Characteristics of individuals who are HIV-positive, out of HIV care, and newly diagnosed with Sexually Transmitted Infections

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Characteristics of individuals who are HIV-positive, out of HIV care, and newly diagnosed with Sexually Transmitted Infections 2014-2016 New York City Department of Health and Mental Hygiene Bureau of Sexually Transmitted Disease Control Research and Evaluation Unit

HIV Treatment = HIV Prevention Framework Individuals adherent to ARTs w/ an undetectable viral load cannot transmit HIV to others Test and Treat strategy ART initiation immediately after diagnosis decreases community viral load & reduce rate of new infections Need for retention-in-care and ART adherence support 2017, August 15. Treatment as Prevention for HIV. Retrieved from https://www.avert.org/professionals/hiv-programming/prevention/treatment-asprevention

Objectives 1. Determine the characteristics of persons who are not engaged in HIV care. 2. Determine the characteristics of out of care (OOC) individuals that facilitate successful re-engagement in HIV care.

History of the NYC HIV Epidemic

People Living with HIV/AIDS (PLWHA) in NYC and Presumed Living as of December 31, 2015 121,616 PLWHA 28% Women (34,111) 72% Men (87,505) 54% MSM (47,432) 30% African-American (14,416) 30% Hispanic (14,073)

NYC STI Diagnoses in 2015

Gonorrhea (GC) Diagnoses in NYC, 2015 Cumulative Gonorrhea Cases There were 16,913 gonorrhea (GC) cases in 2015. Among those cases 73% (12,262) were men. This equals a case rate of 302.9 per 100,000. GC Cases by Age 76% of 2015 male GC cases were between the ages 20-39. GC Cases by Race/Ethnicity 45% (5,476) of male cases were among Black and Hispanic men. The New York City Department of Health and Mental Hygiene Bureau of Sexually Transmitted Disease Control Quarterly Report Vol. 14, No. 4 December 2016.

Syphilis Diagnoses in NYC, 2015 Syphilis Cases In 2015, there were 6,343 total syphilis cases. 90% (5,680) cases were among men. Syphilis Cases among Men 1,521 Primary & Secondary syphilis cases. Male Cases Interviewed 966 (64%) were interviewed for Primary and Secondary syphilis. 79% (766) of cases interviewed reported engaging in sex with men (MSM). Interviewed MSM Among the 766 MSM interviewed 49% were living with HIV. The New York City Department of Health and Mental Hygiene Bureau of Sexually Transmitted Disease Control Quarterly Report Vol. 14, No. 4 December 2016.

NYC Partner Services Program

Overview of Partner Services 8 Sexual Health Centers located in four boroughs: Brooklyn Bronx Manhattan Queens 76 Partner Services Staff

BSTDC Partner Services Staff Disease Intervention Specialist Patients diagnosed with a STI at a BSTDC clinic Public Health Advisors Individuals diagnosed with a STI by an outside provider Community-based Organization Public Hospital Private Provider

Criteria for Conducting Partner Service Interviews for HIV+ Diagnoses HIV+ Diagnosis Newly Diagnosed at BSTDC clinic Prevalent infection with new interviewable STI Interviewable STI Diagnoses Syphilis Pregnant women Neuro/Ocular symptoms Male w/ female partners Other criteria based on reactor grid Gonorrhea Reduced susceptibility

Assessment of OOC Status Self-reported HIV-care status during interviews Not based on HIV surveillance or provider confirmations Documented in MAVEN Partner Services staff conduct re-linkage activities Offers referrals Verify linkage-to-care

Characteristics of HIV+ OOC Patients

Demographics of HIV+ OOC Patients, 2014-2016 116 prevalent HIV+ individuals diagnosed with incident STI s Male = 111 Female = 2 Transgender = 3 Sexual Health Center patients OR cases reported to BSTDC surveillance or by an outside providers Investigated by 50 Partner Services staff Following analyses consists of individuals who identified their current gender as MALE

Demographics of Previously Diagnosed HIV-Positive Males with Incident STI Infections, 2014-2016 (n=111) 70% 60% 50% PERCENT 40% 30% 20% 10% 0% Race/Ethnicity Age Group Sexual Identity

