Breakthroughs in Neurologic Therapies:

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Stanford Health Care presents the 6th annual Breakthroughs in Neurologic Therapies: restoring function to the nervous system November 20 21, 2015 Palace Hotel San Francisco, CA Sponsored by the Stanford University School of Medicine A Continuing Medical Education Conference

Overview Statement of Need This CME activity seeks to fulfill the educational needs of healthcare professionals who manage patients with neurologic conditions. The goal of the symposium is to address identified clinical challenges, to update practitioners on latest advances and best practices in the rapidly evolving field of neuroscience, and to assist practitioners in developing strategies to apply this knowledge to the diagnosis, treatment and/or referral of patients with neurologic diseases and disorders. Lectures with question and answer sessions, panels and case discussions will afford learners the opportunity to discuss practice dilemmas with the expert faculty. Target Audience This course is designed for physicians who specialize in primary care, neurology, interventional radiology, neurosurgery, physical medicine and rehabilitation, neuro-oncology, internal medicine, emergency medicine, family practice as well as nurses and allied health professionals who manage patients with neurologic diseases and disorders. Accreditation The Stanford University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Credit Designation Stanford University School of Medicine designates this live activity for a maximum of 12.50 AMA PRA Category 1 Credits TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. The California Board of Registered Nursing recognizes that Continuing Medical Education (CME) is acceptable for meeting RN continuing education requirements; as long as the course is certified for AMA PRA Category 1 credit(s) TM (rn.ca.gov). Nurses will receive a Certificate of Attendance following this activity that may be used for license renewal. Tell a colleague; to register online go to: cme.stanford.edu/neuro

Program Friday, November 20, 2015 7:30 8:00 am Registration 8:00-8:10 Welcome and Announcements Gregory Albers, MD and Frank M. Longo, MD, PhD 8:10-8:30 Latest Strategies for Preventing and Treating Alzheimer s Frank M. Longo, MD, PhD 8:30-8:50 Real World Approach to Cognitive Concerns Sharon J. Sha, MD, MS 8:50-9:10 When to Refer Patients for Spine Surgery Lawrence M. Shuer, MD 9:10-9:30 Management of Adult Spinal Deformity Atman Desai, MD 9:30-9:50 Q&A Discussion Moderator: Frank M. Longo, MD, PhD 9:50-10:10 Break 10:10-10:30 New Landmark Trials of Endovascular Therapy Gregory Albers, MD 10:30-10:50 Neurointerventional Stroke Management Jeremy J. Heit, MD, PhD 10:50-11:10 How to Diagnose And Manage Nontraditional Causes of Stroke Nirali Vora, MD 11:10-11:30 Stem Cell Treatments for Stroke and Spinal Cord Injury Gary K. Steinberg, MD, PhD 11:30-11:50 Q&A Discussion Moderator: Gregory Albers, MD 11:50-1:00 pm Lunch 1:00-1:40 Neuroimaging Challenge Nancy J. Fischbein, MD 1:40-2:00 Is it Demyelinating Disease? Jeffrey Dunn, MD, FAAN 2:00-2:20 Neuroimmunology Case Vignettes May Han, MD; Christopher B. Lock, MD, PhD; Keith Van Haren, MD 2:20-2:40 Q&A Discussion Moderator: Jeffrey Dunn, MD, FAAN 2:40-3:00 Break 3:00-3:20 Chronic Migraine and Medication Overuse Headache Nada Hindiyeh, MD 3:20-3:40 Refractory Migraine or Refractory Patient? Treatment Challenges Robert Cowan, MD, FAAN 3:40-4:00 The Role of Autonomic Testing in the Diagnosis of Neurological Disorders Safwan Jaradeh, MD 4:00-4:20 Staying Current in the Management of the Neurotrauma patient: Polytrauma System of Care Odette Harris, MD, MPH 4:20-4:40 Q&A Discussion Moderator: Robert Cowan, MD, FAAN 4:40 Adjourn Saturday, november 21, 2015 8:00-8:05 am Announcements Jaimie M. Henderson, MD 8:05-8:25 Therapies and Breakthroughs in Dystonia Laurice Yang, MD, MHA 8:25-8:45 Ataxia: A Diagnostic and Therapeutic Challenge in Movement Disorders Veronica E. Santini, MD, MA 8:45-9:05 Deep Brain Stimulation for Movement Disorders Jaimie M. Henderson, MD 9:05-9:20 Q&A Discussion Moderator: Jaimie M. Henderson, MD 9:20-9:35 Break 9:35-9:55 Surgery for Tumors of the Skull Base Griffith R. Harsh IV, MD, MBA 9:55-10:15 High-Grade Gliomas: New Insights and Emerging Therapeutic Strategies Michelle Monje, MD, PhD 10:15-10:35 Cyberknife Radiosurgery for Brain Tumors Steve D. Chang, MD 10:35-10:50 Q&A Discussion Moderator: Griffith R. Harsh IV, MD, MBA 10:50-11:10 Status Epilepticus Robert Fisher, MD, PhD 11:10-11:30 Laser Interstitial Thermal Ablation for Epilepsy Gerald A. Grant, MD, FACS 11:30-11:50 Responsive Neurostimulation for Epilepsy Casey Halpern, MD 11:50-12:05 Q&A Discussion Moderator: Casey Halpern, MD 12:05-1:30 pm Lunch 1:30-1:50 Role of Inpatient Psychiatry in Helping to Diagnose psychogenic Disorders John Barry, MD 1:50-2:10 The Neurologist's Role in Managing Brain Injury After Cardiac Arrest Karen G. Hirsch, MD 2:10-2:30 Update on Genetic Testing in Neuromuscular Disorders Jacinda Sampson, MD 2:30-2:50 New Paradigms in Neurostimulation Peter Tass, MD, PhD 2:50-3:30 Q&A Discussion Moderator: Jaimie M. Henderson, MD 3:30 Adjourn Program subject to change.

