galderma h i g h l i g h t s

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galderma 2 0 1 3 h i g h l i g h t s

Galderma, 2014. design and production:. Photos: Plainpicture, Thinkstock, istock, Nathalie Oundjian.

We are committed to delivering innovative medical solutions to meet the dermatological needs of people throughout their lifetime while serving healthcare professionals around the world.

galderma s TheraPeuTic areas galderma recognizes The importance Of having healthy SkiN at any age and is focused ON finding effective medical SOluTiONS for a whole range Of SkiN diseases and conditions. OnychOmycOsis Onychomycosis (or nail mycosis) is an increasingly common disorder, accounting for 20% of all nail diseases, affecting around 10% of the world population. acne Acne is a chronic inflammatory skin disease of the pilosebaceous gland, linked to changes in hormone levels, mostly seen in adolescents and young adults. skin cancer skin cancers relate to melanoma and non melanoma skin cancers (NMsC). galderma s focus is on NsMC including actinic keratosis (considered as precancerous lesions, basal cell carcinoma (BCC) and intra-epidermal squamous cell carcinoma (Bowen s disease). galderma develops solutions for the prevention and treatment of NMsC. rosacea Rosacea is a chronic inflammatory skin condition characterized by facial redness, which is firstly intermittent but then becomes permanent, associated in some cases to papulopustules. Other rare forms of rosacea include rhynophyma and ocular rosacea.

PsOriasis and Other steroid responsive dermatosis (srd) Psoriasis is a chronic, inflammatory skin disorder characterized by red, scaly and sometimes itchy patches Atopic dermatitis, also known as atopic eczema, is an inflammatory relapsing and itchy skin disease associated with xerosis affecting mainly children as well as adults. key brands 5 galderma S TheraPeuTic areas rare skin diseases galderma is currently exploring the treatment of some rare skin diseases such as congenital ichtyosis including lamellar ichtyosis, and Cutaneous t Cell lymphomas and gorlin syndrome. Pigmentary disorders Pigmentary disorders are characterized by an increase or decrease in skin pigment. Melasma (commonly known as the pregnancy mask) is the most frequent disorder. skin senescence skin aging is caused by the passage of time, but also by chronic UV exposure (actinic damage).

2013 key figures innovation, New PrOducT launches and geographic expansion are The PillarS Of The company S consistent PerfOrmaNce. looking ahead, demographic evolution and a holistic approach TO SkiN health are expected TO have SigNificaNT, POSiTive impact ON galderma S activities. sales by business lines With three core businesses and a global approach to skin health, meeting a full range of dermatological needs, galderma s various activities leverage the company s powerful research and innovation capacities. Medical solutions of scientifically proven efficacy are the cornerstone of these three businesses: Prescription, self-medication and Aesthetic & Corrective solutions. 1.653 billion euros total sales and OVerall growth +3.9% Versus 2012, as reported and at Published exchange rates. PResCRiPtiON 47% self-medication 33% AesthetiC & CORReCtiVe 20% 47% 20% 33% 4 PrOducts in the top 20 On the dermatology market* #5 Oracea #7 epiduo #11 differin #20 loceryl #1 Source: company data at the end of december 2013 - at published rates. except: * ims midas Panel - d+j1+j2a (dermatology only) - quarterly report - mat Q3 2013-39 countries. ** ims health - monthly database, all countries selected - Topical anti acne market - Nov. 2012 mat, retail rx market - at sales manufacturer local currency dollar value. 5 R&d centers (France, switzerland, sweden, UsA, Japan). 12 chemical entities in development phase. 167 product approvals accross the world.

7 strong growth Of key brands in the 3 galderma businesses +17.3% +15.8% +30.7% azzalure Botulinum toxin-based Azzalure serves the expanding mainstream demand for efficient, gratifying aesthetic solutions, with particularly strong growth in Australia, Brazil and europe. CeTaPHIl With new launches and a growing range of specialized, disease-specific products, the leading brand of cleansing and moisturizing skincare is endorsed by dermatologists. 2013 key figures epiduo Antibiotic-free, epiduo is the most-prescribed topical brand for acne treatment in the world.** 5,000 employees in more than 80 countries and 34 affiliates split by OrganiZatiOn 53 % WOmen 47% men 7% CORPORAte services 15% scientific division 14% AsiA-PACiFiC 18% europe, Middle-eAst, AFRiCA 12% latin AMeRiCA 12% NORth AMeRiCA 22% MANUFACtURiNg & technical OPeRAtiONs 53 new patent applications filed. of sales invested each year to discover and develop new products and access innovative technologies. 19% 200 5 million units produced by galderma. 155 million of them were manufactured at its own facilities. Manufacturing sites (France, switzerland, sweden, Canada, Brazil).

2013 key facts mirvaso goes live right after securing fda approval, Mirvaso, the first topical gel for reducing facial erythema associated with rosacea, launches in the Us. metvix in canada metvix sales increased by more than 40% after being used by the cancer treatment center of a leading Canadian hospital. expanding self-medication POrtfOliO following the acquisition of swiss dermatology leader spirig, galderma has entered two new markets: Austria and slovakia. actinica PrOtectiOn endorsed by the skin cancer foundation and launched in australia, Actinica is designed for patients at risk of actinic keratosis and non melanoma skin cancers. cetaphil restoraderm in the middle east the latest disease-specific cetaphil product, Restoraderm, led the way for the launch of the rest of the range in the Middle east. Source: company data at the end of december 2013 - at published rates. Pediatric dermatology for the first time, galderma exhibited at the World congress for Pediatric dermatology, organized by the international society of Pediatric dermatology (ispd).

9 first a&c meeting in china nearly 200 doctors, including 29 speakers, from mainland China, taiwan and hong Kong, gathered in shanghai for the 1 st greater China Aesthetics summit. 2013 key facts PrOduct launches in latin america in brazil, emervel was launched with an impactful marketing campaign, the power of positive transformation. in Mexico, market-size opportunity and a new Onylaq (loceryl) communication platform led to a product re-launch. new a&c VisiOn a new vision and branding for galderma s A&C portfolio shows an emotional dimension beyond aesthetic enhancement. galderma branding and digital Presence a new logo, new visuals, and a redesigned galderma.com website better showcase the company as the people-centric skin expert. euroderm and latinaderm as euroderm celebrated its 10 th edition, the first latinaderm excellence training Program gathered 70 residents in dermatology from all over the latin American continent.

galderma 2013 HIGHlIGHTS WOrldWide galderma S reach NOw exceeds 80 countries, with 34 affiliates and exclusive representatives ThrOughOuT The world. 2013 sales by region Source: company data at the end of december 2013 - at published rates. 43% NOrTH america 17% asia PaCIfIC 12% latin america 28% emea canada showed solid growth notably with highperforming brands epiduo (+35.5%) and Cetaphil (+9%). brazil (+12.4% of sales) is the company s second biggest subsidiary, with a broad portfolio of medical solutions and leadership recognition among doctors and patients.

latin america argentina Brazil chile colombia mexico venezuela north america canada united STaTeS Of america asia-pacific australia china hong kong india JaPaN PhiliPPiNeS SOuTh korea SiNgaPOre TaiwaN ThailaNd 11 galderma 2013 highlights worldwide europe - middle east africa austria Belgium france germany greece italy POlaNd POrTugal russia SlOvakia SOuTh africa SPaiN SwedeN SwiTzerlaNd The NeTherlaNdS united kingdom switzerland with the acquisition of spirig, galderma is now the leading dermatology company in the country and shows a high growth potential in self-medication worldwide. china is set to become the world s 2 nd dermatology market in 2015 and continues to show strong growth (+41.6% of sales) while deploying the company s promising three-business strategy. australia is a market where per capita expenditure for dermatology products remains particularly high. galderma reports solid growth (+19.9%) supported by key drivers such as the dysport, Restylane, Cetaphil and epiduo brands. find all galderma OfficeS around The world ON www.galderma.com