RCGP and Cancer Research UK Workshop. Hilton Newcastle Gateshead, Bottle Bank, Gateshead, NE8 2AR 13 th July 2017

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Hilton Newcastle Gateshead, Bottle Bank, Gateshead, NE8 2AR 13 th July 2017 Dr Richard Roope RCGP and Cancer Research UK Cancer Clinical Champion Senior Clinical Advisor Cancer Research UK

How can GPs help prevent skin cancer? When to excise in clinic and what are the risks? GPs involvement with follow-up care NG12 NICE guidelines

Prevention

Prevention

What proportion of all cancers are preventable? 1. 28% 2. 32% 3. 38% 4. 42% 5. 48%

What proportion of all cancers are preventable? 1. 28% 2. 32% 3. 38% 4. 42% 5. 48%

Prevention What proportion of melanomas are preventable? 1. 66% 2. 76% 3. 86% 4. 96% 5. 100%

Prevention What proportion of melanomas are preventable? 1. 66% 2. 76% 3. 86% 4. 96% 5. 100%

Prevention Number Lung 39594 Bowel 22454 Breast 13577 Melanoma 11479 Oropharyngeal 8488 Oesophagus 7415 Stomach 5317 Bladder 4368 Kidney 4260 Pancreas 3246 Endometrial 3136 Cervix 3064 Liver 1826 Ovary 1494 Leukaemia 1292 Others 8214 Total 139225

Prevention Number Preventable% Lung 39594 89% Bowel 22454 54% Breast 13577 27% Melanoma 11479 86% Oropharyngeal 8488 93% Oesophagus 7415 89% Stomach 5317 75% Bladder 4368 42% Kidney 4260 42% Pancreas 3246 37% Endometrial 3136 37% Cervix 3064 100% Liver 1826 42% Ovary 1494 21% Leukaemia 1292 15% Others 8214 9% Total 139225 42% http://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type

http://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type RCGP and Cancer Research UK Workshop Prevention

http://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type RCGP and Cancer Research UK Workshop Number Preventable% Lung 39594 89% Bowel 22454 54% Breast 13577 27% Melanoma 11479 86% Oropharyngeal 8488 93% Oesophagus 7415 89% Stomach 5317 75% Bladder 4368 42% Kidney 4260 42% Pancreas 3246 37% Endometrial 3136 37% Cervix 3064 100% Liver 1826 42% Ovary 1494 21% Leukaemia 1292 15% Others 8214 9% Number Preventable% Cervix 3064 100% Oropharyngeal 8488 93% Lung 39594 89% Oesophagus 7415 89% Melanoma 11479 86% Stomach 5317 75% Bowel 22454 54% Bladder 4368 42% Kidney 4260 42% Liver 1826 42% Pancreas 3246 37% Endometrial 3136 37% Breast 13577 27% Ovary 1494 21% Leukaemia 1292 15% Others 8214 9% Total 139225 42% Total 139225 42%

http://www.nature.com/bjc/journal/v111/n5/full/bjc2014364a.html

http://www.nature.com/bjc/journal/v111/n5/full/bjc2014364a.html

Sunbeds

Sunbeds - cause 4% of all melanomas (100 deaths per year)

Sunbeds - use under age of 35 melanoma risk 59%

Sunbeds What is the legal minimum age to use commercial sunbeds? 1. 12 2. 16 3. 18 4. 21 5. No legislation

Sunbeds What is the legal minimum age to use commercial sunbeds? 1. 12 2. 16 3. 18 (April 2011) 4. 21 5. No legislation Sunbeds (Regulation) Act 2010

When to excise?

When NOT to excise? Suspected melanoma Aged 24 years or younger Immunosuppressed Gorlin syndrome(naevoid basal cell carcinoma syndrome)

When NOT to excise? is a recurrent BCC following incomplete excision is a persistent BCC that has been incompletely excised according to histology is morphoeic, infiltrative or basosquamous in appearance

When NOT to excise? Is located: over important underlying anatomical structures (for example, major vessels or nerves) in an area where primary surgical closure may be difficult (for example, digits or front of shin) in an area where difficult excision may lead to a poor cosmetic result at another highly visible anatomical site (for example, anterior chest or shoulders) where a good cosmetic result is important to the patient.

When NOT to excise? The lesion: is located below the clavicle (that is, not on the head or neck) is less than 1 cm in diameter with clearly defined margins https://www.nice.org.uk/guidance/csgstim/evidence/improving-outcomes-forpeople-with-skin-tumours-including-melanoma-update-the-management-oflowrisk-basal-cell-carcinomas-in-the-community-2010-partial-guidance-update2

Who can excise?

Who can excise? GPs performing skin surgery on low-risk BCCs should: demonstrate competency in performing local anaesthesia, punch biopsy, shave excision, curettage and elliptical excision using the direct observation of procedural skills (DOPS) assessment tool in the Department Health Guidance for GPwSIs in dermatology and skin surgery and then follow a program of revalidation have specialist training in the recognition and diagnosis of skin lesions appropriate to their role.

