Personal data Surname & First name Occupational field Clinical Activity Surgical Activity Mortini Pietro, MD Professor of Neurosurgery MD, Specialist in Neurosurgery and ENT Surgery October 1 st 2008 - present Chairman, Neurosurgery and Radiosurgery Units October 1 st 2008 - present Professor of Neurosurgery Vita-Salute San Raffaele University, Milan November 1 st 2005 September 1 st 2008 Chairman Neurosurgery Unit Spedali Civili University Hospital, Brescia October 1 st 2005 September 1 st 2008 Consultant Neurosurgeon, Department of Neurosurgery 2002 Director Skull Base Surgery Section, Department of Neurosurgery 2001 Senior Active Staff member, Department of Neurosurgery 1996-2005 Consultant Neurosurgeon at the Department of Neurosurgery Lodi County Hospital, Lodi 1992-2000 Active Staff member, Department of Neurosurgery 1986 - Resident in Neurosurgery, Department of Neurosurgery University Hospital, Verona To date: 7374 micro neuro-surgical procedures performed as first operator and specifically 4.169 surgeries for intracranial tumours and vascular malformations, 2.087 transfenoidal procedures for sellar and suprasellar tumours, 1.014 spinal intradural and extradural procedures for tumours, 104 other procedures for hydrocephalus, infectious conditions and biopsy. Stereotactic Gamma Knife radiosurgical procedures on Perfexion equipment. Research Activity Publications Experimental Activities Published over 200 peer reviewed papers, mainly in refereed international scientific journals Director: Unit of Experimental Neurosurgery, San Raffaele Scientific Institute, Milan Pre-Clinical study on olfactory cell transplantation in spinal cord injuries (Grant of Regione Lombardia Autologous olfactory ensheathing cells transplantation in humans with spinal cord injuries: an international phase 2 multicentric clinical trial 2011/2012) Pre-clinical study on use of collagen scaffold in spinal cord and peripheral nerves injuries (PON #2 RINOVATIS) Page 1
Collaborations Ongoing Collaborations 2005 - present Department of Bioengineering - University of Lecce, Harvard Medical School - Boston (USA), Massachusetts Institute of Technology - Boston (USA) and Dept. of Neurology - Vita- Salute San Raffaele University Milano : research study on applications of collagen scaffolds for the treatment of nervous system injuries 2000 - present Institute of Medical Genetics University of Milano: research study on cytogenetic of skull base chordomas 1996 - present The Max Plank Istitut für Psychiatrie of Munchen (Germany): research study on pathology of the pituitary tumours 1992 - present The Chair of Maxillo-facial surgery of the University of Milan: research study on new surgical techniques for the treatment of cranio-facial malformation and craniofacial tumours 1992 - present Member of the Pituitary Unit (research unit officially recognized by the International Advisory Board of the Neuroscience Department - San Raffaele Scientific Institute) Clinical and Basic Research The George Washington University - Washington DC (USA) and Harvard Medical School, Boston (USA) Massachusetts Institute of Technology Boston (USA) Max-Planck-Institut für Psychiatrie, Munchen (Germany) Department of Neurology, Dept. of Neurosurgery, Dept. of ENT Surgery, Dept. of Endocrinology and Dept. of Pathology Vita/Salute San Raffaele University, Milan Department of Maxillofacial Surgery, Institute for Medical Genetics - University of Milan Department of Bioengineering - University of Lecce Committee Scientific Societies 1998 2005 Member of the Scientific Committee of the Italian Skull Base Society Other Membership Scientific Reviewer Member of the editorial board Congress of Neurological Surgeons (USA) European Society for Skull Base Surgery Italian Society for Skull Base Surgery Italian Society for Neurosurgery Pituitary (PITU), Editor-in-Chief Dr. Shlomo Melmed Journal of Neurosurgical Sciences Academic appointments and Teaching activity University 2015 Director, International University Master in Radiosurgery, Vita-Salute San Raffaele University School of Medicine, Milano 2015 Professor of neurophysiology, Course on Clinical application of Tissue Engineering DHITECH Technology and High-tech district (Lecce) 15/07/2011 to date Member of the Dean Committee of Vita-Salute San Raffaele University School of Medicine, Milano Page 2
