The health ministry s IEC (information, education, communication) materials reached Manipur on March 25, but people started sharing the newsclip in October last year, said Dr T H Nandkishwor, state surveillance officer, Manipur. The clip was made to create trouble and it did. This is the first time we are seeing refusal in the state, there was no trouble during polio vaccination or routine immunisation, said Nandkishwor. A video of the burial of a child falsely claiming it was a vaccine-related death also went viral even though a probe showed the death was unrelated to vaccination. The child died four weeks after vaccination, when anaphylactic shock (extreme allergic reaction) sets in within 30 minutes, but the allegation slowed the programme. Though we have extended the deadline, refusal is high, said Haobam Rosita, deputy commissioner, Thoubal, a district neighbouring Imphal. The state, however, quickly put together an effective response. The resistance to the vaccine in the first round was unexpected but now we re stronger on social media with messages countering the rumours and reinforcing positive messaging from persons trusted in the community. That strategy has helped increase coverage in the second and third rounds, said Dr Yasmin Ali Haque, Unicef Representative in India. Unicef and World Health Organisation are offering technical and surveillance support to the campaign. Working closely with religious and community leaders to build trust, helped. Apart from using radio, television, poster, text messages and social media to urge people to vaccinate, we
had several meetings with community, religious leaders, schools and aganwadi workers in places where there were pockets of refusal, said Dr Nandkishwor. Muslims comprise 93.31% of the population in Lilong town in Thoubal district that has an overall Muslim population of 25.42%. Vaccination coverage in the town went up 15 percentage points over the past two weeks to 78%, because of the tireless efforts of community leaders. Imams made announcements during Friday prayers and madrasas were brought on board. Darul Uloom (Markaz) Haoreibi, a madrasa in Lilong, is home to 463 boys between the ages of nine and 20 years. Only 16 of the 151 boys, aged 15 years and below are yet to be vaccinated. The only children left are those who had gone home from the hostel, I will make sure they get vaccinated, said assistant rector Maulana Mohammad Muheiyuddin Mazahiri. There is reason for his confidence. Along with many others, he also received the doctored video. Everyone had the video, so I went online to read about the vaccine. I found it was safe and made in India. I next met doctors and went to the government store and saw the vaccine to verify whether there were separate vaccines for Hindus and Muslims, as alleged. I found it to be untrue. I even wrote to Darul Uloom Deoband asking whether vaccination should be done and they said yes, it was safe, said Mazahiri. He was convinced, but convincing parents was not easy. People were initially so scared that they made their children miss school on the day vaccination was happening, he said. Mazahiri took a sample of the vaccine and syringe and made short videos showing how it worked, which he sent to religious groups and parents. I told them, you ask a mechanic about cars, a teacher about education, and a doctor about medicine. If you trust doctors for other illnesses, why not for this?, he said. When the imam or maulanas say something, they listen. People hardly listen to us, said N G Jayata, chief medical officer, primary health centre in Kwakta, Bishnupur. Mazahari got support from other community leaders, such as Dr Syed Burhanuddin, chairperson, Manipur State Minorities Commission, who has served in Mecca as a medical officer for 25 years. I tell people that everyone going for Hajj to Mecca and Madina needs to get vaccinated, Saudi Arabia insists on it. People don t get a visa without it. This vaccine is safe and protects our children, we must say yes to it, said Burhan-uddin, who also held a press conference for the local media to spread the message. Medical professionals are doing their bit. Dr Anees Begum, a medical officer in Keirao in Imphal east, got her three children, ages 3, 5 and 7, vaccinated at schools before teachers and students to demonstrate that the vaccine was safe. Staff nurse Ranjana and auxiliary nurse midwife (village health worker) Tasleema from the PHC in Kwakta in Bishnupur visit remote villages to vaccinate missed children on their weekends off. A paramyxovirus virus that spreads through air and direct contact cause measles, with symptoms of high fever that lasts four days to a week, runny nose, cough, watery eyes and
rash. With 47,000 measles deaths, India accounts for close to one-third of the world s 134,200 deaths from the disease, according to the World Health Organisation (WHO). If vaccination coverage is more than 95%, not only are the vaccinated protected but also those who have been missed because mass coverage builds herd immunity in the community by lowering the virus from the environment, said Dr Haque. Vaccination has helped eliminate (absence of continuous transmission for 12 months) measles in the Americas, 33 countries in Europe, and in neighbouring Bhutan and Maldives. With vaccination, India can do it too. Hypertension Hypertension is catching us younger, leading to early onset of ailments: survey (The Hindu:20180518) http://www.thehindu.com/news/cities/delhi/hypertension-is-catching-us-younger-leading-toearly-onset-of-ailments-survey/article23919773.ece Rising obesity in young people is causing lifestyle diseases; 24% of them suffer from or are suspected to show symptoms of blood pressure fluctuations Hypertension [HTN], also known as high blood pressure [HBP], is a long-term medical condition in which blood pressure in the arteries is persistently elevated. HTN is not restricted to a specific gender or age bracket, noted a survey released by Max Healthcare on Rising Juvenile Obesity in the Delhi-NCR. The survey said rising obesity is causing lifestyle diseases, leading to early onset of ailments, and HTN is one of the critical symptoms that children and young adults are suffering from. The survey found that youngsters and children are increasingly suffering from HTN, hormonal issues, blood pressure and blood sugar fluctuations. Twenty-four per cent of obese boys and girls suffer from or are suspected to show symptoms of blood pressure fluctuations. These fluctuations have been commonly observed in 18% of obese boys and girls. Sample size The survey was conducted on a sample size of 1,000 in Delhi-NCR.
