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Curriculum Vitae Europass PERSONAL INFORMATION Name Work Address Scorsetti Marta SCRMRT67A57G558T Radiotherapy and Radiosugery Department, Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano (MI), Italy Telephone +39 0282248524 Mobile +39 3398630763 Fax +39 0282248509 E-mail marta.scorsetti@hunimed.eu Web Nationality www.hunimed.eu; www.humanitas.it Italian Date of birth January, 17th, 1967 Gender Female SCRMRT67A57G558T WORK EXPERIENCE March, 1st, 2016 now Humanitas University, Rozzano - Milan, Italy Associate Professor in Diagnostic Imaging and Radiotherapy Department of Biomedical Sciences Humanitas University September, 1st, 2003 now Humanitas Research Hospital, Rozzano - Milan, Italy Director, Department Managing projects and activities related to radiotherapy and radiosurgery development within the Hospital, leading clinical researches, managing collaborations with other hospitals and institutions. Leading collaborative, innovative research studies of original and high impact and author of a substantial number of manuscripts. Leading teaching activities for International postgraduate students, residents and young researchers in innovative techniques in radiation oncology. Member of regional/national committees developing guidelines, policies and Page 1 / 7 - Curriculum vitae of

protocols in programs for clinical care and quality assurance in Radiation Oncology. Member of the Board of Directors of Humanitas Cancer Center. Coordinator of the multidisciplinary teams within Humanitas Cancer Center. October 2001 July 2003 Associate Chief in Radiation Oncology Leading research in development of innovative models for high quality care in cranial and extracranial radiosurgical treatments exploiting the ultimate technologies. Collaboration in clinical studies and researches. January 1999 September 2001 Radiation Oncologist in charge of Radiosurgery programs Cranial and extra-cranial radiotherapy and radiosurgery in primary and metastatic brain tumors and lung cancers, collaborating in clinical researches. November 1994 November 1998 Resident in Radiation Oncology and Radiology Execution and reporting of Radiotherapy procedures under the supervision of the Chairmen, collaborating in clinical researches December 1994 January 1996 Assistant Radiation Oncologist Cranial and extra-cranial radiosurgery and 3D-radiotherapy in primary and metastatic brain tumor; collaborating in clinical researches. November 1991 October1993 Attendant Medical Doctor Cranial radiosurgery and 3D RadiationTherapy. EDUCATION AND TRAINING Name and type of organization providing education and training Page 2 / 7 - Curriculum vitae of November 1994- November 1998, Faculty of Medicine and Surgery School of Radiology and Radiotherapy. Department of Radiation Oncology at National Cancer Institute of Milan.

Principal subjects/occupational skills covered Title of qualification awarded Radiotherapy and Radiosurgery. Studies: radiobiology and physics, new approaches in radiotherapy treatment planning, integrated treatments (radio-chemotherapy in solid tumors), implementation of highly conformal radiation therapy techniques, as Radiosurgery and SBRT. November 5th, 1998: Post-graduate degree in Radiology and Radiation Oncology. Name and type of organization providing education and training Principal subjects/occupational skills covered Title of qualification awarded CLINICAL ACTIVITIES 1987-1993, Faculty of Medicine and Surgery,. School of Medicine and Surgery. Thesis: The role of Radiosurgery in the treatment of brain metastasis. October 15th, 1993: Degree in Medicine and Surgery. 1995-1997. Study and realization of a micro-dmlc s prototype (Dynamic Multileaf Collimator) now sold all around the world (3D-line, Elekta). 1997-1998. Leading researcher for one of the first Italian Linac-based Radiosurgery center in collaboration with C. Besta National Neurology Institute. 1994-1998. Implementation of new radiotherapy techniques, such as frameless radiosurgery, for cranial and extra-cranial tumors. 2003:Implementation of IMRT (Intensity Modulated Radiation Therapy) and SBRT (Stereotactic Body Radiation Therapy) for lung and abdominal cancers. 2005. First Italian Department of Radiation Oncology to develop planning tools for 4D Image Guided Adaptive Radiation Therapy and multimodality imaging simulation procedures (PET/MRI). 2005-2006: Principal coordinator of Clinical Risk Management project, in collaboration with IRER (Regional Institute of Research in Lombardia), for Quality Assurance programs in oncology. November 2008. Among the first centers in Europe and first Italian Center adopting volumetric modulated arc therapy (VMAT) using RapidArc technology. Implementation of hypofractionated treatments, especially for lung, liver and abdominal tumor. November 2010. First European Center introducing TrueBeam technology using Flattening Filter Free (FFF) modality for SBRT in lung, liver and prostate cancer. September 2012. Implementation of a radiosurgery program by the installation of BrainLab ExacTrack system for brain tumors with six-degrees of freedom coach on TrueBeam_STX. March 2014. Improvement of accuracy in target localization and management of intra-fraction organ motion: second installation in the world and first in Italy of the high precision EDGE linear accelerator with Calypso and OSMS tracking systems for frameless radiosurgery. TEACHING EXPERIENCE 2001-now Faculty of Medicine and Surgery Post-graduate School of Radiotherapy Adjunct professor of Radiation Oncology Teaching and tutoring for residents in Radiotherapy Page 3 / 7 - Curriculum vitae of

