This SOP applies to all staff employed by NHS Greater Glasgow & Clyde and locum staff on fixed term contracts and volunteer staff.

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Page 1 of 9 Review SOP Objective To ensure that Healthcare Workers (HCWs) are aware of the actions and precautions necessary to minimise the risk of outbreaks and the importance of diagnosing patients clinical conditions promptly. This SOP applies to all staff employed by NHS Greater Glasgow & Clyde and locum staff on fixed term contracts and volunteer staff. KEY CHANGES FROM THE PREVIOUS VERSION OF THIS SOP Updated wording in Section 1. Responsibilities, Updated wording in Section 2. General Information on Measles Updated wording in Section 3. Transmission Based precautions for Patients with Measles Updated references in Section 4. Evidence Base Document Control Summary Approved by and date Board Infection Control Committee 23 rd Date of Publication 23 rd Developed by Related Documents Distribution/Availability Implications of Race Equality and other diversity duties for this document Lead Manager Responsible Director Infection Control Policy/SOP Sub-Group National IPC Manual NHSGGC Hand Hygiene Policy NHSGGC Laundry Policy NHSGGC SOP Occupational Related Illnesses NHSGGC SOP Cleaning of Near Patient Equipment NHSGGC SOP Twice Daily Clean of Isolation Rooms NHSGGC SOP Terminal Clean of Isolation Rooms NHSGGC SOP Terminal Clean of Ward NHSGGC SOP Last Offices NHSGGC Infection Prevention and Control Policy Manual and www.nhsggc.org.uk/your-health/publichealth/infection-prevention-and-control/ This SOP must be implemented fairly and without prejudice whether on the grounds of race, gender, sexual orientation or religion. Board Infection Control Manager Board Medical Director

Page 2 of 9 Review CONTENTS 1. Responsibilities... 3 2. General information on Measles... 4 3. Transmission Based Precautions for patients with Measles... 6 4. Evidence Base... 9

Page 3 of 9 Review 1. Responsibilities Healthcare Workers (HCWs) must: Follow this SOP. Inform their line manager if this SOP cannot be followed. Clinicians must: Notify NHSGGC Public Health Protection Unit (PHPU) if they diagnose a clinical case of Measles. Microbiologists must: Laboratory staff must notify NHSGGC PHPU if they make a laboratory diagnosis of Measles. Senior Charge Nurses (SCN) / Managers must: Support HCWs and Infection Control Teams (ICTs) in following this SOP. Advise HCWs to contact the Occupational Health Service (OHS) as necessary. Infection Prevention and Control Teams (IPCTs) must: Keep this SOP up-to-date. Provide education opportunities on this SOP. OHS must: Advise HCW regarding immune status, possible infection exposure and return to work issues as necessary.

Page 4 of 9 Review 2. General information on Measles Communicable Disease/ Measles caused by the measles virus an enveloped virus. Alert Organism Clinical Condition A respiratory disease caused by the measles virus. It is an acute disease which causes fever, cough, coryza, conjunctivitis, diarrhoea, erythaematous maculopapular rash and spots (Koplik spots) on the buccal mucosa and is highly infectious. The spots usually appear before the rash. Incubation period Mode of Spread Symptoms first appear 10-12 days after exposure to the virus. Usually symptoms start as fever, then runny nose, cough and/ or conjunctivitis (pink eye). A rash appears starting from the face and neck, any time between day 3 and day 7 after symptoms start. Within 3 days the rash then spreads downwards and out to the hands and feet. It lasts about 4-7 days. The disease can be more severe in infants and adults than children with as many as 20% having complications, especially in those < 5 and > 20 years of age. Complications include otitis media, viral pneumonia, croup, rarely encephalitis and (later) subacute sclerosing panencephalitis. Secondary bacterial infections, such as pneumonia, can also occur. Infections can be life-threatening in the immunosuppressed. If a clinical case of measles is suspected, clinicians should seek advice from a paediatric/ adult ID physician. 7 18 days. Airborne and Droplet transmission The virus can be inhaled directly into the airways. Droplets are dispersed in the air when the patient coughs, sneezes or talks. Droplets from an infected person may land on the mucous membranes of the eyes, nose or mouth of a susceptible person. Direct contact hands touching a contaminated surface then touching the mucous membranes of the eyes, nose or mouth of a susceptible person. Indirect contact a contaminated object having contact with the mucous membranes. The virus can survive on inanimate surfaces for several hours and can be transmitted via the hands from these

Page 5 of 9 Review Notifiable disease Period of communicability contaminated surfaces. Yes. Cases should be notified by medical staff to: PHPU, Consultant in Public Health Medicine (CPHM) via switchboard - Gartnavel Royal Hospital, West House, 1055 Great Western Road, Glasgow, G12 0XH. Five days before the onset of the rash until 4 days after. Immunocompromised patients may have prolonged excretion of the virus in respiratory secretions and can be infectious for the duration of the illness. Patients with subacute sclerosing panencephalitis (SSPE) are not infectious. Persons most at risk Anyone who has not had measles or 2 doses of MMR vaccination, including children less than 12 months old. The risk of complications resulting from measles is high among infants younger than 1 year of age. Therefore consideration should be given to vaccination of infants as young as 6 months if given within 72 hours of exposure. Immunocompromised patients and pregnant woman, exposed to Measles, should also be reviewed to determine level of exposure and immunity. Staff, who have been exposed and are uncertain of their immunity status, should speak to occupational Health and/or their own GP if concerned.

