360º MIND ENDOSCOPIC ENDONASAL & KEYHOLE SURGERY OF THE SKULL

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360º MIND ENDOSCOPIC ENDONASAL & KEYHOLE SURGERY OF THE SKULL BASE, PITUITARY FOSSA, ORBIT AND CRANIO-CERVICAL JUNCTION: A COMPREHENSIVE HANDS-ON COURSE November 12-15, 2010 360º Mind Faculty Ricardo L. Carrau, MD Amin B. Kassam, MD Daniel F. Kelly, MD Guest Faculty Juan Fernandez-Miranda, MD Chester F. Griffiths, MD, FACS Howard Krauss, MD Dennis Malkasian, MD, PhD Daniel M. Prevedello, MD Fairmont Miramar Hotel & Bungalows 101 Wilshire Boulevard SPONSORED BY

360º MIND ENDOSCOPIC ENDONASAL & KEYHOLE SURGERY OF THE SKULL BASE, PITUITARY FOSSA, ORBIT AND CRANIO-CERVICAL JUNCTION: A COMPREHENSIVE HANDS-ON COURSE COURSE DESCRIPTION This is a comprehensive course that will thoroughly cover current indications, limitations and surgical techniques for endoscopic endonasal surgery of the skull base, pituitary fossa, orbit and craniocervical junction. The course will also cover the indications, limitations and surgical techniques for the supraorbital keyhole craniotomy approach. Our faculty will present the technical nuances and technological requirements of these surgeries, using a modular anatomical system that can be translated to the dissection laboratory. Current indications, advantages, limitations and outcomes will be discussed. The course comprises a sequence of complementary didactic lectures, prosections, 3-D anatomical reviews and hands-on cadaver dissection. A live surgical demonstration will be transmitted directly to the auditorium where the participants may interact with the surgeons and other members of the faculty. COURSE OBJECTIVES At the conclusion of this activity, participants should be able to: 1. Understand the anatomic relationships of the sinonasal tract, orbit and ventral skull base from the endoscopic perspective 2. Understand the indications and limitations of endoscopic endonasal surgery of the skull base, pituitary fossa, orbit and craniocervical junction 3. Understand how to avoid and treat complications of endoscopic endonasal surgery of the skull base, pituitary fossa, orbit and craniocervical junction 4. Understand the anatomic relationships and surgical exposure afforded by the supraorbital keyhole surgical approach 5. Understand the relative anatomical exposures of the endonasal versus the supraorbital approaches for parasellar and paraclival lesions 6. Understand how to avoid and treat complications of keyhole skull base surgery TARGET AUDIENCE: Neurosurgeons, otolaryngologists-head and neck surgeons and other skull base surgeons who are interested in learning endoscopic endonasal surgery of the skull base, pituitary fossa, orbit and craniocervical junction. www.endokeyhole.org www.brain-tumor.org

360º MIND Faculty Ricardo L. Carrau, MD, FACS Amin B. Kassam, MD Director, Neuroscience Institute FACULTY Daniel F. Kelly, MD Director, Brain Tumor Center Fellows Nancy McLaughlin, MD Leo Ditzel Filho, MD Guest Faculty Juan C. Fernandez-Miranda, MD Assistant Professor of Neurological Surgery Director, Surgical Neuroanatomy Lab Department of Neurological Surgery University of Pittsburgh - UPMC Pittsburgh, Pennsylvania Chester F. Griffiths, MD, FACS Assistant Clinical Professor, Department of Surgery, Division of Head and Neck Surgery & Department of Family Practice Chief of Otolaryngology Head and Neck Surgery Santa Monica-UCLA Orthopaedic Hospital Medical Director, West Wilshire Medical Surgical Center Howard R. Krauss, MD Clinical Professor of Ophthalmology and Neurosurgery Dennis Malkasian, MD, PhD Associate Clinical Professor of Neurosurgery Daniel M. Prevedello, MD Assistant Professor Department of Neurological Surgery Ohio State University Columbus, Ohio ACCREDITATION (SJHC) is accredited by the Institute for Medical Quality/California Medical Association to provide continuing medical education for physicians. SJHC takes responsibility for the content, quality and scientific integrity of this CME activity. SJHC designates this educational activity for a maximum of 39.25 AMA PRA Category 1 Credits. Physicians should only claim credit commensurate with the extent of their participation in the activity. This credit may also be applied to the CMA Certification in Continuing Medical Education. ACKNOWLEDGEMENT This course is supported in part by educational grants from the following companies at press time: Stryker, Karl Storz Endoscopy, Anspach Companies, Medtronic, Leica Microsystems, KLS Martin, Biomet Microfixation, NICO Corporation. DISCLOSURE STATEMENT The FDA has issued a concept paper which classifies commercial support of scientific and educational programs as promotional unless it can be affirmed that the program is truly independent and free of commercial influence. In addition to independence, the FDA requires that non-promotional, commercially supported education be objective, balanced, and scientifically rigorous. The policy further states that all potential conflicts of interest of the CME staff and faculty be fully disclosed to the program s participants. In addition, Accreditation Council for Continuing Medical Education policy now mandates that the sponsor adequately manages all identified potential conflicts of interest prior to the program. We, at, fully endorse the letter and spirit of these concepts.

