Advances in Heart Disease Prevention and Rehabilitation. Saturday, March 9, Helping Patients Help Themselves. Saturday, March 9, 2019

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11th Annual Advances in Heart Disease Prevention and Rehabilitation Helping Patients Help Themselves Saturday, March 9, 2019 Saturday, March 9, 2019 Detroit Marriott Troy Troy, Michigan Detroit Marriott Troy Troy, Michigan Supported by The Lois Walts Farrell Education and Training Fund

Introduction Recent studies have shown that arterial inflammation plays a key role in the development and progression of atherosclerosis, that acute myocardial infarctions often evolve from mild-to-moderate coronary artery stenoses, that patients who experience a fatal coronary event invariably had antecedent exposure to one or more major coronary risk factors (i.e., hypercholesterolemia, hypertension, cigarette smoking, diabetes, obesity), that angiographic findings may vastly underestimate underlying atherosclerotic coronary artery disease, and that aggressive medical management may represent a safe and effective alternative to many elective coronary revascularization procedures. Moreover, cardiorespiratory fitness appears to be one of the strongest prognostic markers in persons with and without heart disease. Collectively, these data highlight the value of lifestyle modification and contemporary pharmacotherapies in the prevention of initial and recurrent cardiovascular events. Several mechanisms may contribute to improved clinical outcomes, including partial (albeit small) anatomic regression of coronary artery stenoses, a reduced incidence of coronary inflammation, platelet aggregation, and plaque rupture, and enhanced coronary artery vasomotor function. Conference registrants will be provided the latest information on heart disease prevention and rehabilitation by a nationally distinguished faculty to help patients help themselves. Target audience This one-day conference will provide cardiologists, internists, physician assistants, cardiac nursing personnel, and associated allied health professionals (e.g., physiologists, physical and occupational therapists, cardiac rehabilitation personnel, dietitians, recreational directors, public health professionals, health care administrators) with an overview of recent advances in the primary and secondary prevention of cardiovascular disease. CME accreditation and credit designation Beaumont Health is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Beaumont Health designates this live activity for a maximum of 5.75 AMA PRA Category 1 Credit(s). Physicians should claim only the credit commensurate with the extent of their participation in the activity. Disclosure All planning committee members and speakers have been asked to disclose any significant relationships they may have with commercial companies within the past 12 months that are relevant to their presentation. The presence or absence of relationships as well as off-label discussion of products will be disclosed at the time of the conference. Acknowledgement This conference will be partially supported by educational grants and display fees from commercial supporters.

OBJECTIVES By attending this conference, attendees should improve their ability to: Describe the healthcare needs of an aging population, the importance of rebranding traditional cardiac rehabilitation programs, and the value in reaching out to families to facilitate these objectives Summarize the rationale for the changes made in the most recent American College of Cardiology/ American Heart Association guidelines on the management of hypertension Assess the strengths and limitations of traditional atherosclerotic cardiovascular disease risk assessment and examine their impact on blood pressure management Describe the changes in creatine kinase and cardiac troponin that occur with vigorous exercise and their clinical significance Identify potential mechanisms by which high volume, high-intensity exercise training may increase the risk of atrial fibrillation Review the inherited cardiac condition where habitual vigorous exercise appears to worsen prognosis Clarify the pathophysiology of lipoprotein (a), an emerging novel target for therapy, and review current and future approaches to treatment Review the individual and collective impact of increased physical activity, proper nutrition, weight management and avoidance of tobacco products, on lowering the risk of heart disease, diabetes and other chronic metabolic conditions, and the emerging field of Lifestyle Medicine Review an interesting case study pertaining to a patient with cardiovascular disease (e.g., atherosclerotic coronary artery disease and/ or structural abnormalities), including the diagnostic evaluations employed, the treatment approach used, and related cardiovascular outcomes Discuss the cardiac and non-cardiac benefits of daily aspirin and the management of patients on varied anticoagulation therapies Understand the proximate cause of acute myocardial infarction, as well as the morphology, detection, and potential management of vulnerable coronary plaque Review the role of vitamin and mineral supplements for the primary and secondary prevention of cardiovascular disease, with specific reference to potential mechanisms of benefit and which supplements may be harmful Identify the role of evidence-based integrative medicine approaches in the prevention of chronic disease, and the fundamentals in guiding patients toward complementary mind/body techniques Understand the causes of sudden death in young athletes and the relative roles and efficacy of different screening strategies Identify the barriers and facilitators to adoption of healthy lifestyle behaviors in medically-supervised, home-based and worksite settings Summarize the evidence supporting the role of selected physical, chemical, and psychological stressors in the triggering of acute cardiovascular events, as well as the potential role of various preventive interventions, including cardioprotective medications and regular moderate-to-vigorous intensity exercise training

