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OncoRay National Center for Radiation Research in Oncology, Dresden WELCOME Wifi: Network: UKD_Dozent Username: ukd-guest536 Password: mvhffjs3 is also available

OncoRay National Center for Radiation Research in Oncology, Dresden Welcome note 7th International workshop for planning and delivery of radiotherapy to non-static targets Antje Knopf, Christoph Bert, Kristin Stützer, Christian Richter

Outline Where we are brief info about OncoRay Who we are participants What we will be doing organizational infos Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 3

Some facts about OncoRay Funded in 2004 with federal funding Joint center operated and supported by: Technical University Dresden Helmholtz-Center Dresden-Rossendorf University Hospital Carl Gustav Carus 2010 Nominated National center for Radiation research in Oncology (together with HIRO/DKFZ in Heidelberg) Focus: Preclinical and clinical translational research in radiation oncology Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015

OncoRay research groups Improved treatment of cancer by means of biologically individualized, technically optimized radiotherapy. Translational research In vivo Dosimetry Molecular and celluar radiobiology Biomarker Laser-Radiooncology Medical radiation Physics Preclinical Imaging Tumorpathophysiology MRI based radiotherapy Image guided high precision radiotherapy High precision radiotherapy Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015

The Dresden proton facility Full integration in existing clinical infrastructure One clinical treatment room Research infrastructure in the same building (animal lab, small animal imaging+irradiation, physics and radiobiological research) 01.04.2010 Start of tendering procedure xx.01.2011 Contract signed with IBA xx.07.2012 Start of building construction 16.07.2013 First beam in treatment room 10.06.2014 Start clinical commissioning 12.12.2014 First clinical treatment Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 6

The Dresden proton facility 16 Energy selection system: 70 230 MeV Gantry: Ø = 11 m m = 120 t Treatment room: 100 m 2 Experimental area: 250 m 2 Isochron-Cyclotron, 230 MeV Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 7

The Dresden proton facility Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 8

Who we are some statistics about participants and abstracts Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 9

Registrations 71 participants 7 64 Academic institutions Industry 64 participants from academic institutions: From 31 research institutes From 11 countries Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 10

Countries of origin (academic participants) Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 11

Countries of origin (academic participants) Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 12

Industry representatives 7 representatives (from 12 companies invited) Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 13

Academic participants: Particle vs. Non-Particle Participants from particle centers 45% 23% 11% Protons Carbon 20% In preperation No particle center Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 14

Abstracts Particle vs. Non-Particle 23% Protons 65% 13% Carbon Not particle related Topics 23% 6% 32% 4D DOSE CALCULATIONS AND DOSIMETRIC ANALYSES CLINICAL APPLICATIONS 4D IMAGING 16% 10% 13% MEASUREMENTS AND PHANTOM STUDIES MOTION ACQUISITION BY ULTRASOUND AND MOTION MODELLING DATABASES Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 15

What we will be doing the next two days some organizational infos Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 16

Today morning THURSDAY, 26 TH NOVEMBER 2015 9:30 WELCOME NOTE 10:00-11:30 CURRENT CLINICAL PRACTICE - REPORT ON A SURVEY ON 12 PARTICLE THERAPY CENTERS - CLINICAL POINT OF VIEW AND GENERAL OVERVIEW - PRACTICAL EXPERIENCE AND NEEDS FROM A CLINICIANS POINT OF VIEW ANTJE KNOPF (ICR LONDON) MICHAEL BAUMANN (ONCORAY DRESDEN) STEPHANIE COMBS (TU MÜNCHEN) 11:30-13:00 LUNCH Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 17

Lunch Or just follow us! Don t forget your vouchers! Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 18

Today afternoon THURSDAY, 26 TH NOVEMBER 2015 13:00-14:30 4D + ROBUST TREATMENT PLANNING - WHAT HAVE COMMERCIAL SYSTEMS TO OFFER WHAT DO WE NEED? - 4D MONTE CARLO - ROBUST PLANNING AND MARGIN CONCEPTS: WHAT IS THE WAY TO GO? FRANCESCA ALBERTINI (PSI VILLIGEN) MARCUS ALBER (AARHUS UNIVERSITY) MISCHA HOOGEMAN (ERASMUS MC ROTTERDAM) 14:30-17:00 COFFEE BREAK + POSTERS 17:00-17:30 MOTION MONITORING IGRT ART (I) - WHAT CAN WE LEARN FROM IGRT OF PHOTONS? ANNE RICHTER (UNIVERSITY HOSPITAL WÜRZBURG) 17:45-18:30 SITE TOUR 19:30 CONFERENCE DINNER Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 19

Workshop Dinner Italienisches Dörfchen Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 20

19:30 Workshop Dinner Direct route from OncoRay: Tram #12 to Leutewitz, exit Postplatz If you want: Let s meet 6:50 pm in the Lobby Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 21

Tomorrow FRIDAY, 27 TH NOVEMBER 2015 08:30-09:30 MOTION MONITORING IGRT ART (II) - Integration of new imaging capabilities in proton therapy - What is new in motion monitoring and motion modelling TONI LOMAX (PSI VILLIGEN) GUIDO BARONI (POLITECNICO DI MILANO) 09:30-10:00 COFFEE BREAK 10:00-11:30 MOTION MODELLING AND DEFORMABLE REGISTRATION - New developments and improvements in DIR - Relating motion to external surrogates - How to verify DIR? Can we use DIR in the clinic and for which purpose? HUGO FURTADO (MEDICAL UNIVERSITY OF VIENNA) DANIEL LOW (UCLA) DAVE HAWKES (UNIVERSITY COLLEGE LONDON) 11:30-13:00 LUNCH 13:00-14:30 4D DOSIMETRY - Overview in vivo verification including 4D capabilities WOLFGANG ENGHARDT (ONCORAY DRESDEN) - 4D simulation of secondary emissions for in vivo verification - Prompt-Gamma techniques and its 4D capabilities KATIA PARODI (LMU MUNICH) GUNTRAM PAUSCH (ONCORAY DRESDEN) 14:30-14:45 COFFEE BREAK 14:45-15:45 PANEL DISCUSSION SUMMARY 15:45-16:00 Christian Richter 4D Treatment Planning Workshop, Dresden, Report, November Poster award, 26-27, Location 2015 & focus next year 22

It is about your comments & questions Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 23

Enjoy the workshop, enjoy your stay in Dresden Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 24

Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 25

1) Fried potato patty with salad and chive (vegetarian) (upstairs) 2) Baked Coalfish with spinach-cheese-filling, mashed potatos and cucumber salad (upstairs) Gourmed) Thai-like beef stripes with rise and chinese cabbage (downstairs) Christian Richter 4D Treatment Planning Workshop, Dresden, November 26-27, 2015 26