Biology 12. Examination Booklet August 2007 Form A DO NOT OPEN ANY EXAMINATION MATERIALS UNTIL INSTRUCTED TO DO SO.

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Biology 12 Examination Booklet August 2007 Form A D NT PEN ANY EAMINATIN MATERIALS UNTIL INSTRUCTED T D S. FR FURTHER INSTRUCTINS REFER T THE RESPNSE BKLET. Contents: 28 pages Examination: 2 hours 67 multiple-choice questions in the Examination Booklet Additional Time Permitted: 60 minutes Province of British Columbia

PART A: MULTIPLE CHICE Value: 67 marks Suggested Time: 80 minutes INSTRUCTINS: For each question select the best answer and record your choice on the Answer Sheet provided. Using an HB pencil, completely fill in the bubble on the Answer Sheet that has the letter corresponding to your answer. You have Examination Booklet Form A. In the box above #1 on your Answer Sheet, fill in the bubble as follows. Exam Booklet Form/ Cahier d examen A B C D E F G H 1. Which of the following are found in lysosomes? A. ATP B. RNA C. enzymes D. glycogen 2. What organelle functions with the endoplasmic reticulum during protein production? A. the ribosome B. the lysosome C. the chloroplast D. the cell membrane Biology 12 0708 Form A Page 1

Use the following diagram to answer question 3. Y Z W 3. Where are drugs detoxified in liver cells? A. W B. C. Y D. Z Use the following diagram to answer question 4. Z Y W 4. Which organelle contains the information necessary to produce enzymes? A. W B. C. Y D. Z Page 2 Biology 12 0708 Form A

5. Which of the following molecules, when added to water, will produce a solution with the lowest ph? A. cellulose B. neutral fat C. nucleic acid D. monosaccharide Use the following graph to answer question 6. ph 8 7 6 5 4 3 T Time W Y Z 6. At time T, a small amount of dilute acid is added to a solution buffered to ph 5.0. Which line on the graph illustrates the change in ph of the solution following the addition of the weak acid? A. W B. C. Y D. Z 7. Which of the following equations illustrates a synthesis reaction? A. acid + base salt + water B. ATP ADP + P + energy C. protein+ water amino acids D. glucose + glucose maltose + water Biology 12 0708 Form A Page 3

8. Which of the following molecules insulates the body from heat loss? A. H H R N C C N C H R R H C H B. H H C C H C H H H H H H C C C C H H H H H H H H H C C C C C C C C H H H H H H C C H H H H C C C C H H H H H H C. CH 3 H D. CH 3 CH 2 CH 2 CH 2 CH 2 9. The graph shows the relative number of atoms in a molecule. Relative number of atoms in a molecule 3 2 1 0 P H C N Type of atom Which of the following molecules reflects the data shown by the graph? A. ATP B. DNA C. ribose D. hemoglobin Page 4 Biology 12 0708 Form A

10. Which of the following molecules is stored in the liver and broken down when the body needs energy? A. starch B. maltose C. cellulose D. glycogen 11. What type of molecule is hemoglobin? A. a steroid B. a protein C. a nucleic acid D. a carbohydrate Use the following diagram to answer question 12. P S S P Y P P S S P P S S 12. and Y could represent which of the following? A. adenine and uracil B. guanine and cytosine C. cytosine and adenine D. thymine and thymine Biology 12 0708 Form A Page 5

13. Which of the following is a difference between RNA and DNA? A. the number of strands B. the presence of adenine C. the presence of guanine D. the presence of a five-carbon sugar Use the following diagram to answer question 14. 14. Which of the following correctly describes this process? A. Translation is occurring in the nucleus. B. Replication is occurring in the nucleus. C. Transcription is occurring in the nucleus. D. Translation is occurring in the cytoplasm. 15. The sequence of bases in a portion of a DNA molecule is C C G T A C. Which of the following represents the sequence of bases in the corresponding codons? A. CCG TAC B. CCG UAC C. G G C A T G D. GGC AUG Page 6 Biology 12 0708 Form A

