NQF-ENDORSED VOLUNTARY CONSENSUS STANDARDS FOR HOSPITAL CARE. Measure Information Form Collected For: CMS Voluntary Only

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Last Updated: Version 4.4a NQF-ENORSE VOLUNTARY CONSENSUS STANARS FOR HOSPITAL CARE Measure Information Form Collected For: CMS Voluntary Only Measure Set: Surgical Care Improvement Project (SCIP) Set Measure I#: SCIP- Performance Measure Name: Surgery Patients on eta-locker Therapy Prior to Arrival Who Received a eta-locker uring the Period escription: Surgery patients on beta-blocker therapy prior to arrival who received a beta-blocker during the perioperative period. The perioperative period for the SCIP Cardiac measure is defined as the day prior to surgery through postoperative day two (PO 2) with day of surgery being day zero. If the postoperative length of stay is 2 days, the measure evaluates the administration of more than one dose of a beta-blocker: the day prior to or the day of surgery and on postoperative day one (PO 1) or postoperative day two (PO 2) unless reasons for not administering the medication were documented. If the postoperative length of stay is < 2 days, the measure will evaluate the administration of the beta-blocker on the day prior to or the day of surgery only, unless reasons for not administering the medication were documented. Rationale: Concerns regarding the discontinuation of beta-blocker therapy in the perioperative period have existed for several decades. Shammash and colleagues studied a total of 140 patients who received beta-blockers preoperatively. Mortality in the 8 patients who had beta-blockers discontinued postoperatively (50%) was significantly greater than in the 132 patients in whom beta-blockers were continued. Hoeks and colleagues studied 711 consecutive peripheral vascular surgery patients. After adjustment for potential confounders and the propensity of its use, continuous beta-blocker use remained significantly associated with a lower 1-year mortality than among nonusers. In contrast, beta-blocker withdrawal was associated with an increased risk of 1-year mortality compared with nonusers. The American College of Cardiology/American Heart Association site continuation of beta-blocker therapy in the perioperative period as a class I indication, and accumulating evidence suggests that titration to maintain tight heart rate control should be the goal. Type of Measure: Process Improvement Noted As: An increase in the rate Numerator Statement: Surgery patients on beta-blocker therapy prior to arrival who receive a beta-blocker during the perioperative period. SCIP--1

Included Populations: Not applicable Excluded Populations: None ata Elements: eta-locker enominator Statement: All surgery patients on beta-blocker therapy prior to arrival. Included Populations: IC-9-CM Principal Procedure Code of selected surgeries (as defined in Appendix A, Table 5.10 for IC-9-CM codes). Excluded Populations: Patients less than 18 years of age Patients who have a Length of Stay greater than 120 days Patients enrolled in clinical trials Patients whose IC-9-CM principal procedure occurred prior to the date of admission Patients who expired during the perioperative period Pregnant patients taking a beta-blocker prior to arrival Patients with a documented Reason for Not Administering eta-locker- Patients with Ventricular Assist evices or Heart Transplantation (as defined in Appendix A, Table 5.26 for IC-9-CM codes) ata Elements: Admission ate Anesthesia Start ate Anesthesia End ate eta-locker Current Medication eta-locker uring Pregnancy irthdate Clinical Trial ischarge ate IC-9-CM Principal Procedure Code eath Reason for Not Administering eta-locker- Sex Risk Adjustment: No ata Collection Approach: Retrospective data sources for required data elements include administrative data and medical record documents. Some hospitals may prefer to gather data concurrently by identifying patients in the population of interest. This approach provides opportunities for improvement at the point of care/service. However, SCIP--2

