Hashing Out the Issues: Health and Safety in the Marijuana Industry Marijuana and Public Health

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Hashing Out the Issues: Health and Safety in the Marijuana Industry Marijuana and Public Health Mike Van Dyke, Ph.D., CIH Branch Chief Environmental Epidemiology, Occupational Health, and Toxicology

CDPHE and Retail Marijuana (C.R.S. 25-1.5-111 & SB-13-283) Surveillance Role "Monitor changes in drug use patterns, broken down by county and race and ethnicity, and the emerging science and medical information relevant to the health effects associated with marijuana use.

CDPHE and Retail Marijuana (C.R.S. 25-1.5-111 & SB-13-283) Retail Marijuana Public Health Advisory Committee "The Department shall appoint a panel of health care professionals with expertise in cannabinoid physiology to monitor the relevant information. The panel shall: Provide a report by 1/31/15 and every 2 years thereafter* Establish criteria for 1) studies to be reviewed, and 2) reviewing studies and other data, and Make recommendations, as appropriate, for policies intended to protect consumers of marijuana or marijuana products and the general public.

Legal Marijuana and Public Health Monitor health effects Changes in use Accidents Poisonings Chronic health issues Education and Prevention Adolescent use Pregnant or nursing mothers Product safety and storage Occupational health and safety Infused product safety Laboratory practices Waste disposal

CDPHE Internal Governance Retail Marijuana Public Health Advisory Committee (SB-13-283) CDPHE Internal Retail Marijuana Steering Committee Disease Control and Environmental Epidemiology Preventative Services Environmental Health and Sustainability Center for Health and Environmental Data Laboratory Services Hazardous Waste and Waste Management Health Facilities and EMS Health Surveillance, Medical Literature Reviews, Outbreak Investigations, Occupational Health and Safety Prevention and Education Campaign, Clean Indoor Air Act Infused Product/Edible Safety (consultative) Health Behavior Surveys, Data Analysis Laboratory Certification, Contaminant Analysis Consultation Marijuana and Byproduct Disposal Issues (consultative) Trauma Registry, Guidance for Health Facilities

CDPHE Monitoring Activities Target Pop. Problem Monitoring Young Children Accidental Poisoning Pilot surveillance project Colorado Hospital Association (CHA) Data Rocky Mountain Poison and Drug Center Calls Child Health Survey(CHS) - risk factors Youth Increased Use/Abuse Healthy Kids Colorado Survey (aka YRBS) Adults Pregnant/ Breastfeeding Poisoning, Overdose, Abuse Accidents/Trauma Increased Use/Abuse Poisoning, Overdose, Abuse Accidents/Trauma Contaminated Products Birth Defects, Developmental Disabilities Colorado Hospitalization Data Rocky Mountain Poison and Drug Center Calls Colorado Hospitalization Data Colorado Trauma Registry Behavioral Risk Factor Surveillance System (BRFSS) Tobacco Attitudes and Behaviors Survey (TABS) Colorado Hospitalization Data Rocky Mountain Poison and Drug Center Calls Colorado Hospitalization Data & Trauma Registry Pilot Surveillance (Ski-Related Injuries) Foodborne Illness Surveillance related to Edibles Rocky Mountain Poison and Drug Center Calls Pregnancy Risk Assessment Monitoring System (PRAMS) Active Surveillance (Birth Defects Registry)

