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CURRICULUM VITAE (SUMMARY) Full Name: Lino Manuel Martins Gonçalves Birthdate: September 23, 1960 Loulé (Portugal) Civil State: Married Nationality: Portuguese Current Address: Rua Carlos Oliveira, 17, 3030-391 Coimbra, Portugal Cellular Telephone: + 351239 800 005 E-mail: dir.cardiologia@chc.min-saude.pt Education and Experience: High School: Medical School: Graduate School: Postgraduate Training: General Internship: Cardiology Fellowship: Visiting Associate: Loulé High School, Loulé, Portugal (1973-1978). University of Coimbra Medical School, Coimbra, Portugal (1978-1984) Degree: M.D., 1984. University of Coimbra Biology School, Coimbra, Portugal. Degree: Master in Cellular Biology, 1994. University of Coimbra Medical School, Coimbra, Portugal. Degree: PhD in Cardiology, 2000. Coimbra University Hospital, Coimbra, Portugal (1985-1986). Coimbra University Hospital, Coimbra, Portugal (1987-1991). National Institutes of Health (Bethesda, USA) (1997-1998). Professional Qualifications: Cardiologist by the Portuguese Medical Association in 1992. Fellow of the European Society of Cardiology in 2001 European Cardiology Diploma in 2002 Chief of Clinic in 2009 Actual Position: Senior Invasive Cardiologist - Cardiology Department at the Coimbra University Hospital (since 1991) Head of the Cardiology Department at the Coimbra University Hospital Center-GH (since 2013) Medical School Position: Lecturer of Cardiology - University of Coimbra Medical School (1994-1999). Associated Professor - University of Coimbra Medical School (since 2012). Coordinator for the teaching of Cardiology at the University of Coimbra Medical School (since 2012).

Honorific titles: Gold medal from the Loulé Municipality (2001). Silver medal from the European Society of Cardiology (2010). Honorary Professor from the University of Moscow-Pirogov (2013). Honorary member of the Hungarian Society of Cardiology (2014). Scientific Awards: Luso-Fármaco and Portuguese Society of Cardiology Award on Ischemic Heart Disease (1990) Luso-Fármaco and Portuguese Society of Cardiology Award on Ischemic Heart Disease (1992) Pfizer Award from the Portuguese Medical Society (1995) Hoecht and Portuguese Society of Cardiology Award on Ischemic Heart Disease (1996) Luso-Fármaco and Portuguese Society of Cardiology Award on Ischemic Heart Disease (1996) Heart Disease (1996) Heart Disease (2000) Young Investigator Award Scientific Conference On Molecular, Integrative, And Clinical Approaches To Myocardial Ischemia of the American Heart Association Heart Disease (2001) Servier and Portuguese Society of Cardiology Award on Heart Failure (2001) Aventis and Portuguese Society of Cardiologfy Award (2002) Young Investigator Award on Basic Sciences of the Portuguese Society of Cardiology (2002) João Porto Award of the Portuguese Socitey of Cardiology (2002) Young Investigator Award on Basic Sciences of the Portuguese Society of Cardiology (2003) Honourable mention of the Bial Award (2004) Heart Disease (2006) João Porto Award of the Portuguese Society of Cardiology (2010). Co-author of the Young investigator award from the Portuguese Society of Cardiology (2010) Co-author of the Young investigator award from the Portuguese Society of Cardiology (2012) Co-author of the Basic Science award from the ESC Congress (2013) 1

