COLLACTIVE HELPS MATURE SKIN BUILD LIFT AND FIRMING CUSHION 60% 50% Number of deep wrinkles (%) 40% 30% 28% 20% ANTI-WRINKLE EFFECT * 10% -10% -20%

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Number of deep wrinkles (%) QUAL/FTE/122/h COLLACTIVE Marine Collagen & Elastin oligopeptides Skin anti-ageing & Hydration COLLACTIVE is composed of collagen and elastin oligopeptides in the same ratio as in the dermis (respectively 94% and 6% of the total proteins). COLLACTIVE combines the two main constituents of the extracellular matrix and has an anti-wrinkle synergic action: elastin fibres give the dermis suppleness that completes collagen fibres tensile strength. COLLACTIVE oligopeptides have a low molecular weight, making them soluble in aqueous phase and fully digestible. COLLACTIVE is ideal for nutricosmetics. - PROPERTIES - COLLACTIVE REINFORCES SKIN HYDRATION The moisturizing effect of COLLACTIVE is supported by a clinical study involving 44 women over 40 years old. The results show an increase of the entire epidermis hydration (+8%) after oral administration of COLLACTIVE for 3 months. COLLACTIVE HELPS MATURE SKIN BUILD LIFT AND FIRMING CUSHION COLLACTIVE collagen and elastin oligopeptides stimulate the biosynthesis of dermis main constituents to lift and tone slacking areas. 6 5 4 51% COLLACTIVE minimizes apparent lines and wrinkles as per the results of the clinical study (see graph). On D84, the skin was exposed to cold temperatures, which explain the weaker anti-wrinkle effect at this period. The results highlight the protective effect of COLLACTIVE against the harsh conditions in winter. 3 2 1-1 -2-3 28% ANTI-WRINKLE EFFECT * D28-19% D84 PROTECTIVE EFFECT Placebo Collactive

COLLACTIVE IS A POTENT ANTIOXIDANT TO FIGHT AGAINST FREE RADICALS COLLACTIVE has a full anti-ageing action with potent antioxidant properties: the structural constituents of the dermis are thus protected against environmental damage. COLLACTIVE antioxidant activity was also substantiated by ORAC test. 10 Protection against beta-caroten oxidation BHA COLLACTIVE COLLACTIVE delays skin ageing process by protecting the skin and stimulating its main structural constituents. T+2h - TECHNICAL INFORMATION - SPECIFICATIONS (guaranteed for each batch) Appearance fine creamy powder Internal Proteins Kjedhal 9 on crude product NF V 04-407 Hydroxyproline 6% on dry matter NF V 014-415 Moisture 1 on crude product NF V 04-401 Ashes 7% on crude product NF V 04-404 Bulk density 0.35 0.50 Internal Tapped density 0.45 0.60 Internal TVN 250mg/100g Internal ph (sol. 1) 5.5 7.5 Internal SOLUBILITY soluble in water ENERGY VALUE 360 kcal/100g STORAGE Packaging 20kg bag in box Shelf life 24 months Store in a dry area and keep away from light. Make sure the bag is closed air-tightly once it has been opened. Don t keep the solubilized product over 65 C or under 4 C more than 24 hours without any stabilizing agent.

