Integrated Management of Acute and Chronic. Coronary Artery Disease. FINAL PROGRAM From Prevention to Intervention

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19 th International Meeting Integrated Management of Acute and Chronic Coronary Artery Disease From Prevention to Intervention ORGANIZERS: KURT HUBER (Austria) HARALD DARIUS (Germany) BERNARD GERSH (USA) CHRIS GRANGER (USA) OTMAR PACHINGER (Austria) MAIN TOPICS: Acute Coronary Syndromes Antiplatelet Agents Anticoagulants Atrial Fibrillation Biomarkers Cardio-Oncology Case Presentations Coronary Artery Disease Devices, New Interventional Cardiology Lipid Lowering Strategies Master Lectures Miscellaneous Structural Heart Disease Translational Medicine (Abstracts) Innsbruck, Austria Austria Trend Congress Hotel January 27-30, 2018 FINAL PROGRAM www.cardio-congress.com

PREFACE This international meeting celebrates its 19 th Anniversary. As in the past, the meeting is organized by the Association for the Promotion of Research in Arteriosclerosis, Thrombosis and Vascular Biology (ATVB), Vienna, Austria. It is patronized by the European Platelet Academy (EPA, and by the Working Group on Thrombosis and the Acute Cardiovascular Care Association (ACCA), both registered branches of the ESC, respectively. In 2018, more than 40 international and national experts will guarantee an interesting conference with important topics illustrating the most contemporary and topical clinical research data mainly in the field of acute coronary syndromes, acute cardiac care, atrial fibrillation, interventional cardiology, heart failure and prevention. A major focus will be on pharmacotherapy and devices as has been the case in prior meetings. Master lectures and interactive clinical case discussions will extend our knowledge and enhance the practical relevance of the program. The number of attendees is limited to a maximum of 100 persons in order to stimulate intense discussions with international experts on case presentations and main topics a rare situation in our world of mega-congresses. The organizers will also invite the presenters of the best abstracts (a maximum of 24 abstracts will be accepted) to discuss their data with faculty members in moderated poster presentations. The best-of- translational medicine and best-of-clinical medicine posters will be awarded. This service will mainly refer to the group of young cardiologists of tomorrow. In addition, presenters of posters will have free access to the whole meeting. We would welcome your participation at this meeting. With best regards Kurt Huber (for the organizers) Patronage Sigmund Freud Privatuniversität Wien Österreichischer Herzfonds DEADLINE FOR ABSTRACT SUBMISSION January 10, 2018 (send your abstracts, A4 format, directly to kurt.huber@meduniwien.ac.at) 1

FINAL PROGRAM Saturday, January 27, 2018 Arrivals 19:30 Welcome Cocktail and Get-Together Evening Sunday, January 28, 2018 09:00-11:00 Symposium 1: Diagnostics and Antithrombotic Challenges in ACS (partially supported by Thermo Fisher) chairs: D. Gulba (DE), P. Clemmensen (DK) 09:00-09:15 Case Presentation #1 (H. Alber, AT) 09:15-09:40 Fast Rule-in and Rule-out of Myocardial Infarction (M. Möckel, DE) 09:40-10:05 Prasugrel vs. Ticagrelor in STEMI What Is Known (Stefanie Schüpke, DE) 10:05-10:20 Case Presentation #2 (Suzanne De Waha, DE) 10:20-10:40 Unresolved Issues with Antithrombotic Therapies in ACS (H. Darius, DE) 10:40-11:00 Cangrelor Soon in Clinical Routine? (S. Kristensen, DK) 11:00-11:30 Break, Exhibition 11:30-12:30 Symposium 2: Devices and Strategies Revisited chairs: H. Thiele (DE), R. Welsh (CA) 11:30-11:50 IMPELLA Expections, Indications, Experience (D. Westermann, DE) 11:50-12:10 FFR, IFR, CT-FFR Which Is to Prefer? (Irene Lang, AT) 12:10-12:30 Chronic Total Occlusions Where Do We Stand (P. Clemmensen, DK) 12:30-13:30 Lunch Break, Exhibition, Moderated Posters A (moderators: J. Wojta, AT, D. Gulba, DE) 2