Page 3 2010 to date Member of the Technical Commission - Cooperation Agreement between the University of Extremadura (Spain) and Vita-Salute San Raffaele University 2012 to date Member of the Technical Commission - Cooperation Agreement between the George Washington University (USA) and Vita-Salute San Raffaele University 17/01/2008 to date Director Residency Program in Neurosurgery, Vita-Salute San Raffaele University, Milan 10/01/2008 to date Full time professor, Vita-Salute San Raffaele University, Milan 2007 to date Clinical Professor of Neurosurgery The George Washington University Neurological Institute, Washington D.C. (USA) 2005-2008 Director Residency Program in Neurosurgery, University of Brescia 2005-2008 Full time professor, University of Brescia 2004-2005 Associate Professor of Neurosurgery, University of Brescia 2004-2005 Professor of Clinical Neuroanatomy, Vita-Salute San Raffaele University, Milan September 2004 Visiting Professor of Neurosurgery, Residency Program The George Washington University Neurological Institute, Washington D.C. (USA) October 2002 Visiting Professor of Neurosurgery, Residency Program The George Washington University Neurological Institute, Washington D.C. (USA) 2000-2002 Professor of Clinical Neurosurgery School of Medicine, Vita-Salute San Raffaele University, Milan 2000-2002 Professor of Surgical Anatomy of the Skull and the Brain School of Medicine, Vita-Salute San Raffaele University, Milan 2000-2002 Professor of Clinical Neurosurgery Residency Program in Neurosurgery, Vita-Salute San Raffaele University, Milan 2000 Tutor of Clinical Neurosurgery Residency Program in Neurosurgery, Vita-Salute San Raffaele University, Milan 1999 2000 Tutor of Neurosurgery at the School of Medicine and Residency Program University of Milan (Policlinic Hospital, San Raffaele Hospital, Sacco Hospital), University of Milano Bicocca/San Gerardo Hospital, Monza 1994-2000 Instructor of Neuroanatomy, Chair of Human Anatomy University of Milan 1992-1996 Instructor of Neuroanatomy Residency Program in Neurosurgery, Vita-Salute San Raffaele University, Milan 1990 1996 Professor of Neurosurgery School of Nursing - University Hospital in Verona and at San Raffaele University Hospital in Milan
Italian Ministry of Foreign Affairs Technology and Scientific Cooperation Unit (UST) 2015 Appointed as Scientific Attaché to the Embassy of Italy in Washington to promote formal links between Italian and American scientists and researchers, facilitating exchange initiatives and bilateral cooperation in the field of basic and applied biomedical research. Italian Ministry of Health 2010-2011 Member of the Joint Commission for cooperation between Italy and Malta 2011 Technical advisor for the Italian Ministry of Health for neurosurgery and tissue engineering Teacher in Post-graduate courses Professor in the following residency programs: General Surgery Anaesthesiology Paediatrics Neurology Organizer, instructor, lecturer in courses in National and International meetings. See enclosure for details Member of University Advisory Boards 2014 Commission for the appointment of associate professor - University of Bologna 2014 Commission for the appointment of associate professor - University of Verona 2011 Commission for the appointment of associate professor - University of Modena e Reggio Emilia 2010 Commission for the appointment of associate professor - University of Modena e Reggio Emilia 2009 Commission for the appointment of associate professor - University Cattolica del Sacro Cuore - Milan 2008 Commission for the appointment of associate professor University of Milan 2004 Commission for the appointment of associate professor - University of Medicine La Sapienza - Roma Education and training 2000 Diploma as ENT Surgery specialist with top marks - University of Milan, Milan Diploma as Neurological Surgery specialist with top marks - University of Verona, Verona 1986 First class medical degree Cum Laude and university honour - University of Parma, Parma 1980 High School Certificate, Classical Lyceum Page 4