FACULTY Director Barry A. Franklin, Ph.D. Director, Preventive Cardiology and Rehabilitation Beaumont Health, Royal Oak Professor, Department of Internal Medicine Oakland University William Beaumont (OUWB) School of Medicine Guest Faculty Kathy Berra, MSN, NP Nurse Practitioner, Cardiovascular Medicine and Coronary Interventions Redwood City, CA Stanford Prevention Research Center (Retired) Roger S. Blumenthal, M.D. The Kenneth Jay Pollin Professor of Cardiology Director, The Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease Baltimore, MD Steven N. Nissen, M.D. Chairman, Department of Cardiovascular Medicine Cleveland Clinic Foundation Cleveland, OH James M. Rippe, M.D. Cardiologist, Founder/Director Rippe Lifestyle Institute Shrewsbury, MA Beaumont Faculty Aaron D. Berman, M.D. Clinical Chief, Cardiovascular Medicine Associate Professor, Department of Internal Medicine Abhay Neil Bilolikar, M.D. Director, Echocardiography Lab Assistant Professor of Medicine Allan W. Chernick, M.D. Staff Cardiologist Harold Z. Friedman, M.D. Medical Director, Preventive Cardiology and Cardiac Rehabilitation Associate Professor, Department of Internal Medicine Abdul R. Halabi, M.D. Interventional Cardiologist Assistant Professor, Department of Internal Medicine Ivan D. Hanson, M.D. Interventional Cardiologist Assistant Professor of Medicine Andrew M. Hauser, M.D. Staff Cardiologist Paul D. Thompson, M.D. Chief of Cardiology Hartford Hospital Hartford, CT Gail Elliott Patricolo, B.A. (Hons), Grad CertCAM Director, Integrative Medicine Steven B.H. Timmis, M.D. Director, Coronary Care Unit Assistant Professor, Department of Internal Medicine Justin E. Trivax, M.D. Interventional Cardiologist Assistant Professor of Medicine

SCHEDULE OF EVENTS 7:15 7:50 a.m. Registration and Continental Breakfast 7:50 8:00 a.m. Welcome and Opening Remarks Barry A. Franklin, Ph.D. 8:00 8:35 a.m. Should Everyone Take an Aspirin Every Day? Justin E. Trivax, M.D. 8:35 9:10 a.m. Lipoprotein(a): An Emerging Novel Target for Therapy Steven E. Nissen, M.D. 9:10 9:45 a.m. Blood Pressure How Low to Go and How to Do it Safely Roger S. Blumenthal, M.D. 9:45 10:20 a.m. Can Too Much Exercise Hurt the Heart? Paul D. Thompson, M.D. 10:20 10:50 a.m. Case Presentation Neil Bilolikar, M.D. (Discussants: Allan W. Chernick, M.D.; Abdul R. Halabi, M.D.; Andrew M. Hauser, M.D.; Steven B.H. Timmis, M.D.; Justin E. Trivax, M.D.) 10:50 11:10 a.m. BREAK 11:10 11:45 a.m. Expanding Your Reach, Increasing Access to Cardiopulmonary Services and Empowering Life Long Wellness Kathy Berra, MSN, NP 11:45 12:20 p.m. Are We Ready to Practice Lifestyle Medicine? James M. Rippe, M.D. 12:20 12:35 p.m. Panel Discussion/Questions and Answers 12:35 1:30 p.m. LUNCH HOT TOPICS BRIEF UPDATES 1:30 1:50 p.m. Triggers of Acute Cardiovascular Events and Potential Preventive Strategies Barry A. Franklin, Ph.D. 1:50 2:10 p.m. Influenza and Cardiovascular Disease Ivan D. Hanson, M.D. 2:10 2:30 p.m. Vitamins and Mineral Supplements for Primary and Secondary Prevention of Cardiovascular Disease Aaron D. Berman, M.D. 2:30 2:45 p.m. BREAK 2:45 3:05 p.m. An Integrative Medicine/Mind Body Approach to Prevention Gail Elliott Patricolo, B.A. (Hons), Grad CertCAM 3:05 3:15 p.m. Q&A 3:15 p.m. Adjournment

