Palliative Care Emergencies. Additional module if needed

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Palliative Care Emergencies Additional module if needed

Learning objectives Understand emergency /urgent / important Describe common emergencies in PC Explore principles of essential management Outline management for specific common emergencies in PC

Questions In any given situation we must use knowledge know what we could do skill know what we should do attitude know how we should do diplomacy know what the patient wants us to do / not do judgement make an active/ negotiated decision

Emergencies severe pain confusion spinal cord compression fractures metabolic - hypercalcaemia seizures haemorrhage superior vena cava obstruction respiratory obstruction

Total Pain PHYSICAL EMOTIONAL SOCIAL SPIRITUAL

Confusion confusion up to 75% patients advanced illness often fluctuates terminal restlessness (mild) terminal delerium (severe)

Confusion Causes biochemical / drugs pain cerebral irritation infection constipation / retention hypoxia / respiratory distress anxiety / spiritual distress

Confusion Management treat reversible causes stop medications / insert catheter / start antibiotics / treat constipation adjust environment familiar voices, music, soft lighting, avoid loud noise / don t use restraints explain / support family needs pharmacological intervention

Confusion Management use sedatives symptom relief neuroleptics - anxiolyic /antipsychotic haloperidol / olanzepine / chlorpromazine haloperidol 5mg po/sc as required and repeat benzodiazepines - anxiolytic / sedative midazolam / lorazepam / diazepam midazolam 2.5mg sc / diazepam 5mg od

Spinal Cord Compression Incidence 3% patients advanced cancer > one level 20% common breast bronchus prostate

Spinal Cord Compression Mechanism metastatic spread to bone 85% direct tumour extension 10% intramedullary primary 4% haematogenous spread to epidural space 1%

Spinal Cord Compression Presentation pain >90% weakness >75% sensory level >50% sphincter dysfunction >40% nb. pain usually predates other symptoms

Spinal Cord Compression Diagnosis history and clinical findings plain x-ray?bone scan?mri?ct / myelogram

Spinal Cord Compression Management corticosteroids dexamethasone 16-32mg radiotherapy as soon as possible surgery

Spinal Cord Compression Outcome poor prognosis loss of sphincter control rapid onset complete paraplegia better prognosis early detection and treatment cauda equina lesion incompete paraplegia

Fracture common with metastatic bone disease may be terminal event management anticipate radiotherapy surgery neuraxial therapies

Hypercalcaemia commonest metabolic complication rate of rise determines emergency common up to 50% breast and myeloma lung / renal / cervix / head and neck diagnosis thirst / polyuria / confusion / pain / nausea and vomiing / constipation / dehydration / coma

Hypercalcaemia investigation serum calcium / albumin / renal function management rehydrate bisphosphonates pamidronate 60mg treat underlying disease

Seizures Causes cerebral metastases cerebral infection / oedema cerebral haemorrhage biochemical derangement premorbid epilepsy

Seizures Treatment emergency maintain airway pharmacology diazepam 10mg pr midazolam 5-10mg sc/iv phenobarbitol 100mg sc or in 100mls saline over 30mins consider steroids

Haemorrhage fear often worse than reality more common GI / lung / pelvic / head and neck management radiotherapy surgery

Haemorrhage Management topical mild oozing topical sucralfate moderate oozing dilute hemloc (adrenaline 1:1000 soaked swab)

Haemorrhage Management oral ethamsylate 500mg QID (tranexamic acid) sucralfate 1g bd-qds 1% alum bladder irrigation

Massive Haemorrhage Management anticipate prevent (if possible) keep calm skilled person (if available) sedation (if possible) benzodiazepine / morphine vaginal pack / local measures / surgery

SVCO Superior venal cava obstruction 75% SVCO is in lung carcinoma extrinsic compression / mediastinum symptoms/signs depend on extent and speed of development symptoms worse on lying flat facial +/- arm swelling engorged neck and chest wall veins

SVCO Management stat iv dexamethasone 8-16mg then po?urgent referral for radiotherapy stent?chemotherapy

Respiratory Obstruction acute reversible or irreversible? relieve symptoms regardless of cause Pharmacological parenteral morphine s/l lorazepam 0.5-2.0 mg PRN / parenteral midazolam?steroids - dexamethasone Non-pharmacological fan, presence

Stridor acute stridor is very rare iv dexamethasone stat iv midazolam, if severe agitation? referral for stent /DXT

Conclusions can be physical, social, spiritual, psychological can cause team tension challenge opportunity bridges specialties teamwork

These resources are developed as part of the THET multi-country project whose goal is to strengthen and integrate palliative care into national health systems through a public health primary care approach Acknowledgement given to Cairdeas International Palliative Care Trust and MPCU for their preparation and adaptation part of the teaching materials for the Palliative Care Toolkit training with modules as per the Training Manual can be used as basic PC presentations when facilitators are encouraged to adapt and make contextual