Use the following diagram to answer question 16. G A A 16. Which DNA base sequence corresponds to the sequence of bases at? A. C T T B. C U U C. GAA D. GUU 17. Which of the following molecules is produced during translation? A. DNA B. trna C. protein D. mrna Biology 12 0708 Form A Page 7

Use the following chart to answer question 18. Three-letter codons of messenger RNA and the amino acids specified by the codons AAU AAC Asparagine CAU CAC Histidine GAU GAC Aspartic acid UAU UAC Tyrosine AAA AAG Lysine CAA CAG Glutamine GAA GAG Glutamate UAA UAG Stop ACU ACC ACA ACG Threonine CCU CCC CCA CCG Proline GCU GCC GCA GCG Alanine UCU UCC UCA UCG Serine AGU AGC AGA AGG Serine Arginine CGU CGC CGA CGG Arginine GGU GGC GGA GGG Glycine UGU UGC UGA UGG Cysteine Stop Tryptophan AUU AUC AUA AUG Isoleucine Methionine CUU CUC CUA CUG Leucine GUU GUC GUA GUG Valine UUU UUC UUA UUG Phenylalanine Leucine 18. Which of the following correctly matches the amino acid, codon and anticodon? Amino acid Codon Anticodon A. alanine G C C C G G B. proline GGC CCG C. isoleucine TAT AUA D. asparagine A A C T T G 19. By which of the following processes do oxygen and carbon dioxide move across the membranes of the alveoli? A. osmosis B. diffusion C. pinocytosis D. active transport Page 8 Biology 12 0708 Form A

Use the following diagram to answer question 20. W Y 20. Which structure can act as a glucose carrier? A. W B. C. Y D. Z Z 21. What is the process by which the sodium-potassium pump moves ions across the cell membrane? A. osmosis B. diffusion C. active transport D. facilitated transport Biology 12 0708 Form A Page 9

Use the following diagram to answer question 22. Time 22. What is the process shown in the diagram if contains polypeptide molecules? A. exocytosis B. pinocytosis C. phagocytosis D. facilitated transport 23. A 0.9% solution of sodium chloride is isotonic to red blood cells. Which of the following will result when the cells are placed in a 0.3% solution of NaCl? A. Water will move into the cells causing lysis. B. Water will move out of the cells causing lysis. C. Water will move into the cells causing crenation. D. Water will move out of the cells causing crenation. Page 10 Biology 12 0708 Form A

Use the following diagram to answer question 24. 10% 5% Time 1 hour? Membrane 24. In an experiment, the bottom of a thistle tube is covered with a membrane permeable only to water. The thistle tube is filled with a 10% sucrose solution and placed in a beaker containing a 5% sucrose solution. What will happen to the solution in the tube after one hour? A. The concentration of sucrose will decrease and become isotonic to the solution in the beaker. B. The concentration of sucrose will increase and become isotonic to the solution in the beaker. C. The concentration of sucrose will decrease and become hypotonic to the solution in the beaker. D. The concentration of sucrose will increase and become hypotonic to the solution in the beaker. 25. How do enzymes increase the rate of a chemical reaction? A. They denature the substrate. B. They decrease the energy of activation. C. They increase the substrate concentration. D. They donate atoms or ions to the reactants. Biology 12 0708 Form A Page 11

Use the following graph to answer question 26. W Potential energy Y Z Progress of reaction 26. Which line indicates the change in potential energy in a reaction when no enzyme is available? A. W B. C. Y D. Z 27. The activation energy required to initiate a metabolic reaction may be increased by the addition of A. heat. B. a substrate. C. an enzyme. D. an inhibitor. Page 12 Biology 12 0708 Form A

