Adult Respiratory Distress - The Unresponsive Patient

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Adult Respiratory Distress - The Unresponsive Patient Monitoring (blood pressure, heart rate, pulse oximetry, respiratory rate) ongoing throughout evaluation and management. All initial actions are performed simultaneously after verification of unresponsiveness by stimulating the patient including head tilt and jaw lift. Reversal agents (naloxone and flumazenil) may be administered at any time. Clinical Condition Respiratory rate >10 and Oxygen saturation > 95% Clinical Condition Respiratory rate <10 and/or Oxygen saturation <95% Clinical Condition Breathing Normally and Unresponsive Step 1 Step 2 Step 3 Step 4 Step 1 Step 2 Step 3 Verify unresponsiveness. Call for emergency equipment. Monitor patient. Open the airway with head tilt, chin lift, and jaw thrust. Ammonia vaporole respiratory stimulant. Supplemental oxygen with Non-rebreathing face mask 15 L/minute or Nasal cannula/nasal hood 4 L/minute. Raise the legs. Reversal agent(s) if indicated. Action Respiratory deterioration. Raise the legs. Respiratory Depression and Unresponsive Action Verify unresponsiveness. Call for emergency equipment. Monitor patient. Open the airway with head tilt, chin lift, and jaw thrust. Ammonia vaporole respiratory stimulant. Raise the legs. Ventilation Management (see below) Reversal agent(s) if indicated. Apnea with Carotid Pulse Action Ventilation Management (see below) Step 1 Verify unresponsiveness. Call for emergency equipment. Monitor patient. Respiratory rate 0 Step 2 Open the airway with head tilt, chin lift, and jaw thrust. Verify not breathing. Check Pulse oximeter (BP >80 systolic) and/or Carotid pulse present (BP >60 systolic) which indicate chest compressions not needed. Step 3 Raise the legs. Step 4 Reversal agent(s) if indicated. Ventilation Management (see below) Apnea without Carotid Pulse - see Adult Cardiac Management Ventilation Management - Apnea / Hypoventilation / Obstruction Step 1 Open the airway with head tilt, chin lift, and jaw thrust. Step 2 Consider oral or nasal airway if apneic. Step 3 Bag Mask ventilation - preferably two person. One breath every 6 seconds, breath volume 400-800 ml, pressure <20 cm H 2 O, oxygen flow 15 L/minute. Step 4 Confirm chest rise with each breath. Step 5 Consider advanced supraglottic airway with gastric venting capacity if unable to ventilate with bag mask easily. Step 6 Confirm supraglottic airway placement with chest rise. Step 7 If no chest rise seen after advanced airway placement, continue with evaluation for larynospasm, foreign body, bronchospasm, or chest wall rigidity. Ten Minutes Saves A Life! is a registered trademark of the ADSA Anesthesia Research Foundation / 2013 EmergSim LLC / 10Min Resp Mgmt 131108 (1)

Respiratory Distress: Oxygenation - Airway - Ventilation Algorithm Office Team with AHA BLS HP Training Primary Assessment Airway, Breathing, Oxygen Saturation Supplemental Oxygen 4 L/min Nasal Cannula or 15 L/min Mask (Non-rebreathing) Breathing Status Breathing Continue Oxygen Apnea Bag Mask 15 L/min Oxygen SpO 2 Status > 95 < 95 > 95 < 95 Interventions Monitor & Support Assist Ventilation: Continue Bag Mask Oral or Nasopharyngeal Airway Consider Reversal Agent * Bag Mask 10 Breaths/min Reversal Agent * Consider Supraglottic Airway Reversal Agent * [SpO 2 >95] Reversal Agent * [SpO 2 <95] Consider Oral or Nasopharyngeal Airway Reversal Agent * * Reversal Agents may be administered simultaneously with other interventions. Ten Minutes Saves A Life! is a registered trademark of the ADSA Anesthesia Research Foundation / 2013 EmergSim LLC / 10Min Airway Vent Team 131108 (2)

