Epidemiology. Meniscal Injury & Repair. Meniscus Anatomy. Meniscus Anatomy

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Epidemiology 60-70/100,000 per year Meniscal Injury & Repair Arthroscopic Mensiscectomy One of the most common orthopaedic procedures 20% of all surgeries at some centers Male:Female ratio - 2-4:1 Younger patients acute traumatic incident Older patients degenerative tears Matthew Murray, MD Orthopaedic Sports Medicine Arthroscopic Surgery Ortho San Antonio 1/3 of all tears associated with ACL injury ACL Injury lateral meniscus tears more frequent Chronic ACL deficiency medial meniscus injury more prevalent Tibial Plateau Fractures Nearly 50% associated meniscal tears Meniscus Anatomy Medial Meniscus C-shaped Posterior horn larger than anterior horn Anchored to anterior and posterior bony attachments Coronary Ligament Remainder firmly attached to joint capsule Deep MCL Thickening of mid-portion of capsular attachment Meniscus Anatomy Lateral Meniscus Semi-Circular configuration Anchored to anterior and posterior bony attachments Much closer than Med Meniscus Anterior horn inserts adjacent to ACL Meniscofemoral Ligaments Humphrey anterior Posterior horn to femur Wrisberg posterior Can be only posterior attachment in Wrisberg Variant discoid meniscus Covers more tibial articular surface Capuslar attachments much less developed Allows increased translation of lateral meniscus with ROM

Arthroscopic Anatomy Microstructure Type I collagen (90%) Orientation mainly circumferential Allows dispersion of compressive loads Some radial fibers at surface and within mid-substance Resist longitudinal tearing Mesh orientation at surface Distribution of shear stresses Lateral Medial Blood Supply Birth entire meniscus is vascular 9 months inner 1/3 is avascular Decreased vascularity until 10yo Adult Meniscus vascularity PeriMeniscal Capillary Plexus Superior and Inferior branches of Medial and Lateral Genicular Arteries Lateral outer 10-25% Mostly avascular at Popliteal Hiatus Medial outer 10-30% Nerve Fibers Concentrated in outer portion of meniscus Dye et al. conscious neurosensory mapping Peripheral tissue mild to moderate discomfort Central tissue little or no pain awareness Mechanoreceptors in anterior and posterior horns Proprioceptive feedback

Meniscus Function 1897 Bland-Sutton the functionless remnants of the intra-articular leg muscles 1. Load Sharing 2. Reducing Joint Contract Stresses 3. Passive Stabilization 4. Increasing Congruity/Contact Surface Area 5. Limiting Flexion/Extension Extremes 6. Proprioception Meniscus Function Knee Extension 50-70% of load transmitted through menisci Knee Flexion 85% of load transmitted through menisci Total Medial Meniscectomy 100% increase in contact stress 50-70% reduction in femoral condyle contact area Total Lateral Meniscectomy 200-300% increase in contact stress 40-50% decrease in femoral condyle contact area ACL deficient Knee Medial Meniscus is most important resistance to anterior tibial force 50% increased load at full extension 200% increase load at 60deg flexion History Twisting or Hyperflexion Injury Pain, swelling Locking, catching Loss of motion, extension block Degenerative Tears Older patients Chronic history of mild swelling and pain Degenerative changes on Xrays Physical Exam Inspection Joint Effusion Quadriceps Atrophy Joint Line Swelling parameniscal cyst Range of Motion Mechanical block in extension Loss of flexion Palpation Medial and Lateral joint lines, patellofemoral joint Ligament Stability Testing Specialized Testing McMurry s Test Apley Grind Test

Diagnostic Studies Xrays IMPORTANT! Helpful for bony pathology and assessing degenerative changes Series PA 45deg flexion weight bearing view of both knees Lateral view Merchant Diagnostic Studies MRI 95% accuracy of detecting tears BUT must correlate clinically LaPrade 5.6% tears in asymptomatic 18-39 year olds with normal physical exam Boden MRI on asymptomatic patients < 45yo 13% positive for meniscal tear > 45yo 36% positive for meniscal tear Muellner equal effectiveness of clinical evaluation compared with MRI Classification of Meniscal Tears Vertical Longitudinal Tear

Bucket Handle Tear Oblique Parrot Beak Tear Horizontal Cleavage Tear Radial Tear

Complex Degenerative Tear Surgical Indications 1. Symptoms affect Activities of daily living Work Sports 2. Positive physical findings: Joint line tenderness Joint effusion Limited Range of Motion Provocative signs: Pain with Squatting Positive McMurry s or Apley s 3. Failure to respond to non-surgical management 4. Absence of other causes of knee pain identified on Xray or MRI Total Meniscectomy Previously a commonly performed procedure Considered benign 1948 Fairbank Joint space narrowing Osteophyte formation Squarring of femoral condyles 1987 Jorgensen 147 athletes, followed at 4.5 and 14.5 years Knee complaints 53%, 67% Knee Instability 10%, 36% Radiographic degenerative changes 40%, 89% 46% gave up or reduced sporting activity Arthroscopic Partial Meniscectomy 80-90% satisfactory results compared with open total meniscectomy Less invasive Decreased hospitalization Shorter recovery time 1992 Wroble 39 adolescents, 21 year follow up Pain 71% Stiffness 68% Swelling 54% Instability 41% 90% with abnormal x-rays in affected compartment Overall 63% unsatisfactory results