complete documentation includes the principal or other IC-9-CM diagnosis and procedure codes, which require retrospective data entry. ata Accuracy: Variation may exist in the assignment of IC-9-CM codes; therefore, coding practices may require evaluation to ensure consistency. Measure Analysis Suggestions: This measure seeks to identify surgery patients who were on beta-blocker therapy prior to arrival that received a perioperative beta-blocker. Health care organizations can identify patients who were on beta-blocker therapy for an extended period of time and compare them to those who received beta-blockers perioperatively, or those who did not receive the medication due to other reasons, i.e., complications or early discharges. An additional step would be to correlate the post hospital stay period to the beta-blocker administration during the pre/perioperative period. This will allow health care organization to take appropriate steps to ensure that patients receive the necessary care to reduce the risk of cardiovascular complications in the postoperative period. Sampling: Yes, please refer to the measure set specific sampling requirements and for additional information see the Population and Sampling Specifications Section. ata Reported As: Aggregate rate generated from count data reported as a proportion. Selected References: elzberg H, Rivkind AI. Preoperative cardiac preparation. Chest. 1999;115:82S- 95S. PMI: 10331339. oersma E, Poldermans, ax JJ, et al, for the utch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography (ECREASE) Study Group. Predictors of cardiac events after major vascular surgery: role of clinical characteristics, dobutamine echocardiography. PMI:11308400. unkelgrun M, oersma E, Schouten O, Koopman-vanGemert AWMM, van Poorten F, ax J, Thomson IR, Poldermans. isoprolol and fluvastatin for the reduction of perioperative cardiac mortality and myocardial infarction in intermediate-risk patients undergoing non-cardiovascular surgery: a randomized controlled trial (ECREASE-IV). Ann Surg 2009 Jun; 249(6):921-926. Fleisher LA, eckman JA, rown KA, Calkins H, et al. ACC/AHA 2007 Guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Cardiovascular Evaluation for Noncardiac Surgery). J Am Coll Cardiol 2007; 50: e159-241. Goldman L. Noncardiac surgery in patients receiving propranolol. Case reports and recommended approach. Arch Intern Med 1981;141:193-6. Hoeks SE, Scholte Op Reimer WJ, van Urk H, et al. Increase of 1-year mortality after perioperative beta-blocker withdrawal in endovascular and vascular surgery patients. Eur J Vasc Endovasc Surg 2007;33:13 9. Manual of Medical Therapeutics. epartment of Medicine Washington University, School of Medicine, St. Louis, MO, GA Ewald and CR McKenzie editors. 28th Edition, 1995. PMI: 0000000. SCIP--3

McGory ML, Maggard MA, Ko CY. A meta-analysis of perioperative beta blockade: What is the actual risk reduction? Surgery. 2005 Aug;138(2):171-179. PMI: 16153424. Pasternack PF, Imparato AM, aumann FG, et al. The hemodynamics of betablockade in patients undergoing abdominal aortic aneurysm repair. Circulation. 1987;76(suppl 3, pt 2):III-1-7. PMI:3621532. Poldermans, oersma E, ax JJ, et al, for the ECREASE Study Group. The effect of bisoprolol on perioperative mortality and myocardial infarction in highrisk patients undergoing vascular surgery. N Engl J Med. 1999;24:1789-1794. PMI: 10588963. Shammash J, Trost JC, Gold JM, et al. beta-blocker withdrawal and mortality in vascular surgical patients. Am Heart J. 2001;141:148-153. PMI: 11136500. van Klei WA, ryson GL, Yang H, Forster AJ. Effect of beta-blocker prescription on the incidence of postoperative myocardial infarction after hip and knee arthroplasty. Anesthesiology 2009; 111:717-24. Yaeger RA, Moneta GL, Edwards JM, et al. Reducing perioperative myocardial infarction following vascular surgery. The potential role of beta-blockade. Arch Surg 1995;130(8):869. PMI:7632148. Yusuf S, Peto R, Lewis J, Collins R, et al. eta lockade during and after myocardial infarction: an overview of the randomized trials. Prog Cardiovasc is 1985; 27: 335-371. PMI: 2858114. SCIP--4

SCIP-: Surgery Patients on eta-locker Therapy Prior to Arrival Who Received a eta- locker uring the Period Numerator: Surgery patients on beta-blocker therapy prior to arrival who receive a beta-blocker during the perioperative period. enominator: All surgery patients on beta-blocker therapy prior to arrival. START Run cases that are included in the SCIP Initial Patient Population and pass the edits defined in the Transmission ata Processing Flow: Clinical through this measure. Variable Key: Surgery ays Postoperative LOS Clinical Trial = Y = N Anesthesia Start ate =UT Non-UT Value Surgery ays (in days) = Anesthesia Start ate Admission ate Surgery ays < 0 0 =Y eath =N IC-9-CM Principal Procedure Code On Table 5.26 None on Table 5.26 eta-locker =N Current Medication =Y H SCIP--5

