A New Data Driven Approach to Analyzing the Impact of Social Policies on Health on a Global Scale

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A New Data Driven Approach to Analyzing the Impact of Social Policies on Health on a Global Scale Arijit Nandi, arijit.nandi@mcgill.ca Department of Epidemiology, Biostatistics and Occupational Health Département d épidémiologie, biostatistique et santé au travail

The UN Development Goals represent global commitments to achieve significant and defined progress in global health. MDG (1990-2015) SDG (2015-2030) MDG4. Reduce child mortality Reduce under-five mortality by two-thirds SDG 3.2. Lower neonatal mortality to less than 12/1000 births and under-five deaths to less than 25/1000 live births MDG5. Improve maternal health Reduce the maternal mortality ratio by three-quarters SDG 3.1. Reduce global maternal mortality ratio to less than 70/100,000 live births MDG6. Combat HIV/AIDS, malaria & other diseases have halted and begin to reverse the spread SDG 3.3. End epidemics of AIDS, TB, malaria and other communicable diseases 2

lom Jo bia Vie rdan t Ho Nam Do mi P ndu nic hili ra an ppi s Re nes pu bli c E Ind gyp on t Mo esia Z i m roc ba co bw Er e itre Ne a p Gh al a Ma Bo na da livi ga a sc ar H S a Ba ene iti ng ga lad l es h K en Un Eth ya ite dr iop ia ep ub C Con a lic m go of ero Ta on nz a Le nia so Ug tho Ca and Bu mb a rki od na ia Fa Ma so l Za awi mb i Ni a g Rw er an Ni da ge Gu ria in Mo C ea za ha mb d iqu e Co Infant Mortality Rates per 1000 live births the world each year. A role for social determinants? Figure 2.1: Inequity in infant mortality rates between countries and within countries by mother s education. 160 140 120 40 20 Source: WHO CSDH report (2008) No education 100 80 60 Secondary or higher 0

A thought experiment. Let s assume that the education-based gradients in infant mortality reflect a causal effect and you were charged with eliminating these inequalities what would you do? Infant Mortality Rates per 1000 live births 160 140 120 100 80 60 40 20 0 Colombia Jordan Source: WHO CSDH report (2008) No education Viet Nam Honduras Philippines Dominican Republic Egypt Indonesia Morocco Zimbabwe Eritrea Nepal Ghana Bolivia Madagascar Haiti Senegal Bangladesh Kenya Ethiopia Congo Cameroon United Republic of Tanzania Lesotho Uganda Secondary or higher Cambodia Burkina Faso Malawi Zambia Niger Rwanda Nigeria Guinea Chad Mozambique

A thought experiment. How should we intervene to reduce educational-based inequalities in infant mortality? A. Increase secondary or higher education by making it free B. Increase secondary education by making it compulsory C. Increase secondary education by increasing school quality D. Build more secondary schools

A thought experiment. How should we intervene to reduce educational-based inequalities in infant mortality? A. Increase secondary or higher education by making it free B. Increase secondary education by making it compulsory C. Increase secondary education by increasing school quality D. Build more secondary schools E. Increase access to maternal care among less-educated women F. Increase immunization among kids of less-educated mothers G. Increase access to family planning H. Increase access to household resources among less-educated mothers

How should we intervene to reduce educational-based inequalities in infant mortality? A. Increase secondary or higher education by making it free B. Increase secondary education by making it compulsory C. Increase secondary education by increasing school quality D. Build more secondary schools E. Increase access to maternal care among less-educated women F. Increase immunization among kids of less-educated mothers G. Increase access to family planning H. Increase access to household resources among less-educated mothers I. All of the above? J. Some of the above K. None of the above? A thought experiment.

help!

...in a feast of descriptive studies of socio-economic causes of ill health we still face a famine of evaluative intervention studies (Bonneaux, 2008) Causal evidence Consequentialist evidence Descriptive evidence 9

strategic questions + data + empirical methods consequentialist evidence

strategic questions + data + empirical methods à consequentialist evidence Discussions between academics and knowledge users to identify relevant research questions that can be answered

strategic questions + data + empirical methods à consequentialist evidence Discussions between academics and knowledge users to identify relevant research questions that can be answered We collect longitudinal data on social policies related to poverty, income and gender inequality for all LMICs

strategic questions + data + empirical methods à consequentialist evidence Discussions between academics and knowledge users to identify relevant research questions that can be answered We collect longitudinal data on social policies related to poverty, income and gender inequality for all LMICs Breastfeeding breaks at work (1995-current)