Pradeep Chowbey, chairman, Department of Minimal Access, Metabolic and Bariatric Surgery, Max Healthcare, said: Youngsters are sleeping late and often resort to midnight binging. Moreover, increased screen usage time among children these days causes a lot of emotional and hormonal changes. Stress hormones and steroid production is increased in the body, which in turn increases appetite. This in turn contributes to weight gain. WHO says Non-communicable diseases such as cardiovascular diseases, cancer and diabetes have overtaken communicable diseases as the leading causes of mortality in urban areas, said a recent World Health Organization (WHO) report. The report stated that HTN is the third biggest risk factor for heart disease in India and is directly responsible for about 57% of all stroke deaths and 24% of all coronary heart disease deaths in India. The national data stated that 9% women and 14% men falling in the age bracket of 15-49 years suffer from HTN. Lifestyle diseases Arindam Haldar, CEO, SRL Diagnostics, said, Lifestyle diseases like HTN can be prevented by shifting to a preventive healthcare mindset. The fact is that it is far more affordable to prevent a disease rather than cure it. And as is the case with most lifestyle diseases like HTN, once a person is diagnosed with one, he or she has to manage it for the rest of his/ her life. Regular check-ups He added that it is far more easier for a person to get regular check-ups done by a qualified physician and at a laboratory, and follow advice on lifestyle changes that may need to be made to live a long and healthy life. Lung Cancer Why is lung cancer so difficult to treat? (Medical News Today:20180518) https://www.medicalnewstoday.com/articles/321817.php Lung cancer is one of the most common in the United States and treating it is incredibly challenging. A new study investigates how the immune response to tumor cells may be tweaked to improve survival rates.
Doctor looking at lung X-ray A new study delves into the immune response to lung cancer. Affecting both men and women, lung cancer accounts for around 14 percent of all new cancer diagnoses. The American Cancer Society (ACS) estimated that, in 2018, there will be more than 234,000 new cases of lung cancer and over 154,000 deaths to it. Each year, more people die from lung cancer than they do from breast, prostate, and colon cancer combined. One reason that the prognosis for lung cancer is so poor is that only around 20 percent of cases respond to immunotherapies. This is significantly lower than other cancers. Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) in Germany are trying to work out what it is about lung cancer that makes immune-based treatments so hit and miss. Lung cancer and immunity Lead researcher Dr. Susetta Finotto, the head of the Department of Molecular Pneumology at FAU, puts it simply. "Sometimes the body's immune system responds to lung cancer but sometimes it fails, letting the cancer take over." Finding out why this is the case is proving to be challenging, and Dr. Finotto has already published a number of papers on the topic. Her latest research was published this month in the journal OncoImmunology. Is it lung cancer? This blood test can tell A new blood test may be able to distinguish between malign and benign tumors. A successful immune response to a cancer cell depends on a huge number of signaling molecules working in synchrony. One important component of the response is a transcription factor called Tbet. This protein encourages the production of other cells that are important in the fight against tumors, including group 1 T helper cells (Th1 cells) and CD8 T cells. During Dr. Finotto's earlier research, she discovered that lung tumors tend to grow back if there is no Tbet present in the immune cells, underlining Tbet's importance. For the next phase of her research, she joined forces with Drs. Denis Trufa and Horias Sirbu, both from the Department of Thoracic Surgery at FAU. This time, the focus was on another important immune modulator, known as Treg. The importance of Treg