Adult Cardiac Emergency Management Office Team with AHA BLS HP and ACLS Training Responsive with Chest Pain: ACS Diagnosis Acute Coronary Syndrome (ACS) symptoms Chest, arm, or face discomfort / pressure Diaphoresis Syncope Hemodynamic instability Unresponsive with Apnea and Carotid Pulse Absent Apnea No pulse oximeter reading Carotid pulse absent Step 1 Assistance and Emergency Medical Service (EMS) called. Call for emergency equipment. Monitor patient. Step 2 Supplemental oxygen: Face mask non-rebreathing 15 L/min or Nasal cannula/nasal hood 4 L/min. Nitroglycerin 0.4 mg tablet sublingual or metered spray dose if blood pressure >90 systolic and heart rate > 50. Aspirin 325 mg tablet or 81 mg x 4 tablets chew and swallow. Step 3 Repeat nitroglycerin 0.4 mg in 5 minutes if pain persists and blood pressure >90 systolic. Step 1 Assistance and EMS called. Call for emergency equipment. Step 2 Begin chest compression at 100/minute for 30 compressions. Turn on AED and follow directions. Step 3 Insert oral airway and deliver 2 bag-mask ventilations at the end of each 30 chest compression cycle. Advanced Airway placement as soon as possible - See Adult Respiratory Management. Step 4 Continue with 30 chest compressions and 2 bag-mask ventilations five (5) times or until AED says stop to analyze rhythm. Step 5 AED will indicate either shock recommended (V-fib or pulseless V-tach) or no shock recommended (PEA/Asystole) - see below. Optimizing CPR AED Indicates Shock AED Indicates No Shock AED 2 minute timer is activated once unit is turned on. Practitioner should check carotid pulse at end of each 2 minute interval of chest compressions while AED is analyzing ECG rhythm. With bag-mask ventilation the 2 minute interval of chest compressions to ventilations at a ratio of 30-2 for 5 cycles provides 150 chest compressions and 10 ventilations. Additionally, the coronary and cerebral perfusion pressures drop with each pause and require ~ 3 compressions to peak again. With placement of an LMA/advanced airway, compressions and ventilations are continuous resulting in 200 compressions and 20 ventilations for the 2 minute interval. Additionally, the coronary and cerebral perfusion pressures are maintained throughout the 2 minute interval. Chest compressions are optimized at a depth of at least 2 inches / 50 mm and a rate of 100/minute. Good chest recoil is necessary to fill the heart. Change the individual performing chest compressions at the end of each 2 minute interval. Step 1 AED charges and practitioner clears and defibrillates #1. Step 2 Resume CPR for 2 minutes per AED timer. Step 3 Two minute interval complete. AED analyzes ECG rhythm and carotid pulse absent. AED indicates shock. Step 4 AED charges and practitioner clears and defibrillates #2. Step 5 Resume CPR and administer epinephrine 1 mg in prefilled syringe 1:10,000 10 ml IV followed by flush. Step 6 Two minute interval complete. AED analyzes ECG rhythm and caroitid pulse absent. Step 7 AED charges and practitioner clears and defibrillates #3. Step 8 Resume CPR and administer amiodarone 300 mg/iv followed by flush. Step 9 Two minute interval complete. AED analyzes ECG rhythm and carotid pulse absent. AED indicates shock. Step 10 AED charges and practitioner clears and defibrillates #4. Step 11 Resume CPR and administer epinephrine 1 mg in prefilled syringe 1:10,000 10 ml IV followed by flush. Step 12 CPR continues at 2 minute intervals until EMS arrives. Step 1 Resume CPR and administer epinephrine 1 mg in prefilled syringe 1:10,000 10 ml IV followed by flush. Step 2 Two minute interval complete. AED analyzes ECG rhythm and carotid pulse absent. AED still indicates no shock. Step 3 Resume CPR. Step 4 Two minute interval complete. AED analyzes ECG rhythm and carotid pulse absent. AED still indicates no shock. Step 5 Resume CPR and administer epinephrine 1 mg in prefilled syringe 1:10,000 10 ml IV followed by flush. Step 6 CPR continues at 2 minute intervals until EMS arrives. Ten Minutes Saves A Life! is a registered trademark of the ADSA Anesthesia Research Foundation / 2013 EmergSim LLC / 10Min Cardiac ACLS 131108 (3)