Were breastfeeding breaks guaranteed at work? 1995 2014 15

strategic questions + data + empirical methods à consequentialist evidence Discussions between academics and knowledge users to identify relevant research questions that can be answered We collect longitudinal data on social policies related to poverty, income and gender inequality for all LMICs Breastfeeding breaks at work (1995-current) Minimum wage (1999-current)

How have minimum wages evolved over time? Americas East Asia & Pacific Europe & Central Asia 1500 Monthly minimum wage per capita (constant 2011 PPP USD) 1000 500 0 1500 1000 500 Middle East & North Africa South Asia Sub-Saharan Africa 0 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 Year 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013

strategic questions + data + empirical methods à consequentialist evidence Discussions between academics and knowledge users to identify relevant research questions that can be answered We collect longitudinal data on social policies related to poverty, income and gender inequality for all LMICs Breastfeeding breaks at work (1995-current) Minimum wage (1999-current) Maternal and paternal leave policies (1995-current) Minimum age of marriage (1995-current) Family cash benefits (1999-current) Child labour (1995-current)

strategic questions + data + empirical methods à consequentialist evidence Discussions between academics and knowledge users to identify relevant research questions that can be answered We collect longitudinal data on social policies related to poverty, income and gender inequality for all LMICs Join policy data to survey data from harmonized DHS/MICS or other sources to create multilevel datasets

strategic questions + data + empirical methods à consequentialist evidence Discussions between academics and knowledge users to identify relevant research questions that can be answered We collect longitudinal data on social policies related to poverty, income and gender inequality for all LMICs Join policy data to survey data from harmonized DHS/MICS or other sources to create multilevel datasets Apply empirical methods, including those commonly used in epidemiology and economics, to rigorously evaluate the impact of policy reforms on health and health inequality

Increased leave lowered infant mortality. Change in mortality/1000 live births for each month of paid leave* 0-2 -4-6 -8-10 -12-14 Neonatal mortality -2.8 Infant mortality -7.8 *results were robust to adjustment for individual, household, and country-level characteristics, including the wage replacement rate, GDP per capita, female labor force participation, government health expenditure per capita, and total health expenditure per capita

This is hard. We measure national policies, although there may be subnational variations in social policy approaches Comprehensive information about implementation is limited globally we try to measure intention-to-treat effects Cross-national data is limited at the individual- or householdlevels for specific health targets (e.g., maternal mortality) Standard threats to internal validity apply, including the potential for unmeasured confounding & measurement error

Recommendations. Invest in global data infrastructure for tracking trends in social policy approaches and development related targets Integrate quasi-experimental methods (i.e., ITS, DD, IV, RD) into our public health & epidemiologic pedagogy Involve knowledge users in the research process to help identify research gaps and specify policy-relevant questions Encourage reviews for systematically synthesizing results, identifying research gaps, understanding heterogeneity, and reducing redundancies

THANKS! KEY COLLABORATORS: Efe Atabay, John Frank, Mohammad Hajizadeh, Sam Harper, Jody Heymann, Jay Kaufman, Alissa Koski, Lauren Maxwell, José Mendoza Rodriguez, Erin Strumpf, Ilona Vincent, and all of the research team PARTNER INSTITUTIONS: FUNDING: FOR FURTHER INFORMATION SEE WWW.MACHEQUITY.COM

The global MACHEquity team. McGill University Bristol University UCLA IIM, Bangalore Universidad Peruana Cayetano Heredia Human Sciences Research Council

1. IDENTIFY POLICY EXPERIMENTS. Prioritizing specific policy reforms with the potential to affect major sources of global morbidity and mortality prioritized by the UN Development Goals Quasi-experiments. Estimating policy impact, and inequalities by gender, SES, and urban-rural residence 2. EVALUATE. Mediation analysis. Examining mechanisms through which policies influence health targets Cost-effectiveness. Comparing the costs and benefits of policies that have a robust effect on health 4. FEEDBACK. Refining research priorities based on knowledge created and changing priorities of network partners 3. SUPPORT EVIDENCE-BASED DECISION MAKING. Translating research findings for academic and nonacademic audiences and identifying practical solutions for improving socioeconomic development and health