Retail Marijuana Public Health Advisory Committee Mike Van Dyke, Ph.D. (Chair) Epidemiologist Colo Dept of Pubic Health & Env Ken Gershman, MD, MPH Public Health Physician Colo Dept of Pubic Health & Env Laura Borgelt, PharmD Pharmacologist University of Colorado Hospital Russell Bowler, MD, PhD Pulmonologist National Jewish Health Al Bronstein, MD Poison Control Representative Rocky Mountain Poison and Drug Center Ashley Brooks-Russell, PhD Health Risk Behaviors Colorado School of Public Health Heath Harmon, MH Local Public Health Representative Boulder County Public Health Sharon Langendeorfer, MB Obstetrics Denver Health Bruce Mendelson, MPA Drug Epidemiology Denver Office of Drug Strategy Andrew Monte, MD, MSc Medical Toxicologist University of Colorado Hospital Judy Shlay, MD Public Health Surveillance Denver Health Psychiatrist/Addiction Christian Thurstone, MD Medicine University of Colorado Hospital George Sam Wang, MD Pediatrician Children s Hospital Colorado

Duties of Advisory Committee Systematically review the scientific literature Come to consensus on population health effects of marijuana use Develop public health statements Come to consensus on translation of the science into simplified language Recommend public health related policies Recommend public health surveillance activities Identify research gaps important to public health

Meeting Schedule Date May 12, 2014 June 16, 2014 July 21, 2014 August 18, 2014 September 15, 2014 October 20, 2014 November 17, 2014 December 15, 2014 Topic Committee Introduction Marijuana Use During Pregnancy and Breastfeeding Potential Neurological and Mental Health Effects Potential Health Effects on Youth and Unintentional Poisonings Marijuana Dose and Drug Interactions Potential Extrapulmonary Effects and Injuries Potential Respiratory Effects and Lung Cancer Committee Conclusion

Occupational Health and Safety Workgroup

Growing Marijuana 101 High temperature 71 to 88 F Optimum as high as 95 F Excess heat vented outside High relative humidity 50%-70% High intensity lighting 2,000 lumens/ft2 Controlled photoperiod Elevated carbon dioxide 700 to 1500 ppm Frequent fertilization Pest control (mites & fungi)

IMGO Study Examine 15-20 IMGOs during law enforcement entry Determine the exposures associated with the investigation of IMGOs Determine the potential adverse health effects to first responders and children Suggest appropriate PPE for first responders

Potential Health & Safety Hazards Illegal MGOs Concealed operation Inadequate ventilation Excessive moisture Makeshift carbon dioxide concentrator Improper electrical installation Limited knowledge of safe pesticide and fertilizer handling Growers and family live in house

IMGO Study In 21/30 (70%) MGOs, mold at levels classified as IAQ problem During tear-out 6/10 (60%) MGOs mold increased compared to initial samples Mold levels during plant removal activities were similar to those that would be expected during a medium size mold remediation job.

Study Conclusions Significant mold exposure hazard at most MGOs Allergic symptoms, asthma exacerbation, special considerations for immunosuppressed individuals Combustion pollutants were not a significant issue in Colorado MGOs, but remain an acute exposure concern. Pesticide use in Colorado MGOs was very limited Significant potential for irritation symptoms from volatile organic compounds Most surfaces in an MGO are contaminated with significant levels of THC Use of respiratory protection and gloves is an important practice for investigators

How do results scale to larger manufacturing? Not a concealed operation More ventilation Much larger, more plants, more chemicals More workers Extractions? Security issues

OHSW: Goals Identify EHS issues in the marijuana industry Provide guidance to marijuana industry to prevent occupational injuries and illnesses Provide guidance to marijuana industry on hazardous waste and sustainability issues Identify best practices for nuisance odor control and remediation of former grow operations Identify surveillance data to follow injury and illness trends

OHSW: Participation Multiple CDPHE divisions Colorado School of Public Health Center for Worker Health and Environment Colorado State University Local health departments Private consultants Industry representatives Federal agencies

Sub Groups Existing industry knowledge Industrial Hygiene Safety and Security Wellness and Safety Culture Occupational Medicine Local and Environmental Health Issues Information Dissemination

Anticipated Outputs EHS guide for the marijuana industry Surveillance report on occupational injuries and illnesses in the marijuana industry Marijuana industry meeting to share findings

Current Educational Efforts www.colorado.gov/marijuana

Questions?