Although Treg is known to help reduce inflammation in the lungs, little is known about the part that it plays in lung carcinoma. However, earlier research has shown that Treg cells reduce the anti-tumor response in lung cells, thereby promoting tumor growth. Dr. Finotto and her team found that lung tumors are able to "reprogram" the immune response to a tumor; they modulate the response by producing TGF-beta, a protein with a range of roles that includes the promotion of Treg cells. This has the effect of rolling back the immune attack on cancer cells. "Precisely those Th1 cells with Tbet that are responsible for anti-tumor immune defense are the ones that are switched off," as Dr. Finotto explains. "This newly identified TGF betadependent mechanism in lung cancer is very important for the regulation of tumor growth in the lung and offers new approaches for lung cancer therapy." The researchers hope that by intervening in this immune pathway, lung cancer patients' survival rates might be improved. They believe that by giving patients drugs that inhibit TGF alongside conventional immunotherapy, they might remove the Treg cell blockade that halts the immune response to the growing tumor. The immune system's interactions with cancer are complex and these discoveries are fairly recent, so it will be some time before human patients see the benefits of this new insight. Bipolar Could these 'molecular switches' stop brain cancer? (Medical News Today:20180518) https://www.medicalnewstoday.com/articles/321838.php It might be possible to change the course of glioblastoma, a very aggressive brain cancer, by manipulating small molecules that switch genes on and off inside cells. By manipulating mirnas, we may be better able to treat glioblastoma, a highly aggressive type of brain cancer. This was the conclusion of a study in which researchers in the United Kingdom and India manipulated gene-regulating molecules known as micrornas (mirnas) in "human glioblastoma cells."
In a paper published in the journal Scientific Reports, they report how "overexpression" of two particular mirnas reduced the ability of the brain cancer cells to invade and multiply. The findings strengthen the case for using molecular techniques to slow or reverse the progress of glioblastoma a "devastating disease" with few treatment options says cosenior study author Dr. Arijit Mukhopadhyay, who researches and lectures in human genetics at the University of Salford in the U.K. "We observed," he adds, "significant reduction of proliferation and invasion capacity and increased apoptosis [programmed cell death] of cancer cells when we used increased expression of micrornas as a switch." Glioblastomas are difficult to treat Glioblastoma is an aggressive cancer that starts in cells known as astrocytes. These form the tissue that supports the neurons that carry and process information in the brain and spinal cord. The main reason that the cancer is so aggressive is because astrocytes "reproduce quickly" and the tissue has a rich blood supply. Around 15.4 percent of "all primary brain tumors" are glioblastomas. Management of glioblastoma, which has "remained stable" for 40 years, usually consists of surgery with radiation and chemotherapy. But, the tumors can be very difficult to remove with surgery because they have long "tentacles" that can reach into other parts of the brain. There is hope, however, that recent progress in genetic and molecular techniques will improve the "management and outcome of this devastating tumor." mirnas have a role in cancer mirnas are small non-coding molecules inside cells that can alter the expression of specific genes. This means, for example, that if the affected gene is one that codes for a protein, a mirna that silences the gene could stop the cell from making the protein. The study of mirnas is a relatively "new and exciting field" with "profound implications" for medicine. Brain tumor: New inhibitor may fight glioblastoma expansion The discovery of a stem cell mechanism that allows glioblastoma to proliferate has led to a new drug aimed at halting the cancer. Although there is still a lot to learn about their specific targets and mechanisms of action, we know that mirnas regulate many genes that control a great number of cell processes and pathways.