EDUCATIONAL ACTIVITIES Page 4 / 7 - Curriculum vitae of 2012-now International Medical School at Humanitas in collaboration with University of Milan Faculty of Medicine and Surgery Adjunct professor in Radiation Oncology Teaching and tutoring Diagnostic Imaging and Radiotherapy for medical students 2003-now Faculty of Medicine and Surgery Post-graduate Schools of Medical Oncology, Thoracic Surgery and General Surgery Lecturer in Radiation Oncology Lectures by invitation on different topics regarding the role of radiation therapy in treating cancers. 2003-now School for Radiotherapists (TSRM) Lecturer in Radiotherapy Lessons and training in advanced techniques in radiotherapy and radiosurgery 2003-now School of Nursing Lecturer in Radiotherapy Lessons and training in supportive care and management of chemo-radiation side effects 2003-2012 Faculty of Medicine and Surgery (H. San Paolo-Humanitas) Adjunct professor in Radiation Oncology Teaching and tutoring Diagnostic Imaging and Radiotherapy for medical students 2002-2005 o-bicocca Faculty of Medicine and Surgery Post-graduate School of Radiotherapy Adjunct professor in Radiation Oncology Teaching and tutoring Radiotherapy for residents. Coordinator of national and international professionals for training courses on current advanced techniques in radiotherapy, such as VMAT and SBRT. Coordinator of national and international professionals for familiarization in the use of current advanced techniques in collaboration with International Organizations (IAEA). Tutor of post-graduate residents in Radiotherapy, Oncology, Medical Physics and of radiotherapists in training. Supervisor of degree thesis of students of Medicine and Surgery, Nursing

School, post-graduate residents in Radiotherapy, Oncology, Medical Physics, biomedical engineers and radiotherapists in training. Lecturer at international symposia organized by The Institute for Medical Education-UCLA in Miami and New York (2011-2015). OTHER QUALIFICATIONS ACTIVITIES 2015: Italian National Scientific Qualification as Full Professor in Diagnostic Imaging and Radiotherapy (sector 06/I1) 2015: Italian National Scientific Qualification as Associate Professor in Diagnostic Imaging and Radiotherapy (sector 06/I1) Italian LANGUAGES MOTHER TONGUE OTHER LANGUAGES Reading skills Writing skills Verbal skills English Excellent Excellent Excellent French Good Good Good Reading skills Writing skills Verbal skills SCIENTIFIC SOCIETIES Coordination Roles: 2013-now: Member of Ethical Committee of National Cancer Institute of Milan. 2009-2012: Member of Board of Directors of FONICAP (Interdisciplinary National Operative Force Against Lung Cancer. 2011-2014: Member of Board of Directors of AIRO (Italian Association of Radiation Oncology). 2010-2012: Coordinator of AIRO lung cancer work group. 2008-2010: Coordinator of AIRO SBRT work group. Collaborator with national study groups of AIRO (Italian Association of Radiation Oncology), AIOM (Italian Association of Medical Oncology) and ISS (Superior Institute of Health)). Membership: Italian Association of Radiotherapy (AIRO) European Society for Radiotherapy & Oncology (ESTRO) Interdisciplinary National Operative Force Against Lung Cancer (FONICAP) International Association for the Study of Lung Cancer (IALSC) RESEARCH ACTIVITIES Principal Investigator in the following ongoing studies (www.clinicaltrials.gov): Randomized study on postmenopausal women with early stage breast Page 5 / 7 - Curriculum vitae of