+ Use the following diagram to answer questions 28 and 29. Z Y 28. If is a carbohydrate, what are Y and Z? A. nucleotides B. amino acids C. glucose and maltose D. fatty acid and glycerol 29. Which of the following is? A. a product B. a reactant C. an enzyme D. an enzyme-substrate complex 30. Where does the emulsification of fat occur? A. the liver B. the colon C. the gall bladder D. the small intestine Biology 12 0708 Form A Page 13

Use the following diagram to answer question 31. Y 31. What is a difference between the contents in this structure at and at Y? A. There is more bile at than Y. B. There is less lipase at than Y. C. There is more water at than Y. D. There is less protein at than Y. 32. What organ produces pepsinogen? A. the liver B. the stomach C. the pancreas D. the duodenum 33. Which of the following correctly matches a digestive enzyme and the ph it requires to function at an optimum rate? Enzyme ph A. bile acidic B. pepsin basic C. trypsin basic D. nuclease acidic Page 14 Biology 12 0708 Form A

Use the following diagram to answer question 34. Y W Z 34. Which indicated structure secretes a hormone which causes increased production of glycogen? A. W B. C. Y D. Z Use the following diagram to answer question 35. 35. Where could the structure shown above be located? A. in the aorta B. in a lymph vein C. in a renal capillary D. in an umbilical artery Biology 12 0708 Form A Page 15

Use the following diagram to answer questions 36 and 37. W Y Z 36. Which arrow indicates the subclavian artery? A. W B. C. Y D. Z 37. At which point would the highest blood pressure be measured? A. W B. C. Y D. Z Page 16 Biology 12 0708 Form A

Use the following diagram to answer question 38. 38. Which of the following best describes the structure labelled? A. a vein which carries blood rich in glucose B. a vein which carries oxygenated blood to the heart C. an arteriole which carries blood to the small intestine D. an artery which carries nutrients to the rest of the body 39. In which structure does blood contain the greatest concentration of oxyhemoglobin? A. the aorta B. the right atrium C. the pulmonary artery D. the anterior vena cava Biology 12 0708 Form A Page 17

Use the following diagram to answer questions 40 and 41. Y Z W 40. Which of the indicated blood components contains reduced hemoglobin (HHb)? A. W B. C. Y D. Z 41. Which of the indicated blood components initiates blood clotting? A. W B. C. Y D. Z 42. Where are the chordae tendineae found? A. in the atria B. in the ventricles C. in the coronary arteries D. in the semilunar valves Page 18 Biology 12 0708 Form A

43. A person s blood pressure reading is measured at 150/80. Which of the following is greater than normal? A. systolic pressure B. diameter of veins C. diastolic pressure D. capillary diameter 44. Rings of cartilage surround which of the following structures? A. the alveoli B. the bronchi C. the pharynx D. the bronchioles 45. What structure is lined with cilia? A. the trachea B. the pharynx C. the epiglottis D. the pleural membranes 46. What structures increase the surface area in the lungs? A. the villi B. the alveoli C. the bronchi D. the pleural membranes 47. Which of the following causes a drop in the air pressure within the thoracic cavity? A. The rib cage moves up and out. B. Air moves into the thoracic cavity. C. The diaphragm becomes dome shaped. D. The medulla oblongata sends fewer nerve impulses. Biology 12 0708 Form A Page 19

Use the following diagram of alveoli to answer questions 48 and 49. Y 48. What is a characteristic of the blood in vessel Y if it is carrying blood toward? A. The concentration of oxyhemoglobin is high. B. The concentration of bicarbonate ions is high. C. The concentration of reduced hemoglobin is low. D. The concentration of carbaminohemoglobin is low. 49. Which of the following is a characteristic that aids in the function of structure? A. They have lipoproteins to prevent collapse. B. They have cilia and mucus to remove debris. C. They have a two or three cell layer thickness to provide strength. D. They have a low surface-area-to-volume ratio to allow for quick exchange of gases. 50. How does the body respond to increased concentration of carbon dioxide in the blood? A. Activity in the medulla oblongata decreases. B. Rate of contraction of the rib muscles increases. C. Number of impulses sent to the diaphragm decreases. D. Secretion of hormones from the hypothalamus increases. Page 20 Biology 12 0708 Form A