Faculty All faculty are affiliated with Stanford University School of Medicine unless otherwise noted Course Directors Gregory Albers, MD Coyote Foundation Professor of Neurology and Director, Stanford Stroke Center Jaimie M. Henderson, MD John and Jene Blume - Robert and Ruth Halperin Professor of Neurosurgery Director, Stereotactic and Functional Neurosurgery Co-Director, Neural Prosthetics Translational Laboratory FACULT Y John Barry, MD Professor of Psychiatry and Behavioral Sciences Steve D. Chang, MD Robert C. and Jeannette Powell Neurosciences Professor Co-Director, Stanford Cyberknife Program Director, Neurogenetics Program Director, Neuromolecular Innovation Program Robert Cowan, MD, FAAN Clinical Professor of Neurology and Division Chief, Headache Atman Desai, MD Clinical Assistant Professor of Neurosurgery Jeffrey Dunn, MD, FAAN Clinical Professor of Neurology and Division Chief, Clinical Neuroimmunology Director, Neurology Clerkship Nancy J. Fischbein, MD Professor of Radiology and, by courtesy, Neurology, Neurosurgery, and Otolaryngology-Head and Neck Surgery Robert Fisher, MD, PhD The Maslah Saul Professor in the Department of Neurology Division Chief, Epilepsy Center Gerald A. Grant, MD, FACS Associate Professor of Neurosurgery Vice Chair for Pediatric Neurosurgery Division Chief, Pediatric Neurosurgery Casey Halpern, MD Assistant Professor of Neurosurgery May Han, MD Assistant Professor of Neurology and Odette Harris, MD, MPH Associate Professor of Neurosurgery Director, Brain Injury Associate Chief of Staff, Polytrauma Director, Defense Veterans Brain Injury Center Associate Chief of Staff, Rehabilitation, Palo Alto Veteran Affairs Griffith R. Harsh IV, MD, MBA Professor and Vice-Chairman for Education of Neurosurgery Director, Brain Tumor Center Co-Director, Pituitary Center Associate Dean, Postgraduate Medicine Education Jeremy J. Heit, MD, PhD Clinical Instructor of Radiology, Neuroradiology and Interventional Neuroradiology Divisions Nada Hindiyeh, MD Karen G. Hirsch, MD Assistant Professor of Neurology and Division Chief, Neurocritical Care Safwan Jaradeh, MD Professor of Neurology and Division Chief, Autonomics Christopher B. Lock, MD, PhD Clinical Associate Professor of Neurology and Frank M. Longo, MD, PhD George E. and Lucy Becker Professor Chairman, Department of Neurology and Michelle Monje, MD, PhD Assistant Professor of Neurology and Jacinda Sampson, MD Clinical Associate Professor of Neurology and Clinical Director, Neurogenetics Program Veronica E. Santini, MD, MA Co-Director, Huntington's Disease and Ataxia Clinic Stanford Movement Disorders Center Sharon J. Sha, MD, MS Co-Director, Huntington s Disease and Ataxia Clinic Director, Memory Disorders Clinical Trials Program Director, Behavioral Neurology and Neuropsychiatry Fellowship Lawrence M. Shuer, MD Professor of Neurosurgery Vice Chair for Quality Improvement Gary K. Steinberg, MD, PhD Bernard and Ronni Lacroute-William Randolph Hearst Professor of Neurosurgery and the Neurosciences Chairman, Department of Neurosurgery Peter Tass, MD, PhD Consulting Professor of Neurosurgery Director of the Institute of Neuroscience and Medicine Neuromodulation, Juelich Research Center, Germany Chair of Neuromodulation, Cologne University, Germany Keith Van Haren, MD Assistant Professor of Neurology and Nirali Vora, MD Laurice Yang, MD, MHA Learning Objectives Evaluate and utilize current screening, diagnosis and/or management strategies for patients presenting with the following diseases and disorders in order to improve quality of care: Dementia Chronic Neuromuscular Disorders Migraine/ Headache Adult Spinal Epilepsy Deformity Psychogenic Stroke Disorders Movement Disorders Head Trauma Evaluate and treat patients with neurologic disorders using the most recent advances in: Neuroradiology Neuro-oncology Neuroimmunology Appropriately determine when patients should be referred for additional diagnostic and/or treatment of neurological disorders.