Reversal / Respiratory Depression Chest Pain: Stable Angina / Acute Coronary Syndrome (Unstable Angina / MI) Flumazenil Naloxone Nitroglycerin Fentanyl 50 mcg/ml or Aspirin (not enteric coated) 0.1 mg/ml 0.4 mg/ml 0.4 mg tablet or spray Morphine 10 mg/ml 325 mg tablet x 1 or 10 ml Syringe 1 ml Syringe SL: 1 tab/spray q 5 min x 3 1 ml Syringe 81 mg tablets x 4 Administer only if blood pressure Fentanyl Morphine Chew and swallow IV: 0.2 mg = 2 ml IV, IM or SLI: 0.2-0.4 mg >90 and heart rate >50. IV, IM or SLI: IV, IM or SLI: 325 mg tablet x 1 or 25-50 mcg = 2 mg = 0.2 ml x 5 doses q 1 min = 0.5-1.0 ml Assume ACS if no relief 81 mg tablets x 4 0.5-1 ml following first dose Bradycardia Hypotension Cardiac Arrest Atropine Ephedrine Epinephrine 1:10,000 Vasopressin Amiodarone Lidocaine or 1 mg/ml vial 50 mg/ml 0.1 mg/ml 20 units/ml 50 mg/ml 20 mg/ml 1 ml Syringe 1 ml vial x 2 3 ml vial x 3 IV, IM, or SLI: 1 ml Syringe Prefilled Syringe 5 ml Syringe 10 ml Syringe Prefilled Syringe 0.5 mg = 0.5 ml 0.1 mg/ml Prefilled Syringe IV: 0.5 mg = 5 ml Diphenhydramine 50 mg/ml 1 ml Syringe IM: 50 mg = 1 ml IV: Dilute 1 ml in 10 ml syringe to 5 mg/ml Deliver 25 mg=5 ml Drug Management for Adult Emergencies - AHA BLS HP and ACLS Provider 1) Primary Assessment: Responsiveness, Pulse, Ventilation, Oxygenation SpO2, BP 2) Initial Management: Oxygenation and Ventilation (nasal cannula, face mask, BVM), Circulation (raise legs, chest compressions, defibrillation) 3) Determine diagnosis for drug administration or IV: 5 mg=0.1 ml IM or SLI: 10 mg = 0.2 ml Allergy / Asthma - Bronchospasm Albuterol 90 mcg metered inhaler 2 inhalations x 3 Requires cooperative patient IV: 1 mg = 10 ml Epinephrine 1:1000 1 mg/ml 1 ml Syringe or auto-injector IM: 0.3 mg = 0.3 ml 1:10,000 0.1 mg/ml Prefilled Syringe Only if life-threatening IV: 0.1 mg = 1 ml increments IV: 40 units/2 ml 1 dose per ACLS Auto-injector / Epi-pen Auto inject 0.3 mg over 10 sec IV: 300 mg 6 ml Initial per ACLS Anaphylaxis / Laryngeal Edema Epinephrine 1:1000 1 mg/ml Vastus lateralis or deltoid Repeat if necessary Hypoglycemia Laryngospasm Glucose Oral 15 or 24 g tube Glucagon Kit Succinylcholine 20 mg/ml (Refrigerated) Only conscious patient 1 mg vial + 1 ml sterile water 1 ml Syringe slowly swallow oral delivery 1 mg IV or IM IV or IM 20 mg = 1 ml IM=Intramuscular Vastus Lateralis or Deltoid / IV=Intravenous / SLI=Sublingual submucosal injection / SL=Sublingual mucosal topical IV: 1.5 mg/kg Initial per ACLS 1 ml syringe IM: 0.3 mg = 0.3 ml Ten Minutes Saves A Life! is a registered trademark of the ADSA Anesthesia Research Foundation / 2013 EmergSim LLC / 10Min Emerg Drugs 131108 (4)

Adult Emergency - Drug Management (CPR excluded) AHA BLS HP and ACLS + General anesthesia training Respiratory Depression / Over Sedation / Respiratory Soft Tissue Obstruction Naloxone Opioid antagonist 0.4 mg/ml IV or IM: 0.4 mg (1 ml) utes Flumazenil Benzodiazepine antagonist 0.1 mg/ml IV: 0.2 mg (2 ml) q 1 minute Bradycardia Atropine Anticholinergic 1 mg/ml IV or IM: 0.5 mg (0.5 ml) utes Anticholinergic 0.1 mg/ml 10 ml prefilled syringe IV: 0.5 mg (5 ml) utes Hypotension Ephedrine Alpha and beta agonist 50 mg/ml IV: 10-25 mg (0.2-0.5 ml) q 3-5 minutes Hypoglycemia Glucose oral Carbohydrate 15 or 24 gram tube Contents slowly swallowed. Only for conscious patiient. Glucagon Allergic Reaction Mild Induces liver glycogen breakdown and glucose release 1 mg with 1 ml diluent IV, IM or SC 1 mg (1mL) Diphenhydramine Histamine H1 antagonist 50 mg/ml IM: 25 mg (0.5 ml). May need to repeat. Anaphylaxis / Laryngeal Edema Epinephrine Alpha and beta agonist 1:1000 in 1 mg/ml vial IM: 0.3 mg (0.3 ml). May need to repeat. Bronchospasm 1:1000 auto-injector adult 0.3 mg Auto-inject IM: 0.3 mg. May need to repeat. Albuterol Selective beta-2 agonist 90 mcg/dose metered inhaler 2 inhalations. Epinephrine IM if ineffective. 1:1000 in 1 mg/ml IM: 0.3 mg (0.3 ml). May need to repeat. Epinephine Alpha and beta agonist Cardiovascular compromised patient consider reduced dose. Severe bronchospasm 1:1000 auto-injector adult 0.3 mg Auto-inject IM: 0.3 mg. May need to repeat. Laryngospasm Succinylcholine Paralysis 20 mg/ml IV or IM: 20 mg (1 ml) Ten Minutes Saves A Life! is a registered trademark of the ADSA Anesthesia Research Foundation / 2013 EmergSim LLC / 10Min Emerg Drugs 131108 ACLS (5)

