Two Week Course Curriculum Catalog

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Welcome to The University of Texas MD Anderson Cancer Center Proton Therapy Center Houston, TX 1840 Old Spanish Trail Houston, TX 77054 Two Week Course Curriculum Catalog 1

Welcome to MD Anderson Cancer Center and the Proton Therapy Center in Houston, TX. We are excited that you have chosen our world-class facilities to further your knowledge and understanding of proton therapy. With the most innovative technology and a multidisciplinary team approach, our cancer experts include radiation oncologist, physicists, medical dosimetrists, nurses, anesthesiologist, radiation therapist and others. Depending on the training track(s) you have chosen, over the course of the next week(s), our goal is to educate you on Clinical Operations, Treatment Planning and/or Physics and Service Maintenance. Any one or all three of these tracks will better prepare you as you engage in new frontiers with proton therapy and extend its benefits to patients with a wide range of cancers. Thank you and enjoy the program! Steven J. Frank, MD Medical Director, Proton Therapy Center Brandon Gunn, MD Associate Medical Director, Proton Therapy Center Matthew Palmer, MBA, CMD Chief Operating Officer, PTC-H X. Ronald Zhu, PhD Physics Director, Proton Therapy Center Mayankkumar Amin, CMD Medical Dosimetry, Clinical Supervisor Charles Merrifield, BS, RT Radiation Therapy, Clinical Supervisor Jo McDonald, RN Nurse Manager Beth De Gracia, RN Research Nurse Supervisor Kristin Jones, MBA Program Coordinator Lee Chamblee, MBA Education Program Coordinator 2

2 Week Training Course September 11 23, 2017 Week 1 (Clinical & Operations) Monday Introduction to Proton Therapy - Clinical 2 hours Monday Introduction to Proton Therapy - Physics 1.5 hours Monday Operations & Facilities 3 hours Monday Service Maintenance 1 hour Tuesday Nursing Overview/Clinical Nutrition 2 hours Tuesday MDs (disease site specific) 6 hours Wednesday MDs (disease site)/mlps/pedi Anesthesia 7 hours Thursday MDs (disease site specific)/pediatrics 5 hours Friday Research (Nurses) 2.5 hours Friday International Patient Center 1 hour Friday Financial Clearance (Optional) 2 hours Week 2 (Treatment Planning and Physics + Service Maintenance) Monday Dosimetrist (6 hrs.) / Physicists (2 hrs.) 6.5 hours Tuesday Dosimetrist (6 hrs.) / Physicists (2 hrs.) 8 hours Wednesday Dosimetrist (6 hrs.) / Physicists (2 hrs.) 7 hours Thursday Dosimetrist (6 hrs.) / Physicists (2 hrs.) 5 hours Friday Dosimetrist (6 hrs.) / Physicists (2 hrs.) 7.5 hours Saturday Physicist 7 hours 3

Educational Objectives After attending the conference, participants should be able to Incorporate the knowledge and skills learned through hands-on practice sessions to better prepare for proton therapy treatments, thus improving patient outcomes (knowledge, competence, performance, patient outcomes), Interpret the effectiveness of proton therapy to assess which intervention would be most appropriate for patients with different solid tumor cancer diagnoses (knowledge, competence), Assess how an interprofessional system will improve the quality of care for patients receiving proton therapy (knowledge, competence), Utilize proton therapy clinical trials and assess their outcomes for a better understanding of the importance and significance in the treatment of cancer (knowledge, competence, performance), Gain a greater appreciation and perspective of the steps and personnel needed to perform quality proton therapy (knowledge, competence). Target Audience This activity is intended for physicians and fellows in medical oncology, surgical oncology, radiation oncology, pediatrics and radiology, clinical research nurses in oncology and trainees. Evaluation A course evaluation form will provide participants with the opportunity to comment on the value of the program content to their practice decisions, performance improvement activities, or possible impact on patient health status. Participants will also have the opportunity to comment on any perceived commercial bias in the presentations as well as to identify future educational topics. Accreditation/Credit Designation The University of Texas MD Anderson Cancer Center is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The University of Texas MD Anderson Cancer Center designates this live activity for a maximum of 57.25 AMA PRA Category 1 Credits TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. CME Certificates and Attendance Verification Certificates Certificates awarding AMA PRA Category 1 Credit TM or certificates documenting attendance will be distributed to participants when an individual departs the conference. To obtain a CME certificate, physicians must submit a completed evaluation questionnaire and a CME Verification Form. Upon request, a record of attendance (certificate) will be provided on-site to other health care professionals for requesting credits in accordance with state nursing boards, specialty societies, or other professional associations. The University of Texas MD Anderson Cancer Center has implemented a process whereby everyone who is in a position to control the content of an educational activity must disclose all relevant financial relationships with any commercial interest that could potentially affect the information presented. MD Anderson also requires that all faculty disclose any unlabeled use or investigational use (not yet approved for any purpose) of pharmaceutical and medical device products. Specific disclosure will be made to the participants prior to the educational activity. Agendas are subject to change because we are always striving to improve the quality of your educational experience. MD Anderson may substitute faculty with comparable expertise on rare occasions necessitated by illness, scheduling conflicts, and so forth. Photographing, audio taping, and videotaping are prohibited. 4

