ERS School Course Programme Lung Transplantation: Sharing Experience Across Europe February 23-25, 2012 Strasbourg, France

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ERS School Course Programme Lung Transplantation: Sharing Experience Across Europe February 23-25, 2012 Strasbourg, France Day 1: Thursday, Date 23. 02. 2012 08:30 08:45 Registration 08:45 09:00 Welcome and Identification of Participants Learning Needs - Andrew Fisher (United Kingdom) Session I: Lung Transplantation Introduction - Chair: Annette Boehler 09:00 09:20 History of lung transplantation - G. Massard 09:20 09:50 The Key Elements of a Lung Transplant Programme P. Corris 09:50 10:15 Coffee Break BASIC PROGRAMME Session II Candidate selection and management - Chair G. Verleden 10:15 11:00 Referral Guidelines (general principles and specific issues in CF, ILD, COPD and PH)- A. Boehler 11:00 11.30 Candidate selection: specific controversial issues (previous malignancies, chronic infections,..) P.Corris 11:30 12.00 Pre-surgical management of lung transplant candidates (from clinical to and psychological approaches) J. Gottlieb 12:00-12.30 Referral Criteria and Candidate Selection in COPD and PH F. Meloni 12:00-13:00 Mechanical ventilation in lung transplant recipients D. Van Raemdonck ADVANCED PROGRAMME Session II Candidate selection and management - Chair G. Verleden Referral Guidelines (general principles and specific issues in CF, ILD, COPD and PH)- A. Boehler Candidate selection: specific controversial issues (previous malignancies, chronic infections,..) P.Corris Pre-surgical management of lung transplant candidates (from clinical to and psychological approaches) J. Gottlieb Lung transplant bridge with Extracorporel devices (ECMO, NOVALUNG) M. Struber Mechanical ventilation in lung transplant recipients D. Van Raemdonck 13.00 14.00 Lunch For more information contact school@ersnet.org Page 1 of 6

Session III Donor organ availability- Chair F. Meloni 14:00 14:30 Identifying usable donor organs : pushing the boundaries G. Massard 14:00 14:30 Which donor features can affect graft outcome? - E. Verschuuren 14:30 15:00 Increasing Donation Rates: Lessons within Europe P. Thomas Session III Donor organ shortage- Chair D. Van Raemdonck Non heart beating donors: principles, regulations, ethical issues, and results - E. Verschuuren Size reduced lung transplant and living donor lung transplant - M. Struber Ex-Vivo Donor Lung Perfusion A. Fisher 15:00 Coffee Break 15:00 16:15 Interactive Workshops Case Examples and Discussion A. Candidate Selection A Boehler B. Donor Selection (including NHB protocol) - D. Van Raemdonck C. How to do a lung transplant G. Massard D. Bridging with ECMO and Novalung - M. Struber Interactive Workshops Case Examples and Discussion A. Candidate Selection A Boehler B. Donor Selection (including NHB protocol) - D. Van Raemdonck C. How to do a lung transplant G. Massard D. Bridging with ECMO and Novalung - M. Struber 16:15 17:30 Workshops Repeated Workshops Repeated 19:30 Welcome cocktail For more information contact school@ersnet.org Page 2 of 6

