ZURICH, SWITZERLAND, OCTOBER 5TH-7TH,

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HOT TOPICS in CARDIOLOGY ZURICH, SWITZERLAND, OCTOBER 5TH-7TH, 2017 Auditorium Careum and Hotel Marriott Zurich PROGRAMME

CHAIRMAN Prof. Thomas F. Lüscher Head of Cardiology, University Hospital Zurich PROMOTED BY Fondazione Internazionale Menarini Centro Direzionale Milanofiori Edificio L Strada 6 20089 Rozzano (Milan, Italy) Phone: +39 02 55308110 Fax: +39 02 55305739 E-mail: milan@fondazione-menarini.it www.fondazione-menarini.it SCIENTIFIC COORDINATION, ORGANISATION Dr. Ruth Amstein Zurich Heart House ORGANIZING SECRETARIAT MARBEN S.r.l. Via Melzi d'eril, 20-20154 Milano Tel. +39 02 3491732 Fax +39 02 3315750 www.marben.it 3

Welcome Address Dear Colleagues The University Hospital Zurich has a long tradition in pioneering research and developments in cardiovascular medicine. Indeed, in the sixties the renowned cardiac surgeon Ake Senning established one of the first cardiac surgery departments in Zurich. Besides the worldwide first implantation of a pacemaker, he developed new surgical techniques and procedures particularly for patients with congenital heart disease. Furthermore, in 1977 Andreas Grüntzig successfully performed in Zurich the first percutaneous coronary intervention with a balloon catheter he had developed. His seminal intervention has become one of the most frequently performed procedures in patients with coronary disease and opened the door for interventions in structural heart disease. The current department has continued this tradition and contributed substantially to the understanding and management of atherosclerotic vascular disease and heart failure. On the background of these historic milestones in cardiovascular medicine, it is our great pleasure to continue this tradition as a center of excellence in cardiovascular medicine and to invite you to the preceptorship programme on hot topics in cardiology in Zurich. The programme will focus on special areas with most recent therapeutic advances and innovations including risk factors and cardiovascular prevention, angina and acute coronary syndromes, atrial fibrillation, valve disease and heart failure. A distinguished international teaching faculty will contribute to an outstanding programme on the latest scientific and therapeutic developments in the respective areas. The educational objectives are to provide a comprehensive update on new diagnostic approaches, clinical trials and treatment modalities. State of the art lectures will be illustrated with demonstrations of patient cases, round table discussions and video live cases for interventional valve procedures. A particular emphasis will be placed on chronic and acute heart failure, the new epidemic of the 21st century. Cardiovascular clinicians, internists, and primary care physicians attending will derive benefit from this three-day preceptorship course with the goal to better serve their patients. We are looking forward to welcoming you in Zurich and spending a stimulating meeting together. Thomas F. Lüscher, MD, FRCP, FESC Professor and Chairman of Cardiology 4

Thursday, October 5 th, 2017 VENUE: AUDITORIUM CAREUM, UNIVERSITY CAMPUS CAREUM OPENING CEREMONY 16:30 Welcome Address Thomas F. Lüscher (Zurich, CH) 17:30 Welcome by the Rector of the University of Zurich Prof. Dr. Michael Hengartner 18:30 Opening Lecture 1 Joseph Wu (Stanford, US) Stem Cells and Genomics for Precision Medicine 19:30 Opening Lecture 2 Valentin Fuster (New York, US) Prevention or intervention? 20:30 Welcome Cocktail Friday, October 6 th, 2017 VENUE: HOTEL MARRIOTT, ZURICH SESSION I RISK FACTORS AND PREVENTION Chairpersons: Jürg Beer (Baden, CH) François Mach (Geneva, CH) 08:30 Massimo F. Piepoli (Piacenza, IT) What can we learn from the new ESC Guidelines on CVD prevention? 08:50 Isabella Sudano (Zurich, CH) An interesting patient with multiple risk factors 09:00 Giuseppe Mancia (Milan, IT) Hot topics in the management of hypertension 09:20 Alberico Catapano (Milan, IT) Hot topics in lipid management 09:40 Christoph Wanner (Wurzburg, DE) Improving diabetes outcomes: beyond glucose metabolism 10:00 Sanjay Sharma (London, UK) How can exercise training and diet influence risk management? 10:20 Discussion 10:30 11:00 Coffee Break 5