REGISTRATION Register on or before Feb. 28, 2019 to take advantage of reduced registration rates. Register online at: https://beaumont.cloud-cme.com/prevention2019 Early bird registration rates are available until 2/28/19. Online registration will close on 3/8/19. After 3/8/19, you may register onsite at the registration desk. Registration Fees Conference registration fees include CME credit, access to online presentations, continental breakfast, lunch and breaks. Location Detroit Marriott Troy 200 West Big Beaver Road Troy, MI 48084 Phone: 248-680-9797 Early Bird On or before After 2/28/19 2/28/19 Attending Physician $149 $199 Physicians-in-training, $75 $99 NP, RN, PA-C other cardiac care providers Students $30 $40 (must show College ID at Registration) Accommodations Rooms are available at the Detroit Marriott Troy at a rate of $107/night double/king. To book a room at the discounted rate, call 877-757-7131 or 248-680-9797 and ask for the Beaumont PREVENTION group rate. Cancellation Policy Cancellation requests received on or before Feb. 28, 2019 are fully refundable. Cancellations or refunds after this date will not be honored. Substitutions are permitted. To cancel a registration, send an email to heartandvascularconferences@beaumont.edu or fax 248-898-9075. Any questions Call 800-732-6368 or email: heartandvascularconferences@beaumont.edu

REGISTRATION FORM 11th Annual Advances in Heart Disease Prevention and Rehabilitation Saturday, March 9, 2019 Early bird registration fees are available until Feb. 28, 2019. Online registration closes on March 8, 2019. After March 8, 2019, you may register onsite at the registration desk. Questions? Call 800-732-6368 or email: heartandvascularconferences@beaumont.edu To register Online https://beaumont.cloud-cme.com/prevention2019 Fax 248-898-9075 Mail Completed registration form and payment: Kathryn Tewilliager Department of Cardiovascular Medicine Beaumont Hospital 3601 West 13 Mile Road Royal Oak, MI 48073-6769 NAME MD DO PAC NP RN OTHER ADDRESS CITY, STATE ZIP INSTITUTION CITY, STATE (FOR NAME BADGE) TELEPHONE FAX EMAIL ADDRESS Specialty Clinical cardiology Interventional cardiology Internal medicine Family practice Other Registration Fees On or before 2/28/19 After 2/28/19 Attending physician $149 $199 Physicians-in-training, NP, RN, PA-C, $75 $99 other cardiac care providers Students (must show College ID at registration) $30 $40 Method of Payment Make checks payable to: Beaumont Health Credit card: Visa Mastercard Discover American Express CREDIT CARD NO. EXPIRATION DATE SECURITY CODE NAME ON CREDIT CARD (PRINT) SIGNATURE

Department of Cardiovascular Medicine 3601 West 13 Mile Road Royal Oak, MI 48073-6769 11th Annual Advances in Heart Disease Prevention and Rehabilitation Helping Patients Help Themselves Saturday, March 9, 2019 Detroit Marriott Troy Troy, Michigan Supported by The Lois Walts Farrell Education and Training Fund