Circulatory System Objective sheet 3

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Circulatory System Objective sheet 3 10. Functions of blood 1) Transport oxygen and nutrients 2) Transport of carbon dioxide and waste 3) Protection against disease causing micro-organisms 4) Clotting of blood vessels to prevent blood loss 5) Distributes heat and maintains body temperature 6) Maintenance of ph of bodily fluids 7) Transport of hormones 8) Maintenance of water and ion concentration of bodily fluids 11. Chambers, valves, vessels in the heart Atrioventricular valve Bicuspid Semilunar valve Semilunar valve Atrioventricular valve Tricuspid Septum * See table on following page for functions * See Arrows for blood flow

Structure Inferior vena cava Superior vena cave Right Atrium Tricuspid valve (atrioventricular valve) Right Ventricle Semilunar valve Pulmonary trunk/pulmonary arteries Pulmonary veins Left atrium Bicuspid valve (atrioventricular valve) Left ventricle Aorta Septum Pericardium Function` Carries deoxygenated blood to the heart. From the lower body. Carries deoxygenated blood to the heart from the upper body Hollow chamber that receives deoxygenated blood from the body Prevents the back flow of blood into the atria when the ventricles contract Hollow chamber that pumps deoxygenated blood to the pulmonary artery to the lungs Prevents the back flow of blood into the ventricles when it pumps Carry deoxygenated blood from the right ventricle to the lungs Carry oxygenated blood from lungs to left atria Receives oxygenated blood from the lungs (via the pulmonary veins) Prevents the back flow of blood into the atria when the ventricles contract Pumps oxygenated blood to the body via the aorta Carries oxygenated blood to the body Separates left and right ventricles The membrane which encloses the heart, it holds the heart in place and prevents over stretching. 13. Distinguish between the pulmonary circulation and systemic circulation Pulmonary system Passage of blood from the heart to the lungs to the heart Role > To remove CO2 from the blood > Pick up O2 Systemic system Passage of blood from heart to organs/tissues to heart Role > Deliver O2 > Collect CO2 Deoxygenated Lungs Oxygenated Pulmonary System Heart Deoxygenated Body Oxygenated Systemic System

14. Stages of the Cardiac Cycle Sequence of events in one complete heart beat 2 Parts Systole Chamber contracts Pushes blood out of chamber Diastole Chamber relaxes Chamber fills with blood Both sides of the heart contract at the same time, the average heart beat takes 0.8secs Meaning the average heart rate is 72 bpm 1) Atrial Systole - Forces blood through the AV valves into ventricles Ventricular Diastole - Ventricle fills with blood Takes around 0.1 seconds 2) Ventricular systole - Forcing the blood out of the ventricles into arteries through the semilunar valve AV valve slams shut - Creating the lub part of the heart beat Atrial diastole - Atria filling with blood Takes around 0.3 seconds 3) Atrial and Ventricular Diastole - Relaxed and filling with blood - dub sound of heart beat Semilunar valve slams shut - Elastic recoil of arteries forces it to close Takes around 0.4 seconds

15/16. Components of the blood Plasma (55%) - 91% water - 9% dissolved substances (nutrients and ions) Formed elements (45%) - Erythrocytes: Red blood cells - Leucocytes: White blood cells - Thrombocytes: Platelet Formed elements Drawing/ Description Role Timespan Other Erythrocytes Red Blood Cells Biconcave discs, thinner in the middle than at the edges Haemoglobin combines with oxygen and transports it to cells around the body. Collects CO 2 for transportation out of the body 120 days - Produced in the bone marrow - Destroyed in the liver and spleen - No nucleus more room for haemoglobin - High Surface Area Leucocytes White Blood Cells Granulocytes Have a granular cytoplasm and lobed nucleus Remove dead or injured cells and invading microorganisms From a few minutes to years - Larger but fewer than Erythrocytes Monocytes Lymphocytes, spherical nucleus a-granular cytoplasm Thrombocytes Platelets Small cell fragments 1/3 of the size of an erythrocyte Clot blood and prevent excessive bleeding 7 Days - No nucleus - Formed in red bone marrow 17. Transport of O 2 3% is carried in solution in plasma 97% carried in erythrocytes- Haemoglobin: Iron, Globular protein Hb + O 2 < > HbO 2 Haemoglobin + O 2 < -> Oxyhaemoglobin > High Concentration of O 2 (alveoli in lungs) < Low Concentration of O 2 (Respiring body tissues) 17. Transport of CO 2 7-8%- dissolved in plasma 22%- combines with the protein (globin) part of haemoglobin

Carbon dioxide + haemoglobin < > Carbaminohemoglobin 70% - HCO 3 - - Bicarbonate ions in plasma CO 2 + H 2 O < > H 2 CO 3 Carbonic Acid < > H + + HCO 3 - (Dissociates) -> At respiring cells < At Alveoli Other things transported in the blood Metabolic waste- Urea Organic nutrients- Glucose, Vitamins Ions- Na+, Ca 2+, K +, Cl- 18. How are nutrient and water transported in the blood? Nutrients is dissolved in the plasma and then pass out through the 1 cell thick capillary walls. 19. Arteries, Arterioles, Veins, Venules, Capillaries Capillary Vein Artery Connect Arteries and veins Carry blood towards the heart Carry blood away from the heart Carry deoxygenated and oxygenated blood Carry deoxygenated blood Carry Oxygenated blood No Valves Valves to stop back flow of blood No Valves Walls are very thin Thin layer of muscle Have a thick layer of muscle Tiny vessels in close contact to cells Low blood pressure and slow speed to allow exchange of materials More space inside Blood flows at constant pressure Less space inside Blood flows at changing pressure due to the action of the heart

Arteries Vaso consctriction - Muscles in arteries restrict blood flow to organs - Change blood flow on the basic needs of the body Vaso dilation - Muscles in arteries dilate to allow more blood flow to organs - Change blood flow on the basic needs of the body 20. The relationship between the circulatory system and respiratory system Respiratory system supplies the blood with oxygen in order for the blood to deliver it to all parts of the body. Circulatory System transports blood and oxygen from the lungs to tissues in the body. 21. Functions - Drain away excess tissue fluid and return it to your circulatory system - To defend the body again diseases caused by microorganisms (bacteria and Viruses) 22. Components of the lymphatic system As blood enters the capillaries it has high pressure, forcing some fluid through the capillary walls into tissue Blind ended lymph capillaries - Larger and more permeable than blood capillaries - Epithelial tissue - Remove excess tissue fluid Lymph Vessels - Merged lymph capillaries Lymph nodes/glands - Found along the vessels - Found in neck, armpits, groin - Surrounded by connective tissue - Phagocytic cells in the lymph nodes destroy the particles though phagocytosis, they engulf the infectious cells - When infections occur they swell and become tender Lymph ducts - Lymph drains back into the circulatory system * 1 way system * No pump (ie. Heart) * Have valves

Circulatory system Distributes oxygen and nutrients to entire body Closed continuous loop, via arteries, capillaries and veins Blood is pumped by heart Blood consists of plasma, red and white blood cells Blood is filled by kidney Lymphatic systen Responsible for removing excess tissue fluid from the tissues Blind ended, open circuit from tissues to lymph vessels to veins in one direction Lymph is passively moved by contraction of muscles Lymph is excess tissue fluid and other wastes and white blood cells Lymph is filtered by lymph nodes