Day 2: Friday, Date 24. 02. 2012 BASIC PROGRAMME Session IV - Early Clinical Care of the Lung Transplant Recipient Chair P. Thomas 09:00 09:30 Pathophysiology and classification of PGD D. Van Raemdonck 09:30 10:00 Primary Graft Dysfunction- clinical management M. Struber 10:00 10:30 Acute cellular and humoral rejection - F. Meloni 10:30 10:45 Coffee Break 11:00 11:45 Interactive Workshops Case E. Organising Long Term Care - Faculty panel F. Challenges in post transplant lung pathology - J. Gottlieb G. Interactive discussion of proposed challenging cases (bridging and early post transplant care) - M. Struber, D. Van Raemdonck, G. Massard H. Hot Topics in Transplant Ethics P. Corris ADVANCED PROGRAMME Session IV - Challenges in early recipient management Chair M. Iversen New perspectives in PGD prevention and treatment J. Gottlieb Management of post transplant airway complications G. Massard Bronchoscopic monitoring after lung transplantation: actual role of TBB and BAL A. Boehler Interactive Workshops Case E. Organising Long Term Care - Faculty panel F. Challenges in post transplant lung pathology - J. Gottlieb G. Interactive discussion of proposed challenging cases (bridging and early post transplant care) - M. Struber, D. Van Raemdonck, G. Massard H. Hot Topics in Transplant Ethics P. Corris 11:45 12:30 Workshops Repeated Workshops Repeated 12.30 13.30 Lunch Session V - Immunosuppression and beyond. Chair : E. Verschuuren Session V - Immunosuppression and beyond. Chair : E. Verschuuren 13:30 14:00 Old and New Strategies in Induction therapy A. Boehler 14:00 14:30 Calcineurin inhibitors: Friend and Foe? - M. Iversen 14:30 15:00 Newer Immuno-suppressants: MMF and mtor Inhibitors P. Corris 15:00 15:30 Actual role of azythromycin: when and how - G. Verleden Old and New Strategies in Induction therapy A. Boehler Calcineurin inhibitors: Friend and Foe? - M. Iversen Newer Immuno-suppressants: MMF and mtor Inhibitors P. Corris Actual role of azythromycin: when and how - G. Verleden 15.30 16.00 Break For more information contact school@ersnet.org Page 3 of 6

Session VI - Infections in the Lung Transplant Candidate and Recipient. Chair P. Corris Session VI - Infections in the Lung Transplant Candidate and Recipient. Chair P. Corris 16:00 16:30 CMV management in lung transplant CMV management in lung transplant recipients E. Verschuuren recipients E. Verschuuren 16:30 17:00 Respiratory viral infections - F. Meloni Respiratory viral infections - F. Meloni 17:00 17:30 Aspergillus and Other Fungi - Geert Aspergillus and Other Fungi - Geert Verleden Verleden 17:30 18:00 Multiresistant Bacterial Infections - A. Fisher Multiresistant Bacterial Infections - A. Fisher 18:00 18:30 Participants case reports Participants case reports For more information contact school@ersnet.org Page 4 of 6

Day 3: Saturday, Date 25. 02. 2012 BASIC PROGRAMME Session VII - Bronchiolitis Obliterans Syndrome / Obliterative bronchiolitis - Chair E. Verschuuren 09:00 09:30 BOS/OB: aetiology and pathogenesis M. Iversen 09:30 10:00 Diagnosing and Managing BOS/OB A. Fisher 10:00 10:30 Retransplantation for graft failure: indications, outcomes and ethical issues G. Massard ADVANCED PROGRAMME Session VII - New insight in Chronic rejection diagnosis and treatment - Chair P. Corris BOS Sub-phenotyping, beyond lung function - G. Verleden Old and new therapeutic options in BOS A. Boehler Assessemnt and treatment of GER F. Meloni 10:30 11:00 Coffee Break Session VIII- Late Complications after Lung Transplantation - Chair A. Fisher 11:00 11:30 Renal Dysfunction and cardiovascular disorders M. Iversen 11:30 12:00 Lymphoproliferative Disease prevention and management E. Verschuuren 12: 00-12:30 Other malignancies prevention and treatment - F. Meloni 12:30 13:00 Panel discussion with faculty and participants Session VIII- Late Complications after Lung Transplantation - Chair A. Fisher Renal Dysfunction and cardiovascular disorders M. Iversen Lymphoproliferative Disease prevention and management E. Verschuuren Other malignancies prevention and treatment - F. Meloni Panel discussion with faculty and participants 13:00 14:00 Lunch Interactive Workshops Case Interactive Workshops Case 14:00 14:45 I. Managing BOS/OB G. Verleden I. Managing BOS/OB G. Verleden J. Managing post transplant J. Managing post transplant malignancies E. Verschuuren malignancies E. Verschuuren K. Infectious Complications A. Fisher K. Infectious Complications A. Fisher L. Interactive discussion of proposed L. Interactive discussion of proposed challenging cases (long term post challenging cases (long term post transplant complications) P. Corris, transplant complications) P. Corris, M. Iversen, F. Meloni M. Iversen, F. Meloni 14.45-15.30 Workshops Repeated Workshops Repeated 15:30 Closing Remarks For more information contact school@ersnet.org Page 5 of 6

For more information contact school@ersnet.org Page 6 of 6