International scientific-practical conference «Management of Peritoneal Surfaces Malignancy» Irkutsk, August 9-11, Program

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Day 1 Program Wednesday, 9 of August, 2017 Regional Oncology Center, Irkutsk Conference Hall 8.00-8.30 Registration of participants 8.30-8.50 Opening conference Welcome Gouverneur (Sergey Levchenko) Welcome Minister of Health (Oleg Yaroshenko) Welcome Head of Center (Viktoriya Dvornichenko) Welcome Chair KMF (Helmut Hahn) 8.50 Introduction Chair of Work Shop (Beate Rau) CHAIR: Professor Viktoria Dvornichenko \ Professor Beate Rau 9.40 10.10 10.40 11.10-11.40 History and evoluation of CRS and HIPEC Paul Sugarbaker, Director of Surgical Oncology, Cancer Institute at Washington Hospital Center, Washington DC, U.S. Overview of International guidelines for CRS and HIPEC Rationale for pre- and postoperative chemotherapy CRS and HIPEC Coffee break CHAIR: Professor Franҫois Quenet \ Professor Horst-Günter Rau 11.40 12.10 12.40 Preoperative radiological staging: urgent or nice to have? Arkadiy Munkuev, Chief physician x-ray-surgery, Irkutsk Regional Oncology Hospital, Irkutsk, RU Role of staging laparoscopy in case selection Peri-operative risk assessment (nutrional status, Cardiac-, pulmonary-, renal function, eg.) and solutions Verena Müller, Surgical Department Charité, Berlin, DE 13.10 Lunch 14.10 Patient selection and work up for CRS and HIPEC

14.40 Hemodynamic monitoring in CRS and HIPEC: necessary or nice to have? Vladimir Skrypnikov, Dept. of Anesthesiology & Critical Care Medicine, Charité Campus Virchow, Berlin, DE 14.40 Features of intra- and postoperative period by patients with HIPEC on ICU Dmitriy Morikov, Chief physician anesthesia and intensive care unit, Irkutsk Regional Oncology Hospital, Irkutsk, RU 15.20 Making HIPEC safe for patients and staff 15.40 Coffee break CHAIR: Professor Yutaka Yonemura \ Dr. Alexey Shelekhov 16.10 Postoperative care on ICU: Special treatment neccassary? Vladimir Skrypnikov, Dept. of Anesthesiology & Critical Care Medicine, Charité Campus Virchow, Berlin, DE 16.45 Prevention and management of postoperative and chemotherapy-induced complications Beate Rau, Surgical Department Charité, Berlin, DE 16.55 Rationale on metachronous HIPEC after CRS Horst-Günter Rau, Visceral and thoracic surgery at the HELIOS Amper-Klinikum Dachau, DE 17.10 Surgical approach to peritoneal surface malignancy Paul Sugarbaker, Director of Surgical Oncology, Cancer Institute at Washington Hospital Center, Washington DC, U.S. 18.00 Dinner

Day 2 Thursday, 10 th of August, 2017 Regional Oncology Center, Irkutsk Conference Hall CHAIR: Professor Paul Shugarbaker \ Professor Yutaka Yonemura 8.30 Introduktion to Case 1 Aleksei Shelekhov, Deputy chief physician, Irkutsk Regional Oncology Hospital, Irkutsk, RU 8.45 Tactics of treatment of operable metastatic colorectal cancer Rodion Rasulov, Chief of pancreatic and liver tumor department, Irkutsk Regional Oncology Hospital, Irkutsk, RU 9.05 Technology and results of treatment complicated and local advanced forms of rectal cancer Aleksei Shelekhov, Deputy chief physician, Irkutsk Regional Oncology Hospital, Irkutsk, RU 9.25 New treatment options in metastastatic colorectal cancer Elena Artamonova, leading researcher, Blokhin Russian Cancer Research Centre Moscow, RU 9.40 Life OP Case 1 10.00 Ovarectomy in principle? What to take into considarations Christhardt Köhler, Asklepios Hospital, Gynaecology Clinic: Special Surgical and Oncological Gynaecology; Hamburg; DE 10.20 Cholecystectomy, splenectomy per principle? What to take into considerations? 10.45 Overview of technical devices in CRS Horst-Günter Rau, Visceral and thoracic surgery at the HELIOS Amper-Klinikum Dachau, DE 11.00 Кофе-пауза CHAIR: Professor Yan Li \ Profesor Kurt van der Speeten 11.30 Life OP Case 1 11.50 Is prophylactic HIPEC after colorectal cancer surgery the right strategy? 12.10 Early complications

