Prof. Dr. med. Biljana Mihaljevic Chair of the Board for Studies in English, Belgrade University Faculty of Medicine (BUFM) Curriculum Vitae Name Prof. Dr.med. Biljana Mihaljevic Date of Birth 28. I. 1958 Belgrade, Serbia Address (institutional address): Belgrade University, Faculty of Medicine Dr Subotica 4/2oste Todorovica 2 11000 Belgrade, Serbia Phone: (381 11) 2 656 838 Fax:(381 11) 36 10 348 Web: www.mfub.bg.ac.rs Clinic of hematology, Clinical Center Serbia Koste Todorovica 2
11000 Belgrade, Serbia Phone/Fax: (381 11) 30 65 112 E-mail: hematologija@kcs.ac.rs Current Position Director, Clinic for Hematology, Clinical Center Serbia Professor of Internal Medicine, Belgrade University School of Medicine Chair of the Board for Studies in English, Belgrade University Faculty of Medicine (BUFM) Graduate Work, Thesis and Board Certifications 1976-1982, Belgrade University Faculty of Medicine,degree M.D 1984-1988, Oncology, BUFM, degree:mr Sci 1999, Doctorate, BUFM, degree:ph.d 1986-1991, Internal Medicine, BUFM, degree:specialist in Internal Medicine 2008, Hematology, BUFM (2008), degree:subspecialist in hematology Scientific Training 1991/92, British Council Research Fellowship, Prof Daniel Catovsky Laboratory, Royal Marsden Hospital, London, UK 2003, Visiting Proffesor, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland Professional Positions 1984-1988, medical doctor, Institute of Onoclogy and Radiology 1988-present, Clinic for hematology, Clinical Center Serbia 2008-present, Director, Clinic for Hematology, CCS 1994-2001, Assistent of Internal medicine, BUFM 2001-2008, Associated Professor of Internal medicine,bufm 2008-present, Full Professor of Internal medicine, BUFM 2015-present. Chair of the Board for Studies in English, BUFM Professional Affiliations Member of the Serbian Hematological Society, Serbian Medical Society 2002-2007, Secretary of the Hematological Society, Serbian Medical Society Founder and President of SLG, Serbian Lymphoma Study Group Member of the Advisory Board SMG, Srbian Multiple Myeloma Group Member of EHA. European Heamtology Association Member of ASH, Americal Society of Hematology
Other academic activities 2003-2005,Chair of CME Board, BUMF 2002-present, Memeber of the CME Board, Rectorate, University of Belgrade Mentor to more than 20 doctorates, masters, subspecialisations Presentations as Guest Speaker to about 100 talks on national and International Conferances, Symosiums, Workshops Scientific focus New drug development and Innovative therapeutical approaches in Lymphomas, Multiple Myeloma and Chronic Lymphocitic Leukemia. Prognostic factors and Molecular basis of non-hodgkins Lymphoma and Chronic Lymphocytic Leukemia Publications in internationally recognized haematological journals Publications (journals,selection) Blood, J Clin Oncol, Haematologica, Lancet Oncol., Med.Oncol., Biomed Pharmacother., Leuk Lymphoma, Clin Lymphoma Myeloma Leuk., Eur J Haematol, Thromb Res, World J Gastroenterol., BMC Immunol... Mihaljevic B, Vukovic V, Smiljanic M, Milic N, Todorovic M, Bila J, Andjelic B, Djurasinovic V, Jelicic J, Antic D. Single-center experience in the treatment of primary testicular lymphoma. Oncol Res Treat. 