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The David B. Levine, MD HSS Spine Symposium June 10, 2016 Provided by the Hospital for Special Surgery Spine Service and the Office of Continuing Medical Education Overview Care of the patient with cervical spine pathology requires familiarity with ever evolving modern instrumental techniques, implants, and surgical experience that may not be reported clearly or succinctly in peer-reviewed literature. Current research shows an increasing interest in cervical degeneration disease and cervical deformity, as well as techniques to manage and treat these conditions. However, many surgeons who evaluate and treat cervical spine disorders are not exposed to the latest modalities. The David B. Levine, MD Spine Symposium will allow course participants to address these topics through didactic lectures, panel discussions, case presentations, and Q&A sessions. Target Audience This activity is targeted to spine surgeons. Physiatrists, neurosurgeons, physical therapists, chiropractors, primary care physicians, residents and fellows can also benefit from this activity. Learning Objectives HSS professional education activities are intended to improve the quality of patient care and safety. At the completion of the course, the participant should be able to: Identify when to appropriately refer patients to complex spine specialists, such as cervical deformity surgeons, and be able to do so when appropriate. Describe the impact cervical spine deformity has on a patient s quality of life and relate the importance of addressing cervical spine deformity in a treatment plan. Describe best practices and the latest evidence-based techniques and treatment options conducted by experts for complex cervical spine disorders, such as comorbid cervical pathology with another spine segmented disease. Evaluate symptoms and indications to determine if a patient is a surgical candidate, and be able to do so in practice as well as describe non-surgical intervention options, such as physical therapy and pain management techniques, for patients with cervical degenerative disc disease. Describe evidence-based parameters for cervical spine deformity, such as age-stratified radiographic normative and pathological correlates, and also describe normative vs. non-normative alignment across the age spectrum. Accreditation & Credit Designation Hospital for Special Surgery is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Hospital for Special Surgery designates this live activity for a maximum of 5 onsite and 5 online AMA PRA Category 1 Credit(s). Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Financial Disclosure Policy In accordance with the Accreditation Council for Continuing Medical Education s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of the activity directors, planning committee members, presenters, authors and staff involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control. It is the policy of Hospital for Special Surgery to request all financial relationships that activity directors, planning committee members, presenters, authors and staff have with commercial interests, but to disclose to the activity audience only the relevant financial relationships. Activity Co-Directors Matthew E. Cunningham, MD, PhD, has disclosed no relevant financial relationships. Han Jo Kim, MD, has disclosed no relevant financial relationships. Frank Schwab, MD, has disclosed no relevant financial relationships. Guest Faculty Christopher P. Ames, MD, has disclosed no relevant financial relationships. John A. Bendo, MD, has disclosed no relevant financial relationships. John Caridi, MD, has disclosed no relevant financial relationships. Samuel Cho, MD, has disclosed no relevant financial relationships. Eric Elowitz, MD, has disclosed no relevant financial relationships. Prof. Dr. med. Jürgen Harms, MD, has disclosed no relevant financial relationships. Joel M. Press, MD, has disclosed no relevant financial relationships. Themistocles Protopsaltis, MD, has disclosed no relevant financial relationships. Kris E. Radcliff, MD, has disclosed no relevant financial relationships. Sheeraz A. Qureshi, MD, has disclosed no relevant financial relationships. HSS Faculty Federico P. Girardi, MD, has disclosed no relevant financial relationships. Virginie Lafage, PhD, has disclosed no relevant financial relationships. Hospital for Special Surgery Office of CME staff and CME Committee members have no relevant financial relationships to disclose regarding this activity.

