Tactile Internet and Edge Computing: Emerging Technologies for Mobile Health

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Tactile Internet and Edge Computing: Emerging Technologies for Mobile Health Zaher Dawy, PhD Department of Electrical and Computer Engineering American University of Beirut http://www.aub.edu.lb/~zd03 Tactile Internet Sub-Committee IEEE ICC 2017, Paris

Can a surgeon control the da Vinci robot from outside the operation room?

Can a gastroenterologist in Paris perform remote endoscopy for a patient in Beirut?

Not yet! Ultra low e2e delays (??? ms) Ultra high reliability (??? %) High quality broadband (??? Mbps) Positioning accuracy (??? mm) Security and privacy, 10,000 Km 33 ms

Plan to define ehealth use case for the Tactile Internet standard. If you are interested to contribute, please email: zd03@aub.edu.lb

Mobile health for neurological applications EEG ECG Cellular 2 Blood pressure Hydration WIFI WIFI WIFI - Remote diagnosis - Predictive analytics - Emergency notifications 3 Motion 1 Dynamic on-demand sensing Wearable sensing Mobile computing Cloud analytics

with focus on Epilepsy 75% of affected people in developing countries do not get treatment 30% of the time, epilepsy patients do not respond to treatment Risk of sudden death among epilepsy patients is 24x greater More than 50 million people worldwide are affected by epilepsy and the mortality rate among people with epilepsy is 2-3x higher than the general population For epilepsy sufferers, one of the most frustrating aspects is not knowing when a seizure will occur

DSI 24: Research grade wireless EEG headset Designed for rapid application of 21 s at locations Properties: Self-donned and ready to record EEG in under 5 minutes Portable design suitable for light ambulation in office or lab environment 21 s positioned according to the 10-20 International System Continuous impedance monitoring Bluetooth wireless transmission with sampling at 300Hz Possible Usages: Adapting the prediction process to noisy signals through identifying specific and defined Artifacts from lab-acquired EEG data: movement, blinking, tension, facial expressions, interferences, etc...

How much data does a mobile EEG headset generate per hour? 110 90 Data volume (MB) vs. recording setup 107 Cellular 70 50 30 54 10 0.03 0.89 1.84-10 1 min window, 1channel, 256 Hz 1 min, 29 channels, 256 Hz 1 hr window, 1 channel, 256 Hz 1 hr, 29 channels, 256 Hz 1 hr, 29 channels, 512 Hz

EEG When to sense and collect EEG data, and for how long? Where to process this data? How to process this data? What are delay, reliability, processing, & energy requirements? ECG Cellular Blood pressure Hydration WIFI WIFI WIFI - Remote diagnosis - Predictive analytics - Emergency notifications Motion Dynamic on-demand sensing Wearable sensing Mobile computing Cloud analytics

How to process? Seizure onset Offset Window Size Interval Length Epilepsy prediction: predict seizure onset seconds to minutes before Use case: Real time notification via mobile app Requirements: Very challenging to predict, but more complex processing can be handled in the cloud

How to process? Seizure onset Offset Window Size Interval Length Epilepsy detection: detect seizure onset as soon as it happens Use case: Automated deep brain stimulation Requirements: Relatively easy to detect, but all processing should be at the edge, using one or multiple cooperative devices

How to detect & predict epileptic seizures? Real time Self-learning Multi-dimensional Patient-centric Robust

N-gram based feature extraction for EEG signals Offset Window Size Interval Length Amp Patterns: 2 6 5 8 1 2 6 3 2 2 2 1 1 2 4 1 2 6 2 2 2 1 1 2 4 1 2 3 4 5 6 7 1 2 3 4 5 2 0 0 0 2 3 4 5 6 2 3 4 5 2 2 2 1 1 2 4 0 1 2 3 4 5 6 7 8 9 1 2 2 1 4 Significant pattern count per sub-interval: Anomalies Ratios per sub-interval: A1 A2 A3 A4 Ak Seizure onset C1 C2 C3 C4 Ck Controlling Parameters: - Window size - Interval Length - Pattern Length - Offset * Anomalies ratios are high before the seizure-onset 30 sec intervals

Epilepsy prediction: Sample results 120.00 100.00 80.00 60.00 40.00 20.00 0.00 P_1 P_73 P_89 P_110 P_162 P_219 P_226 P_239 P_261 P_300 P_308 P_325 P_327 P_454 P_467 P_586 P_852 90.91 92.86 100.00 100.00 75.00 100.00 86.11 100.00 87.50 95.00 100.00 87.50 100.00 100.00 100.00 87.50 90.00 90.91 85.71 100.00 100.00 83.33 100.00 83.33 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 95.00 90.00 9.09 0.00 0.00 0.00 33.33 0.00 11.11 0.00 25.00 10.00 0.00 25.00 0.00 0.00 0.00 20.00 10.00 TP TN TP TN Accuracy = Sensitivity = TP TN FP FN TP FN False Alarm = TN FP