Annual Conference of the Canadian Blood and Marrow Transplant Group. June 11 to 14, 2014 The Westin Nova Scotian 1181 Hollis Street Halifax, NS

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Annual Conference of the Canadian Blood Preliminary Program In conjunction with the Canadian National, Canadian Apheresis Group, Society, and Vector CBMTG Head Office Malachite Management Inc 375 West 5th Avenue Suite 201, Vancouver BC Canada V5Y 1J6 T. 604.874.4944 F. 604.874.4378 Email: cbmtg@malachite-mgmt.com Web: www.cbmtg.org

Canadian Blood (CBMTG) The Canadian Blood is a national, voluntary, and multi-disciplinary organization providing leadership and promoting excellence in patient care, research, and education in the field of blood and marrow transplant (BMT). CBMTG believes that every patient has a right to the highest standards of care that can be provided by blood and marrow transplant professionals in Canada. Our vision is that Canada will be the best place in the world to have a blood and marrow transplant. Our mission is to be the voice of experts working in the field of blood and marrow transplant. The organization leads education and research across the Canadian BMT field. CBMTG holds an annual conference, organizes free webinars for its members, has a robust clinical trials program and has led the development of the national BMT registry. The Conference Planning Committee, led by Dr. Stephen Couban, has created a scientific program highlighting presentations on topics of interest in the field of BMT. This program was designed for a multidisciplinary audience and topics were chosen with care. CBMTG sessions will be organized from Thursday, June 12 to Saturday June 14, 2014. Canadian National (CNTRP) The Canadian National (CNTRP) is a national initiative designed to increase organ and tissue donation in Canada and enhance the survival and quality of life of Canadians who receive transplants. The program is led by Drs. Lori West at the Alberta Transplant Institute at the University of Alberta in Edmonton and Marie Josée Hébert at the Université de Montréal and brings together 116 investigators at 21 institutions from across Canada to carry out research and develop resources to help Canadians waiting for a tissue or organ transplant. The Society will host sessions Tuesday, June 10 to Thursday, June 12, 2014. Canadian Apheresis Group (CAG) The Canadian Apheresis Group was formed in 1980. The group includes representatives from approximately 40 apheresis units in 19 major medical centers in Canada. At the annual meeting of the CAG we focus on new evidence and techniques for plasma exchange, and also carry out a centre-bycentre review. The society will host sessions Friday, June 13, 2014 to Sunday, June 15, 2014. Society (CHS) The Society represents all physicians and scientists with an interest in the discipline in Canada. At present there are over 280 members. The Society will host a combined session with the CBMTG on Friday, June 13, 2014 from 9:00 am 12:00 pm Venous Thrombosis Clinical Trials Organisation (VECTOR) VECTOR is a collaborative group of thrombosis physicians from various cities in Canada (Ottawa, Montreal. Halifax, Hamilton, Saskatoon, London) who discuss current and new research ideas in the area of thrombosis. The VECTOR members are expected to help the progress of multi-centre academic projects awarded to individual group members. The executive meets via teleconference on a monthly basis to discuss the group s operations and face-to-face up to four times a years (rotating facility hosting the meetings). The Society will host a combined session with the CBMTG on Friday, June 13, 2014 from 9:00 am 12:00 pm CBMTG Head Office Malachite Management Inc 375 West 5th Avenue Suite 201, Vancouver BC Canada V5Y 1J6 T. 604.874.4944 F. 604.874.4378 Email: cbmtg@malachite-mgmt.com Web: www.cbmtg.org

Preliminary Program Tuesday, June 10, 2014 12:00pm 5:00pm CNTRP Meetings Wednesday, June 11, 2014 9:00am 5:00pm CNTRP Meetings Main Session located in Harbour AB, Breakout Rooms TBD 4:00pm 9:00pm Conference Registration Coat Check Thursday, June 12, 2014 7:00am 7:00pm Conference Registration Coat Check Session 1: CBMTG-CNTRP Joint Session Facing a common enemy, viral infections in SOT and AHCT Moderator: Marie-Josée Hébert, MD, FRCPC 8:00am Welcome by the CBMTG and CNTRP: Building bridges between the SOT and BMT scientists where we are after 1 year Silvy Lachance, MD, FRCPC, CSPQ, Marie-Josée Hébert, MD, FRCPC 8:40am: Viral infections: From bench to beside 8:00am 11:00am Atul Humar, MD, FRCPC 9:10am: Risk prediction tools based on viral-host interactions that predispose young SOT and HSCT patients to EBV Upton Allen, MBBS, MSc, FAAP, FRCPC 9:40am: Adoptive T-cell immunotherapy to treat and prevent virus-related complications post-transplantation Jean-Sébastien Delisle, MD, PhD 10:10am 10:30am Health Break in the Atlantic Ballroom (see below) 10:30am: Interactive session: Engaging the HSCT and SOT communities within the CNTRP Steven Paraskevas, MD, PhD, Lori West, MD, PHD, Kirk Schultz, MD 10:10am 10:30am Health Break Atlantic Ballroom 11:00am 1:00pm Symposium #1: Lunch 1:00pm 4:00pm Session 2A: Clinical Trials Network Meeting Moderator: Donna Wall, MD Session 2B: Multidisciplinary Allied Health Maritime Room Moderator: Jo-Ann Edwards, NP, Gertrude Kells, RN Access to high cost treatments: Navigating the complex world of oncology drug coverage Mary Lou Robertson, BA, BSW, RSW Near Death Experiences: Hope, Hypoxia, and Hypthesis David Maginley, M. Div Aprepitant in blood and marrow transplantation: To add or not to add? Lina Ho, BScPhm, RPh, ACPR The use of Thiotepa in preparative regimens for hematopoietic cell transplantation Philippe Bouchard, BPharm, MSc, BCOP Session 2C: Laboratory Technologists Lunenburg Room Moderator: Angeline Giftakis, MLT, Giovanna Cameron ISBT 128: From a global picture to the details Pat Distler, MS, MT(ASCP)SBB ISBT 128 product code selection: Which codes do I want? Which codes do I need? Leigh Sims-Poston, BS, MT(ASCP) Getting the most out of your ISBT technology partners Geoffrey Browne 3

