Category Term Definition Comments 1 Major Categories 1a

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Working Lexicon Categories, Terms & Definitions Category Term Definition Comments 1 Major Categories 1a Physiologic Category (consistent with normal ovarian physiology) Follicle Simple 3 cm in premenopausal group Corpus luteum (CL) Thick walled 3 cm that may have crenulated inner margins, internal echoes and intense peripheral color Doppler flow. CL can sometimes appear as a hypoechoic region in the ovary with peripheral vascularity without a characteristic ic. 1b Unilocular, no solid Unilocular with solid (s) Multilocular, no solid elements Multilocular with solid (s) Solid (greater than or equal to 80% Lesion Category (not consistent with normal physiology) Cystic lesion that contains a single compartment. May contain 1 incomplete septum, wall irregularity < 3mm height or internal echoes. As above but includes solid (s) 3mm in Cystic lesion with more than one compartment (at least one complete septum) but no solid (s) 3mm in As above but includes 1 solid (s) 3 mm in Lesion with echogenicity suggestive of tissue without characteristics of a. Lesion is at least 80% solid when assessed in orthogonal 2-dimensional planes. 2 Size Maximum diameter Maximum diameter of a lesion in any plane. Simple is a subset of unilocular with a smooth, thin wall, acoustic enhancement and no internal elements Purely solid (100%) is a subset of a solid lesion consisting of a lesion with no ic. Maximum diameters Maximum diameter of the largest solid Largest 3 diameters in 2 perpendicular planes. One of these will be the maximum diameter of the lesion. Maximum diameter of the largest solid in any plane. An optional volume may be obtained from these diameters. 3 Solid or Solid-Appearing Lesions 3a External contour Smooth Regular outer margin 1

3b Irregular (Not Smooth) Hypoechoic/ isoechoic/ hyperechoic Calcification(s) Non-uniform outer margin Internal contents Decreased/similar/increased echogenicity when compared to the internal reference of normal ovarian stroma. High-level echogenic with associated acoustic shadowing within the solid appearing portion of the lesion. Acoustic shadowing Artifact produced by attenuated echoes behind a sound absorbing structure. 4 Cystic Lesions 4a Inner Margin or Walls Smooth Regular, uniform inner margin Irregular (not smooth) Irregular, non-uniform inner margin. May include wall irregularities due to incomplete septations, solid s < 3mm height or papillary projections (solid s 3mm in height) 4b Endometrioma Descriptor Dermoid Calcification(s) High-level echogenicity within wall which is curvilinear or plaque-like and may demonstrate associated acoustic shadowing A lobulated outer margin is considered irregular. Hypoechoic solid lesions typically represent fibromas or pedunculated/broad ligament fibroids. Descriptor is commonly associated with calcification(s) or fibromatous type lesion. Internal Content, Cystic Component Anechoic fluid No internal echoes or structures of any kind Using appropriate technical gain settings Hyperechoic s Area of increased echogenicity with respect to normal ovarian parenchyma without acoustic shadowing Descriptor associated with dermoid or hemorrhagic lesions Scattered low-level echoes Scattered or heterogeneously dispersed echoes within a Descriptor typical of mucinous material within a Fluid/fluid level Nondependent portion that is relatively hypoechoic with respect to the dependent portion with horizontal delineation Typically related to evolving blood clots with supernatant relatively hypoechoic to the contracted clot material Ground glass or homogeneous lowlevel echoes Echogenic with acoustic shadowing Nondependent portion that is relatively echogenic to the dependent portion with horizontal delineation Homogeneously evenly dispersed echoes within a Attenuation of the acoustic beam distal to a hyperechoic Fat-fluid level with the nondependent fat containing material that appears relatively echogenic 2

Hemorrhagic descriptors Hyperechoic lines and dots Floating echogenic spherical structures Reticular pattern Bright linear echoes and foci representing linear echoes seen en face Non-dependent echogenic spheres that may be associated with posterior acoustic shadowing and have been called dermoid balls Fine thin intersecting lines representing fibrin strands that should not be confused with septations Represents sections through hair within the liquefied. Descriptor highly characteristic of dermoid lesion, albeit uncommon Retractile clot Avascular echogenic with angular, straight, or concave margins Septations Complete Strand of tissue extending across the cavity from one internal wall to another in all scanning planes Incomplete Strand tissue not completely extending from one internal wall to another in all planes 4c Solid or Solid/Appearing Component Papillary projection or nodule Solid whose height 3 mm, arises from the wall or septation and protrudes into the cavity. Number of papillary projections should be included Outer contour Smooth The contour of the solid within a demonstrates no irregularities Irregular (not smooth) The contour of the solid or of any internal ic area within the solid demonstrates irregularities 5 Vascularity Circumferential color Color Doppler flow is restricted to the wall and includes Descriptor typically associated with corpus luteum Doppler Wall Flow Internal Color Doppler flow Color score 1-4 the majority of the circumference of the wall Color Doppler flow is detected internally within a solid /mural nodule or in a septation of the lesion with or without peripheral (wall) flow. Overall subjective assessment of color Doppler flow within the entire lesion (wall and/or internal ) Color Score = 1=No flow Color Score = 2 = Minimal Flow Color Score = 3 = Moderate flow Color Score = 4 = Very Strong Flow 6 General and Extra-Ovarian Findings IOTA Group criteria 2 3

Cysts Fallopian Tube (abnormal) Fluid Peritoneal inclusion Paraovarian Incomplete Septation Tubular Endosalpingeal folds Cul-de-sac fluid Cyst with no mass effect conforming to contours of pelvic structures, typically contains fine septations. The ovary is either at the margin or suspended within the lesion. Simple exists separate from ovary and moves independent of the ovary Non-continuous tissue is seen extending across the ic cavity due to the wall of the distended fallopian tube folded upon itself Substantially longer in one dimension than in the two perpendicular dimensions. Short round projections around the inner wall of a fluid distended tubular structure Confined to pouch of Douglas as defined by remaining below uterine fundus or between uterus and bladder when uterus retroverted/retroflexed Alternate term para-tubal Other Ascites Anechoic Fluid containing internal echoes Peritoneal thickening or nodules Fluid extending above uterine fundus beyond the pouch of Douglas or cul-de-sac when anteverted/anteflexed, and anterior/superior to uterus when retroverted/retroflexed Simple fluid Not simple fluid Nodularity or diffuse thickening of the peritoneal lining(s) or along the bowel serosal surface or peritoneum associated with peritoneal carcinomatosis Adenopathy Lymph nodes measured in short axis 4

5