Arthroscopic Partial Meniscectomy BUT not a completely benign procedure Still a progression of degenerative changes compared to untreated knees Does not necessarily correlate with subjective clinical results Worse results with: 1. Concomitant Articular Cartilage Damage at time of arthroscopy 2. Chronic ACL deficiency 3. Mal-alignment Meniscal Repair 1885: Annandale documented first successful meniscus repair Popularized in 1970s by DeHaven and Wirth as alternative to meniscectomy (DeHaven, Orthop Trans, 1981; Wirth, CORR, 1981) Direct open suturing of peripheral tears Repair Techniques Open Inside-Out Outside-In All-Inside Meniscal Repair Maintain Meniscal Functions Load bearing Shock absorption Stress distribution Prevent degenerative changes Beneficial effects of meniscus preservation Partial vs Total Meniscectomy Repair vs. Partial Meniscectomy Difficult to compare Heterogeneity of tears Associated injuries ACL Articular Cartilage Patient Factors Recreational vs. professional Compliance with rehab So, repair should be even more beneficial

Repair vs Partial Meniscectomy Paxton systematic review 2011 Repair has higher re-operation rate (23% vs 4%) Higher in lateral meniscus Lower combined with ACL reconstruction (14%) Meniscal repair has not been definitively shown to reduce osteoarthritic changes when compared with partial meniscectomies BUT higher re-operation rate may be justified if there is a potential long term benefit of repair There is some evidence that meniscal repair does lead to better radiologic and subjective outcomes over the longterm. Meniscal Repair Indications 1. Young, active patient 2. Acute, symptomatic tears 3. Complete vertical longitudinal tear >10mm 4. Peripheral 10 30% (red-red and red-white zones) 5. Unstable tear 6. Stable knee 30 70% success rate in unstable knees Meniscal Repair Contraindications 1. Degenerative tear in older patients 2. White-white avascular tear 3. Stable, incomplete tears 4. Infectious, rheumatoid, collagen vascular disease 5. Non-compliance with rehab Growing Indications in young patients Devices evolving Techniques improving Role of Biologics? Sometimes an attempt to repair is better than the alternative Meniscal Repair Techniques ALL-INSIDE Inside-out Outside-in

All-Inside Advantages All arthroscopic, no open incisions Easy access to posterior meniscus Shorter operating time Relatively quick, easy insertion Implants necessary 4 generations: 1 st suture hooks 2 nd sutures attached to a peripheral bar (T-fix) required knot tying 3 rd rigid bioabsorbable devices (arrows, darts) 4 th suture devices, lower profile, allow tensioning (Fas-T-Fix, RapidLoc, Viper) 4 th generation suture devices show comparable biomechanical strength to open and inside-out techniques All-Inside Suture devices Clinical Results Hass 2005 80-90% clinical success at 2 years 91% with ACLR 80% isolated tears Barber 2008 83% clinical success at 3 years All-Inside d Complications Still risk of neurovascular damage Implant problems Technical problems Difficult to access anterior horn

Meniscal Repair Improved results combined with ACLR > 90% abundance of blood and growth factors in the joint relatively limited patient activity Less aggressive initial rehabilitation Intrinsic condition of the meniscus at the time of repair Augmenting isolated meniscal repair? Iatrogenic trauma to the surrounding synovium/fat pad microfracture in the notch/notchplasty growing interest in Biologics Stem Cells Animal Studies encouraging Smaller defects MSCs appear to localize and remain at the repair site Larger defects Require a scaffold loaded with MSCs Must pass through FDA regulatory pathway Early clinical studies Show potential for Increased meniscal volume after meniscectomy Decreased pain after meniscectomy Increased healing rate after repair def

Rehabilitation Partial Meniscectomy Accelerated rehab Immediate WBAT, FROM RTP 3-6 weeks Meniscal repair - controversial Isolated repair Protected weight bearing 50% PWB for 2 weeks, then advance to WBAT Brace locked in extension for 4 weeks Restricted hyperflexion/squatting for 4 weeks Rehabilitation With ACL Reconstruction No significant alteration in rehab protocol ROM and Weight bearing already limited by ACL in the early post-op period Rehabilitation BUT --- NWB for radial tears only exception Circumferential fibers disrupted Weight bearing distracts tear margins WBAT Immediately Weight bearing helps to compress circumferential fibers Reduces meniscus Stabilizes tear

conclusions A good history and physical exam with MRI can accurately diagnose meniscal injury Partial meniscectomy is one of the most commonly performed procedures today, but is not completely benign Meniscal Repair can preserve meniscal tissue and function when performed on the appropriate tear type and patient population All-Inside has become the preferred method for repair In combination with ACLR A meniscal repair has a better chance to heal Postoperative rehab protocol does not need to change with a repair For isolated meniscal repairs There is an increasing role for biologics The repair needs to be protected postoperatively