AGENDA FRIDAY, NOVEMBER 12, 2010 DAY 1 7:00 am Registration & Continental Breakfast 7:45 Welcome and Course Overview 8:00 Level I and II Approaches: How to Talk and Walk Like an ENT Surgeon Ricardo L. Carrau 8:45 Principles of Endoscopic Endonasal Extended Approaches Amin B. Kassam 9:30 Graded CSF Leak Repair Technique in Endonasal Surgery Daniel F. Kelly 10:00 Break 10:15 Reconstruction: The Hadad-Bassagasteguy Flap and Other Phat Vascularized Flaps Ricardo L. Carrau 11:00 Approaches to the Sella and Parasellar Regions: The Beginning of EndoSBS Ricardo L. Carrau & Amin B. Kassam 11:30 Lunch Lecture: Sagittal Plane Modules I: Pituitary, Transplanum, and Transcribriform Daniel M. Prevedello 12:00 pm Lunch Lecture: Maximizing Pituitary Gland Function in Pituitary & Parasellar Surgery Daniel F. Kelly 1:00 Craniofacial Resection of Sinonasal Malignancy: Myths, Principles and Outcomes Ricardo L. Carrau 1:30 Lab 1 Anatomical Prosection: The Sagittal Plane: Trans-sellar Ricardo L. Carrau & Juan Fernandez-Miranda 2:45 Anatomical Dissection 5:30 End of Day 1 7:00-9:30 Course Dinner SATURDAY, NOVEMBER 13, 2010 DAY 2 7:00 am Continental Breakfast 8:00 Sagittal Plane Modules II: Transclival, Transodontoid Amin B. Kassam 9:00 3-D Endoscopic Skull Base Anatomy: The Sagittal Plane Juan Fernandez-Miranda 10:00 Break 10:30 Lab 2 Anatomical Prosection: Sagittal Plane II Trans-planum, Trans-cribiform Ricardo L. Carrau & Daniel M. Prevedello 11:30 Lunch 12:30 pm Anatomical Dissection 4:00 Anatomical Basis for the Transpterygoid Approaches Ricardo L. Carrau 5:00 Coronal Plane Modules Amin B. Kassam 6:00 End of Day 2 SUNDAY, NOVEMBER 14, 2010 DAY 3 7:30 am Continental Breakfast 8:00 3-D Endoscopic Skull Base Anatomy: Coronal Plane Juan Fernandez-Miranda 9:00 Lab 3 Anatomical Prosection: Transclival, Trans-nasal odontoidectomy Ricardo L. Carrau & Daniel M. Prevedello 10:00 Special Prosection: Orbital Approaches Chester F. Griffiths & Howard R. Krauss 11:00 Anatomical Prosection: Transpetrous Approaches 12:00 pm Lunch Lecture: Prevention and Management of Neurosurgical Complications Amin B. Kassam 1:30 Anatomical Dissection 4:00 Lab 4 Prosection: Infratemporal Fossa Ricardo L. Carrau & Daniel M. Prevedello 5:00 Anatomical Dissection 6:30 End of Day 3 and Labs 1-4 MONDAY, NOVEMBER 15, 2010 DAY 4 7:30 am Continental Breakfast 8:00 360-Degree Minimally Invasive Brain Surgery A Concept & Practical Approach Daniel M. Prevedello 8:30 Parasellar Surgical Anatomy Dennis Malkasian 9:00 3-D Surgical Anatomy of Parasellar Space, Frontal Fossa & Proximal Sylvian Fissure Juan Fernandez-Miranda 9:30 Supraorbital Eyebrow Craniotomy for Suprasellar and Planum Pathology: Operative Technique and Eyebrow vs Endonasal Decision Making Daniel F. Kelly 10:00 Lab 5 Prosection: Supraorbital Eyebrow Craniotomy Daniel F. Kelly 10:45 Break 11:00 Hands-on Dissection: Supra-Orbital Eyebrow Craniotomy 1:30 pm Adjourn

COURSE LOCATION AND HOTEL ACCOMMODATIONS FAIRMONT MIRAMAR HOTEL & BUNGALOWS 101 Wilshire Boulevard 90401 Telephone: (310) 576-7777 www.fairmont.com TRAVEL (Airfare) Cooks Travel Cindy Miller cindy@trtravel.net 800.628.2665, extension 106 Closest airport is Los Angeles International Airport (LAX) The following shuttle companies operate shuttles from LAX to the Fairmont Miramar Hotel & Bungalows: SuperShuttle www.supershuttle.com/htm/cities/lax.htm Rate: USD $15.00 person Tel: +1(800) 258-3826 (US and Canada) REGISTRATION TUITION: November 12-15, 2010 Lectures and Lab 1-4 $3,000 Lectures and Lab 1-5 $3,500 Space is limited! Please print clearly. For hotel accommodations, call (310) 576-7777 or (800) 441-1414. Mention 360 MIND Course to get a special rate of $229 plus taxes. Parking rate at the hotel is $33 overnight, $15.40 day. Prices quoted are subject to change Prime Time Shuttle www.primetimeshuttle.com Rate: USD 15.00 per person, Tel:+1(800) 733-8267 (US and Canada) Space is Limited! Dietary Restrictions: SPECIALTY DEGREE NAME (FIRST, MIDDLE, LAST) ADDRESS CITY STATE ZIP (AREA CODE) BUSINESS PHONE (AREA CODE) BUSINESS FAX EMAIL Cancellations must be received in writing by October 1, 2010 and will be subject to a $200 processing fee. No refunds will be given after that date. If for any reason the course must be canceled, discontinued, or rescheduled by Academic Event Management, a full refund will be provided. PAYMENT Check enclosed payable to: Academic Event Management Visa MasterCard Discover American Express CARD NUMBER EXPIRATION SIGNATURE Send completed enrollment form to: Academic Event Management ONLINE PHONE 805.300.9154 www.academiceventmanagement.com FAX 805.494.1103 MAIL 1396 Rancho Lane Thousand Oaks, CA 91362