- REGULATION DATA - the data below have value of certificate COMPOSITION Compound Protein hydrolyzates, fish* (fish skin) Citric acid monohydrate*** Flavour**** Source Incorporated quantity (% on dry matter) CAS # EC # **Fishing area: FAO 27 / 91079-91-3 293-481-3 Fermentation 1 5949-29-1 201-069-1 Identical to natural and natural 0.15 / / *of which 94% is Collagens, hydrolyzates 6% is Elastins, hydrolyzates **Main fish species: Cod (Gadus morhua), Saithe (Pollachius virens), Haddock (Melanogrammus aeglefinus) and Plaice (Pleuronectes platessa) ***Complies with Regulation (EC) No 231/2012 ****Complies with Regulation (EC) No 1334/2008 Flavouring components: flavouring substances, natural flavouring substances Carrier: maltodextrin Additives: anti-caking agent E504 (3.5%) LEGAL STATUS Food grade product intended to be used in food products and food supplements. Produced in accordance with Regulation (EC) No 852/2004 and No 853/2004 on the hygiene of foodstuffs, with sanitary approval number FR 62 667 125 CEE. BSE/TSE Is based on fish raw material only and cannot be affected by BSE/TSE. Is not manufactured with any BSE-related risk material from bovine, ovine or caprine species, as defined in decision 2000/418/EEC and regulation 999/2001 and its amendments. GMO According to European Regulations n 1829/2003 and 1830/2003 Is free from ingredients, additives, processing aids made of or derived from GMO. RESTRICTED SUBSTANCES Does not contain any of the CMR substances as defined in Regulation (EC) No 1907/2006 and Regulation (EC) No 1223/2009 (article 15). Does not contain any other SVHC (PBTs and vpvbs) in accordance with Regulation (EC) No 1907/2006. Does not fall into the scope of Regulation (EC) No 1272/2008. PESTICIDES Does not contain pesticides in accordance with Regulation (EC) No 396/2005. MRIs (maximum residue levels of pesticides) are not applicable to fish products.

HAZARDOUS SUBSTANCES Regularly checked according to a periodic control plan Complies with Regulation (EC) No 1881/2006 and its amendments Lead Max. 3 ppm mineralization + ICP-MS Cadmium Max. 1 ppm mineralization + ICP-MS Mercury Max. 0.1ppm mineralization + ICP-MS Dioxins Max. 3.5 pg/g (on fresh fish) High resolution GC/MS Sum of dioxins and dioxin-like PCBs Max. 6.5 pg/g (on fresh fish) High resolution GC/MS Ma Sum of PCB28, PCB52, PCB101, Max. 75 ng/g PCB138, PCB153 and PCB180 Inorganic arsenic Max. 1ppm mineralization + ICP-MS Melamine Max. 2.5 ppm MICROBIOLOGICAL DATA Guaranteed for each batch Total plate count Max. 10,000 CFU/g Petrifilm 3 M Enterobacteriaceae Max. 10 CFU/g AFR V08-054 Staphylococcus aureus Absent / 1g European Pharmacopoeia E.coli Absent / 1g European Pharmacopoeia Yeasts and moulds Max. 100 CFU/g AFR XP V08-059 Salmonella Absent / 25g NF EN ISO 6579 IRRADIATION complies with Regulations (EC) n 1999/2 and 1999/3 Is not irradiated. Is free from ingredients, additives, processing aids made with the help of irradiation system or exposed to atomic radiation. SOLVENT complies with consolidated version of European Directive 2009/32 Is free from processing made with the help of solvent apart from water. Is free from VOCs (volatile organic compounds) in accordance with Regulation (EC) No 1999/13 on the limitation of emissions of volatile organic compounds due to the use of organic solvents.

ALLERGENS Complies with Regulations (EC) n 1169/2011, Annex II Main allergens Presence in the product Crosscontamination Sulphur dioxide and sulphites at concentrations of more than 10 mg/kg or 10 mg/litre in terms of the total SO2 Peanut and products thereof Nuts, namely: almonds, hazelnuts, walnuts, cashews, pecan nuts, Brazil nuts, pistachio nut, macadamia or Queensland nuts, and products thereof Eggs and products thereof Fish and products thereof FISH 10 YES Molluscs and products thereof YES Crustaceans and products thereof YES Soybeans and products thereof Cereals containing gluten, namely: wheat, rye, barley, oats, spelt, kamut or their hybridised strains, and products thereof Milk and products thereof (including lactose) Sesame seed and derived products Lupin and products thereof Celery and products thereof Mustard and products thereof