Emergency Drug List Adult Medical Emergency Management AHA BLS HP and ACLS Albuterol Inhalation Metered Inhaler (90 mcg/actuation) Amiodarone 50 mg/ml 3 ml vial three Drugs Epinephrine 1:10,000 0.1 mg/ml 10 ml prefilled syringe two Flumazenil 0.1 mg/ml 10 ml vial (or 5 ml vials two) Syringes and Needles for Administration 1 ml syringe with 21 gauge 1 inch needle four 5 ml syringe with 21 gauge 1.5 inch needle two Aromatic Ammonia Inhalant Vaporole(s) two Aspirin 81 mg tablets - four or Aspirin 325 mg tablets (not enteric coated) unit dose package Atropine 1 mg/ml 1 ml vial Atropine 0.1 mg/ml 10 ml prefilled syringe Diphenhydramine 50 mg/ml 1 ml vial Glucose Oral 15 gram tube two (or 24 gram tube one) Glucagon Kit 1 mg vial + 1 ml sterile water Naloxone 0.4 mg/ml 1 ml vial Nitroglycerin 0.4 mg tablets Nitroglycerin 0.4 mg/dose pump spray bottle Succinylcholine 20 mg/ml 10 ml vial (Refrigerated) 10 ml syringe with 21 gauge 1.5 inch needle - two 20 ml syringe + 21 gauge 1 inch needle Ten Minutes Saves A Life! is a registered trademark of the ADSA Anesthesia Research Foundation 2013 EmergSim LLC 10Min EmergDrugs ACLS 131203 (6A) Ephedrine 50 mg/ml 1 ml vial Vasopressin 20 units/ml 1 ml vial two Epinephrine 1:1,000 1 mg/ml 1 ml vial Epinephrine auto-injectors (0.3 mg/actuation) - two

Oxygenation, Ventilation, Airway Equipment Adult Emergency Management AHA BLS HP and ACLS Ten Minutes Saves a Life! Oxygen E tank (alloy) with regulator (integral or detachable with key), pressure gauge, and flow meter (1-15L/minute) Suction handle with Yankauer tip, suction tubing, and vacuum high volume system adapter Nasal cannula adult Face mask non-rebreather adult Resuscitation bag adult 800-1100 ml stroke volume with pressure manometer (with or without pressure-limiting valve and override), face mask, oxygen reservoir bag, and oxygen tubing Nasopharyngeal airways (poly vinyl chloride): 24 Fr / 6.0 mm I.D 26 Fr / 6.5 mm I.D. 28 Fr /7.0 mm I.D. 30 Fr 7.5 mm I.D. Oropharyngeal airways (Guedel): 80 mm, 90 mm, and 100 mm Laryngeal Supraglottic Airways - gastric venting Size 3 (30-60 kg) Size 4 (50-90 kg) Size 5 (90 kg+) Stethoscope + Sphygmomanometer with adult standard and large cuffs Magill forceps Practitioner with advanced airway intubation training: Larynogoscope handle - practitioner preference Larynogoscope blade(s) - practitioner preference Endotracheal tubes: 6.0 / 6.5 / 7.0 / 7.5 Endotracheal tube stylet Eschmann introducer/bougie 10 ml syringe End-tidal carbon dioxide detector End-tidal monitor adapter and tubing for attachment to LMA, ET, and mask Albuterol aerosol holding chamber for resuscitation bag (e.g. Aero Chamber mini, Monoghan) - optional Ten Minutes Saves A Life! is a registered trademark of the ADSA Anesthesia Research Foundation / 2013 EmergSim LLC / 10Min Equip ACLS 131203 (6B)

Adult Emergency Drugs AHA BLS HP and ACLS 10 Minutes Saves A Life! Amiodarone Flumazenil Naloxone Atropine Prefilled Syringe Aspirin Succinylcholine (Refrigerated) Atropine Vasopressin Nitroglycerin Diphenhydramine Epinephrine 1:10,000 Prefilled Syringes Syringes and Needles Optional Ephedrine Epinephrine Albuterol Inhaler Epinephrine 1:1,000 auto-injectors Glucose Oral Aromatic Ammonia Glucagon Nitroglycerin pump spray bottle Ten Minutes Saves A Life! is a registered trademark of the ADSA Anesthesia Research Foundation 2013 EmergSim LLC / 10Min Drug Case 131203 (7)