Outline AIDS & HIV in the Joshua Vest Epidemiologist Austin/ Health & Human Services Department Worldwide HIV/AIDS surveillance National Prevalence Trends Disparities Mortality Modes of exposure Risk factors / behaviors Pediatric University of Texas April 26, 26 1 2 Global estimates for adults & children end 23 Adults and children estimated to be living with HIV/AIDS as of end 23 People living with HIV/AIDS 4 million New HIV infections in 23 _ 5 million Deaths from HIV/AIDS in 23 _ 3 million North America 79 1.2 million Caribbean 35 59 Latin America 1.3 1.9 million Eastern Europe & Central Asia Western Europe 52 68 1.2 1.8 million East Asia & Pacific North Africa & Middle East 7 1.3 million 47 73 Sub-Saharan Africa 25. 28.2 million South & South-East Asia 4.6 8.2 million Australia & New Zealand 12 18 WHO WHO 3 4 HIV incidence worldwide 5 million people were infected with HIV in 23 4.2 million adults 7, children (<15 years old) Region Sub-Saharan Africa N. Africa & Middle East S. & S.E. Asia E. Asia & Pacific Latin America Caribbean E. Europe & C. Asia W. Europe N. America Oceania # of new infections-23 3. million 36 5 WHO 6 75 85 2 2 52 2 44 5 Hetero Hetero, IDU Hetero, IDU Hetero, IDU, MSM MSM, IDU, Hetero MSM, Hetero IDU MSM, IDU MSM, IDU, Hetero MSM Main modes of transmission 1
HIV/AIDS surveillance The on-going and systematic collection, analysis, interpretation, dissemination, and evaluation of population-based information about persons infected with HIV or diagnosed with AIDS How data are collected Active reporting (Texas) State and local health department surveillance personnel collect information by contacting health care practitioners and reviewing medical records in hospital and clinics 7 8 What data are collected? Demographic characteristics Sex, race/ethnicity, age Mode of exposure to HIV Opportunistic illnesses & immunologic status Supplemental information Prescription of antiretroviral & prophylactic therapies Use of medical & substance abuse treatment services Health insurance coverage Confidentiality All data is keep confidential and private Names and personal identifiers of both cases and physicians are not reported to CDC 9 1 Limitations HIV surveillance data only include persons who have been tested confidentially Not all states require HIV surveillance AIDS surveillance data only represent persons with last-state HIV disease Representativeness of data Data only include persons who have been tested, and may not be representative of all HIV-infected persons It is estimated that at least 2/3 of HIVinfected persons have been confidentially tested and would be included in the surveillance system 11 12 2
Uses of data Monitor the incidence & prevalence of HIV infection and AIDS, and HIV-related morbidity and mortality in the population Identify changes in trends of HIV transmission & identify populations at risk Target prevention interventions and evaluate their effectiveness Allocate funds for social and health services United States 85, 9, people living with HIV/AIDS 25% don t know they are infected 4, new HIV infections each year -CDC 13 14 15 16 17 18 3
State/Territory # of Cumulative AIDS Cases New York 155,755 California 128,64 Florida 9,233 Texas 59,772 New Jersey 45,237 Illinois 28,426 Pennsylvania 28,136 Puerto Rico 27,242 Georgia 26,8 Maryland 25,358 CDC-22 19 2 Texas Counties with >5, population Area Cumulative AIDS cases Travis 4,52 Bexar 4,438 Collin 383 Dallas 13,767 El Paso 1,417 Harris 22,4 Hidalgo 55 Tarrant 3,71 Texas 64,97 24 21 # of cases Number of new AIDS cases by year 7 6 5 4 3 2 1 24 23 22 21 2 1999 1998 1997 1996 1995 1994 1993 1992 1991 199 1989 1988 1987 1986 1985 1984 1983 22 Number of new AIDS & HIV cases, 24 Category Total Male Female White non- / Other Black non- <3 3-39 4-49 5+ AIDS 161 13 31 61 57 43 2 63 57 21 HIV 181 158 23 9 38 53 57 73 33 18 23 number 4 35 3 25 2 15 1 5 AIDS cases by race/ethnicity 199 1991 White non- / other Black non- 1992 1993 1994 1995 1996 1997 1998 1999 2 21 22 23 24 24 4