H Sex =F eta-blocker uring Pregency =1,3 = M,U =2 Anesthesia End ate =UT Non-UT Value Postoperative LOS (in days) = ischarge ate Anesthesia End ate >=2 days Postoperative LOS <2 days eta-locker eta-locker Any=1,2 eta-locker None=3,4 Any=3,4 Any=1,2 E None=1,2 or Only=5 None=1,2 or Only=5 Reason for Not Administering eta-locker- Any= 3, 4 E In Numerator Population Reason for Not Administering eta-locker- Any=1,2 eta-locker None=1,2 or Only=5 Only=5 None=3,4 or Only=5 Reason for Not Administering eta-locker- None=3,4 Reason for Not Administering eta-locker- Any=1,2 Any=3,4 E Any=3,4 None=1,2 or Only=5 Will e Rejected Case Not In Measure Population In Measure Population STOP SCIP--6

SCIP-Cardiac (Card)-2: Surgery Patients on eta-locker Therapy Prior to Arrival Who Received a eta-locker uring the Period Numerator: enominator: Variable Key: Surgery patients on beta-blocker therapy prior to arrival who received a beta-blocker during the perioperative period. All surgery patients on beta-blocker therapy prior to arrival. Surgery ays, Postoperative LOS 1. Start processing. Run cases that are included in the Surgical Care Improvement Project (SCIP) Initial Patient Population and pass the edits defined in the Transmission ata Processing Flow: Clinical through this measure. 2. Check Clinical Trial a. If Clinical Trial is missing, the case will proceed to a Measure Category Assignment of and will be rejected. Stop processing. b. If Clinical Trial equals Yes, the case will proceed to a Measure Category Assignment of and will not be in the Measure Population. Stop processing. c. If Clinical Trial equals No, continue processing and proceed to Anesthesia Start ate. 3. Check Anesthesia Start ate a. If the Anesthesia Start ate is missing, the case will proceed to a Measure Category Assignment of and will be rejected. Stop processing. b. If the Anesthesia Start ate equals Unable To etermine, the case will proceed to a Measure Category Assignment of and will be in the Measure Population. Stop processing. c. If Anesthesia Start ate equals a Non Unable To etermine Value, continue processing and proceed to the Surgery ays calculation. 4. Calculate Surgery ays. Surgery ays, in days, is equal to the Anesthesia Start ate minus the Admission ate. 5. Check Surgery ays a. If the Surgery ays is less than zero, the case will proceed to a Measure Category Assignment of and will not be in the Measure Population. Stop processing. b. If the Surgery ays is greater than or equal to zero, continue processing and proceed to check eath. 6. Check eath a. If eath is missing, the case will proceed to a Measure Category Assignment of and will be rejected. Stop processing. SCIP--7

b. If eath equals Yes, the case will proceed to a Measure Category Assignment of and will not be in the Measure Population. Stop processing. c. If eath equals No, continue processing and proceed to IC-9-CM Principal Procedure Code. 7. Check IC-9-CM Principal Procedure Code a. If IC-9-CM Principal Procedure Code is on Table 5.26 the case will proceed to a Measure Category Assignment of and will not be in the Measure Population. Stop processing. b. If IC-9-CM Principal Procedure Code is not on Table 5.26 continue processing and check for eta-locker Current Medication. 8. Check eta-locker Current Medication a. If the eta-locker Current Medication is missing, the case will proceed to a Measure Category Assignment of and will be rejected. Stop processing. b. If the eta-locker Current Medication equals No, the case will proceed to a Measure Category Assignment of and will not be in the Measure Population. Stop processing. c. If the eta-locker Current Medication equals Yes, continue processing and proceed to Sex. 9. Check Sex a. If Sex is missing, the case will proceed to a Measure Category Assignment of and will be rejected. Stop processing. b. If Sex equals Female, continue processing and check eta-locker uring Pregnancy. i. If eta-locker uring Pregnancy is missing, the case will proceed to a Measure Category Assignment of and will be rejected. Stop processing. ii. If eta-locker uring Pregnancy equals 1 or 3, the case will proceed to a Measure Category Assignment of and will not be in the Measure Population. Stop processing. iii. If eta-locker uring Pregnancy equals 2, continue processing and proceed to Anesthesia End ate. c. If Sex equals Male or Unknown, continue processing and proceed to Anesthesia End ate. 10. Check Anesthesia End ate a. If the Anesthesia End ate is missing, the case will proceed to a Measure Category Assignment of and will be rejected. Stop processing. SCIP--8

