The diagram shows four ways in which molecules may move into and out of a cell. The dots show the concentration of molecules.

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The diagram shows four ways in which molecules may move into and out of a cell. The dots show the concentration of molecules. The cell is respiring aerobically. Which arrow, A, B, C or D, represents: (i) movement of oxygen molecules; movement of carbon dioxide molecules? Name the process by which these gases move into and out of the cell. () (c) Which arrow, A, B, C or D, represents the active uptake of sugar molecules by the cell? Explain the reason for your answer. (Total 5 marks) Page of

The diagram shows a human sperm. Inside the tail of the sperm is a filament mechanism that causes the side to side movement of the tail, which moves the sperm. Describe the function of the mitochondria and suggest a reason why they are arranged around the filament near the tail of the sperm. () Explain the significance of the nucleus in determining the characteristics of the offspring. (Total 5 marks) Page of

Some students set up this experiment to investigate osmosis. They filled two pieces of dialysis [visking] tubing with different liquids and left them both in a beaker of 5% sucrose solution for an hour. Describe and explain the likely results after one hour. (6) Describe two examples where osmosis is used in living things. (Total 8 marks) Page of

4 The diagrams show a cheek cell from a human and a leaf cell from a plant. The two cells have a number of parts in common. (i) On the cheek cell, label three of these parts which both cells have. In the table, write the names of the three parts you have labelled above and describe the main function of each part. () Part Function () Blood contains white cells and red cells. State the function of each type of cell in the blood. White cells Red cells (Total 8 marks) Page 4 of

5 The drawing shows an animal cell, seen at a very high magnification using an electron microscope. (i) Label a mitochondrion [plural = mitochondria]. () What happens in the mitochondria? (i) Name and label the structure where you would find chromosomes. () () What are chromosomes made of? () (c) What controls the rate of chemical reactions in the cytoplasm? () (Total 5 marks) Page 5 of

6 The drawing shows a white blood cell ingesting a bacterium. Label the parts of the white blood cell. (Total marks) 7 The drawing shows part of a root hair cell. Use words from the list to label the parts of the root hair cell. cell membrane cell wall cytoplasm nucleus vacuole (4) The diagram shows four ways in which molecules may move into and out of a cell. The dots show the concentration of molecules. Page 6 of

The cell is respiring aerobically. Which arrow, A, B, C or D represents: (i) movement of oxygen molecules; movement of carbon dioxide molecules? (c) Name the process by which these gases move into and out of the cell. () (Total 7 marks) 8 Capillaries are blood vessels in the body which join the arteries to the veins. They have walls which are one cell thick and so are able to exchange substances with the body cells. (i) Name two substances that travel from the muscle cells to the blood in the capillaries... Glucose is one substance that travels from the blood in the capillaries to the body cells. Explain how this happens. (Total 4 marks) Page 7 of

Mark schemes (i) A B for mark each diffusion (reject osmosis) for one mark (c) C because uptake against a concentration / diffusion gradient (reject osmosis) (if C not given, then idea of movement essential) for mark each [5] award one mark for each key idea energy released or energy transferred or respiration allow provides or gives do not allow produces or makes near to the site of movement or energy available quickly or more energy accept allows more mitochondria to fit in (mitochondria) packed (around filament) or efficient arrangement or spiral arrangement contains chromosomes or genes or DNA not genetic material (which) contribute half (the genes) to the fetus or offspring chromosomes or half the genes or reference to X,Y chromosome determining sex (if the notion of halfness is there) nucleus contains half genes for the offspring = marks [5] Page 8 of

award marks per tube for each key idea for tube : expands or gets firmer or bigger or inflates it gains water because the concentration of water is less than its surroundings make sure answer is about water movement and not sucrose solution for tube gets floppy or flaccid or contracts it loses water because the concentration of water is greater than its surroundings any from: uptake of water by root (hair) or movement from cell to cell within plant guard cell function maintain turgor do not credit references to diffusion unless it is clear that the candidate is referring to the diffusion of water water absorption in the large intestine reabsorption of water from the nephron or collecting duct or in kidney or osmoregulation in kidney allow osmosis in other animals if some use is shown [8] Page 9 of

4 (i) the three features correctly labelled on cheek cell (which are referred to in part label lines should touch or end very close to part no marks if leaf cell labelled nucleus cytoplasm cell membrane mitochondrion accept mitochondria or one of these could be labelled vacuole any three from feature function nucleus cytoplasm occurs membrane chemicals controls cell accept contains genetic material or genes or chromosomes or stores information do not credit the brain of the cell where respiration accept contains food or mitochondria or reactions occurs less water or accept surrounds the cell or lets some things in but not others do not credit keeps things out or protection in and or out mitochondria where energy released ecf from leaf cell labelling accept chloroplasts make sugar or glucose accept vacuole contains sap accept if cell wall mis labelled on cheek cell, support or hold together Page 0 of

fight or ingest or kill bacteria or germs or viruses or microbes accept produce antitoxins or antibodies fight disease (organisms) do not credit fungus (transport) oxygen or carry haemoglobin accept transport carbon dioxide or helps form scabs [8] 5 (i) award mark for any of the mitochondria correctly labelled if a number are labelled and one is incorrect award 0 marks respiration or the release or transfer of energy or it contains the enzymes for respiration do not accept energy produced Page of

(i) nucleus (named and correctly labelled) arrow or line must touch or go inside the nuclear membrane DNA or genes or nucleic acids accept protein or histones or nucleotides or ATGC (c) enzymes or nucleus do not accept factors that affect the rate rather than control it eg ph or temperature [5] 6 cytoplasm reject protoplasm (cell) membrane nucleus all correctly labelled each for mark [] 7 (cell) wall (cell) membrane cytoplasm vacuole for mark each 4 (i) A B for mark each (c) diffusion (reject osmosis) for mark [7] Page of

8 (i) any two from: urea carbon dioxide water lactic acid higher concentration of glucose or more glucose in blood than cells diffuses across [4] Page of