AGENDA Friday, June 10, 2016 8:45 am Registration/ Breakfast* 9:10 am Welcome* 9:15 am Cervical Degenerative Disease: Clinical Burden, Non-operative Management Joel M. Press, MD 9:25 am Update: Cervical Disc Arthroplasty John A. Bendo, MD 9:35 am MIS Cervical Fusion Techniques: What and How Eric Elowitz, MD 9:45 am MIS versus Open Fusion Techniques for the Treatment of Cervical Spondylosis: Which is Better? What Does the Literature Say? Sheeraz A. Qureshi, MD 9:55 am How Cervical Degeneration (and its Treatment) Can Lead to Cervical Deformity Kris E. Radcliff, MD 10:05 am The Evolution of C1-C2 Fusions: Current Best Practice Techniques Prof. Dr. med. Jürgen Harms, MD 10:15 am Q&A 10:35 am Break* 10:50 am What is the Normative Alignment of the Cervical Spine with Aging? John Caridi, MD 11:00 am What Are the Radiographic Parameters That Define Deformity in the Cervical Spine? Virginie Lafage, PhD 11:10 am Cervical Deformity and Disability: The Clinical Perspective Han Jo Kim, MD 11:20 am The Relationship Between Cervical Deformity and Thoracolumbar Deformity Themistocles Protopsaltis, MD 11:30 am Q&A 11:45 am Lunch* 12:30 pm Surgical Treatment of Cervical Deformity The Utility of Cervical Osteotomies Christoper P. Ames, MD 1:00 pm Q&A

1:10 pm Tips for Avoiding Latrogenic Cervical and Cervicothoracic Deformity Samuel Cho, MD 1:20 pm Complication Avoidance and Management in Complex Cervical Surgery Federico P. Girardi, MD 1:30 pm Q&A 1:45 am Break* 1:55 pm Case Discussions/Presentations Moderator: Han Jo Kim, MD Christoper P. Ames, MD Prof. Dr. med. Jürgen Harms, MD Federico P. Girardi, MD Themistocles Protopsaltis, MD Osteotomy in the Cervical Spine Cases Cervical Pedicle Subtraction Osteotomy and Realignment Cervical/Cervicothroacic Posterior Column Osteotomy and Realignment Cervical Spine Sagittal Realignment: Why Select Pedicle Subtraction Osteotomy at C7, T1, or T2? 3:30 pm Closing Remarks* * Not designated for AMA PRA Category 1 Credit(s).

FACULTY Activity Co-Directors Matthew E. Cunningham, MD, PhD Assistant Attending Orthopaedic Surgeon Assistant Scientist on the Clinical Scientist Track, Research Division Hospital for Special Surgery Assistant Professor of Orthopaedic Surgery Weill Cornell Medicine Han Jo Kim, MD Assistant Attending Orthopaedic Surgeon Co-director Spine Fellowship Hospital for Special Surgery Assistant Professor of Orthopaedic Surgery Weill Cornell Medicine Frank J. Schwab, MD Chief, Spine Service Attending Orthopaedic Surgeon Hospital for Special Surgery Professor of Orthopaedic Surgery Weill Cornell Medicine Guest Faculty Christopher P. Ames, MD Professor of Clinical Neurological Surgery and Orthopaedic Surgery Director of Spine Tumor & Spinal Deformity Surgery Co-director, Spinal Surgery and UCSF Spine Center Director, Spinal Biomechanics Laboratory University of California San Francisco San Francisco, CA John A. Bendo, MD Director, Spine Service Clinical Affairs Associate Professor of Clinical Orthopaedic Surgery NYU Hospital for Joint Diseases NYU School of Medicine John Caridi, MD Assistant Professor Department of Orthopaedic Surgery Department of Neurosurgery Icahn School of Medicine at Mount Sinai