SESSION II ANGINA AND ACS Chairpersons: Filippo Crea (Rome, IT) Urs Eriksson (Wetzikon, CH) 11:00 Robert Manka (Zurich, CH) Stable CAD: diagnosis: from symptoms to imaging 11:20 Bernard Gersh (Rochester, US) Stable CAD: CABG versus PCI 11:40 Thomas F. Lüscher (Zurich, CH) Takotsubo, an often-unrecognized acute heart disease 12:00 Thomas F. Lüscher (Zurich, CH) DAPT therapy: how long for whom? 12:20 Stefan James (Uppsala, SE) Management of STEMI patients according to the ESC Guidelines 12:45 13:45 Lunch Buffet SESSION III - ATRIAL FIBRILLATION Chairpersons: Bernard Gersh (Rochester, US) Firat Duru (Zurich, CH) 13:45 A. John Camm (London, UK) Diagnosis and classification of AF 14:05 Alexander Breitenstein (Zurich, CH) An interesting patient with AF 14:15 José Francisco Kerr Saraiva (Sao Paulo, BR) Medical therapy of AF 14:35 Gerhard Hindricks (Leipzig, DE) Catheter ablation of AF 14:55 Renato Lopes (Durham, US) Stroke Prevention in patients with AF: What is new in 2017? 15:15 Discussion 15:30 16:00 Coffee break 6

SESSION IV - VALVE DISEASE Chairpersons: Tiziano Moccetti (Lugano, CH) Thomas F. Lüscher (Zurich, CH) 16:00 Bernard Prendergast (London, UK) TAVI: state of the art 16:20 An interesting patient with aortic stenosis (Case presentation: Erik Holy, Zurich live in-a-box: Thomas F. Lüscher, Zurich) 16:40 Felix C. Tanner (Zurich, CH) The role of imaging 17:00 Stephan Windecker (Berne, CH) Patient selection for TAVI 17:20 Francesco Maisano (Zurich, CH) Percutaneous mitral valve repair 17:40 Discussion 18:00 Adjourn Saturday, October 7 th, 2017 VENUE: HOTEL MARRIOTT, ZURICH SESSION V - CHRONIC HEART FAILURE Chairpersons: Roger Hullin (Lausanne, CH) Frank Ruschitzka (Zurich, CH) 08:30 Piotr Ponikowski (Wroclaw, PL) New HF ESC Guidelines definition and classification of HF 09:00 Andreas Flammer (Zurich, CH) An interesting patient with chronic HF 09:20 Thomas F. Lüscher (Zurich, CH) Pharmacological treatment of HF 10:00 Carolyn Lam (Singapore, SGP) HF with preserved systolic function 10:30 Theresa McDonagh (London, UK) Comorbidities in HF 11:00 Alexander Breitenstein (Zurich, CH) Devices and interventions 11:30 Discussion 7

SESSION VI - ACUTE AND ADVANCED HEART FAILURE Chairpersons: Piotr Ponikowski (Wroclaw, PL) Otmar Pfister (Basel, CH) 11:45 Mandeep R. Mehra (Boston, US) Causes and pathophysiological mechanisms of acute heart failure 12:15 Frank Enseleit (Zurich, CH) An interesting patient with acute HF 12:35 Marco Metra (Brescia, IT) Management of acute HF 13:05 Frank Ruschitzka (Zurich, CH) Advanced heart failure 13 35 Marisa Crespo-Leiro (La Coruna, ES) Heart transplantation 14:05 Ulf Landmesser (Berlin, DE) The future of stem cell therapy and cardiac regeneration 14:45 Discussion 14:45 Wrap-up and Close Thomas F. Lüscher 8