FINAL PROGRAM Sunday, January 28, 2018 13:30-14:30 Symposium 3: Bioabsorbable Scaffolds and Other News chairs: A. Kastrati (DE), S. Kristensen (DK) 13:30-13:55 Preclinical Data and Thrombogenicity (M. Joner, DE) 13:55-14:15 Update on the Clinical Trials Program with the Mg Scaffold (H. Schühlen, DE) 14:15-14:30 Case Presentation #3 (J. Falkensammer, AT) 14:30-15:30 Symposium 4: Lost Paradises chairs: O. Pachinger (AT), R. De Caterina (IT) 14:30-14:45 ABSORB Data Revisited (A. Kastrati, DE) 14:45-15:00 Case Presentations #4 & #5 (M. Rohla, AT) 15:00-15:15 Seralaxin in Acute Heart Failure (M. Böhm, DE) 15:15-15:30 Vorapaxar in CAD (U. Zeymer, DE) 15:30-16:00 Break, Exhibition 3

FINAL PROGRAM Sunday, January 28, 2018 16:00-17:40 Symposium 5: Atrial Fibrillation chairs: J. Camm (UK), S. Kristensen (DK) 16:00-16:25 Subclinical AFib: Screening, Detection, Treatment (B. Gersh, US) 16:25-16:45 Is it Time to Abandon Digoxin in AF? (M. Borggrefe, DE) 16:45-17:00 Case Presentation #6 (Anna Rab, AT) 17:00-17:20 Evaluating How to Improve Anticoagulation for AFib (C. Granger, US) 17:20-17:40 NOAC Reversal Agents (R. De Caterina, IT) 17:40-18:05 Allan Ross Memorial Lecture Are Solid Tumors Associated with P2Y12-Inhibitor Therapy? (A. Lyon, UK) 4

FINAL PROGRAM Monday, January 29, 2018 09:00-11:00 Symposium 6: Valvular Heart Disease chairs: D. Westermann (DE), U. Zeymer (DE) 09:00-09:25 Pathophysiology and Management of Functional Mitral Regurgitation (B. Gersh, US) 09:25-09:40 Case Presentation #7 (C. Kaulfersch, AT) 09:40-10:05 TAVR Update 2018 (R. Welsh, CA) 10.05-10:20 Case Presentation #8 (S. Heindl, AT) 10:20-10:45 Tricuspidal and Pulmonal Valve Interventions Update 2018 (H. Thiele, DE) 10:45-11:00 Case Presenttion #9 (Suzanne De Waha, DE) 11:00-11:30 Break, Exhibition 11:30-12:30 Symposium 7: Device Therapy Update 2018 (supported by Boston Scientific) Moderation: K. Huber (AT) 11:30-11:55 Left Atrial Appendix Occlusion or Anticoagulation in Atrial Fibrillation (R. K. Binder, AT) 11:55-12:20 DES and DAPT Update 2018 (R.A. Byrne, DE) 12:20-12:30 General Discussion 12:30-13:30 Lunch Break, Exhibition, Moderated Posters B (moderators: J. Wojta, AT, P. Clemmensen, DK) 5

