The Business of Food as Medicine

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The Business of Food as Medicine EPEMED Webinar November 16, 2011 Scientia Advisors LLC 55 Cambridge Parkway, Suite 300E Cambridge, MA 02142 www.scientiaadv.com 2011 Scientia Advisors, LLC Boston San Francisco All All Materials copyrighted and cannot not be be used without explicit permission

Agenda Definitions What s driving the growth of this field? Examples of products Background data: market size and growth rate Examples: food companies doing business in Food as Medicine Examples: food companies making venture investments in Food as Medicine Scientia Advisors LLC 2

Definition of Functional Foods Let thy food be thy medicine, and thy medicine be thy food Hippocrates Functional Foods provide a health benefit beyond basic nutrition Examples:» They can enhance health & well-being (for example, assist in weight loss, reduce risk of disease)» They can enhance the ability to perform physically and/or mentally (athletic performance, memory and other cognitive functions)» They can help manage a chronic medical condition (diabetes, heart disease) - 3 - Do Not Distribute Without Explicit Permission

What s Driving the Growth of This Field? We used to be primarily concerned about increasing life span Quality X Length - 4 - Do Not Distribute Without Explicit Permission

Length of Live vs. Quality of Life We used to be primarily concerned about increasing life span Quality - 5 - X Length Do Not Distribute Without Explicit Permission

Life Span vs. Health Span Now there s growing interest in increasing health span Quality We fear this: living many years with decreased ability to function Length - 6 - Do Not Distribute Without Explicit Permission

Life Span vs. Health Span Now there s growing interest in increasing health span Quality We d rather enjoy good health until the end Length - 7 - Do Not Distribute Without Explicit Permission

Life Span vs. Health Span Now there s growing interest in increasing health span Quality We ll gladly pay to enjoy the difference Length - 8 - Do Not Distribute Without Explicit Permission

Examples of Functional Nutritional Ingredients Functional ingredients provide health benefits to vital systems of the body Brain Health Docosahexaenoic Acid (DHA) Promotes healthy brain/eye development in infants; also being studied in adults Gingko Biloba Studies suggest it may enhance memory/concentration Valerian Root Studies suggest it may treat sleeping disorders, epilepsy Bone/Joint Health Calcium Healthy bone formation/maintenance Glucosamine Mixed data: may be helpful in cartilage strengthening or treatment of arthritis Vitamins K & D Healthy bone formation/maintenance Heart Health Eicosapentaenoic Acid (EPA) Anti-inflammatory Beta-Glucans Reduces cholesterol (LDL) Phytosterols Reduces cholesterol (LDL) Gut Health Probiotics Restore regular intestinal flora Prebiotic Fibers Stimulate growth of intestinal flora Ginger Root Anti-diarrheal Examples of other Functional Ingredients with possible benefits Antioxidants (resveratrol, lutein, Coenzyme Q10, etc.) Anti-inflammatory, anti-cancer, pro-metabolic, others all under clinical investigation Soy Protein Reduce cholesterol; under investigation for various anti-cancer benefits Green Tea Extract Anti-cancer, insulin regulation, alleviating neurodegenerative disease benefits all under clinical investigation - 9 - Do Not Distribute Without Explicit Permission

US $B Worldwide Functional Foods Market The market is growing rapidly, and is geographically dispersed THE GLOBAL FUNCTIONAL FOODS MARKET: $204B 2008 TOTAL WW FUNCTIONAL FOODS MARKET: $204B $300 $250 $200 $204B 7%/yr $270B Asia-Pacific 33% ROW 8% Europe 15% US 44% $150 $100 2012 TOTAL WW FUNCTIONAL FOODS MARKET: $270B $50 ROW 7% $0 2008 2012 Asia-Pacific 32% US 45% Enabler Foods Foods Sports Nutrition Herbs & Botanicals Beverages Meal Replacements Other Supplements Vitamins & Minerals Europe 16% Source: Scientia Analysis, DataMonitor/Euromonitor, HighBeam IRI Data, Kalorama, Nutrition Business Journal 10

Examples of food companies growing their business of Food as Medicine 11

Abbott Nutrition Specific Medical Conditions Abbott s Interest in Medical Nutrition of Specific Disorders CANCER DIABETES WOUND HEALING SARCOPENIA KIDNEY DISEASE 12

Chr Hansen s R&D Investment in Probiotics Chr Hansen s Study of Probiotic Strains for Specific Diseases Chr Hansen is pursuing eight indication areas: Intestinal balance Diarrhea Antibiotic associated Traveler s Constipation Children s well-being Infant health Immune support Bacterial vaginosis 13

Chr Hansen s Growing List of Customers Customers Buying Chr Hansen s Probiotics 14

Revenue PepsiCo: Adding H&W to Its Core Business PepsiCo has steadily increased its portfolio of healthy snacks and beverages PEPSI S GOOD-FOR-YOU PRODUCTS $Bn $30 $20 $10 $0 $2.2 Source: Scientia Analysis, company reports, press releases and public data, Power of PepsiCo 2010 Scientia Advisors LLC 18%/ year $12.1 10%/ year $30 2000 2010 2020E 15 KEY TAKEAWAYS PepsiCo expanded the healthy food and beverage portfolio because rising awareness of health and wellness was putting pressure on the carbonated soft drink and salty snack businesses Pepsi s Good for You products have higher margins than salty snacks and carbonated soft drinks PepsiCo has considerable experience in multiple retail channels for snacks and beverages The existing distribution and marketing channels support the distribution of new healthy products

Nestle s Move into Personalized Nutrition Nestle s Investment in Personalized Nutrition Opened in January 2011 with plans to develop personalized nutrition products for specific diseases Prometheus specializes in treatments and tests for IBS, Crohn s disease, and cancer Nestle aims to become the world leader in health-science nutrition in 10 years 16

Examples of Companies Pursuing Food as Medicine From major CPG companies to ingredient manufacturers Various Personalized Nutrition Approaches 17

Big Food Companies And Venture Capital Many are now investing in H&W/nutrition focused funds Nutrition Capital Network lists these companies as investors: Scientia Advisors LLC 18

Summary and Conclusions The traditional food industry long defined their market as, Everyone who needs to eat Health & Wellness was viewed as a collection of unappealing niche markets But Health & Wellness is sustaining attractive growth rates Those niche markets are now looking increasingly attractive:» Better margins» Higher purchase rates per customer Major food companies are beginning to leverage their distribution channels and their existing brands to put Health & Wellness products on retail shelves Many food companies are also investing in venture funds primary goal: get an early look at innovation Scientia Advisors LLC 19

THANK YOU! Scientia Advisors LLC 20