b. If the Anesthesia End ate equals Unable To etermine, the case will proceed to a Measure Category Assignment of and will be in the Measure Population. Stop processing. c. If Anesthesia End ate equals a Non Unable To etermine Value, continue processing and proceed to the Postoperative Length Of Stay (LOS) calculation. 11. Calculate Postoperative LOS. Postoperative LOS, in days, is equal to ischarge ate minus Anesthesia End ate. 12. Check Postoperative LOS a. If Postoperative LOS is less than 2 days, continue processing and proceed to check eta-locker. b. If Postoperative LOS is equal to or greater than 2 days, continue processing and proceed to Step 15 and check eta-locker. 13. Check eta-locker a. If eta-locker is missing, the case will proceed to a Measure Category Assignment of and will be rejected. Stop processing. b. If any eta-locker equals 1 or 2, the case will proceed to a Measure Category Assignment of E and will be in the Numerator Population. Stop processing. c. If no eta-locker equals 1 or 2 or eta-locker only equals 5, continue processing and proceed to Reason for Not Administering eta-locker. 14. Check Reason for Not Administering eta-locker a. If Reason for Not Administering eta-locker is missing, the case will proceed to a Measure Category Assignment of and will be rejected. Stop processing. b. If any Reason for Not Administering eta-locker equals 1 or 2, the case will proceed to a Measure Category Assignment of and will not be in the Measure Population. Stop processing. c. If no Reason for Not Administering eta-locker equals 1 or 2 or Reason for Not Administering eta-locker only equals 5, the case will proceed to a Measure Category Assignment of and will be in the Measure Population. Stop processing. 15. Check eta-locker a. If eta-locker is missing, the case will proceed to a Measure Category Assignment of and will be rejected. Stop processing. b. If any eta-locker equals 1 or 2, continue processing and proceed to Recheck eta-locker. SCIP--9

c. If no eta-locker equals 1 or 2 or eta-locker only equals 5, continue processing and proceed to Step 18 and check Reason for Not Administering eta-locker. 16. Recheck eta-locker a. If any eta-locker equals 3 or 4, the case will proceed to a Measure Category Assignment of E and will be in the Numerator Population. Stop processing. b. If no eta-locker equals 3 or 4, continue processing and proceed to check Reason for Not Administering eta-locker. 17. Check Reason for Not Administering eta-locker a. If Reason for Not Administering eta-locker is missing, the case will proceed to a Measure Category Assignment of and will be rejected. Stop processing. b. If any Reason for Not Administering eta-locker equals 3 or 4, the case will proceed to a Measure Category Assignment of E and will be in the Numerator Population. Stop processing. c. If no Reason for Not Administering eta-locker equals 3 or 4 or Reason for Not Administering eta-locker only equals 5, the case will proceed to a Measure Category Assignment of and will be in the Measure Population. Stop processing. 18. Check Reason for Not Administering eta-locker a. If Reason for Not Administering eta-locker is missing, the case will proceed to a Measure Category Assignment of and will be rejected. Stop processing. b. If any Reason for Not Administering eta-locker equals 1 or 2, continue processing and proceed to Recheck eta-locker. c. If no Reason for Not Administering eta-locker equals 1 or 2 or Reason for Not Administering eta-locker only equals 5, the case will proceed to a Measure Category Assignment of and will be in the Measure Population. Stop processing. 19. Recheck eta-locker a. If any eta-locker equals 3 or 4, the case will proceed to a Measure Category Assignment of E and will be in the Numerator Population. Stop processing. b. If eta-locker only equals 5, continue processing and Recheck Reason for Not Administering eta-locker. 20. Recheck Reason for Not Administering eta-locker SCIP--10

a. If any Reason for Not Administering eta-locker equals 3 or 4, the case will proceed to a Measure Category Assignment of and will not be in the Measure Population. Stop processing. b. If no Reason for Not Administering eta-locker equals 3 or 4, the case will proceed to a Measure Category Assignment of and will be in the Measure Population. Stop processing. SCIP--11