Characteristics of Previously Diagnosed HIV-Positive Males with Incident STI Infections, 2014-2016 (n=111) 90% 80% 70% 60% PERCENT 50% 40% 30% 20% 10% 0% STI Diagnoses Number of STI Diagnoses per patient Illicit drug use w/n last 12 months Length of time living with HIV/AIDS

Characteristics of Previously Diagnosed HIV-Positive Males with Incident STI Infections, 2014-2016 (n=111) 60% 50% 40% PERCENT 30% 20% 10% 0% Sex with anonymous partners w/n last 12 months Sex with internet partners w/n last 3-12 months Borough of Residence

Characteristic of Male Patient's Sex Partners, 2014-2016 (N=111) 60% 50% 40% PERCENT 30% 20% 10% 0% 0 partners 1-3 partners 4 partners Missing 0 partners 1-3 partners 4 partners Missing Total male sex partners w/n past 12 months Total female sex partners w/n past 12 months

Combination of STI Diagnoses among HIV-Positive Previously Diagnosed Male Patients, 2014-2016 (N=111) Single Diagnosis n % Early Syphilis 46 41% Late Syphilis 33 30% Gonorrhea 10 9% Chlamydia 0 0% Two Diagnoses Early Syphilis & Gonorrhea 8 7% Early Syphilis & Chlamydia 3 3% Late Syphilis & Gonorrhea 6 5% Late Syphilis & Chlamydia 1 1% Gonorrhea & Chlamydia 3 3% Three Diagnoses Early Syphilis, Gonorrhea and Chlamydia 1 1% Latent Syphilis, Gonorrhea and Chlamydia 0 0% Early Syphilis = Primary Syphilis (710); Secondary Syphilis (720); Early latent Syphilis (730) Late Syphilis = Late latent Syphilis (745)

Males Referred and Re-linked to Medical Care, 2014-2016 (N=111)

Multivariate Analysis of Characteristics of Males Referred-to-Care, 2014-2016 Race/Ethnicity Age Sexual Identity Number of STI Diagnoses per patient Illicit drug use w/n past 12 months Length of time living with HIV/AIDS Total number of attempts to contact individuals STI Diagnoses Total male sex partners w/n past 12 months Total female sex partners w/n past 12 months Sex with anonymous partners w/n past 12 months Sex with internet partners w/n past 12 months Borough of residence

Characteristics of Males who were successfully Referred-to-Care, 2014-2016 Characteristics significantly associated with referral to care among male BSTDC patients, (N=111) Characteristics Referred to care Length of time living with HIV/AIDS prior to STI diagnosis AOR CI P-value 2 years or more ref 1-2 years 1.51 0.32-7.2 0.61 Less than 1 year 3.21 1.29-7.99 0.01* *p <0.05

Linkage-to-care Characteristics of Males, 2014-2016 100% 90% 80% 70% PERCENT 60% 50% 40% 30% Linked to care (n=13) Not linked to care (n=14) 20% 10% 0% Age Group Length of time living with HIV/AIDS prior to STI diagnosis STI Diagnoses Attempts to verify linkage-to-care

Conclusion Men living with HIV Males diagnosed w/n one year of STI infection were most likely to accept a referral to care. Men living with HIV and LTC Over 90% of those living with HIV less than a year were linked-to-care. Successful LTC Partner Services (PS) staff were only able to verify successful LTC for 22% of those referred. Successful Linkage Linakge-to-care was highest among men 30-39 years old STI Diagnoses Linakge to care was more successful among men who were diagnosed with syphilis

Programmatic Implications Documentation is key! Surveillance data is incomplete Partner Services staff time is valuable Quality vs. Quantity of attempts to contact Assess difference in documented LTC outcomes with new program model

Thanks! ANY QUESTIONS? You can find me at: Dfields5@health.nyc.gov

Credits New York City Department of Health and Mental Hygiene- Bureau of Sexually Transmitted Disease Preventions and Control Centers for Disease Control Case Investigation & Partner Services Staff Dr. Susan Blank Dr. Preeti Pathela

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