2014;37(5):239-42. Jaeger U, Trneny M, Melzer H, Praxmarer M, Nawarawong W, Ben Yehuda D, Goldstein D, Mihaljevic B, lhan O, Ballova V 1, Hedenus M 1, Hsiao LT 1, Au WY, Burgstaller S, Weidinger G, Keil F, Dittrich C, Skrabs C, Klingler A, Chott A 1, Fridrik MA, Greil R; AGMT-NHL13 Investigators.Rituximab maintenance for patients with aggressive B-cell lymphoma in first remission: results of the randomized NHL13 trial. Haematologica. 2015 Jul;100(7):955-63. Krajnović M, Jovanović MP, Mihaljević B, Anđelić B, Tarabar O, Knežević-Ušaj S, Krtolica K. Hypermethylation of p15 Gene in Diffuse - Large B-Cell Lymphoma: Association with Less Aggressiveness of the Disease. Clin Transl Sci. 2014 Oct;7(5):384-90. Andjelic B, Antic D, Jakovic L, Todorovic M, Bogdanovic A, Djurasinovic V, Bila J, Mihaljevic B. A single institution experience on 314 newly diagnosed advanced Hodgkin lymphoma patients: the role of ABVD in daily practice. Eur J Haematol. 2014 Nov;93(5):392-9. Markovic O, Popovic L, Marisavljevic D, Jovanovic D, Filipovic B, Stanisavljevic D, Matovina- Brko G, Hajder J, Matkovic T, Živkovic R, Stanisavljevic N, Todorović M, Petrovic D, Mihaljevic B. Comparison of prognostic impact of absolute lymphocyte count, absolute monocyte count, absolute lymphocyte count/absolute monocyte count prognostic score and ratio in patients with diffuse large B cell lymphoma. Eur J Intern Med. 2014 Mar;25(3):296-302 Davies A, Merli F, Mihaljevic B, Siritanaratkul N, Solal-Céligny P, Barrett M, Berge C, Bittner B, Boehnke A, McIntyre C, Macdonald D. Pharmacokinetics and safety of subcutaneous rituximab in follicular lymphoma (SABRINA): stage 1 analysis of a randomised phase 3 study. Lancet Oncol. 2014 Mar;15(3):343-52. Antic D, Petrovic N, Pelemis M, Stevanovic G, Perunicic M, Mihaljevic B. Invisible" primary cutaneous diffuse large B-cell lymphoma, leg type, as a cause of fever of unknown origin. J Clin Oncol. 2013 Jun 10;31(17):e276-9.
Markovic O, Marisavljevic D, Cemerikic-Martinovic V, Filipovic B, Radovanović S, Zdravković M, Stanisavljevic D, Mihaljevic B. c-flip does not correlate with response to immunochemotherapy treatment and outcome of patients with nodal diffuse large B-cell lymphoma.biomed Pharmacother. 2013 Jun;67(5):445-9. Matić IZ, Dorđević M, Dorđić M, Grozdanić N, Damjanović A, Kolundžija B, Vidović A, Bila J, Ristić S, Mihaljević B, Tomin D, Milanović N, Ristić D, Purić M, Gavrilović D, Cordero OJ, Juranić ZD. Dipeptidyl peptidase IV: serum activity and expression on lymphocytes in different hematological malignancies. Leuk Lymphoma. 2013 Smiljanic M, Milosevic R, Antic D, Andjelic B,.Djurasinovic V, Todorovic M, Bila J, Bogdanovic A, Mihaljevic B. Orbital and ocular adnexal MALT (Mucosa Associated Lymphoid Tissue) Lymphomas: a single center ten years expirience. Med Oncol,2013 Jaković Lj, Mihaljević B, Peruničić-Jovanović M, Bogdanović A, Andjelić B, Bumbaširević V. Prognostic significance of Bcl-2, Tumor Associated Macrophages, and Total Neoplastic and Inflammatory Lymph node Involvement in Advanced Stage Classical Hodgkin s Lymphoma. Onkologie. 