GPs performing skin surgery on low-risk BCCs should: send all skin specimens removed to histology for analysis provide information about the site of excision and provisional diagnosis on the histology request form maintain a fail-safe log of all their procedures with histological outcome to ensure that patients are informed of the final diagnosis, and whether any further treatment or follow-up is required https://www.nice.org.uk/guidance/csgstim/evidence/improving-outcomes-forpeople-with-skin-tumours-including-melanoma-update-the-management-oflowrisk-basal-cell-carcinomas-in-the-community-2010-partial-guidance-update2

GPs performing skin surgery on low-risk BCCs should: provide quarterly feedback to their CCG on the histology reported as required by the national skin cancer minimum dataset, including details of all proven BCCs provide details to their CCG of all types of skin cancer removed in their practice as described in the 2006 NICE guidance on skin cancer services and should not knowingly remove skin cancers other than low-risk BCCs https://www.nice.org.uk/guidance/csgstim/evidence/improving-outcomes-forpeople-with-skin-tumours-including-melanoma-update-the-management-oflowrisk-basal-cell-carcinomas-in-the-community-2010-partial-guidance-update2

GPs performing skin surgery on low-risk BCCs should: provide evidence of an annual review of clinical compared with histological accuracy in diagnosis for the low-risk BCCs they have managed attend, at least annually, an educational meeting (organised by the Skin Cancer Network Site Specific Group), which should: present the 6-monthly BCC network audit results, including a breakdown of individual practitioner performance include one CPD session (a total of 4 hours) on skin lesion recognition and the diagnosis and management of low-risk BCCs be run at least twice a year. https://www.nice.org.uk/guidance/csgstim/evidence/improving-outcomes-forpeople-with-skin-tumours-including-melanoma-update-the-management-oflowrisk-basal-cell-carcinomas-in-the-community-2010-partial-guidance-update2

OR as locally agreed!

Melanoma generally done in Secondary Care Wound check Para-wound check for recurrence General skin check Sunsmart advice

Risk of second skin cancer within 5 years First Skin Cancer Diagnosed Second skin cancer MM SCC BCC Other cancers MM 10% 5% 13% 18% SCC 15% - 74% 17% BCC 62% 92% - 62% Other cancers 13% 2% 2% 3% Data derived from South West Public Health Observatory

Diagnosis

Diagnosis Which diagnostic tool do you use? 1. Don t use one 2. ABCD 3. ABCDE 4. 7 point check list 5. 7 point weighted check list

Diagnosis Which diagnostic tool do you use? 1. Don t use one 2. ABCD 3. ABCDE 4. 7 point check list 5. 7 point weighted check list

Where are they? http://www.cancerresearchuk.org/healthprofessional/cancer-statistics/statistics-by-cancertype/skin-cancer/incidence#heading-four

NG12 Refer via 2 week cancer pathway:

NG12 Refer via 2 week cancer pathway: Score of 3 or more on 7 point weighted check list: Major features (2 points each): Change in size Irregular shape Irregular colour Minor features (1 point each) 7+mm diameter (largest) Inflammation Oozing Change in sensation

NG12 Refer via 2 week cancer pathway: Dermoscopy suggests melanoma Skin lesion with appearance of nodular melanoma

NG12 Refer via 2 week cancer pathway: Suspicion of squamous cell carcinoma

NG12 Refer via routine pathway: Suspicion of basal cell carcinoma Refer via 2 week cancer pathway: BCC, if there is particular concern that a delay may have a significant impact, because of factors such as lesion site or size

NG12 Follow NICE 2010 on management of low risk BCCs in the community for advice as to who should excise suspected BCCs

Final Tips

Final Tips Nodular melanomas can be rapidly growing and mimic SCCs or pyogenic granulomas

Final Tips Nodular melanomas can be rapidly growing and mimic SCCs or pyogenic granulomas

Final Tips Melanomas are rare before puberty

http://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/skincancer/incidence#heading-one RCGP and Cancer Research UK Workshop Final Tips Melanomas are rare before puberty

Final Tips Melanomas are rare in Black and Asian patients

Final Tips Be wary of the ugly duckling:

Final Tips Be wary of the ugly duckling: Grob JJ, Bonerandi JJ. The 'ugly duckling' sign: identification of the common characteristics of nevi in an individual as a basis for melanoma screening. Arch Dermatol 1998;134(1):103-104.

Final Tips Be wary of the ugly duckling: What is the 7PWS? Changing size Nothing to feel No oozing http://www.doctors.net.uk/eclient/cruk/cruk _skin_toolkit_2014/red-flag4.html

Score of 3 or more on 7 point weighted check list: Final Major Tips features (2 points each): Change in size Be wary Irregular of the shape ugly duckling: What is the 7PWS Irregular colour Minor features (1 point each) 7+mm diameter (largest) Inflammation Oozing Change in sensation Changing size Nothing to feel No oozing http://www.doctors.net.uk/eclient/cruk/cruk _skin_toolkit_2014/red-flag4.html

Final Tips What is the 7PWS 1. 3 2. 5 3. 7 4. 9 5. 11 Vote now

Final Tips What is the 7PWS 1. 3 2. 5 3. 7 4. 9 5. 11 Vote now

Score of 3 or more on 7 point weighted check list: Final Major Tips features (2 points each): Change in size Be wary Irregular of the shape ugly duckling: What is the 7PWS Irregular colour Minor features (1 point each) 7+mm diameter (largest) Inflammation Oozing Change in sensation REFER via 2WW Changing size Nothing to feel No oozing http://www.doctors.net.uk/eclient/cruk/cruk _skin_toolkit_2014/red-flag4.html

Final Tips Be wary pigmented lesion on finger or sole of foot: Acral lentiginous melanoma on the toe http://www.doctors.net.uk/eclient/cruk/cruk _skin_toolkit_2014/red-flag5.html

Final Tips If in doubt check it out:

Useful links:

Useful links: doctors.net.uk cruk.org.uk sunsmart.org.uk bad.org.uk Dermnet.nz Swpho.nhs.uk/skincancerhub rcgp.org.uk/clinical-and-research/toolkits/primary-carecancer-toolkit.aspx

Which was the most eye catching update?

Which was the most eye catching update? 1. Preventability of melanoma 2. Sunbed minimum legal age 3. Criteria to remove low risk BCCs 4. 7 point weighted check list 5. NICE Guidance 6. Ugly Duckling sign 7. Something else

ANY QUESTIONS?