cancer: adjuvant Hypofractionated Whole Breast Irradiation (WBI) versus Accelerated Partial Breast Irradiation (APBI) (ID: NCT02375048). A randomised phase III trial on stereotactic body radiation therapy (SBRT) after incomplete transcatheter arterial embolization (TAE) or transcatheter arterial chemoembolization (TACE) versus exclusive TAE or TACE for treatment of hepatocellular carcinoma (HCC) (ID: NCT02323360). Comparative evaluation of two different radiosurgery modalities in brain metastatic patients from several solid tumors (ID: NCT02355613). Hypofractionated IMRT (VMAT-RA) with temozolomide for patients with newly diagnosed high grade glioma (HGG) (ID: NCT02082119). Hypofractionated IMRT (VMAT-RA) with temozolomide for elderly patients, unsuitable for surgery, with newly diagnosed high grade glioma (HGG) (ID: NCT02099487). Phase II Study on SBRT for treatment of uresectable lung oligometasases in patients with soft tissues sarcoma (ID: NCT02561559). Phase I-II Study of high dose SBRT in 4 fractions for intermediate risk prostate cancer Tumor bed hypofractionated IMRT (VMAT-RA) after surgical for patients with single, large ( 2.1 cm) brain metastasis from solid tumor. REVIEW ACTIVITIES Guest editor: Reports of Practical Oncology and Radiotherapy: Special Issue on Stereotactic Body Radiation Therapy: An attractive weapon in anticancer treatment DOI: http://dx.doi.org/10.1016/j.rpor.2015.07.001. Reviewer: International Journal Of Radiation Oncology, Biology, Physics Radiotherapy and Oncology Radiation Oncology Tumori Journal Medical Physics Acta Oncologica Strahlenther Onkologie Reports of Practical Oncology and Radiotherapy Lung Cancer Journal of Cancer Research and Clinical Oncology GRANTS Varian: Comparative evaluation of two different radiosurgery modalities for SCIENTIFIC ACTIVITY brain metastasis. Varian Phase I-II study of high dose SBRT in 5 fractions for low-intermediate risk prostate cancer. Pub Med Hits: 119 Scopus Hits: 126 Page 6 / 7 - Curriculum vitae of

H-index = 21 (Scopus) H-index last 5 years = 19 (Scopus 2011-2016) AWARDS Total Impact Factor = 357.767 (Scopus) Total Impact Factor last 5 years = 369.997 Chapters of books: 3 Abstract presented at meetings = more than 100 Invited speaker, moderator, organizer at more than 100 meetings 2006 Banfi Award for treatment of liver metastases using Stereotactic Body Radiation Therapy 2013 Varian Center of Excellence Award Milan, February 17 Marta Scorsetti La sottoscritta è a conoscenza che, ai dell art.26 della Legge 15/68, le dichiarazioni mendaci, la falsità negli atti e l uso di atti falsi sono puniti ai sensi del codice penale e delle leggi speciali. Inoltre, il sottoscritto autorizza al trattamento dei dati personali, secondo quanto previsto dal D. lgs. 196/03. Page 7 / 7 - Curriculum vitae of