Samuel Cho, MD Associate Professor Department of Orthopaedic Surgery Department of Neurosurgery Icahn School of Medicine at Mount Sinai Eric Elowitz, MD Associate Attending Neurological Surgeon Associate Professor of Clinical Neurological Surgery Weill Cornell Medicine Prof. Dr. med. Jürgen Harms, MD Spine Surgery Ethianum Klinik Heidelberg, Germany Joel M. Press, MD Vice President, External Relations Executive Medical Director Outpatient Physician Services Medical Director, Spine and Sports Rehabilitation Centers Rehabilitation Institute of Chicago Reva and David Logan Distinguished Chair of Musculoskeletal Rehabilitation Professor, Physical Medicine and Rehabilitation Feinberg School of Medicine Chicago, IL Themistocles Protopsaltis, MD Director of Orthopaedic Spine Service Bellevue Hospital Attending Surgeon NYU Langone Medical Center Attending Surgeon Hospital for Joint Diseases Assistant Professor Department of Orthopaedic Surgery New York University Langone Medical Center Kris E. Radcliff, MD Assistant Professor Rothman Institute Depatment of Orthopaedic Surgery and Neurological Surgery Thomas Jefferson University Rothman Institute Egg Harbor, NJ

Sheeraz A. Qureshi, MD Associate Professor, Orthopaedic Surgery Minimally Invasive Spinal Surgery Co-director, Spinal Surgery Fellowship Icahn School of Medicine at Mount Sinai HSS Faculty Federico P. Girardi, MD Attending Orthopaedic Surgeon Associate Scientist, Research Division Professor of Orthopaedic Surgery Weill Cornell Medicine Virginie Lafage, PhD Director of Spine Research

Hospital for Special Surgery gratefully acknowledges funding support in part from generous educational grants from: DePuy Synthes Hospital for Special Surgery gratefully acknowledges the following exhibitors: Baxter Healthcare Harvest Technologies K2M LDR Spine Medicrea Medtronic NuVasive Orthofix, Inc. Ulrich Medical USA Xtant Medical ZimmerBiomet

Notes to Participants: PROGRAM AND POWERPOINT PRESENTATIONS The Hospital for Special Surgery Office of Continuing Medical Education is an environmentally green CME operation. We no longer reproduce extensive paper-bound conference materials rather we distribute this booklet which you have received to take notes. All presentations and/or outlines will be captured and distributed exclusively to meeting participants via your HSS eacademy account. To access the PowerPoint Presentations, follow the below steps using Google Chrome (this may not work if you use another internet browser): 1. Visit the course page at http://hss.classroom24-7.com/account/course/1083 (you may be prompted to log in to your account). 2. Select Section 5, Click here to access PowerPoint Presentations (upon conclusion of the activity). EVALUATION AND CERTIFICATE In keeping with our green CME operation, we no longer print paper evaluations, but instead utilize an online evaluation module. As a reminder, only those who registered for this course and complete the program evaluation will receive credit. To access the evaluation and receive your certificate, follow the below steps using Google Chrome (this may not work if you use another internet browser): 1. Visit the course page at http://hss.classroom24-7.com/account/course/1083 (you may be prompted to log in to your account). 2. Select Section 3 Click here to enter Access Code (provided in on-site course program) and enter the Access Code 06102016 when prompted. 3. Select Section 4, Click here to complete On-Site Evaluation & Certificate. 4. Upon completing the course evaluation, a blue Get Your Certificate button will appear on the course page. You can also access this certificate at any time by clicking on My Account on top menu bar, then choosing My Certificates. For more information please contact: Wanda M. Napolitano Senior Events and Marketing Coordinator Education & Academic Affairs Hospital for Special Surgery Tel: 212.606.1812 e-mail: napolitanow@hss.edu

The David B. Levine, MD HSS Spine Symposium June 10, 2016 Notes:

The David B. Levine, MD HSS Spine Symposium June 10, 2016 Notes:

The David B. Levine, MD HSS Spine Symposium June 10, 2016 Notes:

The David B. Levine, MD HSS Spine Symposium June 10, 2016 Notes:

The David B. Levine, MD HSS Spine Symposium June 10, 2016 Notes:

The David B. Levine, MD HSS Spine Symposium June 10, 2016 Notes: