4TH INTERNATIONAL PATIENT AND PHYSICIAN SUMMIT ON WALDENSTROM S MACROGLOBULINEMIA MARCH 10-13, 2011, ORLANDO, FL, USA

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1 4TH INTERNATIONAL PATIENT AND PHYSICIAN SUMMIT ON WALDENSTROM S MACROGLOBULINEMIA MARCH 10-13, 2011, ORLANDO, FL, USA Thursday, March 10, 2010 Buena Vista Palace Hotel 3:00 PM to 6:00 PM Registration (Hampton Court) 7:00 PM to 9:00 PM Faculty Dinner (Veranda Terrace) Friday, March 11, 2010 Buena Vista Palace Hotel 7:00 AM to 5:00 PM Registration (Hampton Court) 7:00 AM to 8:00 AM Breakfast (Ireland Room) 8:00 AM to 5:00 PM Summit Sessions (Scotland Room) Session I: Diagnosis of Waldenstrom s Macroglobulinemia Chair: Dr. Robert Kyle (US) 8:00 AM Dr. Roger Owen (UK) Pathological Diagnosis of WM 8:30 AM Dr. Marvin Stone (US) Clinical Features and Attributes of WM 9:00 AM Dr. Robert Kyle (US) Laboratory Workup of the Patient with WM 1

2 9:30-10:00 AM Refreshments 10:00 AM Dr. Fred Hochberg (US) Workup of the WM patient with Neuropathy 10:30 AM Dr. G. Merlini (ITALY) Workup of the WM patient with Amyloidosis 11:00 AM Dr. Irene Ghobrial (US) Prognostic Factors: How useful are they in WM? 11:30-12:00 PM Panel Discussion 12:00-1:30 PM LUNCHEON BREAK SPECIAL GUEST SPEAKER: Dr. Stephanie Gregory (US) New and Emerging Treatment Options for Indolent Lymphomas Session II: Predispositions to Waldenstrom s Macroglobulinemia Chair: Dr. Mary McMaster (US) 1:30 PM Dr. Robert Kyle (US) Is Monoclonal Gammopathy of Unknown Significance always a precursor to WM? 2:00 PM Dr. Ola Landgren (US) Epidemiological Studies in WM predisposition 2:30 PM Dr. Mary McMaster (US) Familial Predisposition in WM 3:00-3:30 PM Refreshments 3:30 PM Dr. Zachary Hunter (US) Revelations of SNP studies in WM familial predisposition 4:00 PM Dr. Enrica Morra (ITALY) Associated Malignancies in WM patients 2

3 4:30-5:00 PM Panel Discussion 5:00 PM Wrap Up and Adjournment 7:00-9:00 PM WELCOME RECEPTION AND DINNER at the Spectacular TWENTY SEVEN SKYWALK with panoramic views of Walt Disney World* *For Summit Attendees with Evening Event Pass. Please support the Summit by purchasing an Evening Event Pass. Evening Event passes can be purchased online at 3

4 Saturday, March 12, 2010 Buena Vista Palace Hotel 7:00 AM to 5:00 PM Registration (Hampton Court) 7:00 AM to 8:00 AM Breakfast (Ireland Room) 8:00 AM to 5:30 PM Summit Sessions (Scotland Room) Session III: Genetic Insights and Therapeutic Targets in WM Chair: Dr. Owen O Connor (US) 8:00 AM Dr. Zachary Hunter (US) Gene Expression and MicroRNA Profiling reveals distinct subsets of WM patients 8:30 AM Dr. Owen O Connor (US) Epigenetic Dysregulation in NHL 9:00-9:30 AM Refreshments 9:30 AM Dr. Irene Ghobrial (US) MTOR Pathway Dysregulation in WM and Novel Treatments 10:00 AM Dr. Steve Treon (US) B-cell Receptor Dysregulation in WM and Novel Treatments 10:30-11:00 AM Panel Discussion Session IV: Treatment of WM: Indications and Response Assessment Chair: Dr. Roger Owen (UK) 11:00 AM Dr. Robert Kyle (US) Indications for Treatment in WM 11:30 AM Dr. Roger Owen (UK) Response Assessment and Challenges 4

5 12:00-1:30 PM LUNCHEON BREAK SPECIAL GUEST SPEAKER: Dr. Matthias Rummel (GERMANY) Bendamustine: A new option for treatment of WM Session V: Treatment Strategies in WM Chair: Dr. Matthias Rummel (GERMANY) 1:30 PM Dr. Steve Treon (US) Frontline Treatment Strategies in WM including Novel Agents 2:00 PM Dr. Irene Ghobrial (US) Salvage Treatment Options in WM including Novel Agents 2:30 PM MS. Thea Ioakimidis (US) Maintenance Rituximab in WM 3:00-3:30 PM Refreshments 3:30 PM NP. Patricia Sheehy (US) Peripheral Neuropathy in WM 4:00 PM Dr. Fred Hochberg (US) Treatment of Neurological Complications in WM 4:30 PM Dr. H. Kyriakou (UK) Autologous and Allogeneic Transplantation in WM 5:00-5:30 PM Panel Discussion 5:30 PM Wrap Up and Adjournment 5

6 7:00-9:00 PM POOLSIDE DINNER GALA EVENT *For Summit Attendees with Evening Event Pass. Please support the Summit by purchasing an Evening Event Pass. Evening Event passes can be purchased online at 6

7 Sunday, March 13, 2010 Buena Vista Palace Hotel 8:00 AM to 1:00 PM Registration (Hampton Court) 8:00 AM to 9:00 AM Breakfast (Ireland Room) 9:00 AM to 1:00 PM Summit Sessions (Scotland Room) Session VI: Treatment Challenges in WM Chair: Dr. Nikhil Munshi (US) 9:00 AM Challenges in the Management of the WM Patient Dr. Munshi (US) 9:10 AM Debate: Is there a role for nucleoside analogue therapy in WM? YES- Dr. Morra (ITALY) NO- Dr. Merlini (ITALY) 9:40 AM Debate: Should Bendamustine-Rituximab be considered the standard frontline therapy in WM? YES- Dr. Rummel (GERMANY) NO- Dr. Gregory (US) 10:10 AM Debate: Should Bortezomib be considered a frontline option in WM patients? YES- Dr. Treon (US) NO- Dr. Owen (UK) 10:40 AM Debate: Should maintenance rituximab be used for rituximab responders in WM? YES- Dr Treon (US) NO- Dr. Kyle (US) 11:10 AM Debate: Should ASCT be a frontline option for WM? YES- Dr. Kyriakou (UK) NO- Dr. Stone (US) 7

8 11:40-12:00 PM Session Break Session VII: Case Presentations in WM Chair: Dr. Marvin Stone (US) 12:00 PM-1:00 PM 1:00 PM Dr. Treon Summit Summary and Adjournment. 8

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