Registration Faculty Disclosure The Stanford University School of Medicine adheres to ACCME Essential Areas, Standards, and Policies regarding industry support of continuing medical education. Disclosure of faculty and commercial relationships will be made prior to the activity. VENUE INFORMATION Palace Hotel Hotel phone: 415. 512.1111 2 New Montgomery St San Francisco, CA, 94105 www.sfpalace.com Registration Please register early hotel and conference space are limited. Registration fee includes continental breakfast, lunch, course materials and certificate of attendance. Register online by visiting cme.stanford.edu/neuro. Our online registration process requires the use of MasterCard or Visa in order to complete payment. Registrations are confirmed with a confirmation number on the screen and via e-mail immediately following your online registration. Please print a copy of your confirmation for your records. If you prefer to pay by check, please call 650.497.8554 for assistance. Early Bird Discount After October 23, 2015 Physician $495 $645 Allied Health Professional $300 $345 Cancellation Policy Cancellations received on or before October 23, 2015 will be refunded, less a $75 administrative fee. No refunds will be made on cancellations received after that date. Please send cancellation requests to stanfordcme@ stanford.edu or call 650.497.8554. Stanford University School of Medicine reserves the right to cancel this program; in the event of cancellation, course fees will be fully refunded. Stanford University School of Medicine is fully ADA compliant. If you have needs that require special accommodations, including dietary concerns, please contact cassalcazar@stanford.edu or 650.724.5318, before October 23, 2015. ABOUT Stanford Health Care Stanford Health Care is known worldwide for advanced treatment of complex disorders in areas such as cardiovascular disease, cancer treatment, neurosciences, surgery and organ transplant. Consistently ranked among America s Best Hospitals by U.S. News and World Report, Stanford is internationally recognized for translating medical break throughs into care of patients. For more information, please visit stanfordhealthcare.org. For more information about Stanford School of Medicine Departments of Neurology and Neurosurgery, please visit: neurology.stanford.edu med.stanford.edu/neurosurgery Stanford Center for Continuing Medical Education 1070 Arastradero Road, Suite 230 Palo Alto, CA 94304 Phone: 650.497.8554 Email: stanfordcme@stanford.edu Web: cme.stanford.edu Accommodations A block of guest rooms has been reserved at the special Stanford CME rate of $240/night at the Palace Hotel. You are urged to make your reservations early. The cut-off date is October 20, 2015, or until the group room block is filled. After this date, rooms will be provided on a space-available basis only. To secure a reservation, we ask that you contact the hotel directly at 888.627.7196, or visit http://bit.ly/neurocme15 to reserve online. Please identify yourself as a member of this Stanford CME conference to receive the special rate if you choose to reserve via phone. By staying at the host hotel, you help Stanford meet its contractual obligations and keep registration fees reasonable. Parking and Transportation Valet parking is available at the Palace Hotel. The charge is $59.00 per day including in and out privileges. For other parking options, visit cme.stanford.edu/neuro. Consider utilizing public transportation during your visit to San Francisco. For Bay Area transportation information, please visit www.511.org. Questions For questions about the conference or registration, please contact Cassandra Alcazar, CME Conference Coordinator at 650.724.5318 or email cassalcazar@stanford.edu Tell a colleague; to register online go to: cme.stanford.edu/neuro

Stanford Health Care Stanford Center for Continuing Medical Education 1070 Arastradero Road, Suite 230 Palo Alto, CA 94304 NONPROFIT ORG. U.S. POSTAGE PAID PALO ALTO, CA PERMIT NO. 188 cme.stanford.edu/neuro Stanford Health Care presents the 6th annual Breakthroughs in Neurologic Therapies: restoring function to the nervous system November 20 21, 2015 Palace Hotel San Francisco, CA Sponsored by the Stanford University School of Medicine A Continuing Medical Education Conference