Rate of new AIDS cases by race/ethnicity Why use rates rate per 1, 25 2 15 1 5 199 1991 Black non- White non- / other 1992 1993 1994 1995 1996 1997 1998 1999 2 21 22 23 24 25 Just using the number of new cases can be misleading It does not account for differences or changes in total population size Rate = # of new cases of disease during a year divided by the total population 26 Rate of new AIDS cases by gender AIDS rates by sex & race/ethnicity rate per 1, 14 12 1 8 6 4 2 Male Female 199 1991 1992 1993 1994 1995 1996 1997 1998 1999 2 21 22 23 24 rate per 1, 12 1 8 6 4 2 21.3 96.8 Male 24.5 White, not /other Black, not 45.7 6.4 1.5 Female Travis Co. 24 27 28 Rate of new HIV cases HIV rates by race/ethnicity 35 8 rate per 1, 3 25 2 15 1 rate per 1, 7 6 5 4 3 2 Black non- White non- / other 5 1999 2 21 22 23 24 1 1999 2 21 22 23 24 Travis Co. 29 3 5
Cumulative HIV/AIDS by race/ethnicity, as of 24 Race/ethnicity American Indian / Alaskan Native Asian Black non- Native Hawaiian / Pacific Islander White non- Multiple race & unknown No. 1,44 9 18 1,364 2,72 2 Persons living with HIV infection 1983 First cases reported in 24 2,894 known living HIV positive individuals in Most likely much higher 31 32 Persons living with HIV Infection number of persons 35 3 25 2 15 1 5 1999 2 21 22 23 24 Source: HARS 33 People living with HIV infections by sex & race/ethnicity 23% 21% 56% 54% White non- /other Black non- Men n = 2,458 Women n = 436 Travis Co, 24 19% 27% 34 Living with HIV/AIDS by exposure category 24 Prevalence of HIV/AIDS by zip code, 24 41% 11% MSM 64% 11% IDU MSM & IDU 32% 27% 4% 1% Hetero Other/NIR Female n = 436 Male n = 2458 35 36 6
Proportions of AIDS cases, among adults & adolescents, by exposure category & year of diagnosis, % of cases 9 8 7 6 5 4 3 2 1 Men who have sex with men MSM & IDU Injection drug use 1988 1989 199 1991 1992 1993 1994 1995 1996 1997 1998 1999 2 21 22 23 24 Other / NIR Heterosexual 37 deaths per 1, 4 35 3 25 2 15 1 5 Age adjusted HIV/AIDS mortality rates 199 1991 1992 1993 1994 1995 1996 1997 1998 1999 2 21 22 23 Travis Co. 38 Age adjusted HIV/AIDS mortality rates* Other data sources rate 12 1 8 6 4 2 1991-1992 1993-1994 1995-1996 1997-1998 1999-2 21-22 * Rate per 1, White non- Black non- Travis Co. Use more than just HIV/AIDS surveillance data Use other data sources to: Monitor risk behaviors Track risk groups Track co-morbidities Track service needs 39 4 Past-year prevalence of substance use among adults Supplement to HIV & AIDS Surveillance Project Any illicit drug Marijuana Cocaine/crack Heavy alcohol Austin 21.3 18.8 4.6 7. Dallas 1.1 7.4 2.4 6.1 El Paso 8.2 6.1 1.1 4.9 Fort Worth 8.9 6.9 1.2 5. Houston 1.7 7.7 1.8 6. San Antonio 1.3 8. 5.5 8.3 Texas 9.4 7. 2. 5.7 Supplemental questionnaire to known HIV and AIDS cases in Centers for Disease Control & Prevention funded project administered by the Texas Department of Health Covers behaviors, risk factors and socioeconomic factors Source: Texas Commission on Alcohol and Drug Abuse, 2 41 42 7
percent % of HIV+ individuals with a diagnosed mental disorder 7 6 5 4 3 2 1 Syphilis Syphilis and other STDs are sensitive, early markers of behaviors associated with HIV transmission Syphilis increases transmission and acquisition of HIV Syphilis trends may provide an early warning of changes in sexual behaviors and HIV incidence Travis Co. HIV+ MSM IDU MSM/IDU Hetero Other Source: Supplement to HIV and AIDS Surveillance Survey 43 44 ratio of male:female cases Ratio of male to female P&S syphilis cases 2 18 17.3 16 14 14. 12 1 8 6 4.7 6. 6. 4. 4 2 1999 2 21 22 23 24 Living pediatric HIV/AIDS cases by race/ethnicity, 24 29.2% 16.7% White non- / other Black non- 54.2% N=24 Travis Co. 45 46 Mother s exposure category for pediatric AIDS/HIV cases, cumulative as of 12/31/23 Mother sex w/hiv/aids or Hemophiliac 16% Mother's risk unknown /other 19% Mother was IDU 51% Summary Decreasing rates of AIDS, and HIV? African Americans disproportionately affected by HIV/AIDS Modes of exposure are changing Report available at: www.ci.austin.tx.us/health/downloads/23.pdf Mother sex w/idu 14% n = 38 47 48 8