Joint meeting ADWP & SAAWP November 2016, Paris, France

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Preliminary Programme 09 November - ADWP Educational 10:00-10:30 Welcome & coffee 1 st session Connective tissue diseases Chair: David Kiely & Renate Arnold 10:30-10:50 How do we make HSCT for SSc safer? EBMT Guidelines Dominique Farge 10:50-11:10 Immune reconstitution and mechanistic aspects Maria-Carolina Oliveira 11:10-11:30 Gene and cell therapies for systemic autoimmune diseases Attilio Bondanza 11:30-11:50 Future protocols and trials in SSc and SLE. Tobias Alexander 2 nd session Crohn s session Chair: John Snowden & Elena Ricart 11:50-12:10 CD guidelines/current recommendations Montserrat Rovira 12:10-12:30 Immune reconstitution in Crohn s disease TBA 12:30-12:50 What comes after ASTIC/ what next trial TBA 12:50-13:00 EBMT data on Crohn s disease Cristina Castilla Llorante Charlotte Brieley 13:00-14:00 Lunch

3 rd session Neurological diseases Chair: Paolo Muraro & Hans Hagglund 14:00-14:20 Choice of patient in MS Basil Sharrack 14:20-14:40 Choice of conditioning regimen in MS Riccardo Saccardi 14:40-15:00 Chronic inflammatory demyelinating polyneuropathy (CIDP) Joachim Burman 15:00-15:30 Canadian experience for ASCT in Multiple Sclerosis, Myasthenia Gravis, and Stiff Person Syndrome Harold Atkins 15:30-16:00 Coffee break 4 th session Rare indications Chair: Tobias Alexander & Majid Kazmi 16:00-16:20 Vasculitis and Polymyositis/Dermatomyositis Thomas Daikeler 16:20-16:40 HSCT and Cellular Therapy in immune cytopenia Nicola Cooper 16:40-17:00 HSCT for autoinflammatory paediatric diseases Mario Abinun 17:00-17:20 Close and Discussion

10 November - Business meetings 08:30-10:30 Business meetings 10:30-10:45 Coffee break 10:45-12:30 Joint Educational session 5 th session Conditioning regimens and post-transplant care Chair: John Snowden & Regis Peffault de Latour 10:45-11:05 New conditioning regimens what can the ADWP and the SAAWP learn from each other? Jakob Passweg 11:05-11:25 Vaccinations in aplastic anaemia and autoimmune diseases Per Ljungman 11:25-11:35 Secondary autoimmune diseases following HSCT Paul Miller 6 th session ATG Chair: Carlo Dufour & Tobias Alexander 11:35-11:55 Mechanism of Action Phillip Scheinberg 11:55-12:15 Role of ATG in RIC Fabio Ciceri 12:15-12:35 Overlap Syndromes Maurizio Miano 12:45-14:00 Lunch

10 November - SAAWP Educational 14:00-14:15 Opening Carlo Dufour, Regis Peffault de Latour 7 th session Chair: Carlo Dufour, Regis Peffault de Latour 14:15-14:45 Physiopathology of idiopathic aplastic anemia Shahram Kordasti 14:45-15:00 Questions Controversy I: Do I consider somatic mutations in AA as MDS? Chair: Shahram Kordasti 15:00-15:15 Yes Austin Kulasekararaj 15:15-15:30 No Gérard Socié 15:30-16:00 Debate 16:00-16:30 Coffee break 8 th session Chair: Gérard Socié 16:30-17:00 First line treatment Judith Marsh 17:00-17:15 Questions

Controversy II: Do I offer transplantation for young patients (<20 years) with classic PNH and a matched available sibling donor? Chair: Antonio Risitano 17:15-17:30 Yes Hubert Schrezenmeier 17:30-17:45 No Regis Peffault de Latour 17:45-18:15 Debate 19:30-23:00 Social Event 11 November - SAAWP Educational 9 th session Chair: Marc Bierings 08:00-08:30 MUD transplant for AA. Where we come from, where we are, where we go Jakob Passweg 08:30-08:45 Questions Controversy III: Do I offer upfront MUD in children with aplastic anemia? Chair: Judith Marsh 08:45-09:00 Yes Carlo Dufour 09:00-09:15 No Philip Scheinberg 09:15-09:45 Debate 09:45-10:15 Coffee break

10 th session Chair: Mahmoud Aljurf 10:15-10:45 Refractory AA patients: place and management of Eltrombopag Antonio Risitano 10:45-11:00 Questions Controversy IV: What is the best salvage transplantation approach for refractory AA? Chair: Andre Tichelli 11:00-11:15 CBT Regis Peffault de Latour 11:15-11:30 Haplo Jakob Passweg 11:30-12:00 Debate 12:00-13:00 Lunch 11 th session Chair: Andre Tichelli 13:00-13:30 Telomere disease Rodrigo Calado 13:30-13:45 Questions Controversy V: Transplant for telomeropathy? Chair: Alicia Rovo 13:45-14:00 Yes Jean Hugues Dalle 14:00-14:15 No Danielle Townsley 14:15-14:45 Debate 14:45-15:15 Coffee break

12 th session Chair: Francesca Fioredda & Jean Soulier 15:15-15:45 Clonal evolution in FA patients: all go to transplantation? Jean Soulier 15:45-16:00 Questions 16:00-16:30 Severe congenital neutropenia: anything new? Francesca Fioredda 16:30-16:45 Questions 16:45-17:15 Closing Remarks