Week 1 (Clinical & Operations) Course down Monday, September 11 Operations & Facilities and MDs (disease site specific) 9:00am 9:30am 9:30am 10:20am Registration + fast Welcome Video + Tour 10:20am 11:00am Introduction to Proton Therapy Clinical 11:00am 11:15am 11:15am 12:30pm Introduction to Proton Therapy Physics 12:30pm 1:30pm 1:30pm 3:30pm 3:30pm 3:45pm 3:45pm 4:45pm with Dr. Cox (Operations/Facilities) Overview of Proton Therapy Center (Patient flow, staffing, special consideration) Service Maintenance 4:45pm 6:00pm Social Event Meet & Greet with Presenters Tuesday, September 12 MDs (disease site specific); Nursing and Clinical Nutrition 9:00am 10:00am MD) Head & Neck (H&N) Evidence/Literature 10:00am 11:15am (MD) H&N Way of Treatment 11:00am 11:15am 11:15am 12:00pm (MD) Head & Neck (H&N) Case Presentation 12:00pm 1:00pm 1:00pm 1:30pm 1:30pm 2:00pm Nursing Presentation Child Life Advocacy 5

2:00pm 2:30pm 2:30pm 2:45pm 2:45pm 3:15pm 3:15pm 4:30pm Clinical Nutrition Radiation Therapy (MD) Lung MDACC way of treatment + presentation Wed., September 13 MDs (disease site specific); MLPs and Pediatric Anesthesia 8:30am 9:15am 9:15am 10:00am 10:00am 10:15am 10:15am 11:00am 11:00am 12:00pm 12:00pm 1:00pm 1:00pm 2:00pm 2:00pm 2:30pm 2:30pm 2:45pm 2:45pm 3:15pm 3:15pm 3:45pm (MD) Lung Evidence/Literature (MD) Lung Quality Safety MLPs (Side effects, exams, problems, writing Rx s) Pediatric Anesthesia (MD) (CNS) Evidence/Literature (MD) Central Nervous System - Quality & Safety (MD) (CNS) MDACC way of treatment (MD) (CNS) Case Presentation Thursday, September 14 MDs (disease site specific) 8:00am 9:00am 9:00am 9:45am 9:45am 10:00am (MD) Genitourinary - Prostate (GU) Evidence/Literature (MD) Genitourinary - Prostate (GU) Case Presentation 6

10:00am 11:00am Observation of Treatment (Gantry) 11:00am 12:00pm (MD) Pediatric Evidence/Literature 12:00pm 1:00pm 1:00pm 1:30pm 1:30pm 2:30pm 2:30pm 2:45pm 2:45pm 3:15pm (MD) Pediatric Quality & Safety (MD) Pediatric MDACC Way of Treatment (MD) Pediatric Case Presentation Friday, September 15 Research Nurses, International Center, and Financial Clearance 9:00am 9:45am 9:45am 10:15am Fundamentals of Clinical Research (Research) Overview of exciting clinical trials and prospective/qol studies at the PTC 10:15am 10:35am (Research) Overview of clinical research at the RCCs and collaborative studies where MDACC is the lead site/collaborating site 10:35am 10:45am 10:45am 11:00am (Research) Overview of interesting studies for our pediatric patients 11:00am 11:10am (Research) Overview of future projects 11:10am 12:10pm 12:10pm 12:40pm 12:40pm 1:10pm 1:10pm 1:20pm 1:20pm 1:50pm 1:50pm 2:20pm International Patient Center Language Assistance Insurance Welcome + Video New Patient Referral Insurance Authorization Process 7