Use the following diagram to answer question 51. 51. What is the structure shown in the diagram? A. a reflex arc B. a motor neuron C. a sensory neuron D. a synaptic ending 52. What structure conducts nerve impulses from the spinal cord to the gall bladder? A. an effector B. an interneuron C. a motor neuron D. a sensory neuron Biology 12 0708 Form A Page 21

Use the following graph to answer questions 53 and 54. Membrane potential vs. Time +40 Membrane potential (millivolts) 0 membrane potential (millivolts) 65 Y Z Time 53. What describes the characteristics of a neuron from time period to Y? A. The sodium gates are open. B. The outside of the neuron becomes positively charged. C. The sodium-potassium pump moves potassium ions to the outside. D. The concentration of potassium ions outside the axoplasm is higher than inside. 54. What results if the potassium gates do not open during time Y to Z? A. Repolarization does not occur. B. The frequency of action potentials increases. C. The sodium-potassium pump does not function. D. The contractile proteins pull the vesicles to the membrane. 55. Which of the following occurs first when neurotransmitters bind to receptor sites on the postsynaptic membrane? A. Potassium ions diffuse out of the axon. B. Sodium ions diffuse into the axoplasm. C. Potassium ions are pumped out of the axoplasm. D. Membrane potential changes from +40 mv to 65 mv. Page 22 Biology 12 0708 Form A

Use the following diagram to answer question 56. Z Y W 56. To where does the nerve impulse travel after it leaves the axon of the motor neuron? A. W B. C. Y D. Z Use the following diagram of the brain to answer question 57. 57. What is structure? A. the thalamus B. the cerebellum C. the hypothalamus D. the corpus callosum Biology 12 0708 Form A Page 23

58. Which structure does urine enter after leaving the collecting duct? A. the ureter B. the urethra C. the renal pelvis D. the renal medulla Use the following diagram to answer question 59. Z Y W 59. What area represents the renal medulla? A. W B. C. Y D. Z Page 24 Biology 12 0708 Form A

Use the following diagram of a nephron to answer questions 60 and 61. W Y V Z 60. What occurs at structure W? A. Less water is reabsorbed when ADH is secreted. B. Materials are forced into the tubule by pressure filtration. C. Substances are actively transported from the blood to the filtrate. D. Materials are reabsorbed from the filtrate into the peritubular capillary network. 61. Where does the filtrate have the highest concentration of amino acids? A. V B. C. Y D. Z Biology 12 0708 Form A Page 25

62. Which of the following conditions results in fewer hydrogen ions being excreted into the urine? A. increased blood ph B. decreased blood ph C. secretion of aldosterone D. secretion of antidiuretic hormone (ADH) 63. Fertilization usually takes place in the A. ovary. B. uterus. C. cervix. D. oviducts. 64. Which phase occurs on days 15 28 of the uterine cycle? A. the luteal phase B. the follicular phase C. the secretory phase D. the proliferative phase Page 26 Biology 12 0708 Form A

65. Which of the following occurs as a result of a sudden increase in the concentration of luteinizing hormone (LH) in the blood? A. ovulation B. a follicle begins to develop C. the endometrium begins to disintegrate D. the corpus luteum begins to break down Use the following diagram to answer question 66. Z Y W 66. The stimulation of which structure results in the release of oxytocin during childbirth? A. W B. C. Y D. Z Biology 12 0708 Form A Page 27

