CURRICULUM VITAE ALBENA HALPERT, M.D.

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ALBENA HALPERT, M.D. DATE: May 26, 2010 PERSONAL INFORMATION: SEX: F DATE OF BIRTH: September 28, 1965 PLACE OF BIRTH: CITIZENSHIP: Varna, Bulgaria American Citizen ADDRESS AND TELEPHONE NUMBERS: OFFICE: Boston University School of Medicine 85 East Concord Suite 7700A Boston, MA 02118 (617) 638 6525 HOME: 9 Munroe Street Newton, MA 02460 (617) 272 0004 PRESENT POSITION: 2004-present ( part time) 2007-present ( part time) Assistant Professor in Medicine Section of Gastroenterology, Boston University School of Medicine, Boston MA Gastroenterologist Pentucket Medical Associates, Haverhill, MA EDUCATION: 1979-1983 Gymnazium Peter Beroun Varna, Bulgaria 1984-1990 Charles University School of Medicine Prague, Czechoslovakia Doctor of Medicine

Page 2 POST-DOCTORAL TRAINING 6/90-10/92 Clinical Attachment, General Medicine, Walsgrave Hospital, Coventry, UK. Preparing for the Professional and Linguistic Ability (PLAB) exam 10/92-2/93 House Officer in Surgery Banbury, UK 2/93-8/93 House Officer in Internal Medicine Hemel Hempstead, UK 8/93-2/94 House Officer in Surgery King Edward VII, Hospital, Midhurst, UK 2/95-6/95 Research Associate, Department of Anesthesiology St. Louis University Health Sciences Center, St. Louis, MO 63110 7/95-6/98 Resident, Department of Internal Medicine St. Louis University Health Sciences Center, St. Louis, MO 63110 7/99-6/2002 Fellow, Gastroenterology and Hepatology St. Louis University Health Sciences Center, St. Louis, MO 63110 7/2002-7/2004 Research Fellow /Clinical Instructor UNC Center for Functional GI and Motility Disorders Department Of Medicine /Digestive Diseases Chapel Hill, NC 27599 HOSPITAL APPOINTMENTS 7/98-7/99 Critical Care Physician, Christian North East Hospital St. Louis, MO 63110 MEDICAL LICENSURE AND BOARD CERTIFICATION: Medical License Massachusetts (# 222390) Board Certification in Internal Medicine 1998 Board Certification in Gastroenterology 2002 USMLE (#4985784) PROFESSIONAL SOCIETIES: 1999-Present 1999-Present 2000-Present 2003-Present 2006-Present American Gastroenterology Association American College of Gastroenterology International Foundation for Functional Gastrointestinal Disorders American Academy of Physicians and Patients Digestive Center for Women Network

Page 3 EDITORIAL BOARDS 2004-Present ad hoc reviewer Gastroenterology 2004-Present ad hoc reviewer J. of Clinical Gastroenterology &Hepatology 2007-Present ad hoc reviewer Patient Education and Counseling 2007-Present ad hoc reviewer Psychosomatic Medicine OTHER PROFESSIONAL POSITIONS 2006-present Chloride Channel Council Takeda Pharmaceuticals 2006-present Consultant Procter & Gamble BIBLIOGRAPHY: Manuscripts and Book Chapters: 1. Halpert A. Patient Education: A Paradigm Shift. UNC Functional GI disorders and Motility Center Digest 2003; 4:19-20. 2. Halpert A. Does Desipramine Dose Matter in the Treatment of Functional Bowel Disorders? UNC Functional GI Disorders and Motility Center Digest 2004; 4:9-12. 3. Halpert A, Drossman D. Chapter Evidence Based Medicine BMJ: Irritable Bowel Syndrome: Diagnosis and Treatment. BMJ Books, London, UK, pp. 265-283, 2004. 4. Halpert A, Drossman D. Gender and Irritable Bowel Syndrome: The Male Connection. J Clin Gastro 2004; 38:546-548. 5. Halpert A, Dalton CB, Diamant NE, Toner BB, Hu Y, Morris CB, Bangdiwala SI, Whitehead WE, Drossman DA. Clinical response to tricyclic antidepressants in functional bowel disorders is not related to dosage. Am J Gastroenterol 2005; 100:664-71. 6. Halpert A, Drossman. Biopsychosocial Issues in Irritable Bowel Syndrome. Journal of Clinical Gastroenterology 2005; 39:665-669. 7. Halpert A, Thomas A., Hu Y, Morris C, Bangdiwala, S, Drossman D. A Survey on Patient Educational Needs in Irritable Bowel Syndrome and Attitudes Toward Participation in Clinical Research. Journal of Clinical Gastroenterology 2006; 40(1): 37-43. 8. Halpert, A. What Patients Know About Irritable Bowel Syndrome (IBS) and What They Would Like to Know. Digestive Health Matters 2007; 16(1):3-4. 9. Halpert A, Dalton C, Palsson O, Morris C, Hu Y, Bangdiwala S, Hankins J, Norton N, Drossman D. What Patients Know About Irritable Bowel Syndrome (IBS) and What They Would Like to Know. National Survey on Patient Educational Needs in IBS and Development and Validation of the Patient Educational Needs Questionnaire (PEQ). Am J Gastroenterol 2007; 102:1972-1982. 10. Di Palma J, Halpert A, (Medical Consultants). Guidelines- Pocket Card, Managing Chronic Constipation, ACG Institute and International Guidelines Center, 2008. 11.Halpert A, Dalton C, Palsson O, Morris C, Hu Y, Bangdiwala S, Hankins J, Norton N, Drossman D. Patient Educational Media Preferences for Information about Irritable Bowel Syndrome (IBS) Digestive Diseases and Sciences, 2008 53:3184 3190

