Influenza A H1N1 Swine Flu Update:

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Influenza A H1N1 Swine Flu Update: Pandemic Influenza Planning for the Workplace Current as of August 2009 Georgia Tech OSHA Consultation Program This course does not necessarily reflect the views or policies of the U.S. Department of Labor, nor does mention of trade names, commercial products, or organizations imply endorsement by the U.S. Government. GTRI_B-1

Seasonal Flu Avian Flu Swine Flu Pandemic Flu Cause Virus strain changes every year. H5N1 is current virus strain Novel H1N1 is current virus strain Transmission Sneezing and coughing (droplets); surface contact Bird to bird; some bird to human (rare); secretions Sneezing and coughing (droplets); surface contact Severity 5-20% US population infected. >200,000 hospitalized 36,000 die 348 human cases, 216 deaths (Jan. 2008) 436 human cases, 262 deaths (July 1 2009) US: 43,771 confirmed cases, 353 deaths World: 134,503 cases, 816 deaths (July 30 2009) Target Population 5 years old and 65 years old Working population All specific at risk populations Immunity Some immunity Limited immunity No immunity Current Status Flu season is usually December March Limited human cases in 15 countries (as of 5/2009) Currently evolving WHO Phase 6 GTRI_B-2

Symptoms and Signs of H1N1 Suspected to be transmitted from large droplets (travels <6 ft) Contact with contaminated surfaces is another possible source of transmission Similar to the symptoms of regular human flu: Fever (90%), cough (84%), sore throat (61%), body aches, headache, chills, or fatigue. Some reports of diarrhea (26%) or vomiting (24%). May cause a worsening of underlying chronic medical conditions. GTRI_B-3

Confirmed and Probable cases of H1N1 GTRI_B-4

GTRI_B-5

Current Epidemiologic Status: H1N1 The gallimaufry virus a hodgepodge stew that s been brewing: Part Avian, part human, part swine virus Sloppy virus that doesn t proofread it s mistakes Mix it all up in the belly of a pig Scientists are closely monitoring genetic changes/shifts to project future mutations Special attention is being given to the Southern Hemisphere that is now experiencing winter Image from CDC Provide clues what will happen in the fall GTRI_B-6

Seasonal Flu Avian Flu Swine Flu Pandemic Flu Cause Virus strain changes every year. H5N1 is current virus strain Novel H1N1 is current virus strain Unknown, highly pathogenic virus (now H1N1) Transmission Sneezing and coughing (droplets); surface contact Bird to bird; some bird to human (rare); secretions Sneezing and coughing (droplets); surface contact Unknown probably droplet, contact, possibly aerosol Severity 5-20% US population infected. >200,000 hospitalized 36,000 die 348 human cases, 216 deaths (Jan. 2008) 436 human cases, 262 deaths (July 1 2009) US: 43,771 confirmed cases, 353 deaths World: 134,503 cases, 816 deaths (July 30 2009) (Past Pandemics) 30% US population infected 8,300 to 500,000 deaths in US; 700K to 40 million worldwide Target Population 5 years old and 65 years old Working population All specific at risk populations All; in past primarily 18-35 years old Immunity Some immunity Limited immunity No immunity No immunity Current Status Flu season is usually December March Limited human cases in 15 countries (as of 5/2009) Currently evolving WHO Phase 6 Pandemic GTRI_B-7

Is a Pandemic Vaccine Available? A vaccine to protect people from pandemic flu is not available now (~ 6-8 months after start) Potentially available mid-october 2009 Likely first recipients: Pregnant women; household contacts/caregivers of children < 6 months age; healthcare workers; young individuals (6 mo-24 yrs); those with underlying health conditions ~159 million doses The best protection is to practice healthy hygiene to stay well now and during a flu pandemic Department of Health and Human Services announced May 22, 2009: Approximately $1 billion will be used for clinical studies to take place over the summer to develop an H1N1 vaccine. Will be used for pre-pandemic influenza stockpile. Contact www.hhs.gov for most up to date information. GTRI_B-8

Current Status Where are we now? What preparation has been done so far? Federal level State level What available tools do we need to understand to prepare better at the local level? GTRI_B-9

Confirmed & Reported Current Status As of 1 July 2009 H5N1 (Influenza Type A bird ) Bird to human (non-sustained) 15 countries 436 cases 41 cases for 2009 262 deaths 12 deaths for 2009 ~60% case fatality As of 30 July 2009 H1N1 (Influenza A swine ) Human to human (sustained) Global 134,503 cases 816 deaths <1% case fatality unprecedented speed Compare to case fatality rate of 1918 Pandemic: ~4% GTRI_B-10