FINAL PROGRAM Monday, January 29, 2018 13:30-14:30 Symposium 8: Innovations in Cardiovascular- Metabolic DIsease Treatment: Advance in Patient Care (supported by Boehringer Ingelheim) Moderator: K. Huber (AT) 13:30-14:00 Optimizing Stroke Prevention in Patients with Atrial Fibrillation and Acute Coronary Syndromes (M. Stühlinger, AT) 14:00-14:30 From Evidence to Clinical Practice Case Presentation #10 (K. Huber, AT) 14:30-15:30 Symposium 9: Acute Cardiovascular Care Joint Symposium with ACCA chairs: U. Zeymer (DE), V. Gasparovic (HR) 14:30-14:50 Contrast Medium Induced Renal Failure (V. Gasparovic, HR) 14:50-15:10 Case Presentations #11 & #12 (H. Thiele, DE) 15:10-15:30 The Echocardiogram in Acute CV Care (Susanna Price, UK) 15:30-16:00 Break, Exhibition 16:00-18:30 Symposium 10: Master Lectures I chairs: Susanna Price (UK), H. Schühlen (DE) 16:00-16:25 What Are the Needs and Challenges for an Editor (J. Camm, UK) 16:25-16:50 Chronic Heart Failure What is New (M. Böhm, DE) 16:50-17:15 Women in Heart Disease (Roxana Mehran, US) 17:15-17:40 Vasovagal Syncope (B Gersh, US) 17:40-18:05 Lessons from a Trialist (S. Pocock, UK) 18:05-18:30 Pragmatic Trials: How, for What? (C. Granger, US) 6

FINAL PROGRAM Tuesday, January 30, 2018 09:00-11:05 Symposium 11: Master Lectures II chairs: V. Gasparovic (HR), H. Darius (DE) 09:00-09:25 Cardiovascular Disease and Pregnancy (Irene Lang, AT) 09:25-09:50 Major Clinical Trials in Antithrombotic Therapy Published 2017 (R. Welsh, CA) 09:50-10:15 Stress Cardiomyopathy (A. Lyon, UK) 10:15-10:40 Coronary Artery Dissection (Roxana Mehran, US) 10:40-11:05 What Will Stay from Biomarkers in 10 Years? (C. Müller, CH) 11:05-11:30 Break, Exhibition 11:30-12:30 Symposium 12: New Information About NOACs Moderator: K. Huber (AT), C. Müller (CH) 11:30-11:55 What Real World Data Tell Us (H. Darius, DE) 11:55-12:10 Case Presentation #13 (J. Auer, AT) 12:10-12:30 Anticoagulation for Chronic Vascular Disease: How Should COMPASS Change Patient Care? (C. Granger, US) 12:30-13:30 Lunch Break, Exhibition, Moderated Posters C (moderators: P. Clemmensen, DK, D. Gulba, DE) 7

FINAL PROGRAM Tuesday, January 30, 2018 13:30-14:30 Symposium 13: Optimal Secondary Prevention in High-Risk Patients Moderator: T. Wascher (AT), Suzanne De Waha (DE) 13:30-13:50 PCSK9-Inhibition for LDL-C Reduction (H. Drexel, AT) 13:50-14:10 Case Presentations #14 & #15 (S. Harb, AT) 14:10-14:30 Which Oral Antidiabetic Agent for Which Diabetic Patient (T. Wascher, AT) 14:30-15:30 Symposium 14: Clinical Trials Methods chairs: H. Drexel (AT), O. Pachinger (AT) 14:30-14:55 Non-inferiority: Rationale, Methods, Interpretation (S. Pocock, UK) 14:55-15:20 Endpoints in Clinical Trials: The Dilemma between Hard and Soft Clinical Endpoints and Practicality (B. Gersh, US) 15:20-15:30 General Discussion 15:30-15:50 Impulse Lecture Combined Anticoagulation and Antiplatelet Therapy in Afib with Stenting: Evolving Evidence K. Huber (AT) 15:50-16:00 Poster Awards & Farewell K. Huber (AT) 16:00 End of Meeting 8