Page 6 of 9 Review 3. Transmission Based Precautions for patients with Measles Accommodation Patients must be nursed in a single room, preferably with en (Patient Placement) suite facilities and negative pressure ventilation until 4 days after the onset of the rash. Clinical / Healthcare Waste Contacts Crockery / Cutlery Only staff who have previously had measles or who have demonstrated immunity should care for patients with measles. Staff, who have been exposed and are unsure of their immunity status, should contact Occupational Health and/or their own GP. All non-sharps waste from patients with Measles should be designated as clinical healthcare waste and placed in an orange bag. See NHS GGC Waste Management Policy There is no specific treatment for measles. Human immunoglobulin can be used to prevent or reduce the severity of measles and is most effective if given within 72 hours. No special precautions. Domestic Services / Facilities Equipment Exposure (staff) Only staff who have had measles or who have demonstrated immunity to measles should enter the room to provide domestic services. Staff, who have been exposed and are unsure of their own immunity status, should contact Occupational Health and/or their own GP. Please refer to NHSGGC SOP Twice Daily Clean of Isolation Rooms: Take only into the room that which is necessary. Where possible, patient equipment should be allocated to the patient for as long as they remain infectious. Dedicated equipment must be kept clean using a chlorine based detergent and then dried thoroughly Please refer to NHSGGC Decontamination SOP. Prevent exposure by allowing only HCWs who are immune to measles to care for patients during the infectious period using Standard Precautions and Transmission Based Precautions. Refer to NHSGGC Occupational Related Illnesses SOP Pregnant staff or staff who have been exposed and are unsure of their immunity status should contact Occupational Health and/or their own GP for advice as soon as possible.

Page 7 of 9 Review Exposure (patients) Hand Hygiene Last Offices Linen Seek advice from an Infection Specialist. Contact Gartnavel General Hospital or the on-call consultant in paediatric infectious diseases at Yorkhill Hospitalvia switchboard. Children less than 12 months old, immunocompromised patients and pregnant contacts should be assessed for administration of post exposure prophylaxis (PEP) with human normal immunoglobulin (HNIG) http://www.hpa.org.uk/webc/hpawebfile/hpaweb_c/12385 65307587 Measles can be transmitted by contact touching. Hands must be decontaminated before and after each direct patient contact, after contact with the environment, after exposure to body fluids, e.g. respiratory droplets, and before any aseptic tasks. Patients should be encouraged to carry out thorough hand hygiene. Please refer to NHSGGC Hand Hygiene Policy See Standard Operating Procedure for Last Offices. Discard linen as fouled/ infected, i.e. in a alginate bag then a clear bag tied and then into a laundry bag. Please refer to NHSGGC Laundry Policy Marking Notes Moving between wards, hospitals and departments (including theatres) Notice for Door Outbreak Not required. Patient movement should be kept to a minimum. Prior to transfer HCWs from the ward where the patient is located must inform the receiving ward, theatre or department of the patient s infectious condition. When patients need to attend other departments the receiving area should put in place arrangements to minimise contact with other patients and arrange for additional domestic cleaning if required. Yes. Outbreaks in hospitals are not likely due to herd immunity. Community outbreaks are sporadic. In the rare event that an outbreak is suspected, contact a member of the IPCT/on-call

Page 8 of 9 Review Microbiologist for advice. Personal Protective Equipment (PPE) To prevent spread of this virus through direct contact PPE (disposable gloves and aprons) must be worn for all direct contact with the patient or the patient s environment/ equipment during the infectious period. If there is a risk of splashing/spraying blood or body fluid wear surgical face mask. If staff undertake and Aerosol Generating Procedure a fit tested FFP3 mask is recommended Precautions required until Screening on Admission Screening staff Transmission Based Precautions are required until 4 days after the onset of the rash. All patients should be assessed for infectious diseases on admission. If a patient presents with an unexplained rash, TBPs should be implemented until infection is ruled out. Because of the 7-18 day incubation period, there is no reason for immediate absence from work. Pregnant staff or staff who have been exposed and are unsure about their immune status should contact OHS or their GP for advice as soon as possible Specimens required Specimens Mark as Danger of Infection Terminal Cleaning of Room Visitors Throat swab in viral meduim Not required. See SOP Terminal Cleaning of Isolation Rooms. Clinical staff should explain the risk of Measles exposure to visitors. A history of measles or 2 doses of MMR immunisation is considered evidence of immunity. Close contacts of the patient who are not immune could potentially be incubating the infection and should be advised against visiting. Contact the IPCT for advice.

Page 9 of 9 Review 4. Evidence Base Health Protection Agency (2014) Guidelines on Measles https://www.gov.uk/government/collections/measles-guidance-data-and-analysis Health Protection Network: Guideline for the Control of Measles Incidents and Outbreaks in Scotland (2014) http://www.documents.hps.scot.nhs.uk/about-hps/hpn/measles-guidelines.pdf American Academy of Paediatrics. 2009 Red Book: Report of the Committee on Infectious Diseases, 27th. Ed. Immunisation against infectious disease Green Book (2013). Department of Health. http://immunisation.dh.gov.uk/green-book-chapters/chapter-21/