U.S. Government and WHO: A Comparison U.S. Government Stages WHO Phases 0 New domestic animal outbreak in atrisk count Inter-pandemic phase New virus in animals, human cases Low risk of human cases 1 Higher risk of human cases 2 1 Suspected human outbreak overseas Pandemic Pandemic Alert alert No or very limited human-tohuman transmission 3 2 Confirmed human outbreak overseas 3 Widespread outbreaks overseas 4 First human case in North America 5 Spread throughout U.S. New virus causes human cases Pandemic Current Status Evidence of increased humanto-human transmission 4 Evidence of significant humanto-human transmission 5 Efficient and sustained humanto-human transmission 6 GTRI_B-11

Recommendations for the Pandemic Period If an influenza pandemic begins in the United States or another country: State and local responsibilities: Implement enhanced surveillance to detection first cases Enhance all influenza surveillance components Communicate surveillance data needs For more information: http://www.hhs.gov/pandemicflu/plan/pdf/s01.pdf GTRI_B-12

Recommendations for the Pandemic Period HHS responsibilities: Provide technical support Update case definitions and guidance for laboratory testing and enhanced surveillance Assist state and local health departments Analyze influenza surveillance data For more information: http://www.hhs.gov/pandemicflu/plan/pdf/s01.pdf GTRI_B-13

Monitoring for Influenza Assign responsibility for monitoring developments with the national and state public health advisories. Develop a plan to monitor for pandemic influenza in the population served. Develop a system to report unusual cases of influenza-like illness and deaths to local health authorities. China s approach: thermal Source: www.chinaview.cn (April 28, 2009 Xinhua/AFP Photo) For more information: http://www.hhs.gov/pandemicflu/plan/pdf/s01.pdf GTRI_B-14

WHO: Surveillance 16 July 2009 (WHO) & 24 July 2009 (CDC): Discontinued reporting of individual confirmed and probable cases CDC: Sustained community transmission = testing and confirmation of every individual case extremely difficult Strategy: Severe or fatal clusters Hospitalization Change in transmission pattern Newly affected countries Strategy (weekly): Hospitalizations Deaths Use of Traditional Flu Surveillance System to track H1N1 and seasonal flu activity and trends Specimen testing Physician network Hospitalizations GTRI_B-15

What Should I Do? (as of Aug 2009) Most Likely: Resolve at home Remain home 24 hours after fever-free (100 ) without reducers (http://www.cdc.gov/h1n1flu/business/guidance/) More stringent guidelines and longer periods of exclusion for example, until complete resolution of all symptoms may be considered for people returning to a setting where high numbers of highrisk people may be exposed (including nursing homes). (http://www.cdc.gov/h1n1flu/guidelines_infection_control.htm) Guidance is same even if using anti-viral meds GTRI_B-16

Lessons Learned 6/4/09 Review by: Robert Wood Johnson Foundation and Center on Biosecurity 1. Investments in pandemic planning and stockpiling antiviral medications paid off. 2. Public health departments did not have enough resources to carry out plans. 3. Response plans must be adaptable and science-driven. 4. Providing clear, straightforward information to the public -- from the president on down to local officials -- was essential for allaying fears, building trust, and acting to contain the spread of the virus. 5. School closings have major ramifications for students, parents and employers. 6. Sick leave and policies for limiting mass gatherings were also problematic. 7. Communication between the public health system and health providers was not well coordinated, with many private clinicians not receiving guidance on a timely basis. 8. The World Health Organization pandemic alert phases caused confusion. 9. International coordination was more complicated than expected. GTRI_B-17

www.flu.gov www.cdc.gov/h1n1flu KEY RESOURCES www.flu.gov/plan/individual/index.html (family readiness checklist; multiple languages available) www.cdc.h1n1flu/espanol (multiple resources in Spanish) www.osha.gov/publications/osha3327pandemic.pdf www.osha.gov/pulibcations/osha_pandemic_health.pdf www.osha.gov/publications/exposure-risk-classificationfactsheet.html www.osha.gov/publications/protect-yourself-pandemic.html www.osha.gov/publications/protect-yourself-pandemicrespiratory.html www.accessdata.fda.gov/scripts/h1n1flu/#mask (FDA listing of fraudulent products, claims, websites) GTRI_B-18

Contact Information Hilarie Schubert Warren, MPH Industrial Hygienist Health Sciences Branch Georgia Tech Research Institute 430 10th St NW, North Building Atlanta, GA 30332-0837 PHONE (404) 407-6255 FAX (404) 407-9256 email: hilarie@gatech.edu website: www.oshainfo.gatech.edu Information Provided under OSHA Susan Harwood Grant #SH-16620-07-60-F-13 GTRI_B-19 Filename - 19