OR + SMA T THERMOGRAPH. Cold? Sinusitis? Arthritis? Other inflammation? What is your choice on a shelf in mall or pharmacy?

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SMA T THERMOGRAPH OR + Cold? Sinusitis? Arthritis? Other inflammation? What is your choice on a shelf in mall or pharmacy?

The main market 70000000 65000000 Adults with doctor diagnosed arthritis in U.S. Inflammation visualization Arthritis is the most common cause of disability adults for the past 15 years globally and costs $128 bln a year. 60000000 55000000 50000000 45000000 2000 2005 2010 2015 2020 2025 2030 2035 Adults (18-65) arthritis distribution 12.9% 9.8% 67.5% Low risk Have diagnosed arthritis Have life&work limitations There is no efficient home device solution for arthritis monitoring on the market http://www.cdc.gov/arthritis/data_statistics/arthritis_related_stats.htm

Smart Thermograph Inflammation visualization Market gap - opportunity Medical self-care devices & mhealth market Diabetes Arthritis Hypertonia

The product sample package Inflammation visualization Local temperature increase is a well-known sign of arthritis, sinusitis and other inflammatory sicknesses of organs close to the skin surface. (Clinical study can be found here in Appendix 1 )

The product Smart Thermograph device with Bluetooth LE Source of raw data Free application for iphone, Android or Windows User interface Data interpretation Web service Data storage Integration with other services Data analysis & sharing Retail price ~$59

The product Patented medical intelligent inflammation monitoring device for home use Provide treatment monitoring of inflammation accompanying arthritis and 100+ inflammatory diseases of organs close to skin surface Treatment efficiency thermo monitoring of inflammation Lifestyle correction to prolong time to disability Build precise and medically correct thermograms Measure surface temperature at any area of a body Adds value to the standard medical body thermometer by novel but easy to understand and highly demanded functions IR thermometers with Surface temperature function are FDA/CE approved Existing on the market business model is used

Target audience The product is intended for more than 50% of global population: People who suffer from one or several of 100+ chronic inflammation diseases (Arthritis, Phlebitis, Pulpitis, Lymphadenitis, Dermatitis, Sinusitis, Laryngitis, Tracheitis, Mastitis, Myositis, Prostatitis, Post Injection Inflammation, etc.). People after trauma Helps to solve quality of life problem for people with arthritis by: Promotion of treatment efficiency Finding correct zone to rub gels and apply other local treatment Lifestyle correction

Chronical inflammation sicknesses Minimal sales Best point for sales Minimal sales 35 First chronical inflammation sickness diagnosed by a doctor 45 Development of the first and appearance of others sicknesses Lifestyle is getting worse Active search of solutions 70 Sicknesses are developed Less active search for solutions

Conservative market volume estimation Device Target global population (%) Device sales volume (est.) Glucometer 10% 60 mln per year Tonometer 35% 15 mln per year Smart Thermograph 20% 60 mln per year Smart Thermograph 31% Others 4% Total market (per year) $6 bln 20% $1.5 bln 1.5% $3.6 bln 10% Conversion (without device replacement) Estimation Tonometer 13% Glukometer 52% Source: IHS

Market goals MARKET SHARES Others Conventional thermometers Tonometers Smart Thermograph - new niche MARKET SHARES (GOAL) Conventional thermometers Tonometers Glukometers Others Glukometers Goal: Create a new niche of home inflammation monitoring devices with full patent monopoly in it Method: Using existing distribution & production chains introduce the standard thermometer with unique thermograph features

Business model Contractor Product liability Regional certification organization Online Smart Thermograph LTD Regional distributor Mall Distribution agreement Pharmacy Third-party apps Inflammation visualization Smart Thermograph LTD Owns and manages intellectual property (patents, trade marks) Manages production, manages development of hardware and software Certification support for distributors Regional distributor Manages certification, sales and support in the region Distributor may not have any marketing budget as it uses standard available sales channels

Success history Personal blood pressure monitoring market Hypertension is estimated to affect 43 to 56 million adults or 24% to 31% of the US population and is emerging as a major health problem in some countries in the Third World. 1-3 Hypertension contributes to all the major atherosclerotic cardiovascular disease outcomes. Consumers generally prefer machines with digital readouts and are purchasing an increasing number of electronic HBP monitors (Eric Vennemeyer, written communication, December 10, 1997). 24 Sales of electronic monitors have increased from 57% of the world market in 1992 to 58% in 1995 and are expected to increase to 68% in 2002. http://archinte.jamanetwork.com/article.aspx?articleid=485316

WE INVITE DISTRIBUTORS RECOMMENDED RETAIL PRICE $59

Appendix 1 MARKETING DETAILS

Market volumes Smart Thermograph solution for monitoring Chronic inflammatory diseases organs close to skin surface (arthritis, sinusitis, phlebitis, myositis etc.) Independent aging (arthritis major reason for restricting ability to move)

Applicable sicknesses The Smart Thermograph is intended for thermo monitoring of inflammation skin and organs located near skin: Dermatitis, eczema, abscess, furuncle, carbuncle, cellulitis, arthritis and polyarthritis, periarthritis, tendinitis, bursitis, epicondylitis, fasciitis, pulpitis, osteitis, synovitis, tenosynovitis, periostitis, sialoadenitis, lymphadenitis, thyroiditis, otitis, mastoiditis, sinusitis, laryngitis, tracheitis, tonsillitis, mastitis, phlebitis, thrombophlebitis, angiitis, lymphangitis, polymyositis, myositis, prostatitis, injury etc. Smart Thermograph is not intended for diagnostics of any diseases and not intended for thermo monitoring of inflammation diseases of organs located deeply in regard to skin surface (e.g. nephritis, pyelonephritis, gastritis, colitis, pancreatitis, cholecystitis, encephalitis etc.). You may find complete clinical research in top world medical magazines here http://smart-thermograph.com/wp-content/uploads/2014/12/medical_review.doc