2:20pm 2:35pm 2:35pm 2:50pm 2:50pm 3:00pm Denials & Appeals Final Insurance Approval Process Week 2 (Treatment Planning & Physics) Course down Monday, September 18 Dosimetry/Physics 9:00am 9:30am 9:30am 10:45am Registration/fast + Welcome Address/Video Overview of Proton Therapy Physics 10:45am 11:00am 11:00am 12:45pm Overview of PT Treatment planning 12:45pm 1:30pm 1:30pm 1:50pm 1:50pm 3:50pm 3:50pm 4:00 pm 4:00pm 4:45pm Tour of PTC Dosimetry Treatment Planning & Demo for Prostate (PSPT and SFO) Physics Intro. Motion Management (Adaptive for lung) Tuesday, September 19 Dosimetry/Physics 8:00am 9:45am 9:45am 10:00am Dosimetry Treatment Planning & Demo for Lung (PSPT and SFO) 10:00am 12:00pm Dosimetry Treatment Planning & Demo for Esophagus (PSPT and SFO) 8

12:00pm 1:00pm 1:00pm 2:30pm 2:30pm 2:40pm Dosimetry Treatment Planning & Demo for Head & Neck (SFO & MFO) 2:40pm 4:00pm Dosimetry Treatment Planning & Demo for Head & Neck (SFO & MFO) 4:00pm 5:00pm Physics Introduction to robust optimization Wednesday, September 20 Dosimetry 8:00am 10:15am Dosimetry Treat. Plan. & Demo for CSI 10:15am 10:30am 10:30am 12:00pm Dosimetry Treat. Plan. & Demo for CNS 12:00pm 1:00pm 1:00pm 2:45pm 2:45pm 3:00pm 3:00pm 4:15pm Dosimetry Treat. Plan & Demo GI (Liver) Dosimetry Treat. Plan & Demo APBI (Partial Breast) Thursday, September 21 Physics 9:00am 11:00am Physics Commissioning Passive Scattering (including CT calibration for proton therapy) 11:00am 11:15am 9

11:15am 12:20pm Physics Commissioning Spot Scanning 12:20pm 1:20pm 1:20pm 1:50pm 1:50pm 3:00pm Treat. Plan. Sys. Commissioning Passive Treat. Plan. Syst. commissioning Scanning Friday, September 22 Physics 8:00am 8:50am 8:50am 9:45am 9:45am 10:00am Proton Dose Calculation Algorithms Advanced Optimization for Scanning Beam (robust optimization and robust analysis) 10:00am 10:45am Advanced motion management 10:45am 11:45am Machine QA for passive scattering 11:45am 12:45pm 12:45pm 1:45pm 1:45pm 2:30pm 2:30pm 2:45pm 2:45pm 3:30pm Machine QA for scanning Patient specific QA for passive scattering Patient specific QA for scanning Saturday, September 23 Physics 8:00am 4:00pm Observation 10

PTC Training Registration Fees One Two Weeks Program 1 Clinical & Operations (5 days) (Week 1) (5 days Mon Fri) = $3,200 registration fee Program 2 Treatment Planning (Dosimetrist) (3 days) (Week 2) (3 days Mon Wed) = $2,600 registration fee Program 3 Physics (Physicist) (3 days) (Week 2) (3 days Thurs Sat) = $2,600 registration fee Program 4 Treatment Planning + Physics (6 days) (Week 2) (6 days Mon Sat) = $5,000 registration fee Program 5 Clinical & Operations + Treatment Planning + Physics (11 days) (Weeks 1 & 2) (11 days Mon Sat) = $8,000 registration fee 11