Page 4 12. Halpert, A, Groesbeck, M. Strengthening the Patient-Clinician Relationship: Management of IBS in Primary Care. Duke University School of Medicine in association with DIME, IBSCME.org Web site. 2009. Available at: http://www.ibscme.org/ 13. Halpert A, Dalton C, Palsson O, Morris C, Hu Y, Bangdiwala S, Hankins J, Norton N, Drossman D. Irritable Bowel Syndrome Patients' Ideal Expectations and Recent Experiences with Health Care Providers: A National Survey. Digestive Diseases and Sciences: Volume 55, Issue 2 (2010), Page 375. 14. Halpert A. Irritable Bowel Syndrome: Getting from better to well. Gastroenterology & Endoscopy News. December, 2009. 15. Halpert A, Importance of Early Diagnosis in Irritable Bowel Syndrome, Journal of Postgraduate Medicine. March, 2010. Volume 122: No. 2 16. Halpert, A, Rybin, D, Doros, G. Expressive Writing is a Promising Therapeutic Modality for the Management of IBS. Digestive Diseases and Sciences. April, 2010. 17. Halpert, A, Rybin, D, Doros, G. Expressive Writing is a Promising Therapeutic Modality for the Management of IBS A Pilot Study. American Journal of Gastroenterology. advance online publication 15 June 2010. Selected Abstracts/Poster Presentations: 1. Halpert A, Prather C. Endoanal Ultrasound and Anorectal Manometry Are Complementary Tools When Evaluating Patients with Fecal Incontinence. American Journal of Gastroenterology 2001; 96(9): S151. 2. Halpert A, Drossman D, et al. Is Clinical Response to Tricyclic Antidepressants Related to Dosage? American Journal of Gastroenterology 2005; 100(3): 664-71. 3. Halpert A, Drossman D, et al. A survey on patient educational needs in irritable bowel syndrome and attitudes toward participation in clinical research. Poster presentation, APS meeting Orlando Fl, March 2004. 4. Halpert A, Drossman D, et al. The Relationship Between Illness Related Attitudes and Beliefs and Clinical Outcome in Functional Bowel Disorders (FBD). Gastroenterology 2004; 126(4): T1362. 5. Halpert A, Drossman D, et al. Factors Predicting Illness Related Attitudes and Beliefs: Validation of the GI-IMIQ in Functional Bowel Disorders (FBD). Gastroenterology 2004; 126(4): T1363. 6. Halpert, A, Whitehead W, et al. Rectal Contractions are Part of Normal Defecation. Gastroenterology 2004; 126(4): M1582. 7. Dalton C, Halpert A, Drossman D, et al. Are Side Effects of Tricyclic Antidepressants (TCAs) Really Side Effects? Gastroenterology 2004; 126(4): 250. 8. Halpert A, Drossman D. Does Patient Education Improve Clinical Outcomes in IBS? Gastroenterology 2005; 128: M1248. 9. Halpert A, Dalton C, Paulson O, Hu Y, Morris C, Drossman D. National Survey on Patient Education in Irritable Bowel Syndrome (IBS). Am J Gastro 2005;100:S336.