Since the first mirna was discovered 30 years ago in roundworms, researchers have identified more than 2,000 in humans and it is thought that they control around a third of "protein-coding genes" in the human genome. Studies show that mirnas have altered "expression profiles" in particular tumors, which suggests that they have a role in cancer. It has also been demonstrated that mirnas are likely to be involved in the development of colon cancer through interaction with gut bacteria. 'New candidates for disease management' In the new study, Dr. Mukhopadhyay and his colleagues investigated a "cluster" of mirnas that previous work had found to be more weakly expressed in human glioblastoma. Using a technique called "real-time polymerase chain reaction," they tested the effect of mirna expression in tumor samples taken from patient biopsies. They found that they could manipulate two mirnas called mir-134 and mir-485-5p like "molecular switches" to make the cancer cells act more like normal cells. They note, "Overexpression of mir-134 and mir-485-5p in human glioblastoma cells suppressed invasion and proliferation, respectively." The authors conclude that the two molecules may have "therapeutic value" that progresses the field "toward better disease management and therapy." "Adult brain cancers, especially glioblastoma [are] very aggressive with very limited management options. This research opens up newer approaches and candidates for disease management and therapy." Dr. Arijit Mukhopadhyay Women Health Can estrogen levels affect weight gain? (Medical News Today:20180518) https://www.medicalnewstoday.com/articles/321837.php Menopause Causes of imbalances What is estrogen? Symptoms of low estrogen Managing weight gain Outlook
Many women report that changing estrogen levels affect their weight, particularly around menopause. They may notice that they are gaining weight, or that it is more difficult to lose weight. Some forms of estrogen are linked with how the body controls weight gain. As such, any changes in their levels could then lead to changes in body weight. So, what is the relationship between a woman's estrogen levels and her weight? Read on for more information about this phenomenon and what to do about estrogen-related weight gain. Menopause, estrogen, and weight Mature woman outside looking contemplative considering estrogen and weight gain Menopause causes a drop in estrogen levels. Estrogen levels can be low in women for many reasons. The most common reason for low estrogen is menopause. This is when a woman's reproductive hormones decline, and menstruation stops. Many women notice that they gain weight during this time in their life. One reason why people might gain weight around menopause is changing hormone levels. One form of estrogen called estradiol decreases at menopause. This hormone helps to regulate metabolism and body weight. Lower levels of estradiol may lead to weight gain. Throughout their life, women may notice weight gain around their hips and thighs. However, after menopause, women tend to gain weight around their mid-section and abdomen. This type of fat gain tends to build up in the abdomen and around the organs, where it is known as visceral fat. Visceral fat can be very dangerous. It has been linked with several other medical conditions, including: diabetes stroke heart disease some cancers As well as changing estrogen levels, older women may tend to be less active and have less muscle mass, which means that they burn fewer calories during the day. These factors can all increase a woman's risk for weight gain during the transition to menopause.
These age-related factors may play a more significant role in weight gain than changes to estrogen levels. In line with this, one review of studies from 2012 concluded that weight gain did not appear to be affected by hormone changes related to menopause. Other reasons for estrogen imbalance Menopause is not the only reason why a woman might have low estrogen levels. Other potential causes of estrogen imbalance include: Polycystic ovary syndrome (PCOS) WOman with PCOS clutching stomach in pain. PCOS causes cysts on the ovaries and may affect hormone levels. PCOS is a condition where a woman has multiple small cysts on the ovaries, as well as several hormonal imbalances. They may have high testosterone levels and an imbalance between estrogen and progesterone levels. Women with this condition tend to have an issue with weight gain, insulin resistance, and heart disease. Lactation Estrogen levels remain low after a woman has given birth and while she is breast-feeding. This hormonal change helps to encourage milk production and prevent ovulation and any further conception right away. Ovary removal A woman who has had both of her ovaries surgically removed will go through sudden menopause. She will no longer release eggs or produce estrogen and progesterone. Anorexia Anorexia is a serious eating disorder where someone does not take in enough calories. This deficit puts their body in a state of starvation and will reduce the amount of estrogen their body produces. Vigorous exercise Vigorous or extreme exercise has been shown to decrease estrogen production due to low body fat levels. What is estrogen? Estrogen is one of the two primary female sex hormones and is involved in the onset of puberty and the menstrual cycle. It has many other essential functions, as well, including:
helping to control blood cholesterol levels promoting bone health protecting the brain and mood The ovaries, which are two small glands in the lower pelvis, are mainly responsible for the production of estrogen. The adrenal glands and fatty tissue also make estrogen in small amounts. There are three main types of estrogen: Estrone, or E1, which the body produces after menopause. Estradiol or E2, which women of childbearing age produce. Estriol or E3, which the body produces during pregnancy. Symptoms of low estrogen Woman with insomnia Low estrogen levels may cause insomnia and night sweats. Symptoms of low estrogen include: irregular or missed periods hot flashes night sweats insomnia vaginal dryness low libido moodiness or irritability headaches dry skin Women experiencing any of these symptoms should talk to a doctor about them. A doctor can run a simple blood test to measure estrogen levels and determine if an estrogen imbalance is to blame. Women should keep track of their menstrual periods, including when they begin and end, and any other symptoms or problems that they are experiencing. Having this information readily available can help a doctor diagnose potential hormonal imbalances.