Use the following diagram of an ovary to answer question 67. Y Time W Z 67. Which structure is maintained by the secretion of human chorionic gonadotropin (HCG)? A. W B. C. Y D. Z You have Examination Booklet Form A. In the box above #1 on your Answer Sheet, ensure you filled in the bubble as follows. Exam Booklet Form/ Cahier d examen A B C D E F G H This is the end of the multiple-choice section. Answer the written-response questions in the Response Booklet. Page 28 Biology 12 0708 Form A

MINISTRY USE NLY MINISTRY USE NLY Question 1 0 1 2 3 NR Question 2 0 1 2 3 4 NR Place Personal Education Number (PEN) here. Question 3 0 1 2 3 4 NR Question 4 0 1 2 3 NR Course Code = BI AUGUST 2007 12 Question 5 0 1 2 3 4 NR Exam Booklet Form/, Cahier d examen A B C D E F G H Question 6 0 1 2 3 4 5 NR Student Instructions 1. Place your Personal Education Number (PEN) label at the top of this Booklet AND fill in the bubble (Form A, B, C, D, E, F, G or H) that corresponds to the letter on your Examination Booklet. 2. Use a pencil to fill in bubbles when answering questions on your Answer Sheet. 3. Use a blue- or black-ink pen when answering written-response questions in this Booklet. 4. Read the Examination Rules on the back of this Booklet. 30237 Version 0708.1

MINISTRY USE NLY Place Personal Education Number (PEN) here. Course Code = BI 12 Biology 12 AUGUST 2007 Response Booklet Province of British Columbia

PART B: WRITTEN RESPNSE Value: 23 marks Suggested Time: 40 minutes INSTRUCTINS: 1. Answer the following questions in the space provided in this Response Booklet. 2. Use a pen for this part of the examination unless otherwise instructed. 3. You may not need all of the space provided to answer each question. 1. (3 marks) Describe the steps involved when a DNA molecule is copied. Biology 12 0708 Response Booklet Page 1

2. (4 marks) Compare the chemical composition of the contents of the stomach one hour after eating a meal containing proteins, carbohydrates and fats, to the contents of the small intestine several hours later. Page 2 Biology 12 0708 Response Booklet

Use the following diagram of blood and tissue cells in the placenta to answer question 3. From umbilical artery Y To umbilical vein 3. (4 marks) Describe the differences in the chemical composition of the blood as it moves from to Y. Biology 12 0708 Response Booklet Page 3

4. (3 marks) Describe and explain the effect an absence of calcium ions would have on the transmission of an action potential. Page 4 Biology 12 0708 Response Booklet

5. (4 marks) Explain why excessive aldosterone secretion leads to edema, a condition that results in the swelling of tissues due to retention of fluids. Biology 12 0708 Response Booklet Page 5

6. (5 marks) Compare the effects of hormones secreted by the anterior pituitary on the male and female reproductive systems. END F EAMINATIN Page 6 Biology 12 0708 Response Booklet

Examination Rules 1. The time allotted for this examination is two hours. You may, however, take up to 60 minutes of additional time to finish. 2. Answers entered in the Examination Booklet will not be marked. 3. Cheating on an examination will result in a mark of zero. The Ministry of Education considers cheating to have occurred if students break any of the following rules: Students must not be in possession of or have used any secure examination materials prior to the examination session. Students must not communicate with other students during the examination. Students must not give or receive assistance of any kind in answering an examination question during an examination, including allowing one s paper to be viewed by others or copying answers from another student s paper. Students must not possess any book, paper or item that might assist in writing an examination, including a dictionary or piece of electronic equipment, that is not specifically authorized for the examination by ministry policy. Students must not copy, plagiarize or present as one s own, work done by any other person. Students must immediately follow the invigilator s order to stop writing at the end of the examination time and must not alter an Examination Booklet, Response Booklet or Answer Sheet after the invigilator has asked students to hand in examination papers. Students must not remove any piece of the examination materials from the examination room, including work pages. 4. The use of inappropriate language or content may result in a mark of zero being awarded. 5. Upon completion of the examination, return all examination materials to the supervising invigilator.