Portuguese Society of Cardiology Officer: Assistant Secretary of the Portuguese Society of Cardiology (1995-1996) Vice-President of the Portuguese Society of Cardiology (2001-2003); (2003-2005); (2011-2013) Representative of the Portuguese Society of Cardiology in the UEMS - Cardiology Section (since 2001-2009) Board Member of the PCI Working Group of the Portuguese Society of Cardiology (2007-2010) President of the XXXIII Portuguese Congress of Cardiology (2012) Portuguese Medical Association - College of Cardiology: Board Member (2000-2003) Director of the National Center for the Collection of Data in Cardiology (2003-2006); (2011-1013) Co-Director of the Harvard Medical School Portugal CRST program (since 2012) Coimbra University Faculty of Medicine: Member of the Scientific Council Member (since 2012) Member of the Internal Scientific Committee (since 2012) Member of the PhD Program Committee (since 2012) Member of the Advanced Studies Program Committee (since 2012) Chairman of the Cardiovascular Strategic Area (since 2013) Cardiology Department Basic Research Unit Coordinator (since 1995) Portuguese National Ethics Committee for Clinical Research Board member (since 2011) UEMS European Union of the Medical Specialists (Cardiology Section): EBAC - European Board for Accreditation in Cardiology: Steering Committee Member (2001-2008) Representative of the UEMS-Cardiology Section at the Multidisciplinary Joint Committee of Intensive Care Medicine (2001-2003) Representative of the UEMS-Cardiology Section at the EBAC (2001-2008) Secretary of the UEMS-CS (2006-2008) Steering Committee Member (2002-2008) EBAC Chairman (2004-2008) 2

EAPCI- European Association of PCI Board Member and Chair of the Education Committee (2009-2016). ESC - European Society of Cardiology: Board member of the Cellular biology of the heart WG (2005-2010) Education Committee Board member (2006-2016) ESC Board member - Councillor (2008-2010) Editor-in-Chief of the Reports of the ESC Congress (2009-2013) Web Advisory Board Member of the ESC (2008-2013) Chair of the Tasf Force for the development of the ESC web s search engine (2008-2013) Chair of the Task Force for the development of the ESC Educational on-line Platform (2010-2014) ESC Spokesperson on CME/Accreditation/Certification Membership: Portuguese Society of Cardiology European Society of Cardiology Member of the Basic Science Council - American Heart Association Member of the Clinical Cardiology Council - American Heart Association Working Group Cellular Biology of the Heart - European Society of Cardiology Editorial Board: Bulletin of the Portuguese Society of Hemorrheology and Microcirculation (1995-1997) Cardiovascular Research (since 1999) European Heart Journal (2002-2005) Portuguese Risk Fators Journal (since 2008) European Heart Journal International Editorial Board (Since 2013) Editor of the Clinical Problem Solving Section for the European Heart Journal (Since 2013) Supplements Editor For the Portuguese Journal of Cardiology (1999-2001) Invited Editor: For the Supplement of the Portuguese Journal of Cardiology Molecular Biology in Cardiovascular Diseases (1998). For the Supplement of the Portuguese Journal of Cardiology The Commemoration of the 50th Anniversary of the Portuguese Society of Cardiology For a Spotlight Issue of Cardiovasvular Research dedicated to the topic: Angiogenesis (2001) For a Spotlight Issue of Cardiovascular & Hematological Disorders - Drug Targets dedicated to the topic: New challenges in stem cells treatment (2010). 3

Scientific Council For the Portuguese Journal of Cardiology (since 2000). Reviewer: Cardiovascular Research (regular and fast-track reviewer) European Heart Journal Eurointervention Pharmacol Res Molecular Medicine Archives of Biochemistry and Biophysics Nutrition Metabolism and Cardiovascular Diseases Life Sciences Proteomics Cytotherapy Portuguese Journal of Cardiology Acta Medica Portuguesa Portuguese Journal of general Practice Research and Publications: Three-hundred and twenty-one presentations at International Congresses and other Scientific Meetings. Sixty-one papers published in international journals. Three hundred and ninety-nine presentations at Portuguese Congresses and other Portuguese Scientific Meetings. Eighty-six papers published in Portuguese publications. Research interests in Cardiovascular Diseases: Clinical: Coronary Artery Disease; Interventional Cardiology Translational: Angiogenesis; Stem cells 4