What happens when estrogen levels are low? Learn more about the effects of low estrogen levels on the body. This article looks at the signs, symptoms, and treatment options when needed. How to manage weight gain Maintaining a healthy weight, even if it is related to an estrogen imbalance, begins with eating well and staying active. A healthful diet to manage weight means: avoiding processed foods eating lots of fruits and vegetables each day staying hydrated by drinking lots of water avoiding soda, juice, and alcohol including whole grains and lean proteins along with healthful plant-based fats Being active is also very important for managing estrogen-related weight gain. In addition to regular cardio exercise, such as jogging, swimming, or walking, people should add in strength training to help build muscle and promote healthy bones. Outlook Weight gain is a common complaint among women who reach menopause. Making healthful diet and lifestyle changes are the best way to manage weight gain. People should talk to their doctor about any concerns that they may have related to weight gain or hormone imbalances.
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फ इबर कई è ȡj Ȳस बच ए फ इबर (Hindustan:20180518) http://epaper.livehindustan.com/textview_111_50412092_4 15_18-05-2018_1_0.html फ इबर ȧकम प ट ȧकई ɉ ȧवजह ह भ जन पच न और ] Ȳ ɉ ȧसफ ई रखन Ʌभ ^ ȧख स Ǘ ȡह त ह, पर è ȡयह ह Ï ȡ ȡ क आह र Ʌ Ǿ क Ǖ ȡǒ फ इबर ह त ȣ ȣȳ @. ȣ Ʌफ इबर ȧ कम स कई ȯ ȡǓ ȡȲह सकत ɇ@ Þ, Ǖè प चन व वजन बढ़न ज स è ȡj Ȳक प छ एक क रण फ इबर ȧ कम भ ह आमत र पर Ǒ ȡj Ȳक हर र ज 25 Ē ȡ फ इबर ȧ सल ह ȣ ज त ह Ǖǽ ɉ क इसस \ ȧ Ǿ ह त ह फ इबर Ȫ ȯèěȩ और È [ ȡ ȧ ȡğȡक भ Ȥ रखत ह भ जन ȡस भ जन क ] Ȳ ɉतक ल ज न और ȣ स ब क र ɉक ब हर Ǔ ȡ ȯ Ʌ^ ȧख स Ǘ ȡह त ह ȡ^ ǕÈ Ȣ ɉक Ǔ स वन आ त, छ त व ȡ[ क ɇ ȧआश क क भ कम करत ह बव स र Ʌभ यह ȡ ȡ ȣ ह इसस ǿ र ग व èěȫ ȧआश क कम ह त ह. द तरह क फ इबर. घल नश ल और अघल नश ल द तरह क फ इबर ह त ɇ@घल नश ल फ इबर ȡ ȣ Ȣ Ʌ\ प न स ख कर ग ढ़ तरल क Ǿ ल ल त ɇ@य फ इबर प ट Ʌ [ ȡ, Ȫ ȯèěȩ व वस क अपन स थ ल त ह ए प चन- Ȳ ğ Ʌन च ल त ɇ@^û Ʌपचन Ʌ\ समय लगत ह, ^ f द र तक प ट भर महस स ह त ह अघ लनश ल फ इबर क İ Ȫ प न कम स खत ɇऔर पचत ȣȳ ɇ@य ] Ȳ ɉ Ʌम ज द \ ç क न च ल ज त ह ए ` Û Ʌ ȣ स ब हर करन Ʌसह यत करत ɇ@ Ȫ ɉ ȣतरह क फ इबर हम र ȣ क f Ǿ ȣह त ɇ@. घ लनश ल फ इबर: कई तरह क ब स (र जम, Ȫǒ ȡ) ȣ, j ɪ (जई ȧभ स, जई क ȡ), Ï ȡ, ब जर, र ग, ज, स य ब न, अलस, ईसबग ल और फल ज स स ब, न शप त, èěȩ ȯ ȣव \ Û ȯ ɉ Ʌय फ इबर भरप र ह त ह.
अघ लनश ल फ इबर: ^ Ʌस ब त अन ज, Ħ ȡ` र इस, मस र ȧद ल, ȡ, È ȡ ȧभ स, ȣ स म ȧ ȡȲ, ब द ग भ, ȣ ȯ ȡ ǔþ ȡȲ, ग जर, Ħ Ȫ ȣ, मटर, शलगम, ȲȢ, फल व ǔþ ɉक Ǔ ȯ ȡ ह त ɇ@ Diet/Nutrition (Dainik Jagran:20180518) http://epaper.jagran.com/epaperarticle/18-may-2018-edition-delhi-city-page_15-758-55744.html
Healthcare (Navbharat Times:20180518) http://epaper.navbharattimes.com/details/74507-68080-1.html