GENERAL INFORMATION Meeting Organization Association for the Promotion of Research in Arteriosclerosis, Thrombosis and Vascular Biology (ATVB) Mariahilferstrasse 49, A-1060 Vienna, Austria Responsible for the Scientific Program Kurt Huber, MD, FESC, FACC, FAHA Director, 3 rd Department of Medicine Cardiology & Intensive Care Medicine, Wilhelminenhospital Montleartstrasse 37, A-1160 Vienna, Austria Tel.: +43/1 49 150-2301, Fax: +43/1 49 150-2309 E-mail: kurt.huber@meduniwien.ac.at Congress Secretariat Congress and Study Concept GesmbH Widerhoferplatz 4/3/19, A-1090 Vienna, Austria Contact: Ms. Mag. Franziska Beckmann Phone/Fax: +43/699 11516917 E-mail: csconcept@chello.at Medical Exhibition, Sponsoring &Advertising Medizinische Ausstellungs- und Werbegesellschaft Freyung 6, A-1014 Vienna, Austria Contact: Ms. Sonja Chmella Phone.: +43/1 536 63-32, Fax: +43/1 535 60 16 E-mail: sonja.chmella@media.co.at, www.maw.co.at Venue Austria Trend Hotel, Innsbruck Rennweg 12a, A-6020 Innsbruck Phone: +43/512 2115-0, Fax. +43/512 2115-500 E-mail: congress@austria-trend.at Congress Fee: 600. /300. (reduced fee for physicians in education) 2-day attendance: 400. /200. 1-day attendance: 200. /100. Online Registration https://registration.maw.co.at/coronary18 This CPD event has been accredited for the CPD diploma of the Austrian Medical Chamber with 28 credit points (ID 599250). www.cardio-congress.com 9

GENERAL INFORMATION Information for Poster Presenters You will get notion of acceptance of your abstract latest until January 15, 2018. There will be free access to the whole meeting for poster presenters. Posters should be mounted on the indicated day (Sunday, Monday, or Tuesday) from 9:00 AM to 7:00 PM and removed at the evening of the respective day. Poster presentation (3 min) and discussion (3 min) will take part during the indicated poster moderation sessions. Poster size should not exceed 130x90 cm (height x width) The best basic and clinical research posters will awarded on Tuesday, January 30, 2018 at the end of the meeting. www.cardio-congress.com 10

SPONSORS (as per printing date)

INVITED FACULTY Chairs and Speakers Hannes ALBER (Austria) Ronald K. BINDER (Austria) Michael BÖHM (Germany) Martin BORGGREFE (Germany) Robert A. BYRNE (Germany) John CAMM (United Kingdom) Peter CLEMMENSEN (Denmark) Harald DARIUS (Germany) Raffaele DE CATERINA (Italy) Suzanne DE WAHA (Germany) Heinz DREXEL (Austria) Vladimir GASPAROVIC (Croatia) Bernard GERSH (USA) Christopher GRANGER (USA) Dietrich GULBA (Germany) Kurt HUBER (Austria) Michael JONER (Germany) Adnan KASTRATI (Germany) Steen D. KRISTENSEN (Denmark) Irene LANG (Austria) Alex LYON (United Kingdom) Roxana MEHRAN (USA) Martin MÖCKEL (Germany) Christian MÜLLER (Switzerland) Otmar PACHINGER (Austria) Stuart POCOCK (United Kingdom) Susanna PRICE (United Kingdom) Helmut SCHÜHLEN (Germany) Stefanie SCHÜPKE (Germany) Markus STÜHLINGER (Austria) Holger THIELE (Germany) Thomas WASCHER (Austria) Rob WELSH (Canada) Dirk WESTERMANN (Germany) Johann WOJTA (Austria) Uwe ZEYMER (Germany) Case Presenters Johann AUER (Austria) Jürgen FALKENSAMMER (Austria) Stefan HARB (Austria) Jörg HEINDL (Austria) Carl KAULFERSCH (Austria) Anna RAB (Austria) Miklos ROHLA (Austria) Printed in Austria by: ROBIDRUCK A-1200 Vienna www.robidruck.co.at www.cardio-congress.com