Page 5 10. Halpert A, Drossman D, et al. What Patients with Irritable Bowel Syndrome (IBS) expect from their health care providers. National Survey on IBS Educational Needs and Expectations. Gastro 2006; 130: A505. 11. Halpert A, Drossman D, et al. The Use of Patients Narratives in Irritable Bowel Syndrome (IBS). Am J Gastroenterol. 2006; 101: S476. 12. Halpert A, Clark J, et al. Patients Expressive Writing about their Irritable Bowel Syndrome is Informative, but Difficult to Read Reliably for the Theme Understanding patient perspective. Poster Presentation. AACH International Conference on Communication in Healthcare, Charlestown, SC, October 2007. 13. Halpert A, Drossman D, et al. Pilot Study on Patient Centered Educational Intervention in Irritable Bowel Syndrome (IBS). Poster Presentation. AACH International Conference on Communication in Healthcare, Charlestown, SC, October 2007. 14. Halpert A, Clark J, et al. Patients Expressive Writing about their Irritable Bowel Syndrome is Informative, but Difficult to Read Reliably. Poster Presentation. American College of Gastroenterology (ACG) 2008 Poster Session, Orlando, FL, October 2008. 15. Halpert A, Verma A. Expressive Writing as a Therapeutic Modality in Irritable Bowel Syndrome (IBS). Poster Presentation. American College of Gastroenterology (ACG) 2008 Poster Session, Orlando, FL, October 2008. 16. Expressive Writing is a Promising Therapeutic Modality for Irritable Bowel Syndrome (IBS), Oral Presentation, DDW Meeting, Chicago, Il, May 2009. 17. Understanding Irritable Bowel Syndrome (IBS) Through Patients Expressive Writings, Poster Presentation, DDW Meeting, Chicago, Il, May 2009. 18. Physicians' Attitudes Towards the Use of Patients' Expressive Writings about Irritable Bowel Syndrome in the Outpatient Setting poster presentation, DDW Meeting, Chicago, Il, May 2009. 19. Patient-Centered Educational Intervention in Irritable Bowel Syndrome (IBS), Oral Presentation, DDW Meeting, New Orleans, LA, May 2010. 20. Attitudes Regarding the Use of Patients Writings about IBS in the Outpatient Setting among Physicians, Medical Students, and Patients, Oral Presentation, DDW Meeting, New Orleans, LA, May 2010. Multimedia: Videotape. Drossman DA., Halpert, A. Psychosocial Soundbites Medical Sciences Teaching Laboratories, University of North Carolina School of Medicine, Chapel Hill, N.C., June 2003. Television interview: Management of Irritable Bowel Syndrome Segment. PBS Healthy Mind, Healthy Body Program, August, 2007. GRANTS AND AWARDS: On going 1. Investigator Initiated Award 09/01/08-Present Takeda Pharmaceutical North America The Use of Expressive Writing in the Management of Irritable Bowel Syndrome Specific Aim: To test the effectiveness of writing about disease related emotional experiences on IBS-