Smart Thermograph is the cheapest and efficient technology ever Inflammation visualization Thermograph IR CCD\CMOS matrix Provides instant thermogramm Impossible to compare results for monitoring Not applicable for curved body areas* Applicable in professional setup Smart Thermograph Single sensor Takes 1 sec to measure 1 point* Automatically compare results for monitoring Applicable for all body areas Applicable at home * For the details please refer to the movie for experts on the site http://

Thermometer Thermometer is the simplest tool for inflammation thermo monitoring. Thermometer measures the overall body temperature to assess the common inflammation of the body. However, it is insufficient for revealing of local thermo signs of inflammation diseases, visualization, estimation of the effectiveness of therapy, thermo monitoring of diseases. Smart Thermograph provides visualization of inflamed area and intelligent treatment thermo monitoring.

Comparison with similar products The most popular home medical device Automatic tonometer Electronic glucometer Conventional thermometer Smart Thermograph Diseases for monitoring Hypertension Hypotension Visualization of the health problem Measureme nt accuracy Automatic interpretati on Educational market barriers Patent protection No Satisfactory No Medium No Diabetes No Satisfactory No Medium No Inflammatory diseases/nonspecifically Inflammatory diseases/local thermosigns (100+ diseases) No Satisfactory No Low No Yes Satisfactory Yes Medium Yes (up to 2029)

Application comparison for inflammation sicknesses Smart Thermograph is efficient for all ages Child Adult Senior Body temperature reactivity Local temperature reactivity Standard (body) thermometer efficiency Smart Thermograph efficiency High Moderate Low High High High High Moderate Low High High High

Usage scenario Inflammation visualization Inflammation sickness diagnosed Diagnose is conducted only by a doctor. This requirement is stated in the product manual Smart Thermograph boundaries First thermo monitoring session Objective thermo signs of inflammation Dimensions of inflamed area Precise location for local therapy Gel applied or medicine taken Negative or Positive dynamics All subsequent thermo monitoring sessions Negative or Positive dynamics Some other treatment activities conducted Visual and digital dynamics of inflammation thermosigns Objective treatment efficiency monitoring

Smart Thermograph advantages in accuracy Single value Incorrect position Shaking hands Multiple spatial measurements Tolerant to positioning errors Averages measurements Low precision Higher accuracy

Technical details Smart Thermograph method is a visualization method of temperature fields of a biological object skin surface providing medically correct distribution of the temperature. Special grid of points allows unrevealing of temperature gradient between the measurement points and identify areas of relative normo-, hypo-, hyper- thermia of measured area. For inflammation sicknesses areas of hyperthermia are relevant. Color visualization provides a handy way to analyze inflammation process. During inflammation of skin surface and organs placed close to skin surface temperature of inflamed area is increased\decreased depending on the dynamics of inflammation process. Those trends are automatically being interpreted by software service.

Umbrella EU patent claim 1. A method of displaying a temperature field of a biological object, the method comprising the steps of: obtaining temperature measurements of an area of a biological object; obtaining an image of the area of the biological object; generating an image of a temperature field of the area of the biological object and superimposing the image of the temperature field on the image of the area of the biological object; displaying the superimposed image of the temperature field on the image of the area of the biological object on a computer screen, wherein an area of the biological object is an area of human skin surface; an image of the area of the biological object is a photographic image of the area of the human skin surface; characterized in that: before the temperature measurements are obtained: obtaining and displaying on the computer screen a photographic image of the area of the human skin surface; marking points by graphic indications on the photographic image displayed on the computer screen, the points marked by graphic indications on the photographic image correspond to the points on the area of the human skin surface on which measurements of temperature will take place; displaying on the computer screen a photographic image with marked graphic indications of points marked on it; herewith obtaining temperature measurements by infrared thermometer or infrared pyrometer consistently at the points of the area of the human skin surface in correspondence with the points marked by graphic indications on the photographic image, wherein temperature measurements are obtained by an infrared thermometer or an infrared pyrometer. 2. The method of claim 1, wherein the temperature field of the area of the human skin surface is formed by interpolation of temperatures, measured at the measurement points on the area of the human skin surface. 3. The method of claim 2, wherein the temperature field of the area of the human skin surface is formed by linear interpolation of temperatures, measured in adjacent measurement points on the area of the human skin surface. 4. The method of claim 2, wherein the image of the temperature 5 field of the area of the human skin surface is displayed on the computer screen in accordance with a computer program color palette, in which each specific color corresponds to a temperature value. 5. The method of claim 1, wherein the temperature measurements are displayed in a numerical form on the screen of the computer at the corresponding measurement points on the image of the area of the human skin surface. 6. The method according to any previous claim, wherein the temperature measurements are obtained serially. 7. The method according to any previous claim further comprising the step of saving the temperature field in a database. 8. The method according to any previous claim, wherein each point where a temperature measurement is to be taken is displayed on the image sequentially following a temperature measurement of a previous point. 9. A computer program comprising program instructions that, when executed on a computer cause the computer to perform the method of any of claims 1 to 8.