Licensure and Professional Registrations 1986 Italian license to practice medicine and surgery with top marks - University of Parma, Parma 2014 Full registration with a licence to practice and entry on Specialist Register General Medical Council (UK) - GMC reference number 7480397 2005 Swiss licence to practice medicine and surgery as specialist in neurosurgery Postdoctoral Training Main courses attended IN ITALY 1997 8 th course in vascular surgery techniques, Milan 1996 International course in intra-operative cranial nerves monitoring, Italian Society for Skull Base Surgery, Parma Cranio-cervical junction surgery, Italian Society for Skull Base Surgery, Milan Trans-craniofacial approaches, Italian Society for Skull Base Surgery, Rome 1994 Lateral approaches to the skull base, Piacenza International Course in Transcranial Doppler, Montesilvano (PE, Italy) 4 th microsurgery workshop, Microsurgical Research Institute, Prato Italian Society for Neurosurgery Annual course, Abano (PD, Italy) 1989 Italian Society for Neurosurgery Annual course, Abano (PD, Italy) 1988 Cerebral arteriovenous malformations, Verona 1987 Cerebral aneurysms imaging, Verona Main courses attended OUTSIDE ITALY 1999 Congress of the American Association of Neurological Surgeons, New Orleans (USA) Antero-lateral approaches to tumours and aneurysms (Credit 4), Cavernous sinus surgery (Credit 2), Angiografically occult vascular malformations (Credit 2), Lateral skull base (Credit 2), Intracranial endoscopy (Credit 2) 1996 Course de chirurgie de la base du crâne (Prof Magnan), Marseille (France) 1996 5 th practical course in Microsurgery of the Skull Base (Prof. Fish), Klinik und Poliklinik fur Otorhinolaryngologie, Hals und Gesichtshchirurgie, Zurich (Switzerland) Workshop on the vertebral artery at the Hopital Lariboisière Paris (France). Supervisor Prof. P.B. George), Service de Neurochirurgie. 1992 International course on clinical neurosurgery (Prof. Samii), Hannover (Germany) Page 5
Focus Clinical and Research Educational Experiences Other personal skills and Competences 1999 International Fellowship. Research activity at the Minimally Invasive Surgery skull Base Training Center on microsurgical and endoscopic skull base approaches for clival tumours, vascular microsurgical and EC/IC by-pass training. Prof L. N. Sekhar, Department of Neurosurgery, The George Washington University Neurological Institute, Washington D.C. (USA) Training on surgical techniques for the control of vertebral artery in the treatment of vascular and tumoral pathologies of the skull base, the cranio cervical junction and the cervical spine. Prof. B.George, Department of Neurosurgery, Hôspital Lariboisiére, Paris (France) 1989 Experimental and clinical researches on calcium channel blockers in SAH related vasospasm. Prof N. Kassel. Training in Stereotactic radiosurgery, Prof. L. Steiner. Department of Neurosurgery, Virginia University, Charlottesville (USA). 1986 Training in Neurotrauma Prof. Miller D, Department of Neurosurgery, Western General Hospital, University of Edinburgh, Edinburgh (UK). 2008 Surgical instruments set for microsurgery of skull base. See: K. Storz catalogue Instruments according to Prof. P. Mortini Patents CA 2778238 Collagen Scaffold in nervous system regeneration - 2012 US20120214222 A1 Method for manufacturing a device for regenerating biological tissues, specifically for regenerating tissues of the central nervous system Mother tongue Italian Other languages Understanding Speaking Writing Listening Reading Spoken Interaction Spoken production English C 2 Proficient C 2 Proficient C 2 Proficient C 2 Proficient C 2 Proficient French C 2 Proficient C 2 Proficient C 2 Proficient C 2 Proficient C 2 Proficient Technical skills and competences Micro surgical procedures performed as first operator and specifically for skull base, brain and spine tumours and cerebrovascular disorders as indicated in Surgical activity Stereotactic Gamma Knife radiosurgical procedures since 1994 Page 6