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Curriculum Vitæ Virginie PRULIERE ESCABASSE Date of birth: 4 th October 1969 Place of birth: Saint Maur des Fossés, France Nationality: French Married, with 4 children email: virginie.escabasse@chicreteil.fr Hospital Service d ORL et de chirurgie Cervico-Faciale du Pr André Coste Cystic Fibrosis Center Centre Hospitalier Intercommunal de Créteil 40 avenue de Verdun, 94000 Créteil Tel : 01 45 17 54 50 Teaching activity Faculté de médecine de Créteil 8 rue du Général Sarrail 94000 Créteil Research activity Unit INSERM 955 team 5 DHU ATVB ACADEMIC QUALIFICATIONS Baccalauréat school-laving certificate (majoring in science) (1987) Graduation, Créteil Faculty of Medicine (1995) Master s 2 in Biology and Physiology of Circulation and Respiration (respiration option) (Paris XII University, 2000) Doctor of Medicine (Paris XII University, 2004), with honours, silver medal Specialization certificate in Otorhinolaryngology (Paris XII University, 2004) Specialization certificate in Head and Neck Surgery (Paris XIII University, 2004) Certificate in Paediatric Audiophonology: otology option (Paris, 2004) PhD. in Respiratory physiology and pathophysiology (Paris XII University, 2008) (Thesis: Analysis and modulation of ion transport in human nasal epithelial cells. Role in the pathophysiology of sinonasal polyposis) Research Supervision Accreditation (Paris XII University, April 2012), with congratulations HOSPITAL AND TEACHING HOSPITAL POSITIONS Hospital resident, Paris (1995-2004) including 3 years secondment for full-time research work: Master s 2, with a grant from the French Pneumology Society (SPLF) PhD (2 years) with a grant from the AP-HP Paris Hospitals Board and French College of ORL and Head and Neck Surgery (CFORLCCF) Fellow, ORL and Head and Neck Surgery Dept, Créteil Intercommunal Hospital (Pr Coste): 1 st November 2005 to 30 th April 2009. 1

Hospital Practitioner, 1 st May 2009 to 31 st August 2013 Assistant Professor, ORL and Head and Neck Surgery Dept, Créteil Intercommunal Hospital (Pr Coste), since 1 st September 2013 FUNDAMENTAL RESEARCH Member of INSERM Unit 955 team 11, under Pr Goossens in Dr Fanen s group Team leader for ion transport and chronic inflammatory upper airway diseases Supervision of three Master s students (2010, 2013 and 2014) Principal investigator in the MUCO-BROCC study under a Clinical Research Contract signed in 2012 Application for an international patent for a novel cystic fibrosis diagnostic test, supported by INSERM Transfert CLINICAL RESEARCH Principal investigator and coordinator for the AVASMUC national hospital clinical research programme (aerosol therapy in cystic fibrosis). Funding: French Health Ministry (DGOS), 2013 Principal investigator and coordinator for a European project (France, Danemark, Sweeden, Germany) on sinus surgery combined with antibiotic therapy against Pseudomonas aeruginosa to delay its recurrence in upper and lower airways of Cystic Fibrosis Patients European guarantee fund (Horizon 2020) TEACHING ORL teaching, Créteil Medical Faculty Member of Docimology group, since 2011 Member of teaching assessment group, since 2011 ORL Check-List organisation officer, since2010 Examiner, structured clinical examinations, since 2010 Involvement in ORL postgraduate teaching, since 2010 In charge of postgraduate ORL pneumology courses in cystic fibrosis, University of Reims Involvement in teaching for the Inter-University Certificate course in Anatomic and physiological bases of rhinology therapies, directed by Pr Coste and Pr Bonfils (Paris XII and V Universities) In charge of ORL teaching for the Henri Mondor and Emile Roux nursing schools, since 2010 INVOLVEMENT IN HOSPITAL AND UNIVERSITY STRUCTURES Assessor of The ENT, Ophtalmology and Maxillofacial National Comity since 2016 Member of The Ear Nose and Throat National University Comity since 2015 Member of the management council of the Créteil Faculty of Medicine, since March 2013 Manager of the Créteil Hospital specialized surgery Functional Unit, since 2013 Member of the Créteil Hospital medical staffing commission, since 2013 Member of the French ENT and Head and Neck Surgery Society (SFORL) 2

Member of the French College of ENT and Head and Neck Surgery (CFORLCCF) Member of the French Rhinology Association (AFR) Board member of the French Cystic Fibrosis Society (SFM) Member of the SFM Research Group for Aerosols in Cystic Fibrosis (GRAM), since 2010 Member of the French Pneumology Society (SFP) Aerosol Therapy Research Group (GAT), since 2012 Since 2011, director of the ENT and Cystic Fibrosis work-group, set up by the French Cystic Fibrosis Society (SFM) and the Vaincre la Mucoviscidose association to improve ENT management in cystic fibrosis, draw up guidelines and design clinical research projects. Coordinator of the SFORL guidelines "Indications f o r a n d p r i n c i p l e s o f e n d o s c o p i c e n d o n a s a l m e d i a l m e a t o t o m y (2011) Coordinator of the SFORL guidelines "Indications f o r a e r o s o l t h e r a p y i n c h r o n i c r h i n o s i t i s (2014) Consultant to the French Health Authority (HAS) for radiology price-coding in ENT (2011) Consultant to national health insurance office (CNAMTS) for the price-coding of nasal, pharyngeal and laryngeal flexible endoscopy (2011) INVOLVEMENT IN SCIENTIFIC JOURNALS AND COMMITTEES Referee for The Laryngoscope Consultant to the Clinical Research and Innovation Office of Bordeaux University Hospital Consultant to the Belgian Association for the Fight against Cystic Fibrosis (ABLCM) Consultant to the Vaincre la Mucoviscidose association, assessing clinical and fundamental research projects PUBLICATIONS 41 publications: SIGAPS (scientific publications retrieval, management and analysis system) score, 372 3

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