Thursday, June 12, 2014 4:00pm 4:15pm 4:15pm 6:15pm Health Break and Poster Group 1 Presentations Health break located in Atlantic Ballroom, Poster group presentations located in Session 3: CBMTG National Registry Steering Meeting Moderator: Kristjan Paulson, MD 6:15pm 7:30pm Welcome Reception with Exhibits Atlantic Ballroom and Foyer Friday, June 13, 2014 7:00am 7:00pm Conference Registration Coat Check 7:30pm 8:45am Symposium #2: Breakfast 9:00am 12:00pm 10:00am 10:20am Session 4: Joint Session CBMTG, CHS, Vector Moderators: Stephen Couban, MD, Joanne Hickey, MD, FRCPC 9:00am: Human bone marrow failure: New treatment and new pathophysiologies Neal Young, MD 10:00am 10:20am Health Break in the Atlantic Ballroom (see below) 10:20am: Thrombosis and Malignancy: Management of complicated cases Sudeep Shivakumar, MD, FRCPC, Marc Carrier, MD, MSc, FRCPC 11:10am: Overview of PNH Daniéle Marceau, MD Health Break and Poster Group 2 Presentations Health break located in Atlantic Ballroom, Poster group presentations located in 12:00pm 2:00pm Symposium #3: Lunch 2:00pm 3:30pm 3:30pm 4:00pm Session 5A: Age and Transplant Moderator: Gizelle Popradi, MD, Jo-Ann Edwards, NP 2:00pm: 2:45pm: Allogeneic transplant for older AML patients: Too little or too much? Andrew Artz, MD, MS Case study: Compliance, fertility, and comorbidities Speaker TBD Session 5B: CAG Nursing Session Health Break and Poster Group 3 Presentations Health break located in Atlantic Ballroom, Poster group presentations located in 4

Friday, June 13, 2014 Session 6: Choosing the Best Donor 4:00pm 6:00pm Moderators: Andrea Kew, MD, Marie Tulloch, MLT 4:00pm: 4:20pm: 4:40pm: 5:00pm: How do we build the best registry? Mindy Goldman, MD, FRCPC Donor selection: Optimizing clinical outcomes and donor safety John Miller, MD, PhD KIR typing and its clinical relevance Wing Leung, MD, PhD Case Studies Mindy Goldman, MD, FRCPC, John Miller, MD, PhD, Wing Leung, MD, PhD 6:00pm 7:00pm CBMTG Annual General Meeting 7:00pm 8:30pm Symposium #4: Dinner Saturday, June 14, 2014 7:00am 7:00pm Conference Registration Coat Check 7:30am 8:45am Symposium #5: Breakfast 9:00am 12:00pm Session 7A: Adult Clinical Moderators: Imran Ahmad, MD, John Kuruvilla, MD 9:00am: How can we improve outcomes of patients with relapsed/refractory DLBCL in the Rituximab era Craig Moskowitz, MD 9:55am 10:10am Health Break located in the Atlantic Ballroom (see below) 10:10am: Title TBD Michael Crump, MD 11:05am: Consolidation and maintenance therapy after autologous transplant for multiple myeloma Philip L. McCarthy, MD Session 7B: Pediatric Clinical Maritime Room Moderators: Conrad Fernandez, MD, FRCPC, David Mitchell, MD, FRCPC 9:00am: Metabolic disorders in the age of expanding newborn programs Joanne Kurtzberg, MD 9:55am 10:10am Health Break located in the Atlantic Ballroom (see below) 10:10am: KIR typing Wing Leung, MD, PhD 11:05am: Assessment of MRD pre- and post-transplant in children with ALL Impact on transplant decision making Peter Bader, MD 9:55am 10:10am Health Break and Poster Group 4 Presentations Health break located in Atlantic Ballroom, Poster group presentations located in 12:00pm 2:00pm Symposium #6: Lunch CAG Educational Sessions 9:00am 5:00pm 5

Saturday, June 14, 2014 2:00pm 3:00pm 3:00pm 3:15pm 3:15pm 4:15pm 4:15pm 5:15pm Session 8: Hans Messner Lectureship Moderators: Stephen Couban, MD, Wanda Hasegawa, MD Primary refractory leukemia What to do next? Richard Larson, MD Health Break and Poster Group 5 Presentations Health break located in Atlantic Ballroom, Poster group presentations located in Session 9: Oral Abstract Presentations Lunenburg Room Moderators: Silvy Lachance, MD, FRCPC, CSPQ, Christopher Bredeson, MD Session 10: Fred Saunders Debate Moderators: Lynn Savoie, MD, Kylie Lepic, MD CAG Educational Sessions 9:00am 5:00pm Be it resolved that patients with acute lymphoblastic leukemia should have an allogeneic transplant in CR1 For the resolution: Daniel Weisdorf, MD Against the resolution: Matthew Seftel, MD, MPH, MRCP, FRCPC 5:15pm 5:45pm Closing Remarks 7:00pm Onwards Evening Social Waterfront Warehouse Sunday, June 15, 2014 8:00am 9:00am Symposium #7: Breakfast 9:00am 12:00pm CAG Sessions 6