12.25 Life OP Case 1 International scientific-practical conference 12.45 Late complications Verena Müller, Surgical Department Charité, Berlin, DE 13.00 Interactive case discussion on pitfalls in the OR 13.15 Life OP Case 1 Optional: Multiple choice questions (Vadim Gushchin) 13.30 Lunch CHAIR: Dr. Rodion Rasulov \ Professor Franҫois Quenet 14.30 Indication for CRS&HIPEC: Pseudomyoxoma Peritonei Amir Abdulaev, Senior staff scientist, thorax oncology clinic, Blokhin Russian Cancer Research Centre Moscow, RU 15.00 Life OP Case 1 15.30 Indication for CRS&HIPEC: Peritoneal Mesothelioma 16.00 Coffee break 16.50 Prospects for the treatment of metastatic Gastric Cancer Roman Zubkov, Chief of stomach tumor department, Irkutsk Regional Oncology Hospital, Irkutsk, RU 17.10 Targeted therapy in gastric cancer Natalya Besova, Dept. of Surgical Oncology, Blokhin Russian Cancer Research Centre Moscow, RU 17.30 Indication for CRS&HIPEC: Gastric Cancer Yutaka Yonemura, Shizuoka Cancer Center, JP 17.50 Management of complications after extended upper Gl surgery Verena Müller, Surgical Department Charité, Berlin, DE 18.00 Discussion, remarks, questions, tips concerning the life OP Dinner

Day 3 Friday, 11 of August, 2017 Regional Oncology Center, Irkutsk Conference Hall CHAIR: Dr. Alexey Shelecjov \ Professor Yan Li 8.30 Indication for CRS&HIPEC: Ovarian Cancer Christhardt Köhler, Asklepios Hospital, Gynaecology Clinic: Special Surgical and Oncological Gynaecology; Hamburg; DE 8.50 Treatment options local and advanced forms of ovarian cancer Roman Demonov, Gynecology tumor department, Irkutsk Regional Oncology Hospital, Irkutsk, RU 9.10 Indication for CRS&HIPEC: Appendiceal Cancer Yan Li, Department of Peritoneal Cancer Surgery, Beijing Shijitan Hospital of the Capital Medical University, Beijing, CN 9.30 Indication for CRS&HIPEC: Colorectal Cancer Leonid Petrov, Dept. of Surgical Oncology, Hertsen Moscow Oncology Research Institute, RU 10.00 Quality of life after CRS and HIPEC Beate Rau, Surgical Department Charité, Berlin, DE 10.15 How to start a CRS and HIPEC programme Vadim Gushchin, Surgical Oncology at Mercy Medical Center in Baltimore, Maryland, U.S. 10.30 How to process a SOP? 10.45 Coffee break CHAIR: professor Kurt van der Speeten \ Dr. Vadim Gushchin 11.15 Case reports and voting: рак ЖКТ Yutaka Yonemura, Shizuoka Cancer Center, JP 11.30 Case reports and voting: колоректальный рак 11.45 Case reports and voting: мезотелиома Yan Li, Department of Peritoneal Cancer Surgery, Beijing Shijitan Hospital of the Capital

Medical University, Beijing, CN 12.00 Case reports and voting: Appendiceal cancer 12.15 Case reports and voting: Ovarian cancer Christhardt Köhler, Asklepios Hospital, Gynaecology Clinic: Special Surgical and Oncological Gynaecology; Hamburg; DE 12.30 Case reports and voting: rare cancer 12.45 Farewell, Conclusions, Evaluation, Certificates Professor Viktoria Dvornichenko, Head of Regional Oncology Hospital Irkutsk, RU Professor Beate Rau, Dept. of General, Visceral, Vascular, and Thoracic Surgery, Charité Campus Virchow, Berlin, DE