2012;35(12):733-739. Karan-Djurasevic T, Palibrk V, Kostic T, Spasovski V, Nikcevic G, Srzentic S, Colovic M, Colovic N, Vidovic A, Antic D, Mihaljevic B, Pavlovic S, Tosic N. Mutational status and gene repertoire of IGHV-IGHD-IGHJ rearrangements in Serbian patients with chronic lymphocytic leukemia. Clin Lymphoma Myeloma Leuk. 2012;12(4):252-260. Markovic O, Marisavljevic D, Cemerikic-Martinovic V, Martinovic T, Filipovic B, Stanisavljevic D, Zivković R, Hajder J, Stanisavljevic N, Mihaljevic B. Survivin expression in patients with newly diagnosed nodal diffuse large B cell lymphoma (DLBCL). Med Oncol. 2012; 29(5):3515-3521 Todorovic M, Radisavljevic Z, Balint B, Andjelic B, Todorovic V, Jovanovic MP, Mihaljevic B. Increased angiogenesis-associated poor outcome in acute lymphoblastic leukemia: a single center study. Appl Immunohistochem Mol Morphol. 2012; 20(5):488-493 Andjelic BM, Mihaljevic BS, Jakovic LR. ABVD as the treatment option in advanced Hodgkin's lymphoma patients older than 45 years. Pathol Oncol Res. 2012; 18(3):675-680. Todorovic M, Balint B, Andjelic B, Stanisavljevic D, Kurtovic NK, Radisavljevic Z, Mihaljevic B. Outcome predictionof advanced mantle cell lymphoma by internationalprognostic index versus different mantle cell lymphoma indexes: one institutuion study. Med Oncol. 2012; 29(3):2212-2219. Antic D, Smiljanic M, Bila J, Jankovic S, Todorovic M, Andjelic B, Mihaljevic B.Hypothalamic dysfunction in a patient with primary lymphoma of the central nervous system., Neurol Sci. 2012;33(2):387-390. Andjelic B, Mihaljevic B, Todorovic M, Bila J, Jakovic L, Jovanovic MP. The number of lymphoma-associated macrophages in tumor tissue is an independent prognostic factor in patients with follicular lymphoma.. Appl Immunohistochem Mol Morphol. 2012; 20(1):41-46. Mihaljević BS, Todorović MR, Andjelić BM, Antić DA, Peruničić Jovanović MD. Unusual presentation of gastric plasmoblastic lzmphoma in HIV negative patinet. Med Oncol. 2012, 29 (2):1186-1189. Suvajdzic N, Djurdjevic P, Todorovic M, Perunicic M, Stojanović R, Novkovic A, Mihaljevic B.Clinical characteristics of patients with lymphoproliferative neoplasms in the setting of systemic autoimmune diseases. Med Oncol. 2012;29(3):2207-2211. Antic D, Mihaljevic B, Cokic V, Fekete MD, Djurasevic TK, Pavlovic S, Milic N, Elezovic I. Patients with early stage chronic lymphocytic leukemia: new risk stratification based on molecular profiling. Leuk Lymphoma. 2011;52(7):1394-1397. Jakovic LR, Mihaljevic BS, Perunicic Jovanovic MD, Bogdanovic AD, Andjelic BM, Bumbasirevic VZ. Leuk Lymphoma. 2011;52(10):1913-1919. Markovic O, Marisavljevic D, Cemerikic V, Perunicic M, Savic S, Filipovic, Mihaljevic B.Clinical and prognostic significance of apoptotic profile in patients with newly diagnosed nodal diffuse large B-cell lymphoma (DLBCL). Eur J Haematol. 2011;86(3):246-255. Lekovic D, Miljic P, Mihaljevic B.Increased risk of venous thromboembolism in patients with primary mediastinal large B-cell lymphoma. Thromb Res. 2010;126(6):477-480.