specific quality of life (IBS QOL) and change in health cognition (CT3 catastrophizing/coping) CURRICULUM VITAE Page 6 Recent awards 1. American College Gastroenterology. 07/01/06-06/30/08 ACG 2006 Junior Faculty Development Award The Impact of Patient Education on Clinical Outcomes in Irritable Bowel Syndrome. Specific Aims: To test the effectiveness of a brief, individualized, theory-based, educational intervention on IBS outcomes. The primary outcome assesment measure will be change of IBS specific quality of life. Secondary outcome measures will include satisfaction with care, change in health cognition (IBS), cognitive scale, catastrophizing or maladaptive coping, ability to control symptoms, ability to decrease symptoms), and health care utilization. 2. 2004 GIDH Healthcare Advancement Award. 07/01/04-07/01/07 GlaxoSmithKline. Survey on Patient Education in IBS Development and Validation of the IBS Patient Educational Questionnaire (IBS PEQ)- part II Specific Aims: To identify the content and process by which effective patient education on IBS can be provided. More specifically to identify what perceptions patients with IBS hold about their condition, the content areas in which patients with IBS feel insufficiently informed, the types of educational media patients with IBS prefer, and what patients expect from the health care education providers. 3. Unrestricted Educational Award. Forest Laboratory 04/20/03-04/20/05 Survey on Patient Education in IBS. Development and Validation of the IBS Patient Educational Questionnaire (IBS PEQ) part I Specific Aims: This study identified the content and process by which effective patient education on IBS can be provided. 4. American College Gastroenterology. 07/01/02-06/30/04 2002 ACG Clinical Investigator Research Award, $35,000 Does Education Improve Outcome in Patients with Irritable Bowel Syndrome? Specific Aims: To develop the Patient Education Needs Questionnaire (PEQ), address the patient s knowledge, perceptions, and needs relating to education about IBS. Additionally, the study compared the efficacy of pre-clinic patient education to a clinic visit alone in patients with IBS. SELECTED INVITED PRESENTATIONS: 1. Why doctors need to prescribe information Novartis pharmaceuticals preceptorship symposium on irritable bowel syndrome, Chapel Hill NC - 2/26/03. 2. Patient education in IBS Functional GI group research club, Mayo Clinic, Rochester, MN -1/26/04. 3. Diarrhea Patient symposium on irritable bowel syndrome, Chapel Hill NC 6/14/2004. 4. What patients with IBS know and what do they need to know, International Foundation for Functional Bowel Disorders meeting, Milwaukee, WI - 4/7/05. 5. Patient education University of North Carolina center for functional bowel disorders research day Chapel Hill NC - 6/11/05 6. Advances in the treatment of irritable bowel syndrome, Novartis pharmaceutical representatives preceptorship, Boston, MA- 8/3/05 7. Non-pharmacological approaches in the management of irritable bowel syndrome, ground rounds

Massachusetts General Hospital, Harvard University, Boston, MA - 10/11/05 CURRICULUM VITAE Page 7 8. Advances in the management of functional bowel disorders, Boston Women s Forum, Boston, MA 10/6/06 9. Advances in the management of chronic constipation and IBS with chronic constipation Internal medicine ground rounds, St. Joseph Hospital, Nashua, NH 10/18/06 10. Role of patient education in functional bowel disorders. Harvard motility post graduate course- 11/11/06 11. Management of irritable bowel syndrome, Takeda pharmaceuticals scientific regional meeting Boston, MA-11/29/06 12. Functional bowel disorders, small bowel bacterial overgrowth and gas, A Core Curriculum in Adult Primary Care Medicine, Boston 01/06/07 13. Chronic Constipation, Sucampo pharmaceuticals preceptorship symposium on Chronic Constipation, 01/24/07, Boston, MA 14. Patient Education Research: What do patients want to know, International Foundation for Functional Gastrointestinal Disorders Meeting, 04/12/07, Milwaukee, WI. 15. Interview Techniques and Communication Skills, International Foundation for Functional Gastrointestinal Disorders Meeting, 04/13/07, Milwaukee, WI. 16. Patient education in IBS: What do patients want to know?" Association of Gastrointestinal Motility Disorders (AGMD) Symposium, 07/27/07, Boston, MA. 17. New Treatments for Irritable Bowel Syndrome, Constipation & Fecal Incontinence, 22 nd Annual Smithwick Symposium, Boston University School of Medicine, 11/16/07, Boston, MA. 18. Challenges in GI Motility and Functional GI Diseases: A case based approach. 9 th Annual Boston Motility Meeting, Simches Conference Center, Massachusetts General Hospital,10/25/08, Boston, MA. 19. Maximizing the Physician Patient Relationship. International Foundation for Functional Gastrointestinal Disorders Meeting, 04/19/09, Milwaukee, WI. 20. Maximizing the Physician Patient Relationship. Association of Gastrointestinal Motility Symposium. 7/24/09. Bedford, MA 21. Management of Motility and Functional Bowel Disease. 10 th Annual Boston Motility Meeting, Simches Conference Center, Massachusetts General Hospital, 10/10/09, Boston, MA 22. Functional Bowel Disorders and the Physician Patient Relationship. Pediatric GI Grand Rounds, Floating Children s Hospital, New England Medical Center, 10/30/09, Boston, MA 23. Expressive Writing in IBS. BMC Center for Integrative Medicine meeting, 12/7/09. Boston Medical Center, Boston, MA 24. Celiac Disease Update. Lawrence General Hospital Internal Medicine Grand Rounds, 2/09/2010 Lawrence General Hospital, Lawrence, MA 25. Meet the Professor Luncheon: Interviewing the Difficult GI Patient. DDW Meeting, New Orleans, LA, May 2010.