FACULTY Beer Jürg Hans Kantonsspital Baden Baden CH Breitenstein Alexander Camm A. John P St. George's Hospital Med. School London UK Catapano Alberico L. University of Milan Milan IT Crea Filippo Catholic University of the Sacred Heart Rome IT Crespo-Leiro Marisa University Hospital of La Coruna La Coruña ES Duru Firat Enseleit Frank Eriksson Urs Spital Wetzikon Wetzikon CH Flammer Andreas Fuster Valentin The Mount Sinai Hospital New York US Gersh Bernard J. Division of Cardiovascular Diseases Rochester US Hengartner Michael O. Universität Zürich Hindricks Gerhard Herzzentrum Leipzig GmBH Leipzig DE Holy Erik Walter Hullin Roger Centre Hospitalier Universitaire Vaudois Lausanne CH James Stefan K. Department of Medical Sciences Uppsala SE Kerr Saraiva José Francisco Pontifícia Universidade Católica de Campinas (PUC) Campinas, Sao Paulo BR Lam Su Ping Carolyn National University Heart Center, Singapore, SGP Landmesser Ulf Charité - Universitätsmedizin Berlin Berlin DE 9

Lopes Renato Delascio Duke University School of Medicine Durham US Lüscher Thomas F. Mach François Hôpitaux Universitaires Genéve (HUG) Genf CH Maisano Francesco Mancia Giuseppe Università di Milano Monza IT Manka Robert McDonagh Theresa A. King s College Hospital London UK Mehra Mandeep R. Brigham and Women's Hospital Boston US Metra Marco Brescia and Spedali Civili Brescia IT Moccetti Tiziano Cardiocentro Ticino Lugano CH Piepoli Massimo F. Guglielmo da Saliceto Hospital Piacenza IT Ponikowski Piotr Clinical Military Hospital Wroclaw PL Prendergast Bernard London Bridge Hospital London UK Ruschitzka Frank Sharma Sanjay St George's Healthcare NHS Trust London UK Sudano Isabella Tanner Felix C. Wanner Christoph Universität Würzburg Wurzburg DE Windecker Stephan Inselspital, Universitäts Spital Bern Bern CH Wu Joseph C. Stanford Cardiovascular Institute Stanford CH 10 Pfister Otmar Universitätsspital Basel Basel CH

GENERAL INFORMATION Meeting venue October 5 th, 2017 Auditorium Careum, University Campus Careum, Zurich October 6 th 7 th, 2017 Hotel Marriott Zurich Official language English. Simultaneous translation will be provided for the following languages: French, German and Italian. Registrations http://www.marben.it/hot-topics-in-cardiology/ No registration fee is required to attend the Conference. The Secretariat will be open at the following times: Thursday, October 5 th : 03.30 p.m. to 06.00 p.m. Friday, October 6 th : 07.00 a.m. to 06.00 p.m. Saturday, October 7 th : 07.00 a.m. to 01.00 p.m. Congress website www.zhh.ch/en/events/hot-topics-cardiology CME Accreditation The application for CME accreditation has been submitted for Italian Physicians. The CME credits will be awarded only after full attendance of all sessions. Completion of the Registration Form, the Learning & Assessment questionnaires are compulsory. Swiss Accreditation Swiss Society of Cardiology: 13 CME credits category 1A Swiss Society of General Internal Medicine: 13 CME credits category 1A 11

GENERAL INFORMATION European Accreditation An application has been submitted to the EACCME for CME accreditation of this event. Lunches and coffee breaks Lunches and coffee breaks will be served in the Meeting area. Abstracts book Participants will receive the Abstract book at the Meeting. Attendance certificate The attendance certificate will be issued at the accreditation desk following full attendance at the Conference. SPEAKER'S INFORMATION Technical facilities A Slide Center with PCs (Windows and Macintosh operating systems) will be available for Speakers to preview and finalize their presentations. Speakers are kindly requested to submit their presentations on USB flash drive to the Slide Center technicians at least one hour before their talks. Slide Centre opening hours Thursday, October 5 th : 03.30 p.m. to 06.00 p.m. Friday, October 6 th : 07.00 a.m. to 06.00 p.m. Saturday, October 7 th : 07.00 a.m. to 01.00 p.m. 12

NOTE 13

NOTE 14

Fondazione Internazionale Menarini Symposia n. 352 REGISTER NOW http://www.marben.it/hot-topics-in-cardiology For more information and registration please visit: www.fondazione-menarini.it