Mihaljevic B, Sternic N, Skender Gazibara M, Sretenovic A, Antic D, Terzic T, Kostic V.Intravascular large B-cell lymphoma of central nervous system - a report of two cases and literature review. Clin Neuropathol. 2010;29(4):233-238. Trifunovic D, Vujisic-Tesic B, Vuckovic M, Ostojic M, Ristic A, Bogdanovic A, Mihaljevic B, Andjelic B, Perunicic-Jovanovic M, Antonic Z.Multimodality imaging in the assessment of cardiac lymphoma presented as new-onset atrial fibrillation. Echocardiography. 2010;27(3):332-336. Sretenovć A, Antic D, Jankovic S, Gotic M, Perunicic-Jovanovic M, Jakovic L, Mihaljevic B. T- cell large granular lymphocytic (T-LGL) leukemia: a single institution experience. Med Oncol. 2010 ;27(2):286-290. Milosevic R, Todorovic M, Balint B, Jevtic M, Krstic M, Ristanovic E, Antonijevic N, Pavlovic M, Perunicic M, Petrovic M, Mihaljevic B. Splenectomy with chemotherapy vs surgery alone as initial treatment for splenic marginal zone lymphoma. World J Gastroeneterol. 2009;15(32):4009-4015. Sretenovic M, Colovic M, Jankovic G, Suvajdzic N, Mihaljevic B, Colovic N, Todorovic M, Atkinson MD. More than a third of non-gastric malt lymphomas are disseminated at diagnosis:a single center survey. Eur J Haematol. 2009;82(5):373-380. Juranić Z, Radić J, Konić-Ristić A, Jelić S, Mihaljević B, Stanković I, Matković S. Besu I, Gavrilović D. Humoral immunorractivity to gliadin and to tissue transglutaminase is present in some patients with multiple myeloma. BMC Immunol. 2008;9:22. Djunić I, Jevtović Dj, Ranin J, Salemović D, Tomin D, Mihaljević B. Srbian Lymphoma Study group (SLG): The prognosis of AIDS-related non Hodgkin s Lymphoma. Biomed Pharmacother. 2008;62(1): 12-15. Mihaljević B, Peruničić Jovanovića M, Jaković Lj, Sretenović A, Bošković D. Hodgkin lymphoma relapse in the uterine cervix 15 years after the initial cure. Med Oncol. 2008;25(2): 245-247. Jaković Lj, Mihaljević B, Peruničić-Jovanović M., Bogdanović A., Čemerikić Martinović V, Kravić T., Bumbaširević V The Expression of Ki67 and Bcl-2 in Hodgkin s lymphoma: Correlation with the International Prognostic Score and Bulky disease. A study by the Serbian Lymphoma Study Group (SLG). Med Oncol. 2007;24(1): 45-53. Todorović M, Pavlović M, Balint B, Kraguljac N, Mihaljević B, Bogdanović A, Elezović I, Bosković D, Čolović M Immunophenotype Profile and Clinical Characteristics In Patients with advanced Stage Mantle Cell Lymphoma, Med Oncol. 2007;24(4): 413-418. Mihaljević B, Jančić-Nedeljkov R., Čemerikić-Martinović V., Babić D., Čolović M. Ki 67 Proliferative marker in lymph Node Aspirates of Patients with Non-Hodgkin's with Non-Hodgkin's Lymphoma. Med Oncol. 2006;23(1): 83-89. Radojković M., Ristić S., Čolović M., Mihaljević B, Čemerikić-Martinović V Predictive value of prognostic indices in patients with follicular lymphomas. Med Oncol. 2006;23(4): 533-542. Mihaljević B, Nedeljkov-Jancić R, Vujicić V, Antić D, Janković S, Čolović N Primary extranodal lymphomas of gastrointestinal localizations: a single institution 5-yr experience. Med Oncol. 2006;23(2):225-235. Suvajdžić N, Stanojević-Milenković R, Mihaljević B, Tomašević Z, Čemerikić Z, Atkinson HDE. ALK negative T-cell anaplastic large cell l lymphoma associated with Systemic Lupus Erythematosus. Med Oncol. 2003;20(4):409-412. Mihaljević B, Čolović M., Cvetković D., Jovanović V. Solitary intracranial plasmocytomas. Oncol Rep. 1997;4(2): 439-441. Mihaljević B., Sretenović M., Jančić-Nedeljkov R., Petrović M. Acute megakaryoblastic leukemia with mediastinal tumor. Haematologia. 1996;27(3): 155-158. Mihaljević B., Donfird M., Jančić-Nedeljkov R., Jovanović V., Petrović M. Angioimmunoblastic lymphadenopathy (AILD) with benign course. Haematologia. 1996;28(1):21-25. Buccheri V., Mihaljević B., Matutes E., Dyer M, Mason D., Catovsky D, mb-1: A new marker for B-lineage lymphoblastic leukemia, Blood. 1993;82(3):853-857.